Evidence-Based Clinical Chelation

Download Evidence-Based Clinical Chelation PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 3750428670
Total Pages : 122 pages
Book Rating : 4.7/5 (54 download)

DOWNLOAD NOW!


Book Synopsis Evidence-Based Clinical Chelation by : Dr. Eleonore Blaurock-Busch, PhD

Download or read book Evidence-Based Clinical Chelation written by Dr. Eleonore Blaurock-Busch, PhD and published by BoD – Books on Demand. This book was released on 2020-06-02 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an easy-to-read manual about chelation therapy. It contains specific protocols for the treatment of chronic metal overexposure, all of which are evidence-based, aiding the inexperienced and the experienced therapist in selecting the optimal chelating agent for the metal(s) in question. Expert chemists and chelation therapists have contributed invaluable knowledge and experience to this book. Most importantly, this is not a book promoting personal views or preferences. In fact, the information presents and explains different approaches, and allows the reader to draw his own conclusion. All the protocols listed have been modified for the treatment of chronic metal intoxication, included are oral and intravenous treatment plans. The authors explain in simple terms how a chelating agent ́s bioavailability affects metal binding and how various protocols such as the Cutler Protocol affect the detoxification process, why DMPS binds mercury and which chelators are useful for the detoxification of certain organ system. Also discussed is the importance and effect of treatment pauses. Diagnostic tests are discussed, and which are useful under certain conditions. Shown are tables comparing the average metal binding ability of the various EDTAs, DMPS, DMSA and other chelating agents. Detailed information explains which chelator binds which metal and why, all of which aids the therapist in finding optimal treatment schedules. Novel chelating agents are presented such as MIADMSA, a new oral chelator specifically designed for arsenic intoxication, or how natural Pectin may be used an alternative for gadolinium intoxication, which metals are bound by lipoic acid and why a slightly alkaline environment supports metal binding, even preventing the often-feared metal redistribution. All in all, this evidence-based chelation "cookbook" should be in medical libraries and on the bookshelf of every physician treating environmental disease.

Chelation Therapy in the Treatment of Metal Intoxication

Download Chelation Therapy in the Treatment of Metal Intoxication PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128030739
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Chelation Therapy in the Treatment of Metal Intoxication by : Jan Aaseth

Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). Presents all the current findings on the potential for chelation as a therapy for metal intoxication Presents practical guidelines for selecting the most appropriate chelating agent Includes coverage on radionuclide exposure and metal storage diseases Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

A Textbook on EDTA Chelation Therapy

Download A Textbook on EDTA Chelation Therapy PDF Online Free

Author :
Publisher : Hampton Roads Publishing
ISBN 13 : 1612832741
Total Pages : 527 pages
Book Rating : 4.6/5 (128 download)

DOWNLOAD NOW!


Book Synopsis A Textbook on EDTA Chelation Therapy by : Elmer M. Cranton

Download or read book A Textbook on EDTA Chelation Therapy written by Elmer M. Cranton and published by Hampton Roads Publishing. This book was released on 2001-04-01 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation therapy, based on the intravenous infusion of EDTA, is a highly effective treatment for atherosclerotic cardiovasular disease. Saftey and effectivenss are well documented in clinical studies, all of which to date are supportive of this therapy, and there are no studies showing lack of effectiveness. A strong case is made for the use of this safe, efficacious, and inexpensive therapy before resorting to surgery and other risky and invasive treatments. In this newly revised and extensively updated edition of what has come to be regarded as the definitive textbook on the subject, renowned chelation expert Elmer M. Cranton, M.D., presents the work of the world's leading experts in chelation therapy. "This therapy has been proven effective over and over again in clinical practice," says Dr. Cranton. "More than one million patients have recieved more than twenty million infusions with no serious or lasting adverse effects." In his foreword, Nobel Prize winner Dr. Linus Pauling states, "EDTA chelation therapy makes good sense to me as a chemist and medical researcher. It has a rational scientific basis, and the evidence for clinical benefit seems to be quite strong." Here in a single volume you will learn everything you need to know to responsibly administer and advocate chelation therapy. You will find a coherent scientific rationale, clinical trials demonstating effectiveness, guidelines for saftey, detailed protocols for administration, and techniques for pre- and post-treatment laboratory evalutaion.

Iron Chelation Therapy

Download Iron Chelation Therapy PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461505933
Total Pages : 275 pages
Book Rating : 4.4/5 (615 download)

DOWNLOAD NOW!


Book Synopsis Iron Chelation Therapy by : Chaim Hershko

Download or read book Iron Chelation Therapy written by Chaim Hershko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

Handbook of Arsenic Toxicology

Download Handbook of Arsenic Toxicology PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0323984711
Total Pages : 988 pages
Book Rating : 4.3/5 (239 download)

DOWNLOAD NOW!


Book Synopsis Handbook of Arsenic Toxicology by : Swaran Jeet Singh Flora

Download or read book Handbook of Arsenic Toxicology written by Swaran Jeet Singh Flora and published by Academic Press. This book was released on 2023-02-21 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology. This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need to know on arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasures

Hepatotoxicity

Download Hepatotoxicity PDF Online Free

Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 848 pages
Book Rating : 4.7/5 (195 download)

DOWNLOAD NOW!


Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Guidelines for the Clinical Management of Thalassaemia

Download Guidelines for the Clinical Management of Thalassaemia PDF Online Free

Author :
Publisher :
ISBN 13 : 9789963623709
Total Pages : pages
Book Rating : 4.6/5 (237 download)

DOWNLOAD NOW!


Book Synopsis Guidelines for the Clinical Management of Thalassaemia by : Maria-Domenica Cappellini

Download or read book Guidelines for the Clinical Management of Thalassaemia written by Maria-Domenica Cappellini and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Practice in Clinical Chemistry

Download Contemporary Practice in Clinical Chemistry PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128158336
Total Pages : 1070 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Contemporary Practice in Clinical Chemistry by : William Clarke

Download or read book Contemporary Practice in Clinical Chemistry written by William Clarke and published by Academic Press. This book was released on 2020-06-11 with total page 1070 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry. Includes enhanced illustration and new and revised color figures Provides improved self-assessment questions and end-of-chapter assessment questions

An Evidence-based Clinical Textbook in Obstetrics & Gynecology for MRCOG-2

Download An Evidence-based Clinical Textbook in Obstetrics & Gynecology for MRCOG-2 PDF Online Free

Author :
Publisher : JP Medical Ltd
ISBN 13 : 9386322870
Total Pages : 918 pages
Book Rating : 4.3/5 (863 download)

DOWNLOAD NOW!


Book Synopsis An Evidence-based Clinical Textbook in Obstetrics & Gynecology for MRCOG-2 by : Richa Saxena

Download or read book An Evidence-based Clinical Textbook in Obstetrics & Gynecology for MRCOG-2 written by Richa Saxena and published by JP Medical Ltd. This book was released on 2017-04-30 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical guide to obstetrics and gynaecology for trainees preparing for the MRCOG Part 2 examination. Beginning with a brief overview of general principles, the rest of the book is clearing set into two sections – Obstetrics, and Gynaecology. Each of these sections is further divided to discuss the diagnosis and management of numerous disorders within each sub-specialty. The book has been written in accordance with the current MRCOG Part 2 curriculum and includes the very latest RCOG Green-top guidelines and NICE guidelines. Additionally, this comprehensive textbook features the latest statistics on maternal and perinatal mortality in the UK, published by MBRRACE-UK in December 2016. Key Points Practical guide to obstetrics and gynaecology for MRCOG Part 2 candidates Written in accordance with current MRCOG Part 2 curriculum Includes latest RCOG Green-top guidelines and NICE guidelines Features latest statistics on maternal and perinatal mortality from MBRRACE-UK

Lead Toxicity

Download Lead Toxicity PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 60 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Lead Toxicity by : Sarah E. Royce

Download or read book Lead Toxicity written by Sarah E. Royce and published by . This book was released on 2000 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug-Induced Liver Disease

Download Drug-Induced Liver Disease PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 0203909127
Total Pages : 790 pages
Book Rating : 4.2/5 (39 download)

DOWNLOAD NOW!


Book Synopsis Drug-Induced Liver Disease by : Neil Kaplowitz

Download or read book Drug-Induced Liver Disease written by Neil Kaplowitz and published by CRC Press. This book was released on 2002-10-16 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.

Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose

Download Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose PDF Online Free

Author :
Publisher : Saunders
ISBN 13 : 9780721606934
Total Pages : 0 pages
Book Rating : 4.6/5 (69 download)

DOWNLOAD NOW!


Book Synopsis Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose by : Michael W. Shannon

Download or read book Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose written by Michael W. Shannon and published by Saunders. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition is a reference for information related to the clinical management of children and adults whose health has been effected or potentially effected by toxic agents, including drugs, environmental threats, and natural toxins.

Research Skills for Medical Students

Download Research Skills for Medical Students PDF Online Free

Author :
Publisher : SAGE
ISBN 13 : 0857256033
Total Pages : 266 pages
Book Rating : 4.8/5 (572 download)

DOWNLOAD NOW!


Book Synopsis Research Skills for Medical Students by : Ann K. Allen

Download or read book Research Skills for Medical Students written by Ann K. Allen and published by SAGE. This book was released on 2012-07-18 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised Tomorrow′s Doctors makes it clear that doctors need to be aware of their responsibilities as scholars and scientists and it is therefore vital that students develop excellent research skills. Whilst there are many ′research skills′ books, medical students frequently struggle with understanding the difference between the practices of research, audit, service evaluation, systematic and narrative reviews and when and how to apply them. This book addresses the kinds of questions novice investigators always ask and helps students utilise study designs, data collection tools and analysis effectively.

The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine

Download The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9811053111
Total Pages : 394 pages
Book Rating : 4.8/5 (11 download)

DOWNLOAD NOW!


Book Synopsis The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine by : Richard Eugene Frye

Download or read book The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine written by Richard Eugene Frye and published by Springer. This book was released on 2018-09-20 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer’s disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive disorder, schizophrenia, traumatic brain injury and trichotillomania in addition to promising studies in audiology, cardiology, exercise physiology, gastroenterology, hematology, infectious disease, infertility and ophthalmology. Given the promising studies for a wide range of medical conditions, coupled with a excellent safety profile, the potential for NAC in the treatment of human disease appears considerable. Dr Leonore A Herzenberg from Stanford University, a pioneer of redox physiology and the use of NAC, provides a succinct history of the development of the therapeutic use of NAC for medical disease. This is followed by a series of basic science chapters outlining the role of NAC in important physiological processes, including modulation of dopamine and glutamate neurotransmitter systems, redox and mitochondrial metabolism, apoptosis and inflammation. The last section of the book is dedicated to clinically oriented chapters that comprehensively review the literature on medical disorders in which NAC has been found to be effective, including toxicity and cardiovascular, gastrointestinal, neurological, psychiatric, pulmonary and renal disorders. Each chapter reviews the theoretical biological mechanisms of NAC for the specific diseases reviewed, rates the clinical studies using a standardized criteria in order to provide an objective level of evidence and grade of recommendation for the use of NAC for specific medical conditions and outlines the ongoing clinical trials examining NAC for the treatment of specific diseases. Final chapters review the clinical evidence verifying that specific theoretical biological mechanisms are actually being targeted by NAC in medical disease. Studies on the pharmacology, formulation and potential adverse effects of NAC are also reviewed. A final chapter synthesizes the clinical studies to suggest that the effectiveness of NAC may signal a new basic physiological disorder, glutathione deficiency, which may be an important pathophysiological mechanism of many diseases.

Developmental-behavioral Pediatrics

Download Developmental-behavioral Pediatrics PDF Online Free

Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 032304025X
Total Pages : 994 pages
Book Rating : 4.3/5 (23 download)

DOWNLOAD NOW!


Book Synopsis Developmental-behavioral Pediatrics by : Mark Wolraich

Download or read book Developmental-behavioral Pediatrics written by Mark Wolraich and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the Diagnostic and Statistical Manual for Primary Care: Child and Adolescent Version (DSM-PC), this state-of-the-art reference expertly guides you through normal and abnormal development and behavior for all pediatric age groups. See how neurobiological, environmental, and human relationship factors all contribute to developmental and behavioral disorders and know how to best diagnose and treat each patient you see. Accurately identify developmental and behavioral problems using the Diagnostic and Statistical Manual for Primary Care criteria, and evidence-based guidelines. Gain a clear understanding of the "normal" boundaries and variations within specific disorders. Make informed therapeutic decisions with the integration of basic science and practical information and recommendations from the Society of Developmental and Behavioral Pediatrics and the American Academy of Pediatrics. Avoid legal and ethical implications by consulting the Law, Policy, and Ethics chapter. Download the DSM PC criteria from the included CD, as well as tables and illustrations for use in electronic presentations.

Handbook of Iron Overload Disorders

Download Handbook of Iron Overload Disorders PDF Online Free

Author :
Publisher : Cambridge University Press
ISBN 13 : 1139489399
Total Pages : pages
Book Rating : 4.1/5 (394 download)

DOWNLOAD NOW!


Book Synopsis Handbook of Iron Overload Disorders by : James C. Barton

Download or read book Handbook of Iron Overload Disorders written by James C. Barton and published by Cambridge University Press. This book was released on 2010-07-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical, clinically-oriented handbook of iron overload disorders giving a compact guide to normal iron metabolism, iron-related pathobiology, and the diagnosis and management of heritable and acquired iron overload disorders. Many of these disorders were discovered and characterized only in the last decade, and are unmentioned or inadequately described in most texts. Written by clinicians for clinicians, this handbook summarizes information on diverse iron overload conditions, including their history, signs, symptoms, physical examination findings, genetics, genotype-phenotype correlations, pathophysiology, differential diagnosis and treatment. Most physicians, regardless of specialty, encounter patients with systemic or organ-specific iron overload conditions. This book contains essential information for practising adult and pediatric medical specialists in the fields of hematology, gastroenterology, hepatology, rheumatology, endocrinology, diabetology, neurology, oncology, dermatology and internal medicine. Pathologists, pharmacologists, geneticists, genetic counselors and epidemiologists will also find substantial, up-to-date sections in this handbook that are pertinent to their respective fields of interest.

WHO guideline for clinical management of exposure to lead

Download WHO guideline for clinical management of exposure to lead PDF Online Free

Author :
Publisher : World Health Organization
ISBN 13 : 9240036881
Total Pages : 16 pages
Book Rating : 4.2/5 (4 download)

DOWNLOAD NOW!


Book Synopsis WHO guideline for clinical management of exposure to lead by :

Download or read book WHO guideline for clinical management of exposure to lead written by and published by World Health Organization. This book was released on 2021-10-28 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: