Author : Asma Altasan
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)
Book Synopsis Ethnic, Body Composition and Dietary Factors as Determinants of Vitamin D Status by : Asma Altasan
Download or read book Ethnic, Body Composition and Dietary Factors as Determinants of Vitamin D Status written by Asma Altasan and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: Vitamin D deficiency (VDD) is a worldwide problem that can take an essential part in developing many chronic diseases, including but not limited to type 2 diabetes, metabolic syndrome, and cardiovascular diseases (CVD). There are many factors that can contribute to VDD or make specific populations or individuals at higher risk to develop VDD and its related health consequences. These factors include and are not limited to the ethnic background, body composition, and dietary intake of nutrients. It has been found that South Asian Indians (SAIs) are at higher risk of developing CVD and metabolic syndrome compared to their Caucasian counterparts, and at a younger age. Also, there is a high prevalence of VDD among SAIs living in their countries or in European countries. In addition, SAIs found to have a higher deposition of fat in their visceral areas compared to Caucasians. Considering that many SAIs follow restricted diets (as many follow a vegan or a vegetarian diet), which may put them at higher risk for nutrients deficiencies; it was worthy to investigate the effect of SAI ethnicity, body composition, and micronutrients intake of calcium (Ca), magnesium (Mg), and their ratio on the vitamin D status. Vitamin D status can be assessed using serum 25-hydroxyvitamin D (s25(OH)D), serum parathyroid hormone(sPTH), and serum vitamin D binding protein (sDBP). Both dietary intake of Ca and Mg were independently associated with s25(OH)D as their deficiencies were associated with VDD. Also, the intake of both is deficient among approximately half of the US population. Some studies' efforts focused on finding the optimal dietary Ca to Mg ratio for optimal health outcomes. Since both Ca and Mg share similarities in the absorption sites and functionality, and since both are independently associated with VDD, it was worth investigating if their dietary intake ratio is associated with vitamin D status among SAIs, Caucasians, and among both of them collectively. Our primary aims were to investigate if biomarkers of vitamin D statusØ+ body composition parameters, and dietary factors are different between SAIs and Caucasians and to understand the relationship between them. Methods: Healthy SAIs and Caucasian men between 22 to 60 years of age were enrolled. Anthropometric and body composition measurements, biochemical analyses for s25(OH)D, sPTH, and sDBP, and habitual dietary intakes of Ca and Mg were obtained. Independent t-test and Mann-Whitney u test were used to report the differences between groups in their vitamin D status, body composition, and dietary intakes. Pearson or Spearman correlations were used to identify the possible associations. A P value of less than 0.05 was considered significant. Results: 30 SAIs and 30 Caucasians completed the study. Both groups did not significantly differ in their age and BMI. SAIs, compared to the Caucasians, had significantly lower s25(OH)D (22.79 ℗ł 9.1 vs 31.24 ℗ł 9.1 ng/mL; P