Experimental And Computational Fluid Dynamic Analysis Of Mixing Problems In Microfluidic Device

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Experimental and Computational Fluid Dynamic Analysis of Mixing Problems in Microfluidic Device

Author : Independently Published
Publisher :
ISBN 13 : 9781723801402
Total Pages : 68 pages
Book Rating : 4.8/5 (14 download)

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Book Synopsis Experimental and Computational Fluid Dynamic Analysis of Mixing Problems in Microfluidic Device by : Independently Published

Download or read book Experimental and Computational Fluid Dynamic Analysis of Mixing Problems in Microfluidic Device written by Independently Published and published by . This book was released on 2018-06-06 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Last four decades, with the increase in everlasting need there is still enormous advancements require in biological and chemical laboratory processes related to microfluidics devices. Microfluidics technology has found out plentiful uses at micro scale level e.g. flow cytometry, micro mixing, analysis of chemical and synthesis, particle sorting and generation of droplet. The use of various flow sensors and sensing systems at micro scale have drastically changed the scenario of higher end fields e.g. drug discovery, biomedical analyses, genetics, proteomics, biological and chemical reactions etc. Need of mixing is to take out high resolution and sensitive separations to distinguish very minute quantities of samples and reagents which makes this system comparatively inexpensive and requires short time analysis. The aim of the present work is to understand the physics of the mixing of fluids within micro channel using computational fluid dynamics and experimental technique. Four different types of mixing angles (300, 450, 600, 900) and three fluid mixing case of water+water; water+ethanol and water+glycerol were selected. The simulation results show that at 600 mixing angle minimum pressure drop and maximum outlet velocity was experienced as compared to other angles. At a constant inlet flow rate of 0.5 lph and at 600 degree angle the percentage variation between experimental and simulation results was observed to be in the range of 2.97-3.14% in water+water; 2.31-2.83% in water+ethanol and 19.62- 20.56% in water+glycerol case.

Process Analysis, Design, and Intensification in Microfluidics and Chemical Engineering

Author : Santana, Harrson Silva
Publisher : IGI Global
ISBN 13 : 1522571396
Total Pages : 367 pages
Book Rating : 4.5/5 (225 download)

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Book Synopsis Process Analysis, Design, and Intensification in Microfluidics and Chemical Engineering by : Santana, Harrson Silva

Download or read book Process Analysis, Design, and Intensification in Microfluidics and Chemical Engineering written by Santana, Harrson Silva and published by IGI Global. This book was released on 2019-01-18 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics represent great potential for chemical processes design, development, optimization, and chemical engineering bolsters the project design of industrial processes often found in large chemical plants. Together, microfluidics and chemical engineering can lead to a more complete and comprehensive process. Process Analysis, Design, and Intensification in Microfluidics and Chemical Engineering provides emerging research exploring the theoretical and practical aspects of microfluidics and its application in chemical engineering with the intention of building pathways for new processes and product developments in industrial areas. Featuring coverage on a broad range of topics such as design techniques, hydrodynamics, and numerical modelling, this book is ideally designed for engineers, chemists, microfluidics and chemical engineering companies, academicians, researchers, and students.

Analysis and Design Optimization of Micromixers

Author : Arshad Afzal
Publisher : Springer Nature
ISBN 13 : 9813342919
Total Pages : 74 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Analysis and Design Optimization of Micromixers by : Arshad Afzal

Download or read book Analysis and Design Optimization of Micromixers written by Arshad Afzal and published by Springer Nature. This book was released on 2020-12-07 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the computational framework based on knowledge of flow and mass transfer together with optimization techniques to solve problems relevant to micromixing technology. The authors provide a detailed analysis of the different numerical techniques applied to the design of micromixers. Flow and mixing analysis is based on both the Eulerian and Lagrangian approaches; relative advantages and disadvantages of the two methods and suitability to different types of mixing problems are analysed. The book also discusses the various facets of numerical schemes subjected to discretization errors and computational grid requirements. Since a large number of studies are based on commercial computational fluid dynamics (CFD) packages, relevant details of these packages to the mixing problem using them are presented. Numerical optimization techniques coupled with CFD analysis of flow and mixing have proved to be an important tool for micromixers design, and therefore, are an important part of the book. These techniques are presented briefly, and focus is on surrogate modeling and optimization applied to design of micromixers.

Evaluation of a Microfluidic Mixer Utilizing Staggered Herringbone Channels

Author : Brian A. Hama
Publisher :
ISBN 13 :
Total Pages : 107 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis Evaluation of a Microfluidic Mixer Utilizing Staggered Herringbone Channels by : Brian A. Hama

Download or read book Evaluation of a Microfluidic Mixer Utilizing Staggered Herringbone Channels written by Brian A. Hama and published by . This book was released on 2017 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic platforms offer a variety of advantages including improved heat transfer, low working volumes, ease of scale-up, and strong user control on parameters. However, flow within microfluidic channels occurs at low Reynolds numbers, which makes mixing difficult to accomplish. Adding V-shaped ridges to channel walls, a pattern called the staggered herringbone design (SHB), might alleviate this problem by introducing transverse flow patterns that enable enhanced mixing. However, certain factors affecting the SHB mixer's performance remain largely unexplored.In this work, a microfluidic mixer utilizing the SHB geometry was developed and characterized using computational fluid dynamics based simulations and complimentary experiments. A channel design with SHB ridges was simulated in COMSOL Multiphysics under a variety of operating conditions to evaluate its mixing capabilities. The device was fabricated using soft-lithography to experimentally observe the mixing process. The mixing was visualized by pumping fluorescent dyes through the device and imaging the channels using a confocal microscope.The device was found to efficiently mix fluids rapidly, based on both simulations and experiments. Varying the Reynolds number or component diffusion coefficients had a weak effect on the mixing profile, due to the laminar flow regime and insufficient residence time, respectively. Mixing effectiveness decreased as the component flow rate ratio increased. Fluid flow patterns visualized in confocal microscope images were highly identical to the simulated results, suggesting that the simulations serve as good predictors of the device's performance. This SHB mixer design would be a good candidate for further implementation as a reactor.

Complex Fluid-Flows in Microfluidics

Author : Francisco José Galindo-Rosales
Publisher : Springer
ISBN 13 : 3319595938
Total Pages : 116 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Complex Fluid-Flows in Microfluidics by : Francisco José Galindo-Rosales

Download or read book Complex Fluid-Flows in Microfluidics written by Francisco José Galindo-Rosales and published by Springer. This book was released on 2017-05-26 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph contains expert knowledge on complex fluid-flows in microfluidic devices. The topical spectrum includes, but is not limited to, aspects such as the analysis, experimental characterization, numerical simulations and numerical optimization. The target audience primarily comprises researchers who intend to embark on activities in microfluidics. The book can also be beneficial as supplementary reading in graduate courses.

Microfluidics

Author : Sebastian Seiffert
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110487705
Total Pages : 295 pages
Book Rating : 4.1/5 (14 download)

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Book Synopsis Microfluidics by : Sebastian Seiffert

Download or read book Microfluidics written by Sebastian Seiffert and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-12-02 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics introduces the theory and practice of fluid flow on small scales. The exquisite control of such flow at low Reynolds numbers allows liquids to be processed in either a well-defined co-flow or a well-defined segmented-flow fashion. Both lays a ground for high-throughput analytics and advanced materials design. With that, this book is ideal for research scientists and Ph.D. students in the fields of chemistry, chemical engineering, biotechnology, and materials science.

Microflows and Nanoflows

Author : George Karniadakis
Publisher : Springer Science & Business Media
ISBN 13 : 0387286764
Total Pages : 824 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Microflows and Nanoflows by : George Karniadakis

Download or read book Microflows and Nanoflows written by George Karniadakis and published by Springer Science & Business Media. This book was released on 2006-02-09 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Subject area has witnessed explosive growth during the last decade and the technology is progressing at an astronomical rate. Previous edition was first to focus exclusively on flow physics within microdevices. It sold over 900 copies in North America since 11/01. New edition is 40 percent longer, with four new chapters on recent topics including Nanofluidics.

Fluid Machinery and Fluid Mechanics

Author : Jianzhong Xu
Publisher : Springer Science & Business Media
ISBN 13 : 3540897496
Total Pages : 445 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Fluid Machinery and Fluid Mechanics by : Jianzhong Xu

Download or read book Fluid Machinery and Fluid Mechanics written by Jianzhong Xu and published by Springer Science & Business Media. This book was released on 2010-07-05 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Fluid Machinery and Fluid Mechanics: 4th International Symposium (4th ISFMFE)" is the proceedings of 4th International Symposium on Fluid Machinery and Fluid Engineering, held in Beijing November 24-27, 2008. It contains 69 highly informative technical papers presented at the Mei Lecture session and the technical sessions of the symposium. The Chinese Society of Engineering Thermophysics (CSET) organized the First, the Second and the Third International Symposium on Fluid Machinery and Fluid Engineering (1996, 2000 and 2004). The purpose of the 4th Symposium is to provide a common forum for exchange of scientific and technical information worldwide on fluid machinery and fluid engineering for scientists and engineers. The main subject of this symposium is "Fluid Machinery for Energy Conservation". The "Mei Lecture" reports on the most recent developments of fluid machinery in commemoration of the late professor Mei Zuyan. The book is intended for researchers and engineers in fluid machinery and fluid engineering. Jianzhong Xu is a professor at the Chinese Society of Engineering Thermophysics, Chinese Academy of Sciences, Beijing.

Microfluidics: History, Theory and Applications

Author : William B. J. Zimmerman
Publisher : Springer Science & Business Media
ISBN 13 : 9783211329948
Total Pages : 320 pages
Book Rating : 4.3/5 (299 download)

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Book Synopsis Microfluidics: History, Theory and Applications by : William B. J. Zimmerman

Download or read book Microfluidics: History, Theory and Applications written by William B. J. Zimmerman and published by Springer Science & Business Media. This book was released on 2006-06-27 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics is a microtechnological field dealing with the precise transport of fluids (liquids or gases) in small amounts (e.g. microliters, nanoliters or even picoliters). This book provides a useful introduction into this burgeoning field, and a specific application of microfluidics is presented. It also gives a survey of microfluidics.

Passive Micromixers for DNA Analysis Using CFD Modelling

Author : Ritesh Agarwal
Publisher :
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis Passive Micromixers for DNA Analysis Using CFD Modelling by : Ritesh Agarwal

Download or read book Passive Micromixers for DNA Analysis Using CFD Modelling written by Ritesh Agarwal and published by . This book was released on 2018 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mixing efficiency is an important issue in the design of micromixers, since effective mixing is required between Deoxyribonucleic acid (DNA) sample and restriction enzyme for a fast digestion process. Mixing is improved by chaotic advection through serpentine mixing channels. This leads to the desired reduction in the fluid diffusion path while at the same time increasing the fluid contact areas. The purpose of this research is to evaluate mixing efficiency in microchannel mixers, through a numerical study of different micromixing configuration. To accomplish this, a numerical study is conducted using computational fluid dynamics (CFD) approach using ANSYS Fluent and CFX Software for different geometries designed. Different geometric configuration were proposed and used: bottleneck near the inlet and along the zig zag and curved shaped rectangular zig zag geometry. Mixing analysis is done by different conditions such as Reynold's number, effect of geometry on fluid flow and different diffusion coefficients by evaluating mixing index of the fluid. Results have shown better and faster mixing index around bottleneck region compared to other. This geometry can be used to model passive micromixers and other microfluidic devices with shorter mixing length and for faster mixing between reagents.

Energy for Propulsion

Author : Akshai K. Runchal
Publisher : Springer
ISBN 13 : 9811074739
Total Pages : 499 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Energy for Propulsion by : Akshai K. Runchal

Download or read book Energy for Propulsion written by Akshai K. Runchal and published by Springer. This book was released on 2018-07-06 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research book provides state-of-the-art advances in several areas of energy generation from, and environmental impact of, fuels and biofuels. It also presents novel developments in the areas of biofuels and products from various feedstock materials along with thermal management, emission control and environmental issues. Availability of clean and sustainable energy is of paramount importance in all applications of energy, power, mobility and propulsion. This book is written by internationally renowned experts from around the globe. They provide the latest innovations in cleaner energy utilization for a wide range of devices. The energy and environment sustainability requires a multipronged approach involving development and utilization of new and renewable fuels, design of fuel-flexible combustion systems and novel and environmentally friendly technologies for improved fuel use. This book serves as a good reference for practicing engineers, educators and research professionals.

Computational and Experimental Determination of the Mixing Efficiency of a Microfluidic Serpentine Micromixer

Author : Siril Arockiam
Publisher :
ISBN 13 :
Total Pages : 54 pages
Book Rating : 4.:/5 (124 download)

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Book Synopsis Computational and Experimental Determination of the Mixing Efficiency of a Microfluidic Serpentine Micromixer by : Siril Arockiam

Download or read book Computational and Experimental Determination of the Mixing Efficiency of a Microfluidic Serpentine Micromixer written by Siril Arockiam and published by . This book was released on 2017 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: In microfluidics, efficiency and mixing time are the greatest disadvantages. These parameters hinder the application of microfluidic devices for biochemical and immunological assays. However, once these disadvantages have been overcome by optimizing the parameters of the microfluidic device, it becomes the important analytical tool. In this experiment, various designs of microfluidic devices have been both simulated using COMSOL software, and experimentally verified to obtain the optimized parameter such as depth and velocity for better mixing efficiency. The COMSOL model has been validated by comparing the results with fluorescent images data of the experiment. The microfluidic device is built with Adhesive double-sided tape and glass slides. The microfluidic channels are 25μm in depth and 700μm in width. These channels have a serpentine design with three loops. It was been analyzed that by increasing the depth of the channel to 400μm at 0.1μl/min flow rate, 99.5% mixing efficiency was obtained. As both the contact area and time were increasing, which in turn lead to the increase in diffusion mixing between the two streams.

Analysis and Design Optimization of Micromixers: Conclusion

Author : Arshad Afzal
Publisher :
ISBN 13 : 9789813342934
Total Pages : 65 pages
Book Rating : 4.3/5 (429 download)

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Book Synopsis Analysis and Design Optimization of Micromixers: Conclusion by : Arshad Afzal

Download or read book Analysis and Design Optimization of Micromixers: Conclusion written by Arshad Afzal and published by . This book was released on 2021 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the computational framework based on knowledge of flow and mass transfer together with optimization techniques to solve problems relevant to micromixing technology. The authors provide a detailed analysis of the different numerical techniques applied to the design of micromixers. Flow and mixing analysis is based on both the Eulerian and Lagrangian approaches; relative advantages and disadvantages of the two methods and suitability to different types of mixing problems are analysed. The book also discusses the various facets of numerical schemes subjected to discretization errors and computational grid requirements. Since a large number of studies are based on commercial computational fluid dynamics (CFD) packages, relevant details of these packages to the mixing problem using them are presented. Numerical optimization techniques coupled with CFD analysis of flow and mixing have proved to be an important tool for micromixers design, and therefore, are an important part of the book. These techniques are presented briefly, and focus is on surrogate modeling and optimization applied to design of micromixers.

Computational Fluid Dynamic Analysis and Optimisation of Microfluidic Systems

Author : Hazim Saab Hamad
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (126 download)

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Book Synopsis Computational Fluid Dynamic Analysis and Optimisation of Microfluidic Systems by : Hazim Saab Hamad

Download or read book Computational Fluid Dynamic Analysis and Optimisation of Microfluidic Systems written by Hazim Saab Hamad and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fluid Mechanics for Chemical Engineers with Microfluidics and CFD

Author : James O. Wilkes
Publisher : Prentice Hall
ISBN 13 : 0132441675
Total Pages : 778 pages
Book Rating : 4.1/5 (324 download)

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Book Synopsis Fluid Mechanics for Chemical Engineers with Microfluidics and CFD by : James O. Wilkes

Download or read book Fluid Mechanics for Chemical Engineers with Microfluidics and CFD written by James O. Wilkes and published by Prentice Hall. This book was released on 2005-09-26 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemical Engineer's Practical Guide to Contemporary Fluid Mechanics Since most chemical processing applications are conducted either partially or totally in the fluid phase, chemical engineers need a strong understanding of fluid mechanics. Such knowledge is especially valuable for solving problems in the biochemical, chemical, energy, fermentation, materials, mining, petroleum, pharmaceuticals, polymer, and waste-processing industries. Fluid Mechanics for Chemical Engineers, Second Edition, with Microfluidics and CFD, systematically introduces fluid mechanics from the perspective of the chemical engineer who must understand actual physical behavior and solve real-world problems. Building on a first edition that earned Choice Magazine's Outstanding Academic Title award, this edition has been thoroughly updated to reflect the field's latest advances. This second edition contains extensive new coverage of both microfluidics and computational fluid dynamics, systematically demonstrating CFD through detailed examples using FlowLab and COMSOL Multiphysics. The chapter on turbulence has been extensively revised to address more complex and realistic challenges, including turbulent mixing and recirculating flows. Part I offers a clear, succinct, easy-to-follow introduction to macroscopic fluid mechanics, including physical properties; hydrostatics; basic rate laws for mass, energy, and momentum; and the fundamental principles of flow through pumps, pipes, and other equipment. Part II turns to microscopic fluid mechanics, which covers Differential equations of fluid mechanics Viscous-flow problems, some including polymer processing Laplace's equation, irrotational, and porous-media flows Nearly unidirectional flows, from boundary layers to lubrication, calendering, and thin-film applications Turbulent flows, showing how the k/ε method extends conventional mixing-length theory Bubble motion, two-phase flow, and fluidization Non-Newtonian fluids, including inelastic and viscoelastic fluids Microfluidics and electrokinetic flow effects including electroosmosis, electrophoresis, streaming potentials, and electroosmotic switching Computational fluid mechanics with FlowLab and COMSOL Multiphysics Fluid Mechanics for Chemical Engineers, Second Edition, with Microfluidics and CFD, includes 83 completely worked practical examples, several of which involve FlowLab and COMSOL Multiphysics. There are also 330 end-of-chapter problems of varying complexity, including several from the University of Cambridge chemical engineering examinations. The author covers all the material needed for the fluid mechanics portion of the Professional Engineer's examination. The author's Web site, www.engin.umich.edu/~fmche/, provides additional notes on individual chapters, problem-solving tips, errata, and more.

Dynamics of Droplets

Author : Arnold Frohn
Publisher : Springer Science & Business Media
ISBN 13 : 3662040409
Total Pages : 298 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Dynamics of Droplets by : Arnold Frohn

Download or read book Dynamics of Droplets written by Arnold Frohn and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book deals with the dynamical behaviour of single droplets and regular droplet systems. It has been written mainly for experimental researchers. After a short description of the theoretical background, the different experimental facilities and methods necessary for the investigation of single droplets are described in detail. A summary of important applications is included.

Microfluidics

Author : Bastian E. Rapp
Publisher : Elsevier
ISBN 13 : 0128240229
Total Pages : 848 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Microfluidics by : Bastian E. Rapp

Download or read book Microfluidics written by Bastian E. Rapp and published by Elsevier. This book was released on 2022-09-15 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics: Modeling, Mechanics and Mathematics, Second Edition provides a practical, lab-based approach to nano- and microfluidics, including a wealth of practical techniques, protocols and experiments ready to be put into practice in both research and industrial settings. This practical approach is ideally suited to researchers and R&D staff in industry. Additionally, the interdisciplinary approach to the science of nano- and microfluidics enables readers from a range of different academic disciplines to broaden their understanding. Alongside traditional fluid/transport topics, the book contains a wealth of coverage of materials and manufacturing techniques, chemical modification/surface functionalization, biochemical analysis, and the biosensors involved. This fully updated new edition also includes new sections on viscous flows and centrifugal microfluidics, expanding the types of platforms covered to include centrifugal, capillary and electro kinetic platforms. Provides a practical guide to the successful design and implementation of nano- and microfluidic processes (e.g., biosensing) and equipment (e.g., biosensors, such as diabetes blood glucose sensors) Provides techniques, experiments and protocols that are ready to be put to use in the lab, or in an academic or industry setting Presents a collection of 3D-CAD and image files on a companion website