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Author : Antonios G. Kanaras
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (591 download)
Download or read book Enzymatic Manipulation of DNA/gold Nanoparticle Assemblies written by Antonios G. Kanaras and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Timur Kotlyar
Publisher :
ISBN 13 :
Total Pages : 82 pages
Book Rating : 4.:/5 (11 download)
Download or read book DNA-mediated Assembly of Gold Nanoparticles and Restriction Enzyme Induced Disassembly written by Timur Kotlyar and published by . This book was released on 2011 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kyrylo Zagorovsky
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (133 download)
Download or read book DNA-mediated Gold Nanoparticle Assembly written by Kyrylo Zagorovsky and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique physicochemical properties of nanomaterials offer novel methodologies for disease treatment and diagnosis. Dynamic nanoparticle assemblies are adding an additional level of functionality and flexibility by combining multiple nanoparticle types into structures with stimuli-responsive size and surface chemistry. DNA-mediated gold nanoparticles assemblies are offering the most functional and versatile platform, which combines DNA addressability with large surface area, monodispersity, and easy functionalization of gold nanoparticles. Assembly size determines their application, with smaller nanoassemblies particularly suitable for drug delivery, and larger microassemblies used for biosensing. Despite a number of published studies, no in vivo examples or clinically ready biosensors have been reported. Therefore, the goal of this thesis was to identify the barriers for translation in both fields and to develop methods to overcome these limitations. To this end core-satellite nanoassemblies were designed for in vivo delivery, which efficiently protected loaded cargo and minimized macrophage recognition. Their controllable serum stability could be used as the mechanism of cargo release. In vivo nanoassemblies showed longer circulation half-life, improved tumour targeting, and renal bioelimination. In parallel, larger microassembly structures were combined with DNA enzyme signal amplification to generate a novel infectious pathogen biosensor. The assay was particularly suited for point-of-care setting with cheap and stable components and simple, fast, and specific colourimetric readout that could assay multiple targets in parallel. To demonstrate its clinical readiness, the assay was adapted for detection of a panel of five urinary tract infection bacteria. All targets were successfully identified in parallel at clinically relevant concentrations. Preliminary tests with E. coli patient samples confirmed clinical detection with good sensitivity and excellent specificity. This work presents a novel DNA-mediated gold nanoparticle assembly platform that is ready for in vivo translation and clinical in vitro diagnostics.
Author : Johanna Jennifer Justine Midelet
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (11 download)
Download or read book Synthesis and Physicochemical Properties of Programmed DNA-gold Nanoparticle Assemblies written by Johanna Jennifer Justine Midelet and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Johanna Midelet
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (131 download)
Download or read book Synthesis and Physicochemical Properties of Programmed DNA-gold Nanoparticle Assemblies written by Johanna Midelet and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shelley Ann Claridge
Publisher :
ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.:/5 (34 download)
Download or read book Nanocrystal Bioassembly written by Shelley Ann Claridge and published by . This book was released on 2008 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nicholas A. Kotov
Publisher : CRC Press
ISBN 13 : 1420027883
Total Pages : 648 pages
Book Rating : 4.4/5 (2 download)
Download or read book Nanoparticle Assemblies and Superstructures written by Nicholas A. Kotov and published by CRC Press. This book was released on 2016-04-19 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cubes, triangular prisms, nano-acorn, nano-centipedes, nanoshells, nano-whiskers. . . . Now that we can create nanoparticles in a wide variety of shapes and morphologies, comes the next challenge: finding ways to organize this collection of particles into larger and more complex systems. Nanoparticle Assemblies and Superstructures, edit
Author :
Publisher : Academic Press
ISBN 13 : 0123751772
Total Pages : 307 pages
Book Rating : 4.1/5 (237 download)
Download or read book Handbook of Nanofabrication written by and published by Academic Press. This book was released on 2010-05-25 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the devices and systems used in modern industry are becoming progressively smaller and have reached the nanoscale domain. Nanofabrication aims at building nanoscale structures, which can act as components, devices, or systems, in large quantities at potentially low cost. Nanofabrication is vital to all nanotechnology fields, especially for the realization of nanotechnology that involves the traditional areas across engineering and science. - Includes chapters covering the most important Nanofabrication techniques, which aids comprehensive understanding of the latest manufacturing technologies encountered in the field of nano-level manufacturing which is essential for preparing for advanced study and application in nanofabrication techniques by enabling thorough understanding of the entire nanofabrication process as it applies to advanced electronic and related manufacturing technologies - Each chapter covers a nanofabrication technique comprehensively, which allows the reader to learn to produce nanometer-level products as well as collect, process, and analyze data, improve process parameters, and how to assist engineers in research, development and manufacture of the same - Includes contributions from recognized experts from around the globe, making the reader aware of variations in similar techniques applied in different geographical locations and is better positioned to establish all possible global applications
Author :
Publisher :
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.X/5 (4 download)
Download or read book Nanoparticle Assemblies, University of Liverpool, July 14-16, 2003 written by and published by . This book was released on 2003 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jennifer J. McManus
Publisher : Humana
ISBN 13 : 9781493996803
Total Pages : 266 pages
Book Rating : 4.9/5 (968 download)
Download or read book Protein Self-Assembly written by Jennifer J. McManus and published by Humana. This book was released on 2020-08-08 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
Author :
Publisher : Academic Press
ISBN 13 : 0123743966
Total Pages : 2785 pages
Book Rating : 4.1/5 (237 download)
Download or read book Comprehensive Nanoscience and Technology written by and published by Academic Press. This book was released on 2010-10-29 with total page 2785 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Introduction: Nanotechnology and its underpinning sciences are progressing with unprecedented rapidity. With technical advances in a variety of nanoscale fabrication and manipulation technologies, the whole topical area is maturing into a vibrant field that is generating new scientific research and a burgeoning range of commercial applications, with an annual market already at the trillion dollar threshold. The means of fabricating and controlling matter on the nanoscale afford striking and unprecedented opportunities to exploit a variety of exotic phenomena such as quantum, nanophotonic and nanoelectromechanical effects. Moreover, researchers are elucidating new perspectives on the electronic and optical properties of matter because of the way that nanoscale materials bridge the disparate theories describing molecules and bulk matter. Surface phenomena also gain a greatly increased significance; even the well-known link between chemical reactivity and surface-to-volume ratio becomes a major determinant of physical properties, when it operates over nanoscale dimensions. Against this background, this comprehensive work is designed to address the need for a dynamic, authoritative and readily accessible source of information, capturing the full breadth of the subject. Its six volumes, covering a broad spectrum of disciplines including material sciences, chemistry, physics and life sciences, have been written and edited by an outstanding team of international experts. Addressing an extensive, cross-disciplinary audience, each chapter aims to cover key developments in a scholarly, readable and critical style, providing an indispensible first point of entry to the literature for scientists and technologists from interdisciplinary fields. The work focuses on the major classes of nanomaterials in terms of their synthesis, structure and applications, reviewing nanomaterials and their respective technologies in well-structured and comprehensive articles with extensive cross-references. It has been a constant surprise and delight to have found, amongst the rapidly escalating number who work in nanoscience and technology, so many highly esteemed authors willing to contribute. Sharing our anticipation of a major addition to the literature, they have also captured the excitement of the field itself in each carefully crafted chapter. Along with our painstaking and meticulous volume editors, full credit for the success of this enterprise must go to these individuals, together with our thanks for (largely) adhering to the given deadlines. Lastly, we record our sincere thanks and appreciation for the skills and professionalism of the numerous Elsevier staff who have been involved in this project, notably Fiona Geraghty, Megan Palmer and Greg Harris, and especially Donna De Weerd-Wilson who has steered it through from its inception. We have greatly enjoyed working with them all, as we have with each other.
Author : Ulrich Zimmermann
Publisher : CRC Press
ISBN 13 : 9780849344763
Total Pages : 422 pages
Book Rating : 4.3/5 (447 download)
Download or read book Electromanipulation of Cells written by Ulrich Zimmermann and published by CRC Press. This book was released on 1996-02-16 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electromanipulation of Cells is the first comprehensive, balanced overview of this dynamic discipline. Edited by leading authorities in the field, the book surveys state-of-the-art research as well as recent practical applications of electric field technologies.
Author : Ehud Gazit
Publisher : Springer Science & Business Media
ISBN 13 : 9781934115350
Total Pages : 296 pages
Book Rating : 4.1/5 (153 download)
Download or read book Nanostructure Design written by Ehud Gazit and published by Springer Science & Business Media. This book was released on 2008-08-05 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: As one of the fastest growing fields of research in the 21st century, nanotechnology is sure to have an enormous impact on many aspects of our lives. Nanostructure Design: Methods and Protocols serves as a major reference for theoretical and experimental considerations in the design of biological and bio-inspired building blocks, the physical characterization of the formed structures, and the development of their technical applications. The chapters contributed by leading experts are divided into two sections, the first of which covers experimental aspects of nanostructure design and the second delves into computational methods. As a volume of the highly successful Methods in Molecular BiologyTM series, this collection pulls together cutting-edge protocols, written in a step-by-step, readily reproducible format certain to guide researchers to the desired results. Comprehensive and essential, Nanostructure Design: Methods and Protocols uses biological principles and vehicles on design to aid scientists in the great challenges still ahead.
Author : Xiao-Hong Nancy Xu
Publisher : John Wiley & Sons
ISBN 13 : 0470119497
Total Pages : 338 pages
Book Rating : 4.4/5 (71 download)
Download or read book New Frontiers in Ultrasensitive Bioanalysis written by Xiao-Hong Nancy Xu and published by John Wiley & Sons. This book was released on 2007-06-04 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of current research and developments in ultrasensitive bioanalysis New platforms of ultrasensitive analysis of biomolecules and single living cells using multiplexing, single nanoparticle sensing, nano-fluidics, and single-molecule detection are advancing every scientific discipline at an unprecedented pace. With chapters written by a diverse group of scientists working in the forefront of ultrasensitive bioanalysis, this book provides an overview of the current status and an in-depth understanding of the objectives and future research directions of ultrasensitive bioanalysis. Spanning a wide spectrum of new research approaches, this book: Introduces new theories, ideas, methodologies, technologies, and applications of ultrasensitive bioanalysis in a wide variety of research fields Includes background, fundamentals, and descriptions of instrumentation and techniques behind every experimental design and approach to help readers explore the promising applications of new tools Covers single molecule detection (SMD), single living cell analysis, multi-functional nanoparticle probes, miniaturization, multiplexing, quantitative and qualitative analysis of metal ions and small molecules, and more Discusses techniques such as single molecule microscope and spectroscopy, single nanoparticle optics, single nanoparticle sensors, micro- and nano-fluidics, microarray detection, ultramicroelectrodes, electrochemiluminescence, mass spectrometry, and more This book will be a useful resource and an inspiration for scientists and graduate and undergraduate students in a wide variety of research fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering.
Author : Nguyen TK Thanh
Publisher : CRC Press
ISBN 13 : 1439869332
Total Pages : 603 pages
Book Rating : 4.4/5 (398 download)
Download or read book Magnetic Nanoparticles written by Nguyen TK Thanh and published by CRC Press. This book was released on 2012-02-01 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering the latest information in magnetic nanoparticle (MNP) research, Magnetic Nanoparticles: From Fabrication to Clinical Applications provides a comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers.This book, written by some of the mo
Author : Victor R. Preedy
Publisher : Springer
ISBN 13 : 9789400776951
Total Pages : 0 pages
Book Rating : 4.7/5 (769 download)
Download or read book General Methods in Biomarker Research and their Applications written by Victor R. Preedy and published by Springer. This book was released on 2015-08-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics and so on. The chapters are written by national or international experts and specialists.
Author :
Publisher :
ISBN 13 :
Total Pages : 998 pages
Book Rating : 4.F/5 ( download)
Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2005 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theses on any subject submitted by the academic libraries in the UK and Ireland.
