Toxicity Testing in the 21st Century

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Author :
Publisher : National Academies Press
ISBN 13 : 0309109922
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing in the 21st Century by : National Research Council

Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

Toxicity Testing for Assessment of Environmental Agents

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Author :
Publisher : National Academies Press
ISBN 13 : 0309164869
Total Pages : 270 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing for Assessment of Environmental Agents by : National Research Council

Download or read book Toxicity Testing for Assessment of Environmental Agents written by National Research Council and published by National Academies Press. This book was released on 2006-04-07 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.

Environmental Toxicity Testing

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 140514470X
Total Pages : 408 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Environmental Toxicity Testing by : K. Clive Thompson

Download or read book Environmental Toxicity Testing written by K. Clive Thompson and published by John Wiley & Sons. This book was released on 2009-02-05 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: As an integral component of environmental policy, it has become essential to regulate and monitor toxic substances. Past emphasis has been primarily on analytical approaches to the detection of specific, targeted contaminants, thus allowing chemical characterisation. However, toxicity testing or biological assessment is necessary for ecotoxicological evaluation, and this offers marked benefits and advantages that complement chemical analysis. Key issues to be addressed include identification of pertinent tests, reproducibility and robustness of these tests, and cost considerations.This book examines these issues and describes and explains the approaches that have been developed for environmental toxicity evaluations. Advantages, benefits and drawbacks of the strategies and methods are highlighted. Directed equally at ecotoxicologists, industrial chemists, analytical chemists and environmental consultants, this book is written in a way that will prove helpful to both new and experienced practitioners.

Toxicity Testing for Assessment of Environmental Agents

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Author :
Publisher : National Academies Press
ISBN 13 : 0309100925
Total Pages : 271 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing for Assessment of Environmental Agents by : National Research Council

Download or read book Toxicity Testing for Assessment of Environmental Agents written by National Research Council and published by National Academies Press. This book was released on 2006-05-07 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.

Short-term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms

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Author :
Publisher :
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Short-term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms by :

Download or read book Short-term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms written by and published by . This book was released on 1994 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods for Acute Toxicity Tests with Fish, Macroinvertebrates, and Amphibians

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Publisher :
ISBN 13 :
Total Pages : 82 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Methods for Acute Toxicity Tests with Fish, Macroinvertebrates, and Amphibians by : Committee on Methods for Toxicity Tests with Aquatic Organisms

Download or read book Methods for Acute Toxicity Tests with Fish, Macroinvertebrates, and Amphibians written by Committee on Methods for Toxicity Tests with Aquatic Organisms and published by . This book was released on 1975 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods for Measuring the Acute Toxicity of Effluents and Receiving Waters to Freshwater and Marine Organisms

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Author :
Publisher : DIANE Publishing
ISBN 13 : 1428905375
Total Pages : 275 pages
Book Rating : 4.4/5 (289 download)

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Book Synopsis Methods for Measuring the Acute Toxicity of Effluents and Receiving Waters to Freshwater and Marine Organisms by :

Download or read book Methods for Measuring the Acute Toxicity of Effluents and Receiving Waters to Freshwater and Marine Organisms written by and published by DIANE Publishing. This book was released on 2002 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Soil Invertebrate Toxicity Tests

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Author :
Publisher :
ISBN 13 :
Total Pages : 316 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook of Soil Invertebrate Toxicity Tests by : Hans Løkke

Download or read book Handbook of Soil Invertebrate Toxicity Tests written by Hans Løkke and published by . This book was released on 1998 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive user guide to toxicity testing which provides readily accessible information on the results of terrestrial invertebrate testing. Presenting guidelines for the application of new test systems for soil ecotoxicity testing, this unique book also includes standard operating procedures and specialist protocols.

Fundamentals Of Aquatic Toxicology

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Publisher : CRC Press
ISBN 13 : 100016294X
Total Pages : 1152 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Fundamentals Of Aquatic Toxicology by : Gary M. Rand

Download or read book Fundamentals Of Aquatic Toxicology written by Gary M. Rand and published by CRC Press. This book was released on 2020-08-06 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.

An Introduction to Aquatic Toxicology

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Author :
Publisher : Elsevier
ISBN 13 : 0124115810
Total Pages : 253 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis An Introduction to Aquatic Toxicology by : Mikko Nikinmaa

Download or read book An Introduction to Aquatic Toxicology written by Mikko Nikinmaa and published by Elsevier. This book was released on 2014-07-01 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field. Provides with the latest perspectives on the impacts of toxicants on aquatic environments, such as nanotoxicology, toxicogenomics, ocean acidification and eutrophication Offers a complete overview, beginning with the origins of aquatic toxicology and concluding with potential future challenges Includes guidance on testing methods and a glossary of aquatic toxicology terms

Methods for Measuring the Toxicity and Bioaccumulation of Sediment-associated Contaminants with Freshwater Invertebrates

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Author :
Publisher :
ISBN 13 :
Total Pages : 220 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Methods for Measuring the Toxicity and Bioaccumulation of Sediment-associated Contaminants with Freshwater Invertebrates by :

Download or read book Methods for Measuring the Toxicity and Bioaccumulation of Sediment-associated Contaminants with Freshwater Invertebrates written by and published by . This book was released on 2000 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods for Assessing the Toxicity of Sediment-associated Contaminants with Estuarine and Marine Amphipods

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Author :
Publisher :
ISBN 13 :
Total Pages : 158 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Methods for Assessing the Toxicity of Sediment-associated Contaminants with Estuarine and Marine Amphipods by :

Download or read book Methods for Assessing the Toxicity of Sediment-associated Contaminants with Estuarine and Marine Amphipods written by and published by . This book was released on 1994 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Neurotoxicology

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Publisher : National Academies Press
ISBN 13 : 0309045312
Total Pages : 167 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Environmental Neurotoxicology by : National Research Council

Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Handbook of Acute Toxicity of Chemicals to Fish and Aquatic Invertebrates

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Author :
Publisher :
ISBN 13 :
Total Pages : 106 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook of Acute Toxicity of Chemicals to Fish and Aquatic Invertebrates by : W. Waynon Johnson

Download or read book Handbook of Acute Toxicity of Chemicals to Fish and Aquatic Invertebrates written by W. Waynon Johnson and published by . This book was released on 1980 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Use of Dispersants in Marine Oil Spill Response

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Publisher : National Academies Press
ISBN 13 : 0309478219
Total Pages : 341 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Use of Dispersants in Marine Oil Spill Response by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Use of Dispersants in Marine Oil Spill Response written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-04-24 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whether the result of an oil well blowout, vessel collision or grounding, leaking pipeline, or other incident at sea, each marine oil spill will present unique circumstances and challenges. The oil type and properties, location, time of year, duration of spill, water depth, environmental conditions, affected biomes, potential human community impact, and available resources may vary significantly. Also, each spill may be governed by policy guidelines, such as those set forth in the National Response Plan, Regional Response Plans, or Area Contingency Plans. To respond effectively to the specific conditions presented during an oil spill, spill responders have used a variety of response optionsâ€"including mechanical recovery of oil using skimmers and booms, in situ burning of oil, monitored natural attenuation of oil, and dispersion of oil by chemical dispersants. Because each response method has advantages and disadvantages, it is important to understand specific scenarios where a net benefit may be achieved by using a particular tool or combination of tools. This report builds on two previous National Research Council reports on dispersant use to provide a current understanding of the state of science and to inform future marine oil spill response operations. The response to the 2010 Deepwater Horizon spill included an unprecedented use of dispersants via both surface application and subsea injection. The magnitude of the spill stimulated interest and funding for research on oil spill response, and dispersant use in particular. This study assesses the effects and efficacy of dispersants as an oil spill response tool and evaluates trade-offs associated with dispersant use.

Measures of Environmental Performance and Ecosystem Condition

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Publisher : National Academies Press
ISBN 13 : 0309522331
Total Pages : 309 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Measures of Environmental Performance and Ecosystem Condition by : National Academy of Engineering

Download or read book Measures of Environmental Performance and Ecosystem Condition written by National Academy of Engineering and published by National Academies Press. This book was released on 1999-06-02 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Cleveland's Cuyahoga River caught fire in 1969, no environmental measurements were necessary to know the seriousness of the problem. Incidents like the Cuyahoga fire raise an important question: Can catastrophes-in-the-making be detected early enough to be prevented? For those in industry, such disasters point to the need for measures that can improve the environmental performance of processes, products, business practices, and linked industrial systems. In Measures of Environmental Performance and Ecosystem Condition, experts share their insights on environmental metrics. The volume explores the most productive relationship between measures of environmental performance and measures of ecosystem conditions. It reviews current approaches, evaluates structures for business decisionmaking, and includes a matrix for determining the environmental performance of industrial facilities. Case studies include: Development and application of a water-quality rating scheme for streams and reservoirs in the Tennessee Valley. Three years of successful experience with waste metrics at 3M. The book covers the range of environmental performance and condition metrics, from the use of material flow data to monitor environmental performance at the national level to the use of bioassays to measure the toxicity of industrial effluents. This book offers something for everyone--policymakers, executives, engineers, managers, and advocates--with a stake in the measurement of environmental performance and ecological conditions.

Science and Judgment in Risk Assessment

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Publisher : National Academies Press
ISBN 13 : 030904894X
Total Pages : 668 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Science and Judgment in Risk Assessment by : National Research Council

Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.