Etude De La Transmission Sexuelle Du Vih Dans Le Modele Du Macaque Infecte Experimentalement Par Le Siv Ou Un Virus Chimere Shiv

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Natural Hosts of SIV

Author : Aftab A. Ansari
Publisher : Newnes
ISBN 13 : 0124051677
Total Pages : 415 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Natural Hosts of SIV by : Aftab A. Ansari

Download or read book Natural Hosts of SIV written by Aftab A. Ansari and published by Newnes. This book was released on 2014-07-04 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural hosts maintain similar levels of plasma and cellular viremia and exhibit compellingly different, essentially disease-free, states. This work attempts to answer the question of how the natural host remains disease resistant. - Summarizes the past 30 years of research in this field and describes the latest developments in AIDS research using nonhuman primate animal models - Provides insights into how this large body of scientific work can be translated into novel approaches to treat and prevent HIV - Highlights the areas that merit future pursuit, focusing on potential applications for the treatment and prevention of HIV infection

Animal model studies on viral infections

Author : Akio Adachi
Publisher : Frontiers Media SA
ISBN 13 : 2889194566
Total Pages : 174 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Animal model studies on viral infections by : Akio Adachi

Download or read book Animal model studies on viral infections written by Akio Adachi and published by Frontiers Media SA. This book was released on 2015-03-13 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding viral replication and pathogenicity properties in infected individuals is a major mission of animal virology. Animal models are essential to analyze the in vivo viral characteristics and to develop countermeasures against viruses. To fight against a wide variety of viruses, basic studies with specific and/ or common approaches are required. This Research Topic collects articles that describe studies on numerous virus species at various stages toward animal experiments: (i) description/evaluation/ new challenges of animal model studies; (ii) experimental material/methods for animal model studies; (iii) observations for upcoming animal model studies. Numbers of DNA and RNA viruses such as HHV-6, HPV, Ebola virus, HCV, dengue virus, HTLV-1, HIV-1, SIV, and measles virus are covered by this special issue consisting of original research, methods, review, mini-review, and opinion articles. All readers would understand, we believe and hope, that animal model studies are critical for current virology as always.

Transmission sexuelle de l'infection par le VIH

Author : Laurent Belec
Publisher : John Libbey Eurotext
ISBN 13 : 2742009361
Total Pages : 677 pages
Book Rating : 4.7/5 (42 download)

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Book Synopsis Transmission sexuelle de l'infection par le VIH by : Laurent Belec

Download or read book Transmission sexuelle de l'infection par le VIH written by Laurent Belec and published by John Libbey Eurotext. This book was released on 2007-01-01 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: L'infection par le VIH est par essence une maladie transmissible à travers les barrières muqueuses. Cette constatation, évidente mais souvent oubliée, oblige à s'intéresser aux interactions incipiens entre les muqueuses et le VIH, comme orientation première de toutes prolégomènes sur la physiopathologie de cette infection virale. Plus de 30 ans après la découverte du VIH, le domaine de la recherche scientifique étudiant les mécanismes biologiques et comportementaux impliqués dans la transmission muqueuse du VIH est désormais devenue une discipline multidisciplinaire, complexe et évolutive. Les étudiants, médecins et chercheurs spécialisés dans le domaine du sida ont acquis des connaissances remarquables en ce qui concerne l'histoire naturelle de la maladie, son diagnostic et sa prise en charge thérapeutique, alors que leurs connaissances en immunité et virologie muqueuse, ainsi qu'en sciences du comportement, souffrent d'un manque évident de repères. Or, seules des connaissances précises dans ce domaine permettront d'appréhender les innombrables conséquences de la transmission muqueuse du VIH, comme l'orientation barycentrique de l'épidémie de sida en direction des pays en développement, la résurgence des anciens fantasmes et des vieilles métaphores concernant les maladies sexuellement transmissibles contagieuses incurables, les discriminations associées aux pratiques sexuelles minoritaires, et aussi de comprendre les enjeux de la recherche contemporaine sur l'infection par le VIH, comme la compréhension du phénomène insolite de résistance à l'acquisition sexuelle du VIH, ou encore la conception et le développement de microbicides ou de vaccins prophylactiques par voie muqueuse. L'ouvrage, publié sous la direction de Laurent Bélec, regroupe un ensemble remarquable d'auteurs, chacun ayant été sélectionné pour sa grande compétence dans un domaine spécifique. Il offre la synthèse des recherches et des problématiques œuvrant dans le champ de la transmission muqueuse du VIH, non seulement à un public de chercheurs avertis, mais aussi à tous les spécialistes de l'infection par le VIH, et par extension à tout esprit curieux.

Simian Immunodeficiency Virus

Author : Norman L. Letvin
Publisher : Springer
ISBN 13 : 9783642785375
Total Pages : 241 pages
Book Rating : 4.7/5 (853 download)

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Book Synopsis Simian Immunodeficiency Virus by : Norman L. Letvin

Download or read book Simian Immunodeficiency Virus written by Norman L. Letvin and published by Springer. This book was released on 2011-12-27 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the lentivirus subfamily of retroviruses has greatly intensified due to the realization that HIV-1 and HIV-2 are members of this previously obscure group. Related lentiviruses have now been isolated from sheep, goats, horses, cattle, cats, monkeys, and humans. This issue of CTMI is devoted to the lentiviruses of nonhuman primates, referred to as simian immunodeficiency viruses (SIVs). The SIVs provide valuable tools for our quest to understand and control the HIVs, which are obviously important new human pathogens. Included in this volume are discussions of the distribution and molecular phylogeny of the SIVs and their use as animal models for the study of AIDS pathogenesis, and the chapters clearly illustrate how SIV models are contributing to our understanding of the ability of host immune responses to control infection at least temporarily and the ability of virus to evade these host immune defenses.