Evolution vers une médecine personnalisée de la prise en charge thérapeutique du cancer du sein

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Publisher :
ISBN 13 :
Total Pages : 125 pages
Book Rating : 4.:/5 (869 download)

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Book Synopsis Evolution vers une médecine personnalisée de la prise en charge thérapeutique du cancer du sein by : Paul Vilquin

Download or read book Evolution vers une médecine personnalisée de la prise en charge thérapeutique du cancer du sein written by Paul Vilquin and published by . This book was released on 2013 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Le cancer du sein est classiquement réparti selon des critères anatomo-pathologiques en trois sous-types majeurs: hormona-dépendant, Human Epidermal Growth Factor Receptor-2 positif et triple négatif. Le développement récent des technologies à haut débit a permis de mieux appréhender l'hétérogénéité du cancer du sein en révélant l'existence d'une multitude d'entités moléculaires au sein de ces trois sous-types. Malgré l'enthousiasme généré autour des thérapies ciblées, l'efficacité clinique de ces molécules demeure encore limitée. Une des approches actuelles pour surmonter ce problème est de mieux sélectionner les patientes pouvant bénéficier d'une thérapie ciblée donnée en se basant sur les données moléculaires de chaque patiente. Cette personnalisation de la prise en charge des patientes va très prochainement modifier en profondeur la façon de développer et d'évaluer les nouvelles molécules. L'émergence de la médecine personnalisée constitue donc un véritable défi nécessitant une coordination multi-disciplinaire englobant des compétences scientifiques, pharmaceutiques et médicales multiples pour sa mise en place en pratique clinique

Traitement personnalisé des cancers du sein : impact sur la prise en charge loco-régionale

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Publisher : Springer
ISBN 13 : 9782817804941
Total Pages : 400 pages
Book Rating : 4.8/5 (49 download)

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Book Synopsis Traitement personnalisé des cancers du sein : impact sur la prise en charge loco-régionale by : Anne Lesur

Download or read book Traitement personnalisé des cancers du sein : impact sur la prise en charge loco-régionale written by Anne Lesur and published by Springer. This book was released on 2013-11-18 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: La personnalisation de la prise en charge des cancers est un des challenges de la cancérologie moderne. Tout le monde y fait référence mais qui l’applique ? Depuis toujours, les sénologues appréhendent au travers de l’examen clinique, la multiplicité des formes diagnostiques des cancers du sein. Le dépistage et le diagnostic précoce ont augmenté l’incidence des tumeurs classiquement étiquetées de “bon pronostic”. L’imagerie, l’anatomopathologie, la biologie, la génomique ont permis de faire exploser l’entité cancer du sein en autant de sous-groupes pronostiques. Alors que le terme de personnalisation reste à définir dans ses multiples approches, il faut se poser les questions de sa place dans les référentiels existants, de la démonstration méthodologique de son efficience hors essais cliniques traditionnels, du rôle du processus décisionnel dans son application. Quand la science n’apporte pas suffisamment de certitude, y a-t-il une place pour faire participer la patiente au processus décisionnel ? Dans cet ouvrage, l’aspect loco-régional sera “disséqué” pour remettre en questions certains dogmes, poser de nouvelles questions et nous l’espérons apporter des réponses.

Adjuvant Therapy for Breast Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 0387751157
Total Pages : 483 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Adjuvant Therapy for Breast Cancer by : Monica Castiglione

Download or read book Adjuvant Therapy for Breast Cancer written by Monica Castiglione and published by Springer Science & Business Media. This book was released on 2009-07-11 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.

Clinical Pediatric Oncology

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Publisher :
ISBN 13 :
Total Pages : 982 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Clinical Pediatric Oncology by : Wataru Walter Sutow

Download or read book Clinical Pediatric Oncology written by Wataru Walter Sutow and published by . This book was released on 1984 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Managing Breast Cancer Risk

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Publisher : PMPH-USA
ISBN 13 : 9781550092608
Total Pages : 328 pages
Book Rating : 4.0/5 (926 download)

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Book Synopsis Managing Breast Cancer Risk by : Monica Morrow

Download or read book Managing Breast Cancer Risk written by Monica Morrow and published by PMPH-USA. This book was released on 2003 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing Breast Cancer Risk is a single source for information needed by primary care physicians, nurses, gynecologists, as well as oncologic specialists who deal with women who are concerned about breast cancer. Its purpose is to bring together a multidisciplinary group of experts to address breast cancer risk in a clinically meaningful way. Chapters providing detailed information on individual risk factors are accompanied by a discussion of models, which integrate multiple factors for a more complete assessment of risk. Traditional strategies for risk management, including surveillance and prophylactic surgery, are reviewed, and the data on newer techniques such as ductal lavage and screening with magnetic resonance is presented. The rational for chemoprevention with selective estrogen receptor modulators (SERMS) is discussed, and the evidence for tamoxifen as a chemopreventative is updated. The potential for chemoprevention with newer SERMS and the aromatase inhibitors is reviewed. Finally, the critical (and often ignored) areas of quality of life and symptom management are addressed.

Cancer on Trial

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Publisher : University of Chicago Press
ISBN 13 : 022614304X
Total Pages : 475 pages
Book Rating : 4.2/5 (261 download)

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Book Synopsis Cancer on Trial by : Peter Keating

Download or read book Cancer on Trial written by Peter Keating and published by University of Chicago Press. This book was released on 2014-04-18 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: There were no medical oncologists until a few decades ago. In the early 1960s, not only were there no such specialists, many practitioners regarded the treatment of terminally-ill cancer patients with heroic courses of chemotherapy as highly questionable. Physicians loath to assign patients randomly to competing treatments also expressed their outright opposition to the randomized clinical trials that were then relatively rare. And yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology move from a non-entity and in some regards a reviled practice to the central position it now occupies in modern medicine? Cancer on Trial answers these questions by exploring how practitioners established a new style of practice, at the center of which lies the cancer clinical trial.

Androgen Deprivation Therapy

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Publisher : Springer Publishing Company
ISBN 13 : 0826183956
Total Pages : 247 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Androgen Deprivation Therapy by : Richard J. Wassersug, PhD

Download or read book Androgen Deprivation Therapy written by Richard J. Wassersug, PhD and published by Springer Publishing Company. This book was released on 2021-07-12 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for Androgen Deprivation Therapy: "To my knowledge [this] is the only book written in plain language (no medical jargon) explaining what’s happening during ADT, and detailing how to limit and often solve most associated side effects. It should be read by every man undergoing ADT, as well as family members and also healthcare providers. They will find all the details they need to get the most from this treatment..." Prof. N. Mottet, MD, PhD, Urologist, Medical Oncologist, Head of the Prostate Cancer Guidelines panel of the European Association of Urology Androgen Deprivation Therapy is the only guide written exclusively about the side effects of hormone therapy. The authors have collaborated with the European Association of Urology to produce this specially revised new edition to serve men affected by ADT across the globe. This comprehensive workbook for prostate cancer patients and their loved ones is filled with practical advice from experts in the field. The book covers a wealth of strategies to help men cope with ADT and maintain a good quality of life while on this treatment. It is not only an informational manual, but a guide for both patients and partners about ways to make changes in their lives that can keep them healthy and positive when the patient is on ADT. New to this Edition: Updates on the physical side effects of ADT and management strategies Expanded information on exercise and nutrition for men diagnosed with prostate cancer Updates on the primary drugs used to treat prostate cancer and extensive drug tables with common brand names worldwide Revisions throughout based on critical feedback from international medical experts in the field of prostate cancer and related disciplines Exercises, activities, worksheets, and other tools to promote discussion and inspire behavioural changes that can reduce the burden of ADT Officially endorsed by the European Association of Urology

Comprehensive Cervical Cancer Control

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Publisher : World Health Organization
ISBN 13 : 9241547006
Total Pages : 284 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Comprehensive Cervical Cancer Control by : World Health Organization

Download or read book Comprehensive Cervical Cancer Control written by World Health Organization and published by World Health Organization. This book was released on 2006 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most women who die from cervical cancer, particularly in developing countries, are in the prime of their life. They may be raising children, caring for their family, and contributing to the social and economic life of their town or village. Their death is both a personal tragedy, and a sad and unnecessary loss to their family and their community. Unnecessary, because there is compelling evidence, as this Guide makes clear, that cervical cancer is one of the most preventable and treatable forms of cancer, as long as it is detected early and managed effectively. Unfortunately, the majority of women in developing countries still do not have access to cervical cancer prevention programmes. The consequence is that, often, cervical cancer is not detected until it is too late to be cured. An urgent effort is required if this situation is to be corrected. This Guide is intended to help those responsible for providing services aimed at reducing the burden posed by cervical cancer for women, communities and health systems. It focuses on the knowledge and skills needed by health care providers, at different levels of care.

Ethics of Big Data

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Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1449357490
Total Pages : 80 pages
Book Rating : 4.4/5 (493 download)

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Book Synopsis Ethics of Big Data by : Kord Davis

Download or read book Ethics of Big Data written by Kord Davis and published by "O'Reilly Media, Inc.". This book was released on 2012-09-13 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are your organization’s policies for generating and using huge datasets full of personal information? This book examines ethical questions raised by the big data phenomenon, and explains why enterprises need to reconsider business decisions concerning privacy and identity. Authors Kord Davis and Doug Patterson provide methods and techniques to help your business engage in a transparent and productive ethical inquiry into your current data practices. Both individuals and organizations have legitimate interests in understanding how data is handled. Your use of data can directly affect brand quality and revenue—as Target, Apple, Netflix, and dozens of other companies have discovered. With this book, you’ll learn how to align your actions with explicit company values and preserve the trust of customers, partners, and stakeholders. Review your data-handling practices and examine whether they reflect core organizational values Express coherent and consistent positions on your organization’s use of big data Define tactical plans to close gaps between values and practices—and discover how to maintain alignment as conditions change over time Maintain a balance between the benefits of innovation and the risks of unintended consequences

Global Burden of Disease and Risk Factors

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Publisher : World Bank Publications
ISBN 13 : 0821362631
Total Pages : 511 pages
Book Rating : 4.8/5 (213 download)

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Book Synopsis Global Burden of Disease and Risk Factors by : Alan D. Lopez

Download or read book Global Burden of Disease and Risk Factors written by Alan D. Lopez and published by World Bank Publications. This book was released on 2006-04-02 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.

Innovate Bristol

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Publisher :
ISBN 13 : 9781949677072
Total Pages : pages
Book Rating : 4.6/5 (77 download)

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Book Synopsis Innovate Bristol by : Sven Boermeester

Download or read book Innovate Bristol written by Sven Boermeester and published by . This book was released on 2019-12 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovate Bristol highlights and celebrates those companies and individuals that are actively working at building a better tomorrow for all. Innovation Ecosystems thrive through the involvement and support of companies and individuals from all industries, which is why the Innovate series not only focuses on the innovators but also those people whom the Innovation Ecosystem, would not be able to thrive without.

Comprehensive Geriatric Assessment

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Publisher : Springer
ISBN 13 : 3319625039
Total Pages : 182 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Comprehensive Geriatric Assessment by : Alberto Pilotto

Download or read book Comprehensive Geriatric Assessment written by Alberto Pilotto and published by Springer. This book was released on 2017-12-29 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an up-to-date review on the principles and practice of multidimensional assessment and management of the older individual, which represents the cornerstone of modern clinical practice in the elderly. The early chapters cover the main elements and scope of the comprehensive geriatric approach and explain the pathways of care from screening and case finding through to in-depth assessment and treatment planning. Subsequent chapters review the evidence of how best to apply the multidimensional assessment and management approach in defined healthcare settings and within specific clinical areas, such as cancer and surgery. Finally, the education and training challenges are reviewed and the prospects for future clinical service and research in this important field are examined. The book is very timely given the recent advances in application of this approach, which reflect the growing international realization that older people are “core business” in many clinical areas where the role of specialist geriatric medicine has hitherto been limited. Accordingly, the book will be relevant to a wide range of clinicians. The authorship comprises many of the best known and widely published experts in their respective fields.

The Patient Will See You Now

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Publisher : Basic Books
ISBN 13 : 0465094473
Total Pages : 386 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis The Patient Will See You Now by : Eric Topol

Download or read book The Patient Will See You Now written by Eric Topol and published by Basic Books. This book was released on 2016-10-25 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential guide by one of America's leading doctors to how digital technology enables all of us to take charge of our health A trip to the doctor is almost a guarantee of misery. You'll make an appointment months in advance. You'll probably wait for several hours until you hear "the doctor will see you now"-but only for fifteen minutes! Then you'll wait even longer for lab tests, the results of which you'll likely never see, unless they indicate further (and more invasive) tests, most of which will probably prove unnecessary (much like physicals themselves). And your bill will be astronomical. In The Patient Will See You Now, Eric Topol, one of the nation's top physicians, shows why medicine does not have to be that way. Instead, you could use your smartphone to get rapid test results from one drop of blood, monitor your vital signs both day and night, and use an artificially intelligent algorithm to receive a diagnosis without having to see a doctor, all at a small fraction of the cost imposed by our modern healthcare system. The change is powered by what Topol calls medicine's "Gutenberg moment." Much as the printing press took learning out of the hands of a priestly class, the mobile internet is doing the same for medicine, giving us unprecedented control over our healthcare. With smartphones in hand, we are no longer beholden to an impersonal and paternalistic system in which "doctor knows best." Medicine has been digitized, Topol argues; now it will be democratized. Computers will replace physicians for many diagnostic tasks, citizen science will give rise to citizen medicine, and enormous data sets will give us new means to attack conditions that have long been incurable. Massive, open, online medicine, where diagnostics are done by Facebook-like comparisons of medical profiles, will enable real-time, real-world research on massive populations. There's no doubt the path forward will be complicated: the medical establishment will resist these changes, and digitized medicine inevitably raises serious issues surrounding privacy. Nevertheless, the result-better, cheaper, and more human health care-will be worth it. Provocative and engrossing, The Patient Will See You Now is essential reading for anyone who thinks they deserve better health care. That is, for all of us.

Tele-oncology

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Publisher : Springer
ISBN 13 : 3319163787
Total Pages : 91 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Tele-oncology by : Giovanna Gatti

Download or read book Tele-oncology written by Giovanna Gatti and published by Springer. This book was released on 2015-06-09 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how telemedicine can offer solutions capable of improving the care and survival rates of cancer patients and can also help patients to live a normal life in spite of their condition. Different fields of application – community, hospital and home based – are examined, and detailed attention is paid to the use of tele-oncology in rural/extreme rural settings and in developing countries. The impact of new technologies and the opportunities afforded by the social web are both discussed. The concluding chapters consider eLearning in relation to cancer care and assess the scope for education to improve prevention. No medical condition can shatter people’s lives as cancer does today and the need to develop strategies to reduce the disease burden and improve quality of life is paramount. Readers will find this new volume in Springer’s TELe Health series to be a rich source of information on the important contribution that can be made by telemedicine in achieving these goals.

Focal Therapy in Prostate Cancer

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Publisher : John Wiley & Sons
ISBN 13 : 1405196491
Total Pages : 213 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Focal Therapy in Prostate Cancer by : Hashim Uddin Ahmed

Download or read book Focal Therapy in Prostate Cancer written by Hashim Uddin Ahmed and published by John Wiley & Sons. This book was released on 2011-12-27 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation. Bringing together eminent contributors in one accessible reference, this book introduces focal therapy to all urologists, oncologists, and radiologists who are involved in the treatment of men with prostate cancer.

The Patient's Brain

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Publisher : Oxford University Press
ISBN 13 : 0199579512
Total Pages : 303 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis The Patient's Brain by : Fabrizio Benedetti

Download or read book The Patient's Brain written by Fabrizio Benedetti and published by Oxford University Press. This book was released on 2011 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to advances within neuroscience, we are now in a much better position to be able to describe and discuss the biological mechanisms that underlie the doctor-patient relationship. Using this knowlege, this book describes and demonstrates the power that the doctor's behaviour has on a patient's behaviour and capacity for recovery from illness.

Integrative Neuroscience and Personalized Medicine

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Publisher : Oxford University Press
ISBN 13 : 0195393805
Total Pages : 346 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Integrative Neuroscience and Personalized Medicine by : Evian Gordon

Download or read book Integrative Neuroscience and Personalized Medicine written by Evian Gordon and published by Oxford University Press. This book was released on 2011 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.