Electrophysiological Methods

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Basic Electrophysiological Methods

Author : Ellen Covey
Publisher : Oxford University Press
ISBN 13 : 0199342547
Total Pages : 256 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Basic Electrophysiological Methods by : Ellen Covey

Download or read book Basic Electrophysiological Methods written by Ellen Covey and published by Oxford University Press. This book was released on 2015-02-25 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.

Introduction to Electrophysiological Methods and Instrumentation

Author : Franklin Bretschneider
Publisher : Academic Press
ISBN 13 : 0128142111
Total Pages : 370 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Introduction to Electrophysiological Methods and Instrumentation by : Franklin Bretschneider

Download or read book Introduction to Electrophysiological Methods and Instrumentation written by Franklin Bretschneider and published by Academic Press. This book was released on 2018-11-13 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists, neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals. Introduces possibilities and solutions, along with the problems, pitfalls, and artefacts of equipment and electrodes Discusses the particulars of recording from brain tissue slices, oocytes and planar bilayers Describes optical methods pertinent to electrophysiological practice Presents the fundamentals of signal processing of analogue signals, spike trains and single channel recordings, along with procedures for signal recording and processing Includes appendices on electrical safety and foundations of useful mathematical tools

Electrophysiological Recording Techniques

Author : Robert P. Vertes
Publisher : Humana Press
ISBN 13 : 9781603272018
Total Pages : 0 pages
Book Rating : 4.2/5 (72 download)

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Book Synopsis Electrophysiological Recording Techniques by : Robert P. Vertes

Download or read book Electrophysiological Recording Techniques written by Robert P. Vertes and published by Humana Press. This book was released on 2010-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applying neurophysiological methods to the study of brain-behavior relationships proved to be a major advance in the early days of neuroscience research. Considerable technological progress has been made very recently, and the impact on modern neuroscience will be invaluable. In Electrophysiological Recording Techniques, experts in the field present a current view of the widespread application of electrophysiological methods to the study of the brain and to the problem of brain-behavior relationships. The book has been organized to display the range of modern neurophysiological methods ranging from the recordings of single neurons and neuronal ensembles to recordings of field potentials within discrete brain regions and across multiple brain areas. Many of the chapters also address the major challenge of applying the appropriate methods to analyze and interpret neurophysiological recording data. As a volume in the popular Neuromethods series, the chapters provide authoritative reviews of many commonly used approaches in the field today in both the basic research level and in clinical settings. Practical and up-to-date, Electrophysiological Recording Techniques serves as a key reference volume for researchers working in this ever-changing and vital field.

Electrophysiological Methods in Biological Research

Author : Jan Bures
Publisher : Academic Press
ISBN 13 : 148326145X
Total Pages : 825 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Electrophysiological Methods in Biological Research by : Jan Bures

Download or read book Electrophysiological Methods in Biological Research written by Jan Bures and published by Academic Press. This book was released on 2013-10-22 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrophysiological Methods in Biological Research, Third Revised Edition describes the principles and applications of significant electrophysiological methods as regards to transistorisation of electrophysiological apparatus and to the mathematical analysis of electrophysiological data. The book explains the aspects of physics and electronics that are important in electrophysiology, such as the basic principles of semiconductor function, electronic simulators, electrodes, and the processing of electrophysiological data. The text also cites several examples that measure the resulting membrane potential if one electrode is inside the cell while the other is in contact with the cell's surface. Other experiments show the electrophysiological techniques and the fundamentals of electrical activity in the peripheral excitable structures, and its association with physiological functions. In considering the problems of nerve and muscle physiology, the investigator should know the technique of recording the electrical signs of a nerve impulse. These signs, or action potentials, indicate the presence of a nerve impulse. The text also discusses the effects of barbiturates or ether anesthesia in EEG activity, as well as its dissociation after physostigmine and atropine have been administered. The book can prove useful for pharmacologists, microchemists, cellular biologists, and research workers and technologists dealing with neural mechanisms.

Cardiac Electrophysiology Methods and Models

Author : Daniel C. Sigg
Publisher : Springer Science & Business Media
ISBN 13 : 1441966587
Total Pages : 490 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Cardiac Electrophysiology Methods and Models by : Daniel C. Sigg

Download or read book Cardiac Electrophysiology Methods and Models written by Daniel C. Sigg and published by Springer Science & Business Media. This book was released on 2010-09-11 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

Basic Electrophysiological Methods

Author : Ellen Covey
Publisher : Oxford University Press, USA
ISBN 13 : 0199939802
Total Pages : 241 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Basic Electrophysiological Methods by : Ellen Covey

Download or read book Basic Electrophysiological Methods written by Ellen Covey and published by Oxford University Press, USA. This book was released on 2015 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: A broad, concise, and no-nonsense guide to contemporary electrophysiological techniques, covering intracellular and extracellular recording through recording of population activity, neuropharmacology, dye imaging, voltammetry, and optogenetics.

Guide to Research Techniques in Neuroscience

Author : Matt Carter
Publisher : Academic Press
ISBN 13 : 0323915612
Total Pages : 416 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Guide to Research Techniques in Neuroscience by : Matt Carter

Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step

Electrophysiological Methods

Author : William L. Nastuk
Publisher : Elsevier
ISBN 13 : 1483194914
Total Pages : 442 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Electrophysiological Methods by : William L. Nastuk

Download or read book Electrophysiological Methods written by William L. Nastuk and published by Elsevier. This book was released on 2013-10-22 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Techniques in Biological Research Volume VI: Electrophysiological Methods presents the analytical methods and experimental techniques in electrophysiological research. It discusses the handling and analysis of information by computer methods. It addresses the methods of analysis of waveforms, signal characterization and detection. Some of the topics covered in the book are the fundamentals of digital and analog computers; analysis of complex waveforms; operational amplifiers; signal processing and parameter estimation; the core conductor model; voltage clamp techniques; cable theory; automatic computation equipment; and electric accounting machinery. The wave shape generation are covered. The characterization of systematic functions is discussed. The text describes the nerve containing axial wire. A study of the internal thin and outer diffuse electrodes is presented. A chapter is devoted to the simple one dimensional model. Another section focuses on the cylindrical model with radial symmetry and accuracy of membrane potential measurement. The book can provide useful information to experimenters, students, and researchers.

Practical Electrophysiological Methods

Author : Helmut Kettenmann
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 480 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Practical Electrophysiological Methods by : Helmut Kettenmann

Download or read book Practical Electrophysiological Methods written by Helmut Kettenmann and published by Wiley-Liss. This book was released on 1992-11-11 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to enable newcomers to electrophysiology to choose appropriate preparations and techniques for in vitro studies in vertebrate neurobiology. Emphasizes techniques involving the glass micropipette and other recently developed methods, supplementing easy-to-follow instructions with illustrative schemes, examples of original records, photomicrographs, key word listings, comprehensive reference tables and a list of suppliers and key equipment and reagents.

Electrophysiology

Author : Jürgen Rettinger
Publisher : Springer Nature
ISBN 13 : 3030864820
Total Pages : 226 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Electrophysiology by : Jürgen Rettinger

Download or read book Electrophysiology written by Jürgen Rettinger and published by Springer Nature. This book was released on 2022-02-11 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and revised textbook presents a broad overview on topics concerning cellular electrophysiology – ranging from bioelectric phenomena recognized as far back as ancient Egypt to popular topics on the dangers of electrosmog. Without sacrificing scientific precision, this clear and concise work presents on the one hand the different methods and modern applications, on the other hand the biophysical fundamentals of ion-channel and carrier proteins. Numerous and carefully selected illustrations and diagrams supplement the text. Each chapter is extended by a detailed table of Take-Home Messages. Questions at the end of each chapter allow readers to test their understanding. Each section also includes references to relevant original literature for further reading. The book offers a valuable resource for students of biology, chemistry and physics with a special interest in biophysics.

Plant Electrophysiology

Author : Alexander G. Volkov
Publisher : Springer Science & Business Media
ISBN 13 : 354037843X
Total Pages : 513 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Plant Electrophysiology by : Alexander G. Volkov

Download or read book Plant Electrophysiology written by Alexander G. Volkov and published by Springer Science & Business Media. This book was released on 2007-04-19 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles new findings in plant electrophysiology from the work of internationally renowned experts in the fields of electrophysiology, bio-electrochemistry, biophysics, signal transduction, phloem transport, tropisms, ion channels, plant electrochemistry, and membrane transport. Opening with a historical introduction, the book reviews methods in plant electrophysiology, introducing such topics as measuring membrane potentials and ion fluxes, path-clamp technique, and electrochemical sensors. The coverage includes experimental results and their theoretical interpretation.

Electrophysiological Analysis of Synaptic Transmission

Author : Nicholas Graziane
Publisher : Humana
ISBN 13 : 9781071625910
Total Pages : 0 pages
Book Rating : 4.6/5 (259 download)

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Book Synopsis Electrophysiological Analysis of Synaptic Transmission by : Nicholas Graziane

Download or read book Electrophysiological Analysis of Synaptic Transmission written by Nicholas Graziane and published by Humana. This book was released on 2023-08-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches.

Patch Clamp Electrophysiology

Author : Mark Dallas
Publisher : Humana
ISBN 13 : 9781071608203
Total Pages : 333 pages
Book Rating : 4.6/5 (82 download)

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Book Synopsis Patch Clamp Electrophysiology by : Mark Dallas

Download or read book Patch Clamp Electrophysiology written by Mark Dallas and published by Humana. This book was released on 2021-11-13 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes a range of standard and novel methodological approaches used to probe ion channel function across different modalities. Chapters guide readers through methods and protocols from an introduction to the decades old patch clamp method for the ion channel neophyte to more complex, recent protocol advances, such as optogenetics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Patch Clamp Electrophysiology: Methods and Protocols aims to be a reference guide for current and future ion channel physiologists.

Electrophysiological Recording Techniques

Author : Robert P Vertes
Publisher : Springer Nature
ISBN 13 : 1071626310
Total Pages : 256 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Electrophysiological Recording Techniques by : Robert P Vertes

Download or read book Electrophysiological Recording Techniques written by Robert P Vertes and published by Springer Nature. This book was released on 2022-09-06 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition expands on the previous volume by incorporating state-of-the-art electrophysiological and anatomical methods and their application to the study of several systems of the brain involved in a range of functions. Chapters in this edition cover topics such as the value and difficulty of multi-site recordings using depth or surface electrodes; an assessment of different electrophysiological techniques used in non-human animals and humans; applying single-unit and ensemble recordings to the study of temporal dynamics in cognition; approaches to electroencephalography (EEG) recordings applied to mouse research; recordings of the nucleus reuniens of the ventral midline thalamus; and a comprehensive account of intracranial electroencephalography performed in patients with drug resistant epilepsy. In the Neuromethods series style, chapters include the type of detail and key advice from specialists needed to obtain successful results in your laboratory. Comprehensive and thorough, Electrophysiological Recording Techniques, Second Edition is a valuable resource for researchers and clinicians to help them utilize the principles and research designs described herein in their programs.

Patch Clamping

Author : Areles Molleman
Publisher : John Wiley & Sons
ISBN 13 : 0470856513
Total Pages : 186 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Patch Clamping by : Areles Molleman

Download or read book Patch Clamping written by Areles Molleman and published by John Wiley & Sons. This book was released on 2003-06-13 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells. Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results. This book will explain the basic principles and practical application of patch clamp electrophysiology Written in a non-technical style to ensure its broad appeal to novice users Takes a practical approach This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns

Electrophysiological Maneuvers for Arrhythmia Analysis

Author : George J. Klein MD
Publisher : Cardiotext Publishing
ISBN 13 : 1935395157
Total Pages : 211 pages
Book Rating : 4.9/5 (353 download)

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Book Synopsis Electrophysiological Maneuvers for Arrhythmia Analysis by : George J. Klein MD

Download or read book Electrophysiological Maneuvers for Arrhythmia Analysis written by George J. Klein MD and published by Cardiotext Publishing. This book was released on 2014-05-01 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: From senior electrophysiologist and world-class educator George Klein, a fully illustrated guide with over 100 intracardiac tracings and figures that allow the physician to approach electrophysiologic problems effectively and systematically. The book is especially focused on electrophysiological maneuvers and provides a clear and understandable guide to their proper selection and interpretation using abundant clinical examples. Defines the integral role for "traditional" electrogram (EGM) analysis in order to understand the mechanism of a tachycardia. It goes without saying that a correct arrhythmia diagnosis is a prerequisite to catheter ablation regardless of the presence of sophisticated mapping and imaging technologies. Electrophysiological maneuvers are fundamental to this process, and proper selection and interpretation of maneuvers constitute a core skill of the electrophysiologist. In this volume, we make the case that most maneuvers are fundamentally similar in principle and can be understood by appreciating a few basic physiological and anatomical principles. The art lies not in a comprehensive knowledge by rote of every maneuver or its application, but rather a systematic approach using common principles. We illustrate this by showing abundant examples and emphasizing the "game plan," including checklists that can be applied to virtually any maneuver. —George J. Klein In my opinion, this book should be on the shelf of every electrophysiologist trainee as well as every clinical cardiac electrophysiologist. It is a classic, like its editor. Dr. Klein deserves high praise for organizing his and his colleagues’ clinical experiences and thought processes into a concise, practical text that should be part of all training programs in electrophysiology. —From the foreword by Mark E. Josephson, MD

Computer Analysis of Electrophysiological Signals

Author : John Dempster
Publisher :
ISBN 13 : 9780122089404
Total Pages : 228 pages
Book Rating : 4.0/5 (894 download)

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Book Synopsis Computer Analysis of Electrophysiological Signals by : John Dempster

Download or read book Computer Analysis of Electrophysiological Signals written by John Dempster and published by . This book was released on 1993-01-01 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Volume in the Biological Techniques Series. This essential bench-top manual is the first comprehensive introduction to the principles and practice of the analysis of electrophysiological signals. The text describes hardware and software, including specific techniques for the analysis of single ion channels, noise analysis, and voltage-clamped whole cell currents. Rather than simply providing a manual describing how to use computer programs, this book provides insight into why programs operate in particular ways, the pitfalls awaiting the unwary, and the general philosophy behind signal analysis techniques. Examples of program source code are included. Key Features * Explains the principles of the digitization of analog signals * Provides practical examples for hardware in common use in the electrophysiological laboratory