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Evolving Treatment Paradigms For Renal Cancer
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Book Synopsis Evolving Treatment Paradigms in Renal Cancer, An Issue of Urologic Clinics by : William C. Huang
Download or read book Evolving Treatment Paradigms in Renal Cancer, An Issue of Urologic Clinics written by William C. Huang and published by Elsevier Health Sciences. This book was released on 2012-05-28 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of the Urologic Clinics provides a timely update on Renal Cancer and the evolving treatment standards in urology. Articles include Contemporary Imaging of the Renal Mass, Surgical Approach to Multifocal Renal Cancers, and Systemic Therapy Prior to Surgery. Effects of the various existing surgical approaches on long-term renal function is also discussed, along with a review of the current trends in surgical management of renal cancers with specific attention to utilization of laparoscopic approach, partial nephrectomy, ablative technologies and observation.
Book Synopsis WHO Classification of Tumours of the Urinary System and Male Genital Organs by : International Agency for Research on Cancer
Download or read book WHO Classification of Tumours of the Urinary System and Male Genital Organs written by International Agency for Research on Cancer and published by . This book was released on 2016-02-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Urinary System and Male Genital Organs is the eighth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. It contains numerous color photographs, MRIs, ultrasound images, CT scans, charts and references.
Book Synopsis Renal Cell Carcinoma by : Ronald Bukowski
Download or read book Renal Cell Carcinoma written by Ronald Bukowski and published by Springer Science & Business Media. This book was released on 2009-02-08 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the second edition of their critically acclaimed book, Ronald Bukowski, Robert Motzer, and Robert Figlin have thoroughly updated and expanded their survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. A panel of internationally renowned contributors explores the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. The discussion includes the specific biology of selected target molecules or receptors and the various agents that inhibit these targets, including full chapters devoted to drugs that selectively inhibit receptor tyrosine kinases, such as sunitinib and axitinib. Further attention is paid to leading-edge strategies that target and inhibit tumor associated angiogenesis and block the vascular endothelial growth factor pathway. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Second Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by the pioneers of the field.
Book Synopsis High Dose Chemotherapy by : Paul C. Lorigan
Download or read book High Dose Chemotherapy written by Paul C. Lorigan and published by CRC Press. This book was released on 2002-04-11 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents an overview of the basic science and principles of high dose chemotherapy, current state-of-the-art techniques and future developments such as gene therapy. The main section of the book is disease-based, setting the scientific principles within a clinical context and reviewing the application of high dose therapy in specific diseases. Additional sections discuss supportive care and long-term complications. High Dose Chemotherapy is directed at hematologists, clinical and medical oncologists in training or with an interest, rather than direct involvement, in the field.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309457971 Total Pages :145 pages Book Rating :4.3/5 (94 download)
Book Synopsis The Drug Development Paradigm in Oncology by : National Academies of Sciences, Engineering, and Medicine
Download or read book The Drug Development Paradigm in Oncology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-02-12 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.
Book Synopsis Evolving Treatment Paradigms for Renal Cancer by :
Download or read book Evolving Treatment Paradigms for Renal Cancer written by and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Changing Paradigms in Breast Cancer Diagnosis and Treatment, An Issue of Surgical Oncology Clinics of North America, E-Book by : Kelly K. Hunt
Download or read book Changing Paradigms in Breast Cancer Diagnosis and Treatment, An Issue of Surgical Oncology Clinics of North America, E-Book written by Kelly K. Hunt and published by Elsevier Health Sciences. This book was released on 2017-11-21 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Kelly Hunt, is devoted to Changing Paradigms in Breast Cancer Diagnosis and Treatment. Dr. Hunt has assembled expert authors to review the following topics: Tomosynthesis in breast cancer imaging: how does it fit into preoperative evaluation and surveillance?; Lobular breast cancer: different disease, different algorithms?; Hypofractionated radiation therapy in breast conserving therapy; Oncoplastic breast reconstruction: should all patients be considered?; Neoadjuvant endocrine therapy: who benefits most?; Breast cancer disparities: how can we leverage genomics to improve outcomes?; Anatomy and breast cancer staging: is it still relevant?; When does atypical ductal hyperplasia require surgical intervention?; Surgical intervention for lymphedema; Are there alternative strategies in the local management of DCIS?; Genetic testing and genetic counseling: what is standard of care?; Molecular subtypes and local-regional control of breast cancer; Intraoperative margin assessment in breast cancer management; Triple negative breast cancer: who should receive neoadjuvant chemotherapy?; and more!
Book Synopsis Rare Genitourinary Tumors by : Lance Pagliaro
Download or read book Rare Genitourinary Tumors written by Lance Pagliaro and published by Springer. This book was released on 2018-06-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rare Genitourinary Tumors offers the reader an up-to-date discussion of the less common neoplasms affecting the urinary tract and reproductive organs. Each authoritative chapter provides and in-depth discussion that is frequently not found in other urologic oncology textbooks. A valuable reference for urologists, oncologists, and those in specialty training, this volume provides ready access to information on etiology, incidence, risk factors, diagnosis, prognosis, insights from molecular pathology and, where applicable, data from clinical trials. The practical treatment guidelines included for each tumor type are written by experts and fully referenced.
Download or read book Renal Cancer written by John A. Libertino and published by Springer Nature. This book was released on 2019-10-16 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated second edition provides a comprehensive, state of the art review of renal cancer, and will serve as a guide for urology residents, clinicians, surgeons, and researchers with an interest in renal cell carcinoma. The title reviews the latest information regarding epidemiology, clinical staging, molecular biology and genetics, hereditary syndromes, pathology, imaging, molecular imaging, interventional radiology, surgical advances, and the unified approach to surgery and systemic therapy of renal cell carcinoma. It also addresses the management of localized RCC, locally advanced disease, and advanced disease. A valuable resource for physicians and researchers dealing with renal cancer, Renal Cancer: Contemporary Management, Second Edition provides a comprehensive summary of the field that will guide patient management and stimulate further clinical and basic science research efforts.
Download or read book Cancer written by Vincent T. DeVita and published by Lippincott Williams & Wilkins. This book was released on 2010 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing the first volume of a new series, Cancer: Principles & Practice of Oncology—Annual Advances in Oncology. This series of annual volumes will focus on the most significant changes in oncologic research and practice that have taken place during the preceding year. Each volume identifies scientific and clinical areas in oncology that are rapidly changing and show a high potential for affecting the management of cancer patients in the future. These areas may reflect current controversies in oncology and every effort is made to provide clear direction for the practicing oncologist.
Book Synopsis Establishment of marker models for molecular typing of renal cell carcinoma by : Linhui Wang
Download or read book Establishment of marker models for molecular typing of renal cell carcinoma written by Linhui Wang and published by Frontiers Media SA. This book was released on 2023-07-31 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Evolving Trends in Kidney Cancer by : Sashi S. Kommu
Download or read book Evolving Trends in Kidney Cancer written by Sashi S. Kommu and published by BoD – Books on Demand. This book was released on 2020-07-22 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney cancer imposes a significant cancer burden and its incidence continues to rise globally. Mortality in advanced kidney cancer remains high despite oncological, surgical and multimodal optimisation. Genetic associations, heterogeneity and limitations in early diagnosis through lack of optimal biomarkers add to the challenges. Over the last two decades there has been an exponential increase in diagnostic and therapeutic advances in the management of kidney cancer. The coupling of scientific advances in engineering and technology with oncological therapeutics has recently ushered a renewed optimism. The role of minimally invasive approaches through focal therapy and surgical extirpation using the robotic platform has been unprecedented and paramount. Virtual augmentation and mixed reality platforms have proved useful supplementary tools in surgical planning. The role of surgical simulation and training in development of surgeons with the optimal skill set is essential to provide optimal care. This book is the first in a series that explores the evolving trends in kidney cancer. The focus of the book is broad and includes topics ranging from immunotherapy to surgical simulation. Some chapters explore leading edge concepts while others capture the evolving trends and future concepts. The Editors aim to stimulate the readers to explore the key concepts and to encourage research and innovation along the main themes presented.
Book Synopsis Changing Paradigm in Breast Cancer Management by : Mehta Ajay
Download or read book Changing Paradigm in Breast Cancer Management written by Mehta Ajay and published by JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.. This book was released on 2011-02-28 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fast pace moving world of change in science and technology, this book describes the changing faces in medical practice in management of breast cancer. 50s was the era of "Clinical Sciences" based on anatomicopathologic data and good clinical medicine. The 60s-70s was the era of "Technological Sciences" based on imaging and instrumentations. The 80s-90s was the era of "Biological Sciences-Molecular Biology, Molecular Genetics, based on laboratory medicine-Beyond Morphology. The text begins with epidemiology and screening of breast cancer, followed by early detection of breast cancer, TN.
Book Synopsis Precision Medicine in Oncology by : Angela Re
Download or read book Precision Medicine in Oncology written by Angela Re and published by Frontiers Media SA. This book was released on 2019-01-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emerging precision medicine approach aims to tailor disease prevention and treatment to each patient on the basis of individual variability, environmental factors and lifestyle. Fundamental achievements in the last few decades have converged to offer nowadays the compelling opportunity to move towards this innovative approach: i) unprecedented improvements in disease modeling in silico, in vitro and in vivo; ii) acquisition of a wide range of biomedical information combined with the development of computational toolsets for flexible and integrative analyses of multi-assay datasets. Our deeper understanding of oncogenic mechanisms has finally begun to have a crucial impact on clinical decisions at several steps, from cancer prevention and diagnosis to therapeutic intervention. However, precision oncology still encounters several unresolved hurdles including tumour heterogeneity and recurrence as well as unexplained drug resistance and lack of effective ways to monitor response to therapeutic treatments. Notably, limitations in biomedical research regulation and governance represent additional debatable issues that need careful consideration.
Book Synopsis Diagnosis and Surgical Management of Renal Tumors by : Michael A. Gorin
Download or read book Diagnosis and Surgical Management of Renal Tumors written by Michael A. Gorin and published by Springer. This book was released on 2018-11-09 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renal cell carcinoma (RCC) is the most common primary malignancy of the kidney, with an estimated 64,000 new cases diagnosed each year in the United States. Worldwide, this figure approaches 270,000 annual incident cases. At the time of initial presentation, 80% of patients with RCC will be diagnosed with a tumor localized the kidney. The majority of these lesions will be small (i.e. ≤4 cm) and potentially curable with either partial or radical nephrectomy. In recent decades, the rate of incidentally detected small renal tumors has risen substantially due the increasing use of cross-sectional imaging performed across the field of medicine. This rise in the incident number of localized renal tumors has unfortunately not resulted in a corresponding decrease in cases of metastatic RCC. This observation has led to our understanding that a significant proportion of incidentally detected renal tumors are of low malignant potential and may be safely managed with alternatives to surgery such active surveillance and thermo ablation. The use of these less invasive management approaches, however, must be balanced by the reality that upon spreading beyond the confines of the kidney, RCC is almost always incurable. Thus, when selecting a management strategy for a given patient, one must employ a risk-adapted approach that includes knowledge of a tumor’s histology and metastatic potential. In each patient, the goal of management should be to minimize the risk of progression to metastatic disease while preserving renal function and minimizing morbidity. This text provides a contemporary review of the diagnosis and surgical management of RCC. It opens with chapters on the pathology, radiology, and genetics of RCC. It then covers the risk stratification of renal tumors utilizing renal mass biopsy as well as non-invasive novel imaging-based scoring systems. Next, the surgical management of small and locally advanced renal tumors as well as the role of surgery in cases of metastatic RCC is reviewed. In addition, alternative approaches to surgery including active surveillance and ablative techniques are reviewed. Other chapters detail the emerging role of neoadjuvant and adjuvant systemic therapy in patients who are at high risk of progression to metastatic disease. Finally, the text covers the post-operative surveillance of patients with RCC as well as a summary of contemporary guidelines on the management of this disease. Diagnosis and Surgical Management of Renal Cell Carcinoma will serve as a comprehensive resource for physicians and researchers interested in RCC. All chapters will be written by experts in the field and will include the most up to date scientific and clinical information.
Book Synopsis Understanding Pathophysiology Australia and New Zealand Edition by : Judy Craft
Download or read book Understanding Pathophysiology Australia and New Zealand Edition written by Judy Craft and published by Elsevier Health Sciences. This book was released on 2022-10-15 with total page 1436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Pathophysiology Australia and New Zealand Edition
Book Synopsis Online Adaptive MR-guided Radiotherapy by : Linda G. W. Kerkmeijer
Download or read book Online Adaptive MR-guided Radiotherapy written by Linda G. W. Kerkmeijer and published by Frontiers Media SA. This book was released on 2021-10-18 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
