Experimental and Genetic Models of Hypertension

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Publisher :
ISBN 13 :
Total Pages : 664 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Experimental and Genetic Models of Hypertension by : Wybren de Jong

Download or read book Experimental and Genetic Models of Hypertension written by Wybren de Jong and published by . This book was released on 1994 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This volume is a worthy successor to volume 4 by virtue of its focus on the recent conceptual revolution in fundamental hypertension research. Without neglecting the heritage of earlier achievements, it highlights such brilliant breakthroughs in molecular genetics as the creation of transgenic animals as a source of a new pathogenesis of hypertension.A core of (patho)physiological mechanisms operative in experimental hypertension is provided, including several which act to maintain a normotensive state. The volume provides background and technical information on the use of different models of hypertension in a variety of animal species. A wealth of new information regarding the several different complications observed in genetic and other models of hypertension, as well as new animal models dedicated to these aspects, are also presented. Furthermore, new chapters addressing genotyping and the use of transgenics in hypertension are included.

Experimental and Genetic Models of Hypertension

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Publisher : Elsevier
ISBN 13 : 1483162990
Total Pages : 568 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Experimental and Genetic Models of Hypertension by : W. De Jong

Download or read book Experimental and Genetic Models of Hypertension written by W. De Jong and published by Elsevier. This book was released on 2013-06-02 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental and Genetic Models of Hypertension

Handbook of Hypertension

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Publisher :
ISBN 13 : 9780444903365
Total Pages : 549 pages
Book Rating : 4.9/5 (33 download)

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Book Synopsis Handbook of Hypertension by :

Download or read book Handbook of Hypertension written by and published by . This book was released on 1983 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Hypertension: Experimental and genetic models of hypertension

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (689 download)

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Book Synopsis Handbook of Hypertension: Experimental and genetic models of hypertension by :

Download or read book Handbook of Hypertension: Experimental and genetic models of hypertension written by and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Hypertension

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Publisher :
ISBN 13 : 9780444903419
Total Pages : 549 pages
Book Rating : 4.9/5 (34 download)

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Book Synopsis Handbook of Hypertension by : Wybren de Jong

Download or read book Handbook of Hypertension written by Wybren de Jong and published by . This book was released on 1984 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Hypertension

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Publisher :
ISBN 13 : 9780444903419
Total Pages : 642 pages
Book Rating : 4.9/5 (34 download)

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Book Synopsis Handbook of Hypertension by :

Download or read book Handbook of Hypertension written by and published by . This book was released on 1994 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Hypertension

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Publisher :
ISBN 13 : 9780444903419
Total Pages : pages
Book Rating : 4.9/5 (34 download)

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Book Synopsis Handbook of Hypertension by :

Download or read book Handbook of Hypertension written by and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Hypertension

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Publisher :
ISBN 13 : 9780444903419
Total Pages : pages
Book Rating : 4.9/5 (34 download)

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Book Synopsis Handbook of Hypertension by :

Download or read book Handbook of Hypertension written by and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Development of the Hypertensive Phenotype

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Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 720 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Development of the Hypertensive Phenotype by : David A. Blizard

Download or read book Development of the Hypertensive Phenotype written by David A. Blizard and published by Elsevier Science & Technology. This book was released on 1999 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. The present volume of the Handbook of Hypertension draws together knowledge on the endogenous (genetic) and exogenous (environmental) components contributing to the pathogenesis of essential hypertension. In the field of hypertension research, the importance of adopting a genetic approach to its phenomenology was recognized at an early stage. There was early debate concerning the nature of the genetic architecture underlying population variability in blood-pressure but today its polygenic nature is generally accepted and is reflected in the design and orientation of human investigations as well as in the heterogeneity of mechanisms that have been unearthed by exploration with diverse animal genetic models. Concurrently, epidemiological studies have emphasized the contribution of a variety of environmental factors in the etiology of hypertension. In particular, the contribution of dietary factors, smoking and lifestyle to the develop

Genetics of Hypertension

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Publisher : Elsevier Health Sciences
ISBN 13 : 0444514562
Total Pages : 284 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Genetics of Hypertension by : Anna F. Dominiczak

Download or read book Genetics of Hypertension written by Anna F. Dominiczak and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.

Comprehensive Hypertension E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323070671
Total Pages : 1247 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Comprehensive Hypertension E-Book by : Gregory Y. H. Lip

Download or read book Comprehensive Hypertension E-Book written by Gregory Y. H. Lip and published by Elsevier Health Sciences. This book was released on 2007-06-28 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Hypertensive Mechanisms

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Publisher :
ISBN 13 :
Total Pages : 840 pages
Book Rating : 4.:/5 (311 download)

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Book Synopsis Hypertensive Mechanisms by : W. Rascher

Download or read book Hypertensive Mechanisms written by W. Rascher and published by . This book was released on 1982 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics of Hypertension

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Publisher : Biota Publishing
ISBN 13 : 161504695X
Total Pages : 67 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Genetics of Hypertension by : Xi Cheng

Download or read book Genetics of Hypertension written by Xi Cheng and published by Biota Publishing. This book was released on 2015-08-01 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension, or elevated blood pressure, is a major risk factor for various cardiovascular, renal diseases, and stroke. The form of hypertension with no identifiable cause is referred to as Essential Hypertension. Familial studies indicate that Essential Hypertension is heritable and, thereby, classical genetic approaches have been applied on both human and other mammalian models of hypertension to map the locations of the allelic variants within quantitative trait loci for blood pressure. The post genome era has further elevated this area of research into large-scale genome-wide association studies of hypertension in humans. Collectively, these studies have resulted in the prioritization and cataloging of several genomic regions containing allelic variants as candidates linked or associated with essential hypertension. Further, they are providing evidence to suggest that the inheritance of hypertension is rather complex, encompassing multiple variants both within protein-coding and non-coding annotations, each of which may act independently or interactively with other genes and/or environmental factors to differentially regulate blood pressure. This book provides an overview of the various methods employed to study the genetics of hypertension and discuss the progress and prospects of this area of research that may contribute towards individualized clinical management of hypertension in the future.

Role of Brain Acetylcholine in Genetic and Experimental Rat Models of Hypertension

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ISBN 13 :
Total Pages : 806 pages
Book Rating : 4.:/5 (117 download)

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Book Synopsis Role of Brain Acetylcholine in Genetic and Experimental Rat Models of Hypertension by : Rachel Giuliano

Download or read book Role of Brain Acetylcholine in Genetic and Experimental Rat Models of Hypertension written by Rachel Giuliano and published by . This book was released on 1984 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Models for Study of Pathophysiological Mechanisms of Hypertension and Its Complications

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Publisher : Mdpi AG
ISBN 13 : 9783036563183
Total Pages : 0 pages
Book Rating : 4.5/5 (631 download)

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Book Synopsis Animal Models for Study of Pathophysiological Mechanisms of Hypertension and Its Complications by : Josef Zicha

Download or read book Animal Models for Study of Pathophysiological Mechanisms of Hypertension and Its Complications written by Josef Zicha and published by Mdpi AG. This book was released on 2023-01-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential hypertension is still an important health care problem. It is necessary to investigate its mechanisms in animal models. The potential clinical importance of such experimental research might be expected. This Special Issue concerned several important topics. First, several studies focused on the pathophysiological mechanisms responsible for blood pressure elevation during hypertension development, organ damage in chronic hypertension, and drugs targeting hypertension and/or its complications. Other studies were interested in the participation of central and peripheral blood pressure control, changes in vascular structure and function, and neural, humoral, and endocrine factors. Furthermore, the contribution of altered redox signaling, chronic inflammation, microbiome changes, and interactions of genetic and environmental factors were evaluated in multiple papers. Finally, special attention was paid to the progress in pharmacological tools for the control of hypertension and associated organ damage, genetic modifications to alter blood pressure levels, and non-pharmacological interventions attenuating hypertension or its complications. The original articles or reviews covered the interesting aspects of the pathophysiology of hypertension and associated end-organ damage, the use of various experimental hypertensive models, and the importance of specific environmental factors acting in distinct phases of the ontogeny. We especially appreciate the presentation of new ideas and the critical discussion of traditional theories.

Cardiac Hypertrophy and Failure

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Publisher :
ISBN 13 :
Total Pages : 718 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Cardiac Hypertrophy and Failure by : Bernard Swynghedauw

Download or read book Cardiac Hypertrophy and Failure written by Bernard Swynghedauw and published by . This book was released on 1990 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac insufficiency, a major cause of premature mortality, is a key focus of medical and pharmaceutical research. This book aims to bring clinicians and researchers up-to-date on recent biophysical, cellular physiological and molecular biological developments and their clinical applications.

Blood Pressure Increases in Genetic Models of Hypertension Followed by Collagen Deposition

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Publisher :
ISBN 13 :
Total Pages : 98 pages
Book Rating : 4.:/5 (957 download)

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Book Synopsis Blood Pressure Increases in Genetic Models of Hypertension Followed by Collagen Deposition by : Reza Hajjafar

Download or read book Blood Pressure Increases in Genetic Models of Hypertension Followed by Collagen Deposition written by Reza Hajjafar and published by . This book was released on 2000 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: