Experimental Approaches To Diabetic Retinopathy

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Experimental Approaches to Diabetic Retinopathy

Author : H.-P. Hammes
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805592752
Total Pages : 241 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Experimental Approaches to Diabetic Retinopathy by : H.-P. Hammes

Download or read book Experimental Approaches to Diabetic Retinopathy written by H.-P. Hammes and published by Karger Medical and Scientific Publishers. This book was released on 2010 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume sets the stage for clinical experts working with diabetic patients as well as for researchers by describing the clinical presentations of retinopathy and their anatomical and functional correlates. It reviews currently available experimental models in animals. The impact of retinal pericytes, neuroglia and, specifically, Mller cells are discussed in detail. The volume addresses a variety of current scientific discussions about mechanisms of damage such as growth factors and the VEGF/PEDF balance in the diabetic eye, the ocular renin-angiotensin system, and leukocyte interactions with the microvasculature among others. Stem and progenitor cells in the retina are discussed as potential directions for future investigation. The final chapters return to emerging clinical aspects, including current approaches to retinopathy as a predictor of cardiovascular risk and how knowledge can be translated from bench to bedside. Bridging a widening gap in medical research between basic scientists, who may lose sight of the clinical presentations, and clinical researchers, who may grow unaware of the limits of experimental models, this volume serves as a reference platform for endocrinologists, diabetologists, ophthalmologists, as well as for scientists involved in clinical and basic research in diabetic retinopathy and other vascular complications of diabetes.

Diabetic Retinopathy

Author : Guei-Sheung Liu
Publisher : Springer Nature
ISBN 13 : 1071632558
Total Pages : 223 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Diabetic Retinopathy by : Guei-Sheung Liu

Download or read book Diabetic Retinopathy written by Guei-Sheung Liu and published by Springer Nature. This book was released on 2023-06-16 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume provides various cellular and experimental animal models and research methodologies to understand the complex interrelated pathophysiological mechanisms triggered by hyperglycemia that underlie the development of diabetic retinopathy. The book covers methods for understanding the pathogenesis of diabetic retinopathy, detection and screening of biomarkers in diabetic retinopathy, as well as novel technologies for diabetic retinopathy management. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Diabetic Retinopathy: Methods and Protocols serves as an invaluable resource for scientists and clinicians who are interested in the area of ophthalmology research.

Diabetic Retinopathy

Author : Elia Duh
Publisher : Springer Science & Business Media
ISBN 13 : 1597455636
Total Pages : 494 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Diabetic Retinopathy by : Elia Duh

Download or read book Diabetic Retinopathy written by Elia Duh and published by Springer Science & Business Media. This book was released on 2008-10-08 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetic retinopathy is the most common microvascular complication of diabetes. It remains a major cause of new-onset visual loss in the United States and other industrialized nations. In Diabetic Retinopathy, Elia Duh and a panel of internationally recognized experts comprehensively assess the current state of knowledge regarding the clinical management of DR as well as its underlying mechanisms. The authors outline the current understanding of diabetic retinopathy from the perspective of clinical practice, while reviewing the multi-factorial pathogenesis and pathophysiology of DR from the standpoint of biomedical research. Also included is a discussion of emerging concepts relating to the management and treatment of DR. Informative and highly-practical, Diabetic Retinopathy provides ophthalmologists, diabetologists, endocrinologists, and internists with a highly readable guide not only to understanding diabetic retinopathy, but also to its optimal clinical management.

Clinical Strategies in the Management of Diabetic Retinopathy

Author : Francesco Bandello
Publisher : Springer Science & Business
ISBN 13 : 3642545033
Total Pages : 194 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Clinical Strategies in the Management of Diabetic Retinopathy by : Francesco Bandello

Download or read book Clinical Strategies in the Management of Diabetic Retinopathy written by Francesco Bandello and published by Springer Science & Business. This book was released on 2014-04-29 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of effective treatments for diabetic retinopathy (DR), a new era in the management of DR has been opened up. Amid the deluge of approved treatments and promising new strategies, however, clinicians may find it difficult to choose the appropriate practice in each individual case. The purpose of this easy-to-use and richly illustrated manual is to assist ophthalmologists in making decisions in the entire management of DR based on the best available evidence. Practical and complete recommendations are provided to guide clinicians in diagnosis, decision-making, and treatment. The manual includes practical algorithms and case histories relating to all stages of DR that clearly explain the progression of the disease and will help the clinician to choose the best therapeutic approach. It will be an ideal resource for ophthalmologists aiming to provide optimal clinical management for this sight-threatening disease.

Anti-Angiogenic Therapy in Ophthalmology

Author : Andreas Stahl
Publisher : Springer
ISBN 13 : 3319240978
Total Pages : 193 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Anti-Angiogenic Therapy in Ophthalmology by : Andreas Stahl

Download or read book Anti-Angiogenic Therapy in Ophthalmology written by Andreas Stahl and published by Springer. This book was released on 2016-05-13 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases.

Retinal Pharmacotherapeutics

Author : Q.D. Nguyen
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318055654
Total Pages : 408 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Retinal Pharmacotherapeutics by : Q.D. Nguyen

Download or read book Retinal Pharmacotherapeutics written by Q.D. Nguyen and published by Karger Medical and Scientific Publishers. This book was released on 2015-10-27 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of pharmacotherapeutics in the management of retinal diseases is rapidly evolving, and a favorable therapy for the patient. Today anti-VEGF agents are used for a range of indications from inflammation-related choroidal neovascularization to macular edema secondary to retinal vein occlusion or diabetic retinopathy. Beyond VEGF, there is an array of target areas under investigation – not only for vascular pathologies such as age-related macular degeneration and diabetic eye disease, but also for degenerative, infectious and inflammatory retinal conditions. This publication discusses many aspects from basic research on the retina, to animal models for retinal drug delivery, retinal diseases that are amenable to pharmacotherapy and also drugs and mechanisms in retinal diseases. Anyone concerned with the management of retinal diseases - the general ophthalmologist and the retina specialist alike – will find this book indispensable reading.

New Mechanisms of Action of Natural Antioxidants in Health and Disease

Author : Silvana Hrelia
Publisher : MDPI
ISBN 13 : 3039362682
Total Pages : 168 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis New Mechanisms of Action of Natural Antioxidants in Health and Disease by : Silvana Hrelia

Download or read book New Mechanisms of Action of Natural Antioxidants in Health and Disease written by Silvana Hrelia and published by MDPI. This book was released on 2020-07-03 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.

27-Gauge Vitrectomy

Author : Mitrofanis Pavlidis
Publisher : Springer
ISBN 13 : 3319202367
Total Pages : 463 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis 27-Gauge Vitrectomy by : Mitrofanis Pavlidis

Download or read book 27-Gauge Vitrectomy written by Mitrofanis Pavlidis and published by Springer. This book was released on 2015-10-01 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides step-by-step instructions on how to operate with 27G instrumentation in a wide range of surgical indications, including vitreous floaters, macular holes, dropped nucleus, retinal detachment, diabetic retinopathy, submacular hemorrhage, retinopathy of prematurity and much trauma. All surgeries are approached in cookbook fashion, with initial coverage of the “ingredients” (devices and instruments) and then meticulous description of preparation and performance with supporting photographs, drawings and videos. In addition, the differences and benefits in comparison with 23G and 25G vitrectomy are highlighted. Small-gauge vitrectomy has radically changed the ways in which vitrectomy is performed. 27G vitrectomy is the most recent and most exciting development in small-gauge vitrectomy. The healing time is faster but the small diameter prolongs the duration of surgery. This obstacle has been overcome with powerful new vitrectomy machines and revolutionary vitreous cutters with two cutting blades making 27G vitrectomy as fast as 25G. This new equipment has expanded the indications for 27G surgeries immensely from detachment surgery to retinopathy of prematurity and the advent of new instruments may make 27G the gold standard in the future. This book, written by authors with huge experience in 27G vitrectomy, will enable surgeons to fully exploit its advantages.

Management of Diabetic Retinopathy

Author : F. Bandello
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318060429
Total Pages : 194 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Management of Diabetic Retinopathy by : F. Bandello

Download or read book Management of Diabetic Retinopathy written by F. Bandello and published by Karger Medical and Scientific Publishers. This book was released on 2017-04-20 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently developed diagnostic and therapeutic technologies such as OCT-angiography and small gauge vitrectomy have influenced the modern treatment of diabetic retinopathy. This volume provides a summary of the state-of-the-art evidence-based approach to managing complications that may occur with diabetic retinopathy. It offers the latest information on pathogenesis and diagnosis, and highly experienced clinicians review the results of relevant randomized clinical trials that serve as the basis of current therapy. The book provides not only a summary of data from randomized trials but also an analysis and interpretation by internationally renowned experts. Ophthalmology residents, fellows, and practicing clinicians will find this book to be a useful reference when seeking evidence-based treatment strategies for various complications of diabetic retinopathy. It is also for researchers identifying new avenues of drug developments and for insurance professionals and health care policy administrators who are establishing evidence-based therapy guidelines for therapeutic intervention.

Diabetes and Fundus OCT

Author : Ayman S. El-Baz
Publisher : Elsevier
ISBN 13 : 0128174412
Total Pages : 434 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Diabetes and Fundus OCT by : Ayman S. El-Baz

Download or read book Diabetes and Fundus OCT written by Ayman S. El-Baz and published by Elsevier. This book was released on 2020-04-02 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes and Fundus OCT brings together a stellar cast of authors who review the computer-aided diagnostic (CAD) systems developed to diagnose non-proliferative diabetic retinopathy in an automated fashion using Fundus and OCTA images. Academic researchers, bioengineers, new investigators and students interested in diabetes and retinopathy need an authoritative reference to bring this multidisciplinary field together to help reduce the amount of time spent on source-searching and instead focus on actual research and the clinical application. This reference depicts the current clinical understanding of diabetic retinopathy, along with the many scientific advances in understanding this condition. As the role of optical coherence tomography (OCT) in the assessment and management of diabetic retinopathy has become significant in understanding the vireo retinal relationships and the internal architecture of the retina, this information is more critical than ever. Includes unique information for academic clinicians, researchers and bioengineers Provides insights needed to understand the imaging modalities involved, the unmet clinical need that is being addressed, and the engineering and technical approaches applied Brings together details on the retinal vasculature in diabetics as imaged by optical coherence tomography angiography and automated detection of retinal disease

Fundamentals and Methods of Machine and Deep Learning

Author : Pradeep Singh
Publisher : John Wiley & Sons
ISBN 13 : 1119821886
Total Pages : 480 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Fundamentals and Methods of Machine and Deep Learning by : Pradeep Singh

Download or read book Fundamentals and Methods of Machine and Deep Learning written by Pradeep Singh and published by John Wiley & Sons. This book was released on 2022-02-01 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: FUNDAMENTALS AND METHODS OF MACHINE AND DEEP LEARNING The book provides a practical approach by explaining the concepts of machine learning and deep learning algorithms, evaluation of methodology advances, and algorithm demonstrations with applications. Over the past two decades, the field of machine learning and its subfield deep learning have played a main role in software applications development. Also, in recent research studies, they are regarded as one of the disruptive technologies that will transform our future life, business, and the global economy. The recent explosion of digital data in a wide variety of domains, including science, engineering, Internet of Things, biomedical, healthcare, and many business sectors, has declared the era of big data, which cannot be analysed by classical statistics but by the more modern, robust machine learning and deep learning techniques. Since machine learning learns from data rather than by programming hard-coded decision rules, an attempt is being made to use machine learning to make computers that are able to solve problems like human experts in the field. The goal of this book is to present a??practical approach by explaining the concepts of machine learning and deep learning algorithms with applications. Supervised machine learning algorithms, ensemble machine learning algorithms, feature selection, deep learning techniques, and their applications are discussed. Also included in the eighteen chapters is unique information which provides a clear understanding of concepts by using algorithms and case studies illustrated with applications of machine learning and deep learning in different domains, including disease prediction, software defect prediction, online television analysis, medical image processing, etc. Each of the chapters briefly described below provides both a chosen approach and its implementation. Audience Researchers and engineers in artificial intelligence, computer scientists as well as software developers.

Müller Cells in the Healthy and Diseased Retina

Author : Andreas Reichenbach
Publisher : Springer
ISBN 13 : 9781489985026
Total Pages : 0 pages
Book Rating : 4.9/5 (85 download)

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Book Synopsis Müller Cells in the Healthy and Diseased Retina by : Andreas Reichenbach

Download or read book Müller Cells in the Healthy and Diseased Retina written by Andreas Reichenbach and published by Springer. This book was released on 2014-11-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective - and prevent the destructive - mechanisms of gliosis.

Vitreoretinal Surgery

Author : Thomas H. Williamson
Publisher : Springer Science & Business Media
ISBN 13 : 364231872X
Total Pages : 435 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Vitreoretinal Surgery by : Thomas H. Williamson

Download or read book Vitreoretinal Surgery written by Thomas H. Williamson and published by Springer Science & Business Media. This book was released on 2013-05-22 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of a highly successful textbook that in many areas has become the preferred manual of vitreoretinal surgery. It provides a complete guide to all common vitreoretinal surgical procedures and also covers diagnosis and other aspects of management. The book is designed to allow a trainee or professional vitreoretinal surgeon to determine the best methodology in individual cases. In order to acquaint the reader with different opinions, “surgical pearls” have been contributed by other international experts in the field. These have proved popular in the past as an illustration of alternative methods, without detracting from the overall method described by the main author. Vitreoretinal Surgery will continue to prove particularly popular amongst trainees, but will also be of value to practicing professionals who need help in the management of difficult and rare cases. The text is backed up by the provision of videos of some aspects of the surgery.

Ophthalmology

Author : Pinakin Davey
Publisher : BoD – Books on Demand
ISBN 13 : 9535117211
Total Pages : 608 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Ophthalmology by : Pinakin Davey

Download or read book Ophthalmology written by Pinakin Davey and published by BoD – Books on Demand. This book was released on 2014-09-03 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together both a review and updates in clinical and research areas. The chapters will be of interest to a wide audience. On one hand, the review and update of clinical practices will interest students and residents, on the other, cutting edge research chapters will be of interest to the researchers in the field. The book is divided into four parts: 1) Review and Updates in Diagnostic Testing, 2) Updates in Anterior Segment Diseases, 3) Updates in Posterior Segment Diseases, and 4) Updates in Research in Ophthalmology, Optometry and Vision Science. The chapters are written by experts and individuals with special interests in topics with a focus on clinical application and translational benefit to eye care.

Photocoagulation Treatment of Proliferative Diabetic Retinopathy

Author :
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Photocoagulation Treatment of Proliferative Diabetic Retinopathy by :

Download or read book Photocoagulation Treatment of Proliferative Diabetic Retinopathy written by and published by . This book was released on 1982 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Practical Manual of Diabetic Retinopathy Management

Author : Peter H. Scanlon
Publisher : John Wiley & Sons
ISBN 13 : 111905897X
Total Pages : 288 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis A Practical Manual of Diabetic Retinopathy Management by : Peter H. Scanlon

Download or read book A Practical Manual of Diabetic Retinopathy Management written by Peter H. Scanlon and published by John Wiley & Sons. This book was released on 2017-02-08 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence of diabetes is increasing worldwide at an alarming rate, and diabetic retinopathy is one of the most significant complications of diabetes. Packed with outstanding retinal photos, the second edition of this one-stop clinical manual offers a comprehensive overview of the diagnosis, treatment and long–term management of patients with diabetic eye disease. Edited and authored by world-renowned experts from leading centres of excellence, A Practical Manual of Diabetic Retinopathy Management presents evidence-based guidance relevant for a global audience of health-care professionals, including diabetologists, ophthalmologists, retinal screeners, optometrists, ophthalmic nurses, GPs, and medical students.

The Jobs of Tomorrow

Author : Mark A. Dutz
Publisher : World Bank Publications
ISBN 13 : 1464812233
Total Pages : 94 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis The Jobs of Tomorrow by : Mark A. Dutz

Download or read book The Jobs of Tomorrow written by Mark A. Dutz and published by World Bank Publications. This book was released on 2018-04-10 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: While adoption of new technologies is understood to enhance long-term growth and average per-capita incomes, its impact on lower-skilled workers is more complex and merits clarification. Concerns abound that advanced technologies developed in high-income countries would inexorably lead to job losses of lower-skilled, less well-off workers and exacerbate inequality. Conversely, there are countervailing concerns that policies intended to protect jobs from technology advancement would themselves stultify progress and depress productivity. This book squarely addresses both sets of concerns with new research showing that adoption of digital technologies offers a pathway to more inclusive growth by increasing adopting firms’ outputs, with the jobs-enhancing impact of technology adoption assisted by growth-enhancing policies that foster sizable output expansion. The research reported here demonstrates with economic theory and data from Argentina, Brazil, Chile, Colombia and Mexico that lower-skilled workers can benefit from adoption of productivity-enhancing technologies biased towards skilled workers, and often do. The inclusive jobs outcomes arise when the effects of increased productivity and expanding output overcome the substitution of workers for technology. While the substitution effect replaces some lower-skilled workers with new technology and more highly-skilled labor, the output effect can lead to an increase in the total number of jobs for less-skilled workers. Critically, output can increase sufficiently to increase jobs across all tasks and skill types within adopting firms, including jobs for lower-skilled workers, as long as lower-skilled task content remains complementary to new technologies and related occupations are not completely automated and replaced by machines. It is this channel for inclusive growth that underlies the power of pro-competitive enabling policies and institutions—such as regulations encouraging firms to compete and policies supporting the development of skills that technology augments rather than replaces—to ensure that the positive impact of technology adoption on productivity and lower-skilled workers is realized.