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Expression Of Matrix Metalloproteinases Mmps And Their Tissue Inhibitors Timps In Bovine Placental Cells In Vivo And In Vitro
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Book Synopsis Expression of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in bovine placental cells in vivo and in vitro by : Marc Dilly
Download or read book Expression of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in bovine placental cells in vivo and in vitro written by Marc Dilly and published by Cuvillier Verlag. This book was released on 2011-04-26 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis is submitted as a cumulative thesis with the main issue of elucidating potential functions and the regulation of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the bovine placenta. The thesis consists of two parts; each part being covered in one original paper published in peer reviewed journals. The first part analyses the involvement of MMPs/TIMPs in restricted trophoblast invasion/migration in respect to signal transduction, cell motility and proliferation in bovine trophoblast cells in vitro. The second part contains results of in vivo studies concerning the localization and expression of the MMP/TIMP system in different experimental groups and its possible involvement in the aetiology of retained fetal membranes (RFM).
Book Synopsis Expression and Localization of Matrix Metalloproteinases (MMPs) -2, -9, -14 (MT-MMP-1) and the Tissue Inhibitors of Metalloproteinaises (TIMPs) in Human Placenta and Some Malignant Tumors by : Tiina Hurskainen
Download or read book Expression and Localization of Matrix Metalloproteinases (MMPs) -2, -9, -14 (MT-MMP-1) and the Tissue Inhibitors of Metalloproteinaises (TIMPs) in Human Placenta and Some Malignant Tumors written by Tiina Hurskainen and published by . This book was released on 1996 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Matrix Metalloproteinase Biology by : Irit Sagi
Download or read book Matrix Metalloproteinase Biology written by Irit Sagi and published by John Wiley & Sons. This book was released on 2015-08-03 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing recent advances in the field of matrix metalloproteinase (MMP) research from a multidisciplinary perspective, Matrix Metalloproteinase Biologyis a collection of chapters written by leaders in the field of MMPs. The book focuses on the challenges of understanding the mechanisms substrate degradation by MMPs, as well as how these enzymes are able to degrade large, highly ordered substrates such as collagen. All topics addressed are considered in relation to disease progression including roles in cancer metastasis, rheumatoid arthritis and other inflammatory diseases. The text first provides an overview of MMPs, focusing on the history, the development and failures of small molecule inhibitors in clinical trials, and work with TIMPS, the endogenous inhibitors of MMPs. These introductory chapters establish the foundation for later discussion of the recent progress on the design of different types of inhibitors, including novel antibody based therapeutics. The following section emphasizes research using novel methods to further the study of the MMPs. The third and final section focuses on in vivo research, particularly with respect to cancer models, degradation of the extracellular matrix, and MMP involvement in other disease states. Written and edited by leaders in the field, Matrix Metalloproteinase Biology addresses the rapidly growth in MMP research, and will be an invaluable resource to advanced students and researchers studying cell and molecular biology.
Book Synopsis Matrix Metalloproteinases in Tissue Remodelling and Inflammation by : Vincent Lagente
Download or read book Matrix Metalloproteinases in Tissue Remodelling and Inflammation written by Vincent Lagente and published by Springer Science & Business Media. This book was released on 2008-11-07 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides new advances regarding the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs give new insights in the relationship between activation of inflammatory cells and tissue remodelling and advise new therapeutics possibilities to the treatment of inflammatory disease. The volume has an international authorship and is written by leading experts in the field.
Book Synopsis Matrix Metalloproteinases (MMPs) and Their Specific Tissue Inhibitors (TIMPs) in Mature Human Odontoblasts and Pulp Tissue by : Heidi Palosaari
Download or read book Matrix Metalloproteinases (MMPs) and Their Specific Tissue Inhibitors (TIMPs) in Mature Human Odontoblasts and Pulp Tissue written by Heidi Palosaari and published by . This book was released on 2003 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Matrix Metalloproteinases and TIMPs by : J. F. Woessner
Download or read book Matrix Metalloproteinases and TIMPs written by J. F. Woessner and published by Oxford University Press on Demand. This book was released on 2000 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The matrix metalloproteinases (MMPs) are a large family of enzymes that breakdown different components of the extracellular matrix. Their catalytic activity is dependent a metal ion, usually zinc. This issue of the Protein Profiles covers the sequence information, three-dimensional structures, activation, protein substrates, specificity requirements, inhibition, and biological roles of all the currently identified MMPs. The action of these enzymes must be carefully regulated. One way the cell does this, is by releasing inhibitory molecules known as tissue inhibitors of metalloproteinases (TIMPs). This volume contains information on the sequences, three-dimensional structures, and biological roles of the 4 known classes of TIMP. Matrix metalloproteinases will therefore be an invaluable source of data for all researchers interested in MMPs and TIMPs.
Book Synopsis Matrix Metalloproteinases In Health And Disease: Sculpting The Human Body by : Constance E Brinckerhoff
Download or read book Matrix Metalloproteinases In Health And Disease: Sculpting The Human Body written by Constance E Brinckerhoff and published by World Scientific. This book was released on 2017-05-05 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biochemistry and cell biology of Matrix Metalloproteinases (MMPs) are not necessarily straightforward, but basic information on the history of these enzymes, their various functions that extend far beyond the cleaving of the extracellular matrix, and the complex mechanisms that control their expression are valuable to both scientists and clinicians. This volume summarizes the salient features and functions of MMPs and applies this information in a practical manner in order to understand how they contribute to normal physiology and pathology of selected diseases. Chapters by noted clinicians Jean-Michel Dayer, MD in rheumatology, Jian Cao, MD in oncology, and Peter Libby, MD in cardiology, represent important practical and clinically-oriented contributions.
Book Synopsis Inhibition of Matrix Metalloproteinases by : Robert A. Greenwald
Download or read book Inhibition of Matrix Metalloproteinases written by Robert A. Greenwald and published by . This book was released on 1999 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers from a multidisciplinary conference convened to discuss mechanisms of action, pharmacology, models for drug development, and recent positive clinical trial data relating to the inhibition of collagenases and related metalloproteinases matrix (MMPs). Excess metalloproteinase activity has been identified in many disease processes, and finally products for the specific use as metalloproteinase inhibitors are about to be marketed. In this book, two novel themes are explored: the arguments for and against broad-spectrum versus specific MMP inhibitors, and the potential usefulness of chairside diagnostic kits for clinical determination of excessive MMP activity.
Download or read book Matrix Metalloproteinases written by and published by Elsevier. This book was released on 1998-03-27 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters in this book thoroughly cover the structure, regulation, and function of matrix metalloproteinases, and provide information on the latest strategies to inhibit enzyme activity. This work will be an indispensable reference tool for investigators with an interest in extracellular matrix biology, matrix turnover, enzymology and biochemistry of proteinases, developmental biology, pathology, and therapeutic interventions. - Provides state-of-the-art information on a field with broad implications to many areas of biology - Includes detailed coverage of the structure and regulation of all major matrix metalloproteinases - Chapters focus on a timely and expanding field - Topics have direct relevance to understanding human disease pathology of cancer, arthritis, and vascular disease - Discusses latest strategies used in the development of new therapeutics to inhibit metalloproteinase activity
Book Synopsis Inhibition of Matrix Metalloproteinases by : Robert A. Greenwald
Download or read book Inhibition of Matrix Metalloproteinases written by Robert A. Greenwald and published by . This book was released on 1994 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the January 1994 conference. Topics include the disparity between the in vivo and in vitro actions of various inhibitors, matrix metalloproteinase (MMP) gene expression, mechanisms and applications of tissue inhibitor metalloproteinases, medical and dental tetracyclines, and MMPs in c
Book Synopsis Proteases in Health and Disease by : Sajal Chakraborti
Download or read book Proteases in Health and Disease written by Sajal Chakraborti and published by Springer Science & Business Media. This book was released on 2013-12-04 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases will be discussed. The book highlights the roles of both intracellular and extracellular proteases in health and disease.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 2214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Matrix Metalloproteinases in Tissue Remodelling and Inflammation by : Vincent Lagente
Download or read book Matrix Metalloproteinases in Tissue Remodelling and Inflammation written by Vincent Lagente and published by Birkhäuser. This book was released on 2009-08-29 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides new advances regarding the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs give new insights in the relationship between activation of inflammatory cells and tissue remodelling and advise new therapeutics possibilities to the treatment of inflammatory disease. The volume has an international authorship and is written by leading experts in the field.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2002 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2730 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Journal of Reproduction & Fertility by :
Download or read book Journal of Reproduction & Fertility written by and published by . This book was released on 1992 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt:
