Elizabeth Blackburn And The Story Of Telomeres

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Elizabeth Blackburn and the Story of Telomeres

Author : Catherine Brady
Publisher : MIT Press
ISBN 13 : 0262261960
Total Pages : 405 pages
Book Rating : 4.2/5 (622 download)

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Book Synopsis Elizabeth Blackburn and the Story of Telomeres by : Catherine Brady

Download or read book Elizabeth Blackburn and the Story of Telomeres written by Catherine Brady and published by MIT Press. This book was released on 2009-02-13 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of molecular biologist Elizabeth Blackburn and her groundbreaking research on telomeres and what it reveals about the resourceful opportunism that characterizes the best scientific thinking. Molecular biologist Elizabeth Blackburn—one of Time magazine's 100 “Most Influential People in the World” in 2007—made headlines in 2004 when she was dismissed from the President's Council on Bioethics after objecting to the council's call for a moratorium on stem cell research and protesting the suppression of relevant scientific evidence in its final report. But it is Blackburn's groundbreaking work on telomeric DNA, which launched the field of telomere research, that will have the more profound and long-lasting effect on science and society. In this compelling biography, Catherine Brady tells the story of Elizabeth Blackburn's life and work and the emergence of a new field of scientific research on the specialized ends of chromosomes and the enzyme, telomerase, that extends them. In the early stages of telomere research, telomerase, heralded as a potential cure for cancer and diseases related to aging, attracted the voracious interest of biotech companies. The surrounding hype succeeded in confusing the role of telemorase in extending the life of a cell with a mechanism that might extend the lifespan of an entire organism. In Brady's hands, Blackburn's story reveals much about the tension between pure and applied science, the politicking that makes research science such a competitive field, and the resourceful opportunism that characterizes the best scientific thinking. Brady describes the science accessibly and compellingly. She explores Blackburn's struggle to break down barriers in an elite, male-dominated profession, her role as a mentor to other women scientists (many of whom have made their mark in telomere research), and the collaborative nature of scientific work. This book gives us a vivid portrait of an exceptional woman and a new understanding of the combination of curiosity, imaginative speculation, and aesthetic delight that powers scientific discovery.

The Telomere Effect

Author : Dr. Elizabeth Blackburn
Publisher : Grand Central Publishing
ISBN 13 : 1455587966
Total Pages : 328 pages
Book Rating : 4.4/5 (555 download)

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Book Synopsis The Telomere Effect by : Dr. Elizabeth Blackburn

Download or read book The Telomere Effect written by Dr. Elizabeth Blackburn and published by Grand Central Publishing. This book was released on 2017-01-03 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times bestselling book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). The Telemere Effect reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. The Telemere Effect will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

AARP The Immortality Edge

Author : Michael Fossel
Publisher : John Wiley & Sons
ISBN 13 : 1118370147
Total Pages : 251 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis AARP The Immortality Edge by : Michael Fossel

Download or read book AARP The Immortality Edge written by Michael Fossel and published by John Wiley & Sons. This book was released on 2012-04-23 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: AARP Digital Editions offer you practical tips, proven solutions, and expert guidance. Based on Nobel Prize–winning genetic research, AARP The Immortality Edge provides a simple plan to keep your telomeres healthy for better health and longevity. Telomeres play an important role in protecting our chromosomes from critical damage. The shortening of the telomere disrupts vital cellular function and promotes the previously seemingly inevitable onset of aging and various diseases, including cancer and Alzheimer's. Drawing from the groundbreaking discoveries about telomeres that won the 2009 Nobel Prize in Medicine, this book includes a highly prescriptive program that shows you how to live longer by slowing telomere shortening and rejuvenating your cells through relatively simple alterations in nutrition habits and other lifestyle changes. Written by authors with extensive knowledge of genetics, telomeres, and longevity Offers a simple action plan you can start using immediately Includes a revolutionary new eating plan Recommends individualized supplement programs Shares a diet and exercise approach grounded in solid scientific research The exciting recent discoveries about telomeres promise to revolutionize our approach to anti-aging much as antioxidants did ten years ago. Unlike trendy diet and fitness books with no basis in science, The Immortality Edge targets health at its innermost level by laying out a realistic, lifelong plan using easy steps that can fit into any busy schedule-steps that can improve the length and quality of your life.

Telomere Timebombs

Author : Ed Park
Publisher :
ISBN 13 : 9780989583701
Total Pages : 218 pages
Book Rating : 4.5/5 (837 download)

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Book Synopsis Telomere Timebombs by : Ed Park

Download or read book Telomere Timebombs written by Ed Park and published by . This book was released on 2013-08 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomere Timebombs: Defusing the Terror of Aging showcases a revolutionary new way to think about aging and health. Dr. Ed Park's entertaining and insightful new book introduces readers to Telomeres - repetitive DNA sequences that play a vital role in aging. Telomeres, if kept intact, can afford a lifetime of better sleep, healthier skin, better mood, better exercise recovery time, and even an improved sex life. Life-changing Information For millions, the fear of growing old is in itself enough to force out grey hairs and wrinkles. However, this compelling book presents a wholly-refreshing way to embrace aging and total health. While life-changing, Dr. Park's wisdom is far from complicated. In fact, using entertaining analogies ranging from queen bees to automobile repair, the book is poised to resonate with young and old around the world. Synopsis This fresh, fascinating and often funny book teaches you why we get old and sick and describes the journeys back to health and youth experienced after taking Telomerase Activation Medicine. It outlines a future in which Telomerase Activation Medicine has changed all your expectations about getting old. Dr. Park explains how it works: "Telomeres, or 'end bodies' are the caps that protect our chromosomes like the plastic tips on shoelaces. Each time a cell divides into two daughters, the daughters are left with shorter telomeres. These telomeres caps shorten like burning fuses on the end of a firecracker. When those 'fuses' become too short, the chromosomes are damaged and the cell either stops functioning properly or dies," he says. Continuing, "There is a cure for this erosion called the Telomerase Enzyme, and it is built into every single stem cell in your body. Stem cells are like queen bees that need produce many thousands of worker drones, so a stem cell always needs to add back telomere length to prevent premature damage and death." By keeping the Telomere length as long as possible, the individual can enjoy prolonged vitality, youthfulness and overall health. This is achieved through an ingestible supplement called TA-65, a molecule discovered by scientists to be a Telomerase activator. As one of the first twenty people in the world to trial it and, after noticing astonishing results, Dr. Park became the first medical doctor licensed to prescribe TA-65. Since then, hundreds of physicians and tens of thousands of patients have jumped on board with amazing results and no adverse effects. A Grand Unified Theory of Aging and Disease Dr. Park has developed a simple and intuitive new model of aging based on Telomere erosion and Stem Cell biology that will shift and unify much of the research and efforts currently in vogue. With his renowned knack for presenting his concepts in an engaging and easy-to-understand way, Dr. Park likens it to the on-going upkeep of an automobile. "Why not think of it as car maintenance? You are just changing your oil and replacing old parts. There is a man in New York who has maintained his Volvo for 3 million miles. Is the Volvo Corporation going to strike him down with a lightning bolt? No They love him ," he adds. Those wanting to find out how to embark on their own personal journey back to youthful health by using Telomere Activation Medicine are urged to purchase this book.

Carbon Queen

Author : Maia Weinstock
Publisher : MIT Press
ISBN 13 : 0262545977
Total Pages : 336 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Carbon Queen by : Maia Weinstock

Download or read book Carbon Queen written by Maia Weinstock and published by MIT Press. This book was released on 2023-03-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The life of trailblazing physicist Mildred Dresselhaus, who expanded our understanding of the physical world. As a girl in New York City in the 1940s, Mildred “Millie” Dresselhaus was taught that there were only three career options open to women: secretary, nurse, or teacher. But sneaking into museums, purchasing three-cent copies of National Geographic, and devouring books on the history of science ignited in Dresselhaus (1930–2017) a passion for inquiry. In Carbon Queen, science writer Maia Weinstock describes how, with curiosity and drive, Dresselhaus defied expectations and forged a career as a pioneering scientist and engineer. Dresselhaus made highly influential discoveries about the properties of carbon and other materials and helped reshape our world in countless ways—from electronics to aviation to medicine to energy. She was also a trailblazer for women in STEM and a beloved educator, mentor, and colleague. Her path wasn’t easy. Dresselhaus’s Bronx childhood was impoverished. Her graduate adviser felt educating women was a waste of time. But Dresselhaus persisted, finding mentors in Nobel Prize–winning physicists Rosalyn Yalow and Enrico Fermi. Eventually, Dresselhaus became one of the first female professors at MIT, where she would spend nearly six decades. Weinstock explores the basics of Dresselhaus’s work in carbon nanoscience accessibly and engagingly, describing how she identified key properties of carbon forms, including graphite, buckyballs, nanotubes, and graphene, leading to applications that range from lighter, stronger aircraft to more energy-efficient and flexible electronics.

The Telomerase Revolution

Author : Michael Fossel
Publisher : Atlantic Books Ltd
ISBN 13 : 1782399119
Total Pages : 281 pages
Book Rating : 4.7/5 (823 download)

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Book Synopsis The Telomerase Revolution by : Michael Fossel

Download or read book The Telomerase Revolution written by Michael Fossel and published by Atlantic Books Ltd. This book was released on 2015-10-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science is on the cusp of a revolutionary breakthrough. We now understand more about ageing - and how to prevent and reverse it - than ever before. In The Telomerase Revolution, Dr Michael Fossel, who has been at the cutting edge of ageing research for decades, describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to intervene in age-related disease, dramatically extend life spans and even reverse human ageing. Telomerase-based treatments are already on offer, and have shown early promise, but much more potent treatments will become available over the next decade. This is the definitive work on the latest science of human ageing, covering both the theory and the clinical implications, taking readers to the forefront of one of the most remarkable advances in human medicine.

Einstein's Wife

Author : Allen Esterson
Publisher : MIT Press
ISBN 13 : 0262538970
Total Pages : 337 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Einstein's Wife by : Allen Esterson

Download or read book Einstein's Wife written by Allen Esterson and published by MIT Press. This book was released on 2020-02-25 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: The real-life story behind Marie Benedict’s The Other Einstein—a fascinating profile of mathematician Mileva Einstein-Marić and her contributions to her husband’s scientific discoveries. Albert Einstein’s first wife, Mileva Einstein-Marić, was forgotten for decades. When a trove of correspondence between them beginning in their student days was discovered in 1986, her story began to be told. Some of the tellers of the “Mileva Story” made startling claims: that she was a brilliant mathematician who surpassed her husband, and that she made uncredited contributions to his most celebrated papers in 1905, including his paper on special relativity. This book, based on extensive historical research, uncovers the real “Mileva Story.” Mileva was one of the few women of her era to pursue higher education in science; she and Einstein were students together at the Zurich Polytechnic. Mileva’s ambitions for a science career, however, suffered a series of setbacks—failed diploma examinations, a disagreement with her doctoral dissertation adviser, an out-of-wedlock pregnancy by Einstein. She and Einstein married in 1903 and had two sons, but the marriage failed. So was Mileva her husband’s uncredited coauthor, unpaid assistant, or his essential helpmeet? It’s tempting to believe that she was her husband’s secret collaborator, but the authors of Einstein's Wife look at the actual evidence, and a chapter by Ruth Lewin Sime offers important historical context. The story they tell is that of a brave and determined young woman who struggled against a variety of obstacles at a time when science was not very welcoming to women. Given the barriers women in science still face, [Mileva’s] story remains relevant.” —Washington Post

The Vaccine Race

Author : Meredith Wadman
Publisher : Penguin
ISBN 13 : 0143111310
Total Pages : 466 pages
Book Rating : 4.1/5 (431 download)

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Book Synopsis The Vaccine Race by : Meredith Wadman

Download or read book The Vaccine Race written by Meredith Wadman and published by Penguin. This book was released on 2018-09-04 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times “Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—Nature The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus--measles--on the rise today, no medical story could have more human drama, impact, or urgency than The Vaccine Race.

To Build a Better World

Author : Philip Zelikow
Publisher : Twelve
ISBN 13 : 1538764660
Total Pages : 528 pages
Book Rating : 4.5/5 (387 download)

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Book Synopsis To Build a Better World by : Philip Zelikow

Download or read book To Build a Better World written by Philip Zelikow and published by Twelve. This book was released on 2019-09-10 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: A deeply researched international history and "exemplary study" (New York Times Book Review) of how a divided world ended and our present world was fashioned, as the world drifts toward another great time of choosing. Two of America's leading scholar-diplomats, Philip Zelikow and Condoleezza Rice, have combed sources in several languages, interviewed leading figures, and drawn on their own firsthand experience to bring to life the choices that molded the contemporary world. Zeroing in on the key moments of decision, the might-have-beens, and the human beings working through them, they explore both what happened and what could have happened, to show how one world ended and another took form. Beginning in the late 1970s and carrying into the present, they focus on the momentous period between 1988 and 1992, when an entire world system changed, states broke apart, and societies were transformed. Such periods have always been accompanied by terrible wars -- but not this time. This is also a story of individuals coping with uncertainty. They voice their hopes and fears. They try out desperate improvisations and careful designs. These were leaders who grew up in a "postwar" world, who tried to fashion something better, more peaceful, more prosperous, than the damaged, divided world in which they had come of age. New problems are putting their choices, and the world they made, back on the operating table. It is time to recall not only why they made their choices, but also just how great nations can step up to great challenges. Timed for the thirtieth anniversary of the fall of the Berlin Wall, To Build a Better World is an authoritative depiction of contemporary statecraft. It lets readers in on the strategies and negotiations, nerve-racking risks, last-minute decisions, and deep deliberations behind the dramas that changed the face of Europe -- and the world -- forever.

Readings in Molecular Biology

Author : W. B. Gratzer
Publisher : Mit Press
ISBN 13 : 9780262570251
Total Pages : 168 pages
Book Rating : 4.5/5 (72 download)

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Book Synopsis Readings in Molecular Biology by : W. B. Gratzer

Download or read book Readings in Molecular Biology written by W. B. Gratzer and published by Mit Press. This book was released on 1971 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of topical essays on noteworthy discoveries in the biological sciences published in the journal Nature.

The Origins of Life

Author : D. W. Deamer
Publisher : Cold Spring Harbor Perspective
ISBN 13 : 9781936113040
Total Pages : 0 pages
Book Rating : 4.1/5 (13 download)

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Book Synopsis The Origins of Life by : D. W. Deamer

Download or read book The Origins of Life written by D. W. Deamer and published by Cold Spring Harbor Perspective. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems. Also covered in the book are new synthetic approaches for fabricating cellular systems, the potentially extraterrestrial origin of life's building blocks, and the possibility that life once existed on Mars. Comprising five sections Setting the Stage, Components of First Life, Primitive Systems, First Polymers, and Transition to a Microbial World it is a vital reference for all scientists interested in the origin of life on Earth and the likelihood that it has arisen on other planets

Algorithms in Structural Molecular Biology

Author : Bruce R. Donald
Publisher : MIT Press
ISBN 13 : 0262548798
Total Pages : 497 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Algorithms in Structural Molecular Biology by : Bruce R. Donald

Download or read book Algorithms in Structural Molecular Biology written by Bruce R. Donald and published by MIT Press. This book was released on 2023-08-15 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of algorithms important to computational structural biology that addresses such topics as NMR and design and analysis of proteins.Using the tools of information technology to understand the molecular machinery of the cell offers both challenges and opportunities to computational scientists. Over the past decade, novel algorithms have been developed both for analyzing biological data and for synthetic biology problems such as protein engineering. This book explains the algorithmic foundations and computational approaches underlying areas of structural biology including NMR (nuclear magnetic resonance); X-ray crystallography; and the design and analysis of proteins, peptides, and small molecules. Each chapter offers a concise overview of important concepts, focusing on a key topic in the field. Four chapters offer a short course in algorithmic and computational issues related to NMR structural biology, giving the reader a useful toolkit with which to approach the fascinating yet thorny computational problems in this area. A recurrent theme is understanding the interplay between biophysical experiments and computational algorithms. The text emphasizes the mathematical foundations of structural biology while maintaining a balance between algorithms and a nuanced understanding of experimental data. Three emerging areas, particularly fertile ground for research students, are highlighted: NMR methodology, design of proteins and other molecules, and the modeling of protein flexibility. The next generation of computational structural biologists will need training in geometric algorithms, provably good approximation algorithms, scientific computation, and an array of techniques for handling noise and uncertainty in combinatorial geometry and computational biophysics. This book is an essential guide for young scientists on their way to research success in this exciting field.

Undo It!

Author : Dean Ornish, M.D.
Publisher : Ballantine Books
ISBN 13 : 0525480021
Total Pages : 530 pages
Book Rating : 4.5/5 (254 download)

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Book Synopsis Undo It! by : Dean Ornish, M.D.

Download or read book Undo It! written by Dean Ornish, M.D. and published by Ballantine Books. This book was released on 2022-01-04 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER • By the pioneer of lifestyle medicine, a simple, scientifically program proven to often reverse the progression of the most common and costly chronic diseases and even begin reversing aging at a cellular level! Long rated “#1 for Heart Health” by U.S. News & World Report, Dr. Ornish’s Program is now covered by Medicare when offered virtually at home. Dean Ornish, M.D., has directed revolutionary research proving, for the first time, that lifestyle changes can often reverse—undo!—the progression of many of the most common and costly chronic diseases and even begin reversing aging at a cellular level. Medicare and many insurance companies now cover Dr. Ornish’s lifestyle medicine program for reversing chronic disease because it consistently achieves bigger changes in lifestyle, better clinical outcomes, larger cost savings, and greater adherence than have ever been reported—based on forty years of research published in the leading peer-reviewed medical and scientific journals. Now, in this landmark book, he and Anne Ornish present a simple yet powerful new unifying theory explaining why these same lifestyle changes can reverse so many different chronic diseases and how quickly these benefits occur. They describe what it is, why it works, and how you can do it: • Eat well: a whole foods, plant-based diet naturally low in fat and sugar and high in flavor. The “Ornish diet” has been rated “#1 for Heart Health” by U.S. News & World Report for eleven years since 2011. • Move more: moderate exercise such as walking • Stress less: including meditation and gentle yoga practices • Love more: how love and intimacy transform loneliness into healing With seventy recipes, easy-to-follow meal plans, tips for stocking your kitchen and eating out, recommended exercises, stress-reduction advice, and inspiring patient stories of life-transforming benefits—for example, several people improved so much after only nine weeks they were able to avoid a heart transplant—Undo It! empowers readers with new hope and new choices. Praise for Undo It! “The Ornishes’ work is elegant and simple and deserving of a Nobel Prize, since it can change the world!”—Richard Carmona, M.D., MPH, FACS, seventeenth Surgeon General of the United States “If you want to see what medicine will be like ten years from now, read this book today.”—Rita F. Redberg, M.D., editor in chief, JAMA Internal Medicine “This is one of the most important books on health ever written.”—John Mackey, CEO, Whole Foods Market

Ending Aging

Author : Aubrey de Grey
Publisher : Macmillan + ORM
ISBN 13 : 1429931833
Total Pages : 452 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Ending Aging by : Aubrey de Grey

Download or read book Ending Aging written by Aubrey de Grey and published by Macmillan + ORM. This book was released on 2007-09-04 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Computational Molecular Biology

Author : S. Istrail
Publisher : Gulf Professional Publishing
ISBN 13 : 9780444513847
Total Pages : 196 pages
Book Rating : 4.5/5 (138 download)

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Book Synopsis Computational Molecular Biology by : S. Istrail

Download or read book Computational Molecular Biology written by S. Istrail and published by Gulf Professional Publishing. This book was released on 2003-04-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers demonstrating the variety and richness of computational problems motivated by molecular biology. The application areas within biology that give rise to the problems studied in these papers include solid molecular modeling, sequence comparison, phylogeny, evolution, mapping, DNA chips, protein folding and 2D gel technology. The mathematical techniques used are algorithmics, combinatorics, optimization, probability, graph theory, complexity and applied mathematics. This is the fourth volume in the Discrete Applied Mathematics series on computational molecular biology, which is devoted to combinatorial and algorithmic techniques in computational molecular biology. This series publishes novel research results on the mathematical and algorithmic foundations of the inherently discrete aspects of computational biology. Key features: . protein folding . phylogenetic inference . 2-dimensional gel analysis . graphical models for sequencing by hybridisation . dynamic visualization of molecular surfaces . problems and algorithms in sequence alignment This book is a reprint of Discrete Applied Mathematics Volume 127, Number 1.

Younger

Author : Sara Gottfried
Publisher : HarperCollins
ISBN 13 : 006231629X
Total Pages : 249 pages
Book Rating : 4.0/5 (623 download)

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Book Synopsis Younger by : Sara Gottfried

Download or read book Younger written by Sara Gottfried and published by HarperCollins. This book was released on 2017-03-07 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER The New York Times bestselling author of The Hormone Cure and The Hormone Reset Diet shows every woman how to create a lifestyle that will help her look great, feel energized, and slow down the effects of aging. Feel destined for cellulite, saddle bags, and belly fat? Does your family come from a long line of Alzheimer's, cancer, or heart disease? Will nothing help your aging skin or declining libido or flagging energy? This book is for you. The body is magnificent but it doesn't come with a lifetime warranty, or an operating manual. You're the result of millions of years of evolution, but many of the adaptations that helped your ancestors survive are now working overtime to accelerate the aging process. The assumption here is that we are our genes and therefore trapped by the past. The good news is that your genetic code—the DNA sequence that is the biochemical basis of heredity—can play a minor role in the way you age. The scientific reality is that 90 percent of the signs of aging and disease are caused by lifestyle choices, not your genes. In other words, you have the capability to overcome and transform your genetic history and tendencies. Harvard/MIT—trained physician Sara Gottfried, M.D. has created a revolutionary 7-week program that empowers us to make the critical choices necessary to not just look young, but also feel young. Dr. Gottfried identifies and builds this book around the five-key factors that lead to accelerated aging -the muscle factor, the brain factor, the hormone factor, the gut factor, and the toxic fat factor. The 7-week program addresses these factors and treats them in an accessible and highly practical protocol and is as follows: Feed—Week 1 Sleep—Week 2 Move—Week 3 Release—Week 4 Expose—Week 5 Soothe—Week 6 Think—Week 7 Younger increases not only your lifespan, but also your healthspan. Dr. Gottfried's program makes it possible to change the way you age, stay younger longer, and remain healthy and vibrant for all of your days.

Telomeres and Telomerase in Aging, Disease, and Cancer

Author : K. Lenhard Rudolph
Publisher : Springer Science & Business Media
ISBN 13 : 354073709X
Total Pages : 332 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Telomeres and Telomerase in Aging, Disease, and Cancer by : K. Lenhard Rudolph

Download or read book Telomeres and Telomerase in Aging, Disease, and Cancer written by K. Lenhard Rudolph and published by Springer Science & Business Media. This book was released on 2007-11-07 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that limit cellular lifespan and survival in response to telomere dysfunction. There is special focus on adult stem cells.