Author : Tao Sun
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (115 download)
Book Synopsis Epithelial-Mesenchymal Transition and Its Regulation in Tumor Metastasis by : Tao Sun
Download or read book Epithelial-Mesenchymal Transition and Its Regulation in Tumor Metastasis written by Tao Sun and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Epithelial-mesenchymal transition (EMT) plays a key role in cancer metastasis. This process is a complex, multi-functional, and tightly regulated developmental program. EMT has been extensively investigated, but the molecular regulation of its signaling pathway is highly complex. In this study, the different elements of EMT cascades that could be targeted were determined. Difficulties in translating the preclinical findings in routine clinic were also distinguished. Future research will provide insights into the activation and regulation of various EMT programs in different tumor types and at distinct stages of tumor development. These results will likely facilitate the development of early detection strategies and improve the therapeutic targeting of malignant solid tumors.