Essentials Of Laboratory Animal Science Principles And Practices

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Essentials of Laboratory Animal Science: Principles and Practices

Author : P. Nagarajan
Publisher : Springer Nature
ISBN 13 : 981160987X
Total Pages : 797 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Essentials of Laboratory Animal Science: Principles and Practices by : P. Nagarajan

Download or read book Essentials of Laboratory Animal Science: Principles and Practices written by P. Nagarajan and published by Springer Nature. This book was released on 2021-07-23 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

Fundamentals of Laboratory Animal Science

Author : Enqi Liu
Publisher : CRC Press
ISBN 13 : 1315351994
Total Pages : 347 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Fundamentals of Laboratory Animal Science by : Enqi Liu

Download or read book Fundamentals of Laboratory Animal Science written by Enqi Liu and published by CRC Press. This book was released on 2017-07-28 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory animals are becoming increasingly important for biomedical research. It is said that approximately 70% of biomedical research is associated with the use of experimental animals. Laboratory animal research not only expands our knowledge of science, but also greatly improves human and animal health. The field of laboratory animal science is ever-growing and changing as new experimental techniques are developed and new animal models are created. It is essential to know not only the biological features of each laboratory animal but also how to use and care for them responsibly in order to perform high-quality experiments. Courses in beginning Laboratory Animal Science are starting to be offered in many universities throughout the world. However, a practical introductory textbook that contains state-of-the-art techniques is still lacking. Fundamentals of Laboratory Animal Science provides comprehensive information on the principles and practices of using laboratory animals for biomedical research. Each individual chapter focuses on a key sub-discipline of laboratory animal science: animal welfare and best humane care practices in the laboratory; the quality control of laboratory animals; the anatomy, physiology, and husbandry of commonly used species; the principles of creating and using animal models for studying human diseases; practical techniques used for laboratory animal experiments; experimental design; and animal experimentation management. Knowledge of this broad spectrum of concepts and skills will ensure research goes smoothly while greatly reducing animal pain and distress. Well-illustrated and thoroughly referenced, this book will serve not only as a standard textbook but also as a handy guide for veterinarians, researchers, animal care staff, administrators, and other professionals who are involved in laboratory animal science.

Handbook of Laboratory Animal Science

Author : Jann Hau
Publisher : CRC Press
ISBN 13 : 0429801599
Total Pages : 1890 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Handbook of Laboratory Animal Science by : Jann Hau

Download or read book Handbook of Laboratory Animal Science written by Jann Hau and published by CRC Press. This book was released on 2021-05-17 with total page 1890 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide. It covers the essential principles and practices of Laboratory Animal Science as well as selected animal models in scientific disciplines where much progress has been made in recent years. Each individual chapter focuses on an important subdiscipline of laboratory animal science, and the chapters can be read and used as stand-alone texts, with only limited necessity to consult other chapters for information. With new contributors at the forefront of their fields, the book reflects the scientific and technological advances of the past decade. It also responds to advances in our understanding of animal behavior, emphasizing the importance of implementing the three Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort. This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university veterinarians, and for other specialists in laboratory animal science.

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by : National Research Council

Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Principles of Laboratory Animal Science

Author : L. F. M. van Zutphen
Publisher : Elsevier Science Health Science Division
ISBN 13 : 9780444506122
Total Pages : 416 pages
Book Rating : 4.5/5 (61 download)

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Book Synopsis Principles of Laboratory Animal Science by : L. F. M. van Zutphen

Download or read book Principles of Laboratory Animal Science written by L. F. M. van Zutphen and published by Elsevier Science Health Science Division. This book was released on 2001 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The welfare of laboratory animals, as well as the ethical issues involved in the humane use of animals for scientific purposes, are discussed in this new revised edition. Information is included on the biology and husbandry of animal models; on behavior, stress and well-being; genetic and microbiological standardization; health monitoring; anaesthesiology; animal alternatives; ethics. This book addresses all of the aspects that scientists need to know when considering the design of an animal experiment. Replacement, reduction and refinement of animal experiments are the guiding principles for its contents.

Biosecurity in Animal Production and Veterinary Medicine

Author : Jeroen Dewulf
Publisher : CABI
ISBN 13 : 1789245680
Total Pages : 525 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Biosecurity in Animal Production and Veterinary Medicine by : Jeroen Dewulf

Download or read book Biosecurity in Animal Production and Veterinary Medicine written by Jeroen Dewulf and published by CABI. This book was released on 2019-12-01 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, the way the animal production industry copes with infectious diseases is changing. The (excessive) use of antimicrobials is under debate and it is becoming standard practice to implement thorough biosecurity plans on farms to prevent the entry and spread of pathogenic micro-organisms. Not only in farm animal production, but also in facilities where companion animals are kept, including in veterinary practices and clinics, awareness of the beneficial implications of a good biosecurity plan has raised. The book Biosecurity in Animal Production and Veterinary Medicine is the first compilation of both fundamental aspects of biosecurity practices, and specific and practical information on the application of the biosecurity measures in different animal production and animal housing settings.

Education and Training in the Care and Use of Laboratory Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309043824
Total Pages : 152 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Education and Training in the Care and Use of Laboratory Animals by : National Research Council

Download or read book Education and Training in the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 1991-02-01 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Federal law now requires that institutions provide training for anyone caring for or using laboratory animals. This volume provides the guidelines and resources needed to coordinate a quality training program, as well as to meet all legal requirements. A core module for all personnel takes no more than four hours to present. Most staff then proceed to one or more additional skills-development modules including the species-specific module that can be customized to any species in use at the institution, the pain management module, and the surgery module. The volume provides content information for required topics-from ethics to record keeping-and lists sources of additional publications, audiovisual programs, and computerized teaching aids. Included are: Ready-to-use teaching outlines, with detailed instructions for presenting material. Practical guidelines on logistics, covering scheduling, budgeting, and more. Guidelines on how to design training for adults and how to work with investigators who may resist taking training courses. This practical guidebook will be necessary for research institutions, particularly for staff members responsible for training coordination.

Handbook of Laboratory Animal Science

Author : Jann Hau
Publisher : CRC Press
ISBN 13 : 142004091X
Total Pages : 569 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Laboratory Animal Science by : Jann Hau

Download or read book Handbook of Laboratory Animal Science written by Jann Hau and published by CRC Press. This book was released on 2002-10-28 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of an international bestseller, this book provides veterinary specialists as well as veterinary and biomedical researchers with detailed information about laboratory animal genetics, diseases, health monitoring, nutrition, and environmental impact on animal experiments. Completely revised and updated, Volume I now contains expand

Small Animal Toxicology Essentials

Author : Robert H. Poppenga
Publisher : John Wiley & Sons
ISBN 13 : 081381538X
Total Pages : 355 pages
Book Rating : 4.8/5 (138 download)

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Book Synopsis Small Animal Toxicology Essentials by : Robert H. Poppenga

Download or read book Small Animal Toxicology Essentials written by Robert H. Poppenga and published by John Wiley & Sons. This book was released on 2011-05-31 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a ready reference for the initial triage, collection of diagnostic samples, and management of a poisoning case, Small Animal Toxicology Essentials focuses on the most common poisons encountered by companion animals. From prevention to evaluation, monitoring, and treatment, the book is a guide for veterinary technicians to differentiate between significant and insignificant exposures and effectively manage animal poisonings. Emphasizing clinical signs, differential diagnoses, and case management, the book begins with the principles of veterinary toxicology, such as terminology, history-taking, and decontamination. The second half of the book is devoted to specific toxicants, including plants, metals, drugs, and household poisons. A companion website at www.wiley.com/go/poppenga provides review questions in Word and color images available for download into PowerPoint. Small Animal Toxicology Essentials is a useful resource for veterinary technicians, especially those with a interest in emergency and critical care, and veterinary technician students, as well as practicing veterinarians looking for an introduction to toxicology.

Current Protocols Essential Laboratory Techniques

Author : Sean R. Gallagher
Publisher : John Wiley & Sons
ISBN 13 : 047094241X
Total Pages : 679 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Current Protocols Essential Laboratory Techniques by : Sean R. Gallagher

Download or read book Current Protocols Essential Laboratory Techniques written by Sean R. Gallagher and published by John Wiley & Sons. This book was released on 2012-03-19 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest title from the acclaimed Current Protocols series, Current Protocols Essential Laboratory Techniques, 2e provides the new researcher with the skills and understanding of the fundamental laboratory procedures necessary to run successful experiments, solve problems, and become a productive member of the modern life science laboratory. From covering the basic skills such as measurement, preparation of reagents and use of basic instrumentation to the more advanced techniques such as blotting, chromatography and real-time PCR, this book will serve as a practical reference manual for any life science researcher. Written by a combination of distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, 2e is the cornerstone on which the beginning scientist can develop the skills for a successful research career.

Animal Cell Culture

Author : John M. Davis
Publisher : John Wiley & Sons
ISBN 13 : 0470975636
Total Pages : 389 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Animal Cell Culture by : John M. Davis

Download or read book Animal Cell Culture written by John M. Davis and published by John Wiley & Sons. This book was released on 2011-03-16 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive research guide that describes both the key new techniques and more established methods. Every chapter discusses the merits and limitations of the various approaches and then provides selected tried-and-tested protocols, as well as a plethora of good practical advice, for immediate use at the bench. It presents the most accessible and comprehensive introduction available to the culture and experimental manipulation of animal cells. Detailed protocols for a wide variety of methods provide the core of each chapter, making new methodology easily accessible. This book is an essential laboratory manual for all undergraduates and graduates about to embark on a cell culture project. It is a book which both experienced researchers and those new to the field will find invaluable.

The Laboratory Guinea Pig

Author : Donna J. Clemons
Publisher : CRC Press
ISBN 13 : 1000218759
Total Pages : 179 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis The Laboratory Guinea Pig by : Donna J. Clemons

Download or read book The Laboratory Guinea Pig written by Donna J. Clemons and published by CRC Press. This book was released on 2016-04-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory animals play an important role in biomedical research and advances. Expanded, updated, and now published in full color to provide greater clarity to the techniques and concepts discussed, this guide presents basic information and common procedures in detail to provide a quick reference for investigators, technicians, and caretakers in the laboratory setting. It includes additional information on the research uses of the guinea pig along with updated medical care information.

Handbook of Laboratory Animal Science, Volume I

Author : Jann Hau
Publisher : CRC Press
ISBN 13 : 1420084569
Total Pages : 758 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Laboratory Animal Science, Volume I by : Jann Hau

Download or read book Handbook of Laboratory Animal Science, Volume I written by Jann Hau and published by CRC Press. This book was released on 2010-12-02 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory animal testing provides most of our current knowledge of human physiology, microbiology, immunology, pharmacology, and pathology. From studies of genetics in fruit flies to studies of cellular processes in genetically modified mice to recent dramatic developments in genetics, translational research, and personalized medicines, biomedical

Guide for the Care and Use of Laboratory Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309154006
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Animal Models in Research

Author : Harikrishnan Vijayakumar Sreelatha
Publisher : Springer Nature
ISBN 13 : 9819700485
Total Pages : 645 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Animal Models in Research by : Harikrishnan Vijayakumar Sreelatha

Download or read book Animal Models in Research written by Harikrishnan Vijayakumar Sreelatha and published by Springer Nature. This book was released on with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Basic Principles of Drug Discovery and Development

Author : Benjamin E. Blass
Publisher : Academic Press
ISBN 13 : 0128172150
Total Pages : 738 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Basic Principles of Drug Discovery and Development by : Benjamin E. Blass

Download or read book Basic Principles of Drug Discovery and Development written by Benjamin E. Blass and published by Academic Press. This book was released on 2021-03-30 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator's fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist's early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. - Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property - Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape - Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery - Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry

Rodent Model as Tools in Ethical Biomedical Research

Author : Monica Levy Andersen
Publisher : Springer
ISBN 13 : 3319115782
Total Pages : 514 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Rodent Model as Tools in Ethical Biomedical Research by : Monica Levy Andersen

Download or read book Rodent Model as Tools in Ethical Biomedical Research written by Monica Levy Andersen and published by Springer. This book was released on 2015-11-26 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.