Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Emerging Diseases As Complex Adaptive Systems Pilot
Download Emerging Diseases As Complex Adaptive Systems Pilot full books in PDF, epub, and Kindle. Read online Emerging Diseases As Complex Adaptive Systems Pilot ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Emerging Diseases as Complex Adaptive Systems/Pilot by : John Grefenstette
Download or read book Emerging Diseases as Complex Adaptive Systems/Pilot written by John Grefenstette and published by . This book was released on 1997 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: We designed and tested a computational model of emerging viruses that simulates the evolution of real biological viruses. Knowledge of viral molecular replication mechanisms was used to instruct the development of this genetic algorithm-based C language 'Virtual Virus' (vW). The model consists of populations of hundreds to thousands of variable length virtual virus genomes that replicate, mutate, recombine, and evolve. Each virus genome is composed of an artificial polynucleotide string in which arbitrary 'nucleotide' triplets encode English letters rather than amino acids, and in which sequences are translated into words or phrases, rather than into polypeptides or proteins. The three word/phrases 'COREPROThIN, ' 'POLY- MERASE, ' and 'ENVELOPE, ' which can be present in any order on the string, together comprise the selected phenotype. Run-on and overlapping reading frames are permitted. Fitness is assigned to each string according to the encoded spelling score. Probability of replication at each generation is directly related to string fitness. VIV populations seeded with random strings regularly evolve terse, high spelling score genomes within a few hundred to a thousand generations. By systematically varying evolutionary operators in the VIV model we observed several reproducible features relevant to the evolution and emergence of biological viruses: (1) adaptation (fitness slope) proceeds most rapidly at mutation rates close to one per genome, and falls off rapidly at rates either higher or lower than unity (2) when added to mutation, recombination in any form speeds adaptation, and (3) homologous recombination is superior to random cross-over recombination.
Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes
Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Download or read book Behind the numbers written by UNESCO and published by UNESCO Publishing. This book was released on 2019-01-31 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Emerging Viral Diseases by : Institute of Medicine
Download or read book Emerging Viral Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.
Book Synopsis Emerging Infectious Diseases from the Global to the Local Perspective by : Institute of Medicine
Download or read book Emerging Infectious Diseases from the Global to the Local Perspective written by Institute of Medicine and published by National Academies Press. This book was released on 2001-03-29 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: In October 1999, the Forum on Emerging Infections of the Institute of Medicine convened a two-day workshop titled "International Aspects of Emerging Infections." Key representatives from the international community explored the forces that drive emerging infectious diseases to prominence. Representatives from the Americas, Africa, Asia and the Pacific, and Europe made formal presentations and engaged in panel discussions. Emerging Infectious Diseases from the Global to the Local Perspective includes summaries of the formal presentations and suggests an agenda for future action. The topics addressed cover a wide range of issues, including trends in the incidence of infectious diseases around the world, descriptions of the wide variety of factors that contribute to the emergence and reemergence of these diseases, efforts to coordinate surveillance activities and responses within and across borders, and the resource, research, and international needs that remain to be addressed.
Download or read book Human Monkeypox written by and published by . This book was released on 1988 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Evidence-Based Medicine and the Changing Nature of Health Care by : Institute of Medicine
Download or read book Evidence-Based Medicine and the Changing Nature of Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2008-09-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.
Book Synopsis Unraveling the Mystery of Health by : Aaron Antonovsky
Download or read book Unraveling the Mystery of Health written by Aaron Antonovsky and published by Jossey-Bass. This book was released on 1987-02-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antonovsky's book challenges the health care community to reassess its approach to health. He asserts that the focus for too long has been solely on illness and the treatment of specific disease, with little or no attention directed at the factors and conditions necessary for health. The author offers a way to evaluate the psychological, social, and cultural factors that relate to health and well-being. Antonovsky presents a model that he calls the ``sense of coherence'' (SOC), suggesting that the way people make sense of the world is a major factor in their health. He provides, as an appendix, a questionnaire for assessing the SOC for individuals to evaluate and predict how well they manage stress and stay healthy. This model was presented by Antonovsky in an earlier work, but this volume provides more detail on both the theoretical and research database for the SOC. Insight is provided on how SOC affects neuroendocrine and immunological processes and thus overall health. The conceptual framework presented in this book is useful and important. The writing style, however, is often cumbersome, making for difficult reading. In addition, the author assumes readers are familiar with his earlier work, Health, Stress and Coping (CH, Jan '80); readers not acquainted with its content will find it difficult to follow the ideas being presented. In spite of these shortcomings, the book sets an important direction for thought in the evolution of health promotion strategies.
Author :National Academy of Engineering Publisher :National Academies Press ISBN 13 :0309120640 Total Pages :340 pages Book Rating :4.3/5 (91 download)
Book Synopsis Engineering a Learning Healthcare System by : National Academy of Engineering
Download or read book Engineering a Learning Healthcare System written by National Academy of Engineering and published by National Academies Press. This book was released on 2011-07-14 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving our nation's healthcare system is a challenge which, because of its scale and complexity, requires a creative approach and input from many different fields of expertise. Lessons from engineering have the potential to improve both the efficiency and quality of healthcare delivery. The fundamental notion of a high-performing healthcare system-one that increasingly is more effective, more efficient, safer, and higher quality-is rooted in continuous improvement principles that medicine shares with engineering. As part of its Learning Health System series of workshops, the Institute of Medicine's Roundtable on Value and Science-Driven Health Care and the National Academy of Engineering, hosted a workshop on lessons from systems and operations engineering that could be applied to health care. Building on previous work done in this area the workshop convened leading engineering practitioners, health professionals, and scholars to explore how the field might learn from and apply systems engineering principles in the design of a learning healthcare system. Engineering a Learning Healthcare System: A Look at the Future: Workshop Summary focuses on current major healthcare system challenges and what the field of engineering has to offer in the redesign of the system toward a learning healthcare system.
Book Synopsis Systems Thinking in Medicine and New Drug Discovery by : Robert E. Smith
Download or read book Systems Thinking in Medicine and New Drug Discovery written by Robert E. Smith and published by Cambridge Scholars Publishing. This book was released on 2018-12-17 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Total Quality Management (TQM) and systems thinking are being used to improve all aspects of human health. This first book in a two-volume set details how the healthcare community is working with patients and their caregivers to improve healthcare and reduce its costs. Systems-based thinking encourages us to work together to look at the effects of new drugs on entire systems and not just single molecular targets. It also leads us to a better understanding of genetics and epigenetics, as well as the deep ecology of the human body. The healthcare community is developing targeted therapies that stimulate our own bodies to cure ourselves and eliminate the need for animal testing. This book will appeal to specialists, who will find recommendations on safer materials for 3D bioprinting and ways to analyze dietary supplements for toxic contaminants, and physicians, pharmacists and non-professionals, who will learn the important different ways that dietary supplements and prescription drugs are developed, sold and marketed.
Book Synopsis The Essence Of Chaos by : Flavio Lorenzelli
Download or read book The Essence Of Chaos written by Flavio Lorenzelli and published by CRC Press. This book was released on 2003-09-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of chaotic systems has become a major scientific pursuit in recent years, shedding light on the apparently random behaviour observed in fields as diverse as climatology and mechanics. InThe Essence of Chaos Edward Lorenz, one of the founding fathers of Chaos and the originator of its seminal concept of the Butterfly Effect, presents his own landscape of our current understanding of the field. Lorenz presents everyday examples of chaotic behaviour, such as the toss of a coin, the pinball's path, the fall of a leaf, and explains in elementary mathematical strms how their essentially chaotic nature can be understood. His principal example involved the construction of a model of a board sliding down a ski slope. Through this model Lorenz illustrates chaotic phenomena and the related concepts of bifurcation and strange attractors. He also provides the context in which chaos can be related to the similarly emergent fields of nonlinearity, complexity and fractals. As an early pioneer of chaos, Lorenz also provides his own story of the human endeavour in developing this new field. He describes his initial encounters with chaos through his study of climate and introduces many of the personalities who contributed early breakthroughs. His seminal paper, "Does the Flap of a Butterfly's Wing in Brazil Set Off a Tornado in Texas?" is published for the first time.
Book Synopsis Practical Human Factors for Pilots by : Capt. David Moriarty
Download or read book Practical Human Factors for Pilots written by Capt. David Moriarty and published by Academic Press. This book was released on 2014-12-30 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Human Factors for Pilots bridges the divide between human factors research and one of the key industries that this research is meant to benefit—civil aviation. Human factors are now recognized as being at the core of aviation safety and the training syllabus that flight crew trainees have to follow reflects that. This book will help student pilots pass exams in human performance and limitations, successfully undergo multi-crew cooperation training and crew resource management (CRM) training, and prepare them for assessment in non-technical skills during operator and license proficiency checks in the simulator, and during line checks when operating flights. Each chapter begins with an explanation of the relevant science behind that particular subject, along with mini-case studies that demonstrate its relevance to commercial flight operations. Of particular focus are practical tools and techniques that students can learn in order to improve their performance as well as "training tips" for the instructor. Provides practical, evidence-based guidance on issues often at the root of aircraft accidents Uses international regulatory material Includes concepts and theories that have practical relevance to flight operations Covers relevant topics in a step-by-step manner, describing how they apply to flight operations Demonstrates how human decision-making has been implicated in air accidents and equips the reader with tools to mitigate these risks Gives instructors a reliable knowledge base on which to design and deliver effective training Summarizes the current state of human factors, training, and assessment
Book Synopsis Improving Food Safety Through a One Health Approach by : Institute of Medicine
Download or read book Improving Food Safety Through a One Health Approach written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-10 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.
Book Synopsis The Problem with Pilots by : Timothy P. Schultz
Download or read book The Problem with Pilots written by Timothy P. Schultz and published by JHU Press. This book was released on 2018-03-15 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction -- The pathology of flight -- Engineering the human machine -- Flying blind -- The changing role of the human component -- Flight without flyers -- The modern pilot, redefined -- New horizons of flight -- Conclusion: the past and future of pilots
Book Synopsis Crossing the Quality Chasm by : Institute of Medicine
Download or read book Crossing the Quality Chasm written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-19 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second in a series of publications from the Institute of Medicine's Quality of Health Care in America project Today's health care providers have more research findings and more technology available to them than ever before. Yet recent reports have raised serious doubts about the quality of health care in America. Crossing the Quality Chasm makes an urgent call for fundamental change to close the quality gap. This book recommends a sweeping redesign of the American health care system and provides overarching principles for specific direction for policymakers, health care leaders, clinicians, regulators, purchasers, and others. In this comprehensive volume the committee offers: A set of performance expectations for the 21st century health care system. A set of 10 new rules to guide patient-clinician relationships. A suggested organizing framework to better align the incentives inherent in payment and accountability with improvements in quality. Key steps to promote evidence-based practice and strengthen clinical information systems. Analyzing health care organizations as complex systems, Crossing the Quality Chasm also documents the causes of the quality gap, identifies current practices that impede quality care, and explores how systems approaches can be used to implement change.
Download or read book Complexity written by M. Mitchell Waldrop and published by Open Road Media. This book was released on 2019-10-01 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: “If you liked Chaos, you’ll love Complexity. Waldrop creates the most exciting intellectual adventure story of the year” (The Washington Post). In a rarified world of scientific research, a revolution has been brewing. Its activists are not anarchists, but rather Nobel Laureates in physics and economics and pony-tailed graduates, mathematicians, and computer scientists from all over the world. They have formed an iconoclastic think-tank and their radical idea is to create a new science: complexity. They want to know how a primordial soup of simple molecules managed to turn itself into the first living cell—and what the origin of life some four billion years ago can tell us about the process of technological innovation today. This book is their story—the story of how they have tried to forge what they like to call the science of the twenty-first century. “Lucidly shows physicists, biologists, computer scientists and economists swapping metaphors and reveling in the sense that epochal discoveries are just around the corner . . . [Waldrop] has a special talent for relaying the exhilaration of moments of intellectual insight.” —The New York Times Book Review “Where I enjoyed the book was when it dove into the actual question of complexity, talking about complex systems in economics, biology, genetics, computer modeling, and so on. Snippets of rare beauty here and there almost took your breath away.” —Medium “[Waldrop] provides a good grounding of what may indeed be the first flowering of a new science.” —Publishers Weekly
Book Synopsis Adaptive Leadership: The Heifetz Collection (3 Items) by : Ronald A. Heifetz
Download or read book Adaptive Leadership: The Heifetz Collection (3 Items) written by Ronald A. Heifetz and published by Harvard Business Review Press. This book was released on 2014-09-23 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: In times of constant change, adaptive leadership is critical. This Harvard Business Review collection brings together the seminal ideas on how to adapt and thrive in challenging environments, from leading thinkers on the topic—most notably Ronald A. Heifetz of the Harvard Kennedy School and Cambridge Leadership Associates. The Heifetz Collection includes two classic books: Leadership on the Line, by Ron Heifetz and Marty Linsky, and The Practice of Adaptive Leadership, by Heifetz, Linsky, and Alexander Grashow. Also included is the popular Harvard Business Review article, “Leadership in a (Permanent) Crisis,” written by all three authors. Available together for the first time, this collection includes full digital editions of each work. Adaptive leadership is a practical framework for dealing with today’s mix of urgency, high stakes, and uncertainty. It has been used by individuals, organizations, businesses, and governments worldwide. In a world of challenging environments, adaptive leadership serves as a guide to distinguishing the essential from the expendable, beginning the meaningful process of adaption, and changing the status quo. Ronald A. Heifetz is a cofounder of the international leadership and consulting practice Cambridge Leadership Associates (CLA) and the founding director of the Center for Public Leadership at the Harvard Kennedy School. He is renowned worldwide for his innovative work on the practice and teaching of leadership. Marty Linsky is a cofounder of CLA and has taught at the Kennedy School for more than twenty-five years. Alexander Grashow is a Senior Advisor to CLA, having previously held the position of CEO.
