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Epidemiologic Investigation Of Health Effects In Air Force Personnel Following Exposure To Herbicides
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Book Synopsis Disposition of the Air Force Health Study by : Institute of Medicine
Download or read book Disposition of the Air Force Health Study written by Institute of Medicine and published by National Academies Press. This book was released on 2006-05-25 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vietnam War was fought in a jungle environment that provided cover to the enemy and made battlefield observations difficult, so military strategists used herbicides to remove foliage along key roads and waterways, defoliate areas surrounding enemy bases and supply and communications routes, and improve visibility in heavily canopied forests. The last three decades have seen an ongoing debate about the effects of this military use of herbicides and the potential adverse long-term health effects on those who may have been exposed to these herbicides. In response to these concerns, the Air Force Health Study (AFHS) was created to investigate the potential relationship between the herbicides used and the health problems of those exposed. Disposition of the Air Force Health Study assesses the scientific merit of the AFHS operations and procedures, and makes recommendations for improvement.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by : William H. Wolfe
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by William H. Wolfe and published by . This book was released on 1989 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by and published by . This book was released on 1990 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Air Force Health Study (Project RANCH HAND II). An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Morbidity Study Results by : George D. Lathrop
Download or read book Air Force Health Study (Project RANCH HAND II). An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Morbidity Study Results written by George D. Lathrop and published by . This book was released on 1984 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1979 the United States Air Force (USAF) made the commitment to Congress and to the White House to conduct an epidemiologic study of the possible health effects from chemical exposure in Air Force personnel who conducted aerial herbicide dissemination missions in Vietnam (Operation RANCH HAND). The purpose of this epidemiologic investigation is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. This study uses a matched cohort design in a noncurrent prospective setting, incorporating mortality, morbidity, and follow-up studies. This report presents the results of health information on 2706 Ranch Handers and comparison individuals obtained by questionnaire and 2269 Ranch Handers and comparison individuals undergoing an extensive physical examination. This baseline report concludes that there is insufficient evidence to support a cause and effect relationship between herbicide exposure and adverse health in the Ranch Hand group at this time. The study has disclosed numerous medical findings, mostly of a minor or undetermined nature, that require detailed follow-up. In full context, the baseline study results should be viewed as reassuring to the Ranch Handers and to their families at this time.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This report summarizes results from the Air Force Health Study (AFHS). The AFHS is an epidemiological study to determine whether adverse health effects attributable to exposure to herbicides exist in veterans of Operation Ranch Hand. Operation Ranch Hand was the unit responsible for the aerial spraying of herbicides, including Herbicide Orange, in Vietnam from 1961 to 1971. A Comparison cohort comprised Air Force veterans who served in Southeast Asia during the same time period that the Ranch Hand unit was active and who were not involved with spraying herbicides. The summarized data were collected during a physical examination administered between May 1997 and April 1998. Of 1,149 eligible Ranch Hands, 870 (75.7%) participated and of 1,761 eligible Comparisons, 1,251 (71.0%) participated. Statistical analyses assessed differences between Ranch Hands and Comparisons and associations between health-related endpoints and extrapolated initial dioxin, dioxin exposure category (Comparisons, background Ranch Hands, low Ranch Hands, high Ranch Hands), and dioxin measured in 1987. The study has insufficient statistical power to assess increases in the risk of rare diseases, such as soft tissue sarcoma. Diabetes and cardiovascular abnormalities represent the most important dioxin-related health problems seen. From a public health perspective, these two areas demand the greatest attention."--Abstract.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume 2. First Followup Examination Results by : G. D. Lathrop
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume 2. First Followup Examination Results written by G. D. Lathrop and published by . This book was released on 1987 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report represent the result of the health assessment of the 1,016 Ranch Hands and the 1,293 Comparisons who participated in the 1985 followup examination of the Air Force health Study. The purpose of the study is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. The results show a subtle but consistent narrowing of medical differences between the two groups since the Baseline study in 1982, however, the Ranch Hands continue to manifest slightly more minor adverse health conditions than the Comparisons. Continued surveillance of these groups is indicated. The report concludes that there is not sufficient evidence to implicate a causal relationship between herbicide exposure and adverse health in the Ranch Hand group. Keywords: Epidemiologic investigation, Phenoxy herbicides, Herbicide orange, Dioxin, Morbidity, Health surveys, Air Force health study.
Book Synopsis Air Force Health Study. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. First Followup Examination Results by :
Download or read book Air Force Health Study. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. First Followup Examination Results written by and published by . This book was released on 1987 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report represents the results of the health assessment of the 1, 016 Ranch Hands and the 1,293 Comparisons who participated in the 1985 followup examination of the Air Force Health Study. The purpose of the study is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. The result show a subtle but consistent narrowing of medical differences between the two groups since the Baseline study in 1982; however, the Ranch Hands continue to manifest slightly more minor adverse health conditions than the Comparisons. Continued surveillance of these groups is indicated. The report concludes that there is not sufficient evidence to implicate a causal relationship between herbicide exposure and adverse health in the Ranch Hand group. Keywords: Health surveys; Epidemiologic investigation; Phenoxy herbicides; Herbicide orange; Dioxin; Air Force health study, Morbidity.
Book Synopsis Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Study Protocol by :
Download or read book Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Study Protocol written by and published by . This book was released on 1982 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1979 the United States Air Force (USAF) made the commitment to Congress and to the White House to conduct an epidemiologic study of the possible health effects from chemical exposure in Air Force personnel who conducted aerial herbicide dissemination missions in Vietnam (Operation RANCH HAND). The purpose of this epidemiologic investigation is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. This study uses a matched cohort design in a noncurrent prospective setting incorporating mortality, morbidity, and followup studies, Detailed computer searches of Air Force personnel records, with several cross-referencing techniques, have ensured total ascertainment of the RANCH HAND population. The unique circumstances of exposure in this population of 1264 individuals will permit a semiquantitative estimate of exposure. A comparison group will be formed from a population of 23,978 flight crew members and support personnel who were assigned to duty in Southeast Asia (SEA), but were not occupationally exposed to herbicides. These individuals will be matched to RANCH HAND personnel for the variables of age, type of job, and race. Since both the exposed subjects and their selected controls performed similar combat or combat-related jobs, many of the physical and psychophysiologic effects of combat stress and the SEA environment will also be equivalent in the two groups.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by : USAF School of Aerospace Medicine. Epidemiology Division
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by USAF School of Aerospace Medicine. Epidemiology Division and published by . This book was released on 1987 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume 1 by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume 1 written by and published by . This book was released on 1995 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report represents the results from an epidemiologic study to determine whether adverse health effects attributable to Herbicide Orange exist in Vietnam veterans who participated in Operation Ranch Hand. Data were analyzed for 12 clinical areas. The analysis focused on group differences between the exposed (Ranch Hand) and unexposed (Comparison) cohorts, as well as on the association of each health-related endpoint with extrapolated initial and current serum dioxin levels. Findings in this report reveal a consistent relationship between dioxin and body fat that was initially noted in the analysis of the 1987 examination results. Cholesterol and the cholesterol to HDL ratio were found to be associated with current serum dioxin levels. Evidence for a possible association between glucose intolerance, impaired insulin production, and dioxin exposure was revealed, but cause and effect remain to be established. Also revealed was a significant association between selected peripheral pulses and dioxin exposure, and a significant difference in self-perceived health status between Ranch Hands and Comparisons (although possible due to bias). Other health endpoints revealed no consistent patterns within or across clinical areas that were suggestive of health detriment due to dioxin exposure.
Book Synopsis Project RANCH HAND 2. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Mortality Study Results by :
Download or read book Project RANCH HAND 2. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Baseline Mortality Study Results written by and published by . This book was released on 1983 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1979 the United States Air Force (USAF) made the commitment to Congress and to the White House to conduct an epidemiologic study of the possible health effects from chemical exposure in Air Force personnel who conducted aerial herbicide dissemination missions in Vietnam (operation RANCH HAND). The purpose of this epidemiologic investigation is to determine whether long-term health effects exist and can be attributed to occupational exposure to herbicides. This study uses a matched cohort design in a nonconcurrent prospective setting, incorporating mortality, morbidity, and follow-up studies. The purpose of this report is to present the baseline mortality study results. As of December 31, 1982, 50 Ranch hand and 250 comparison subjects had died (certified on/before April 27, 1983). Data analysis showed that the mortality experience of the Ranch Hand group is nearly identical to that of this comparison group. However, this mortality report can in no way be regarded as conclusively negative since the study population may not yet have reached the latency period. Subsequent mortality reports will include additional analyses and will be updated annually for the next 20 years.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Extract by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Extract written by and published by . This book was released on 1995 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report represents the results from an epidemiologic study to determine whether adverse health effects attributable to Herbicide Orange exist in Vietnam veterans who participated in Operation Ranch Hand. Data were analyzed for 12 clinical areas. The analysis focused on group differences between the exposed (Ranch Hand) and unexposed (Comparison) cohorts, as well as on the association of each health-related endpoint with extrapolated initial and current serum dioxin levels. Findings in this report reveal a consistent relationship between dioxin and body fat that was initially noted in the analysis of the 1987 examination results. Cholesterol and the cholesterol to HDL ratio were found to be associated with current serum dioxin levels. Evidence for a possible association between glucose intolerance, impaired insulin production, and dioxin exposure was revealed, but cause and effect remain to be established. Also revealed was a significant association between selected peripheral pulses and dioxin exposure, and a significant difference in self-perceived health status between Ranch Hands and Comparisons (although possible due to bias). Other health endpoints revealed no consistent patterns within or across clinical areas that were suggestive of health detriment due to dioxin exposure.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume I: 1997 Follow-up Examination Results by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Volume I: 1997 Follow-up Examination Results written by and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report summarizes results from the Air Force Health Study (AFHS). The AFHS is an epidemiological study to determine whether adverse health effects attributable to exposure to herbicides exist in veterans of Operation Ranch Hand Operation. Ranch Hand was the unit responsible for the aerial spraying of herbicides, including Herbicide Orange, in Vietnam from 1961 to 1971. A Comparison cohort comprised Air Force veterans who served in Southeast Asia during the same time period that the Ranch Hand unit was active and who were not involved with spraying herbicides. The summarized data were collected during a physical examination administered between May 1997 and April l998. Of 1,149 eligible Ranch Hands, 870 (73.7%) participated and of 1,761 eligible Comparisons, 1,151(71.0%) participated. Statistical analyses assessed differences between Ranch Hands and Comparisons and associations between health-related endpoints and extrapolated initial dioxin, dioxin exposure category (Comparisons, background Ranch Hands, low Ranch Hands, high Ranch Hands), and dioxin measured in 1987. The study has insufficient statistical power to assess increases in the risk of rare diseases, such as soft tissue sarcoma. Diabetes and cardiovascular abnormalities represent the most important dioxin related health problems seen. From a public health perspective, these two areas demand the greatest attention.
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides by : Joel E. Michalek
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides written by Joel E. Michalek and published by . This book was released on 1998 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update - 1989 by :
Download or read book An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Mortality Update - 1989 written by and published by . This book was released on 1989 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the Air Force Health Study is to determine whether those individuals involved in the spraying of herbicides in Vietnam during the Ranch Hand operation have experienced any adverse health effects as a result of their participation in that program. The study is designed to evaluate both the mortality (death) and morbidity (disease) in these individuals over a 20-year period beginning in 1982. The Baseline Mortality Report was released in June 1983, the Baseline Morbidity Report in February 1984. Follow-up mortality reports were released in 1984, 1985, and 1986. This study has not demonstrated health effects which can be conclusively attributed the overall cumulative mortality of the Ranch Hands remains statistically indistinguishable from that of both their matched Comparisons and the entire Comparison population, although there is a statistically significant increasing trend in post-1983 death rates among Ranch Hand flying officers and statistically significant increase in Ranch hand digestive system deaths relative to the Comparison population; These findings are not suggestive of a herbicide effect. Ranch Hands are equivalent to all Comparisons in cumulative accidental malignant neoplasm and circulatory system mortality. Keywords: Epidemiology, Toxicity.
Book Synopsis Veterans and Agent Orange by : Institute of Medicine
Download or read book Veterans and Agent Orange written by Institute of Medicine and published by National Academies Press. This book was released on 2000-10-30 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the concerns voiced by Vietnam veterans and their families, Congress called upon the National Academy of Sciences (NAS) to review the scientific evidence on the possible health effects of exposure to Agent Orange and other herbicides. This call resulted in the creation of the first NAS Institute of Medicine Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides in 1992. The committee published its initial findings in the 1994 report Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam. This report is the result of a 1999 request from the Department of Veterans Affairs (DVA) under the aegis of the Veterans and Agent Orange research program. Specifically, DVA asked the committee to examine evidence regarding the association, if any, between Type 2 diabetes and exposure to dioxin and other chemical compounds in herbicides used in Vietnam. Veterans and Agent Orange: Herbicide/Dioxin Exposure and Type 2 Diabetes reviews the scientific evidence regarding the association, if any, between Type 2 diabetes1 and exposure to dioxin2 and other chemical compounds in herbicides used in Vietnam. This report examines, to the extent that available data permitted meaningful determinations, (1) whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiologic methods used to detect the association; (2) the increased risk of the disease among those exposed to herbicides during Vietnam service; and (3) whether there is a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease.
