Erythrocytes as Drug Carriers in Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1489900446
Total Pages : 149 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Erythrocytes as Drug Carriers in Medicine by : Ulrich Sprandel

Download or read book Erythrocytes as Drug Carriers in Medicine written by Ulrich Sprandel and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sixth meeting on the use of resealed annealed red blood cells was held in Irsee, Germany by the International Society for the Use of Resealed Erythrocytes (ISURE) on July 25-28, 1996. Although earlier meetings focused on the technology toward develop ment of methods and standardization for efficient, consistent encapsulation, most of the present studies now are directed toward the application use of these carrier blood cells. Basic studies now have been directed toward exploration of commercial applications. In deed, clinical trials were initiated to evaluate the dose-response curves employing L asparagenase in human patients. Also, studies have shown the use of thrombolytic agent in erythrocyte carriers with the use of human red blood cells to provide a new conceptual ap proach in thrombolytic therapy to prevent thrombosis in individuals with higher risk fac tors. For example, with the use of carrier red blood cells, the thrombolytic agents will have a greater potential of acting on clot formation without systemic activation and thus lower the risk of hemorrhage, which is always prevalent in the thrombolytic therapy.

Erythrocyte Engineering for Drug Delivery and Targeting

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306476914
Total Pages : 240 pages
Book Rating : 4.4/5 (769 download)

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Book Synopsis Erythrocyte Engineering for Drug Delivery and Targeting by : Mauro Magnani

Download or read book Erythrocyte Engineering for Drug Delivery and Targeting written by Mauro Magnani and published by Springer Science & Business Media. This book was released on 2003-01-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Symposia on Plant Lipids, the 15th of which was held in Okazaki, Japan, in May 12-17, 2002, is held every two years and is the only international meeting in this field. The contributions from the symposium collected in this book represent the most up-to-date research results on plant lipids, including their structure, analysis, biosynthesis, regulation, physiological function, environmental aspects, and biotechnology, obtained world-wide during 2000-2002

Carrier and Bioreactor Red Blood Cells for Drug Delivery and Targeting

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Publisher : Pergamon Press
ISBN 13 : 9780080424965
Total Pages : 200 pages
Book Rating : 4.4/5 (249 download)

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Book Synopsis Carrier and Bioreactor Red Blood Cells for Drug Delivery and Targeting by : John R. DeLoach

Download or read book Carrier and Bioreactor Red Blood Cells for Drug Delivery and Targeting written by John R. DeLoach and published by Pergamon Press. This book was released on 1994-01-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of research papers on erythrocyte encapsulation. It covers immunotargeting using erythrocyte carriers and should be useful to those exploring ways to improve drug delivery. It also covers biochemical studies on the erythrocyte and is relevant to studies of circulating bioreactors.

The Use of Resealed Erythrocytes as Carriers and Bioreactors

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Publisher : Springer Science & Business Media
ISBN 13 : 146153030X
Total Pages : 342 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Use of Resealed Erythrocytes as Carriers and Bioreactors by : Mauro Magnani

Download or read book The Use of Resealed Erythrocytes as Carriers and Bioreactors written by Mauro Magnani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently the only biomedical use of erythrocytes was in transfusion medicine to restore a normal oxygen delivery. The development of a technology that permits one to open and reseal erythrocytes has dramatically changed this perspective. Currently, a number of teams have shown that engineered erythrocytes can behave as circulating bioreactors for the degradation of toxic metabolites or the inactivation of xenobiotics, as drug delivery systems, as carriers of antigens of vaccinal interest, and in many others biomedical applications. The technology of opening and resealing the erythrocytes has also been used successfully to investigate several basic aspects of erythrocyte metabolism, survival, pathology, etc. Thus, researchers in this field have an extraordinary opportunity to specifically modify the erythrocytes by the introduction of enzymes that generate new metabolic abilities, antibodies that inactivate single metabolic steps, or metabolites that can influence oxygen delivery and/or other cell properties. Furthermore, the pharmacokinetics of any drug can be potentially manipulated by using the erythrocytes as a delivery system. This book, The Use of Resealed Erythrocytes, is based on the fourth meeting of the "International Society for the Use of Resealed Erythrocytes as Carriers and Bioreactors" (I. S. U. R. E. ), held in Urbino, Italy, in 1991, and examines the most recent applications and developments of this technology.

Drug Carriers in Biology and Medicine

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Publisher :
ISBN 13 :
Total Pages : 394 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Drug Carriers in Biology and Medicine by : Gregory Gregoriadis

Download or read book Drug Carriers in Biology and Medicine written by Gregory Gregoriadis and published by . This book was released on 1979 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Erythrocyte Engineering for Drug Delivery and Targeting

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Author :
Publisher : Eurekah.Com Incorporated
ISBN 13 : 9781587060618
Total Pages : 148 pages
Book Rating : 4.0/5 (66 download)

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Book Synopsis Erythrocyte Engineering for Drug Delivery and Targeting by : Mauro Magnani

Download or read book Erythrocyte Engineering for Drug Delivery and Targeting written by Mauro Magnani and published by Eurekah.Com Incorporated. This book was released on 2003 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanoparticulates as Drug Carriers

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Publisher : Imperial College Press
ISBN 13 : 186094907X
Total Pages : 758 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis Nanoparticulates as Drug Carriers by : V. P. Torchilin

Download or read book Nanoparticulates as Drug Carriers written by V. P. Torchilin and published by Imperial College Press. This book was released on 2006 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposomal Drug Carriers in Cancer Therapy (A A Gabizon); Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw); Nanoparticles for Targeting Lymphatics (W Phillips); Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso); and other papers. Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging."

Drug Carrier Systems

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Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Drug Carrier Systems by : A. M. Kroon

Download or read book Drug Carrier Systems written by A. M. Kroon and published by John Wiley & Sons. This book was released on 1989 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the main developments of the past 20 years, relating advances in systems that release the active drug in a sustained and controlled way, and new drugs that address more specifically the tissues and cells with which they are designed to interact. Considers the problems of biodistribution and biodegradation, with in-depth discussion of the selectivity and toxicity of the drugs administered by the various carrier systems. Topics covered range from antibodies, polymers, liposomes, erythrocytes and erythrocyte ghosts, to implantable infusion pumps. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

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Publisher : Springer Science & Business Media
ISBN 13 : 9400760108
Total Pages : 433 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment by : Jorge Coelho

Download or read book Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment written by Jorge Coelho and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Liposomes in Drug Delivery

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Publisher : Routledge
ISBN 13 : 1351435043
Total Pages : 278 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Liposomes in Drug Delivery by : AlexanderT. Florence

Download or read book Liposomes in Drug Delivery written by AlexanderT. Florence and published by Routledge. This book was released on 2017-10-05 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

Fundamentals of Drug Delivery

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Publisher : John Wiley & Sons
ISBN 13 : 1119769604
Total Pages : 580 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Fundamentals of Drug Delivery by : Heather A. E. Benson

Download or read book Fundamentals of Drug Delivery written by Heather A. E. Benson and published by John Wiley & Sons. This book was released on 2021-10-12 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Drug Delivery Systems in Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 1592594271
Total Pages : 438 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Drug Delivery Systems in Cancer Therapy by : Dennis M. Brown

Download or read book Drug Delivery Systems in Cancer Therapy written by Dennis M. Brown and published by Springer Science & Business Media. This book was released on 2003-09-08 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Blood Substitutes, Present and Future Perspectives

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Publisher : Elsevier
ISBN 13 : 008052821X
Total Pages : 409 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Blood Substitutes, Present and Future Perspectives by : E. Tsuchida

Download or read book Blood Substitutes, Present and Future Perspectives written by E. Tsuchida and published by Elsevier. This book was released on 1999-01-14 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997. In keeping with the scientific design of the 7th ISBS Symposium, chapters have been carefully selected and organized to showcase the advancements in recent research. This book includes up-to-date clinical results of leading companies which are manufacturing hemoglobin-based or fluorocarbon-based blood substitutes, and covers issues of hemoglobin toxicity and side effects such as vasoconstriction in more detail using carefully designed in vivo and ex vivo techniques. This book is also a collection of various new types of red cell substitutes such as recombinant Hbs, recombinant albumine-lipidheme complex, modified red blood cells, and perfluorochemicals using material science and molecular engineering.

Red Blood Cells as Carriers for Drugs, Potential Therapeutic Applications

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Publisher : Pergamon
ISBN 13 : 9780080361376
Total Pages : 260 pages
Book Rating : 4.3/5 (613 download)

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Book Synopsis Red Blood Cells as Carriers for Drugs, Potential Therapeutic Applications by : C. Ropars

Download or read book Red Blood Cells as Carriers for Drugs, Potential Therapeutic Applications written by C. Ropars and published by Pergamon. This book was released on 1987 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This book is a general survey of the present status of the encapsulation of xenobiotics in red blood cells and their potential therapeutic utilisation. The various participants have illustrated three general domains: 1) modification of autologous red blood cell oxygen transport properties; 2) encapsulation of enzymes and creation of circulating bioreactors; and 3) encapsulation of drugs, mainly for anticancer and antiparasitic therapy, and targeting on the reticulo-endothelial system.

Targeted & Controlled Drug Delivery: Novel Carrier Systems (HB)

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Publisher :
ISBN 13 : 9788123907994
Total Pages : 594 pages
Book Rating : 4.9/5 (79 download)

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Book Synopsis Targeted & Controlled Drug Delivery: Novel Carrier Systems (HB) by : Vyas; Khar

Download or read book Targeted & Controlled Drug Delivery: Novel Carrier Systems (HB) written by Vyas; Khar and published by . This book was released on 2006-02-01 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Red Blood Cells as Carriers for Drugs

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Author :
Publisher : S Karger Ag
ISBN 13 : 9783805539401
Total Pages : 0 pages
Book Rating : 4.5/5 (394 download)

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Book Synopsis Red Blood Cells as Carriers for Drugs by : John R. DeLoach

Download or read book Red Blood Cells as Carriers for Drugs written by John R. DeLoach and published by S Karger Ag. This book was released on 1985 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Delivery Systems

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Drug Delivery Systems by : R. L. Juliano

Download or read book Drug Delivery Systems written by R. L. Juliano and published by Oxford University Press, USA. This book was released on 1980 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: