Electrophysiological Analysis Of Synaptic Transmission

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Electrophysiological Analysis of Synaptic Transmission

Author : Nicholas Graziane
Publisher : Springer Nature
ISBN 13 : 1071625896
Total Pages : 283 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Electrophysiological Analysis of Synaptic Transmission by : Nicholas Graziane

Download or read book Electrophysiological Analysis of Synaptic Transmission written by Nicholas Graziane and published by Springer Nature. This book was released on 2022-08-03 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches.

Electrophysiological Analysis of Synaptic Transmission

Author : John I. Hubbard
Publisher : Hodder Education
ISBN 13 :
Total Pages : 444 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Electrophysiological Analysis of Synaptic Transmission by : John I. Hubbard

Download or read book Electrophysiological Analysis of Synaptic Transmission written by John I. Hubbard and published by Hodder Education. This book was released on 1969 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sensory Hair Cells

Author : Georgij N. Akoev
Publisher : Springer
ISBN 13 : 9783642779213
Total Pages : 0 pages
Book Rating : 4.7/5 (792 download)

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Book Synopsis Sensory Hair Cells by : Georgij N. Akoev

Download or read book Sensory Hair Cells written by Georgij N. Akoev and published by Springer. This book was released on 2011-11-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph summarizes the results of the authors' own in- vestigations as well as relevant literature data about the mechanism of synaptic transmission in sensory hair cells of the acousticolater- al system. It deals mainly with primary processes in hair cells. Ad- ditionally, data on the properties and selectivity of various ionic channels are presented, with data concerning the mechanism of release of the neurotransmitter from the hair cell and the proper- ties of postsynaptic responses of afferent fibres. The role of ex- citatory amino acids in synaptic transmission is analyzed. This book gives a comprehensive overview of current research on synaptic transmission in sensory hair cells, which should be valuable to both those in the field and neuroscientists of various disciplines. St. Petersburg, January 1993 G.N. Akoev G. N. Andrianov Table of Contents Introduction ...................................... . Chapter 1 Anatomy of the Mecha- and Electroreceptors of the Acousticolateral System 3 1.1 The Organ of Corti ............................ 3 1.2 Semicircular Canals ............................ 8 1.3 The Otolith Organs ............................ 11 1.4 Lateral-Line Organs ............................ 15 1.5 Electroreceptors ............................... 20 1.5.1 Ampullary Receptors ........................... 21 1.5.2 Tuberous Receptors ............................ 26 Chapter 2 Electrophysiological Analysis of Synaptic lhlnsmission in Hair Cells ................ 33 2.1 Electrical Characteristics of Hair Cells.

Synaptic Modifications and Memory

Author : L. L. Voronin
Publisher : Springer
ISBN 13 :
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Synaptic Modifications and Memory by : L. L. Voronin

Download or read book Synaptic Modifications and Memory written by L. L. Voronin and published by Springer. This book was released on 1993-05-27 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding of memory and learning is one of the major goals of neuroscientists and psychologists. The author first introduces the reader into the current state of knowledge of the mechanisms underlying memory by providing extensive reviews of contemporary results including behavioural approaches and molecular studies. He presents results of his group obtained by analysing elec- trical activity - including single neuron meassures. As a major experimental model the phenomenon of hippocampal long- term potentiation was studied. The so-called quantal analy- sis - a quantitative method - was applied to study mammalian brain plasticity. Short- and long-term synaptic plasticities were registered both in vivo and in vitro mammalian brain preparations. Results show the involvement of mainly presynaptic location in memory, however, the possible involvement of postsynaptic mechanisms is indicated by changes in quantal amplitude as shown by the author.

Electrophysiology

Author : D. I. Wallis
Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Electrophysiology by : D. I. Wallis

Download or read book Electrophysiology written by D. I. Wallis and published by . This book was released on 1993 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrophysiological techniques are vital to modern biology in general and are of particular significance in neuroscience. This volume provides a practical introduction to the methods used for studying single cells and complex neural tissues. Detailed advice is given not only for handling and culturing neural tissues and cells, but also for the mathematical approaches to modeling neuronal behavior and analysing the quantal release of neurotransmitters. An important sourcebook of protocols, helpful hints, and expert advice, it will prove invaluable to researchers in neuroscience, physiology, cell biology, and related areas

The Synapse

Author : Virginia M. Pickel
Publisher : Elsevier
ISBN 13 : 0124186823
Total Pages : 512 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis The Synapse by : Virginia M. Pickel

Download or read book The Synapse written by Virginia M. Pickel and published by Elsevier. This book was released on 2013-11-16 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. A comprehensive reference focused on the structure and function of the synapse Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment

Jasper's Basic Mechanisms of the Epilepsies

Author : Jeffrey L. Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey L. Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey L. Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus

Author : Wickliffe Abraham
Publisher :
ISBN 13 : 9780530018683
Total Pages : 158 pages
Book Rating : 4.0/5 (186 download)

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Book Synopsis An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus by : Wickliffe Abraham

Download or read book An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus written by Wickliffe Abraham and published by . This book was released on 2019-12-08 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: This is a PhD thesis that investigated how chronic ethanol consumption by rats, followed by 2 months of abstinence, affected the functional connectivity of several pathways in the hippocampus. The techniques entailed field potential electrophysiology in anesthetized animals, which was used to investigate basal synaptic transmission, short-term plasticity and long-term potentiaton. Connectivity patterns were assessed using current source density analyses of depth profile data. The findings have been published as 4 papers in 1981, 1982, 1984. Dissertation Discovery Company and the University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus" by Wickliffe Carson Abraham, was obtained from the University of Florida and is being sold with permission from the author. A free digital copy of this work may also be found in the university's institutional repository, the IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.

Basic Electrophysiological Methods

Author : Ellen Covey
Publisher : Oxford University Press
ISBN 13 : 0199342547
Total Pages : 256 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Basic Electrophysiological Methods by : Ellen Covey

Download or read book Basic Electrophysiological Methods written by Ellen Covey and published by Oxford University Press. This book was released on 2015-02-25 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.

Nerve and Muscle

Author : R. D. Keynes
Publisher : Cambridge University Press
ISBN 13 : 9780521805841
Total Pages : 196 pages
Book Rating : 4.8/5 (58 download)

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Book Synopsis Nerve and Muscle by : R. D. Keynes

Download or read book Nerve and Muscle written by R. D. Keynes and published by Cambridge University Press. This book was released on 2001-03-15 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential textbook for all undergraduate students of neurobiology, physiology, cell biology and preclinical medicine.

Principles and Practice of Clinical Electrophysiology of Vision, second edition

Author : John R. Heckenlively
Publisher : MIT Press
ISBN 13 : 0262083469
Total Pages : 1033 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Principles and Practice of Clinical Electrophysiology of Vision, second edition by : John R. Heckenlively

Download or read book Principles and Practice of Clinical Electrophysiology of Vision, second edition written by John R. Heckenlively and published by MIT Press. This book was released on 2006-04-07 with total page 1033 pages. Available in PDF, EPUB and Kindle. Book excerpt: The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.

Basic Neurochemistry

Author : Scott Brady
Publisher : Academic Press
ISBN 13 : 0080959016
Total Pages : 1120 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Basic Neurochemistry by : Scott Brady

Download or read book Basic Neurochemistry written by Scott Brady and published by Academic Press. This book was released on 2011-11-02 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475

The Squid Giant Synapse

Author : Rodolfo Riascos Llinás
Publisher : Oxford University Press, USA
ISBN 13 : 9780195116526
Total Pages : 234 pages
Book Rating : 4.1/5 (165 download)

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Book Synopsis The Squid Giant Synapse by : Rodolfo Riascos Llinás

Download or read book The Squid Giant Synapse written by Rodolfo Riascos Llinás and published by Oxford University Press, USA. This book was released on 1999 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for graduate and undergraduate courses, the book includes PC and Macintosh versions of two programs for simulating and manipulating any aspect of synaptic transmission."--BOOK JACKET.

Pharmacology of Neurotransmitter Release

Author : Thomas C. Südhof
Publisher : Springer Science & Business Media
ISBN 13 : 3540748059
Total Pages : 582 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Pharmacology of Neurotransmitter Release by : Thomas C. Südhof

Download or read book Pharmacology of Neurotransmitter Release written by Thomas C. Südhof and published by Springer Science & Business Media. This book was released on 2007-12-07 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.

History of the Synapse

Author : Max R. Bennett
Publisher : CRC Press
ISBN 13 : 0203302540
Total Pages : 351 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis History of the Synapse by : Max R. Bennett

Download or read book History of the Synapse written by Max R. Bennett and published by CRC Press. This book was released on 2003-09-02 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.

Neurobiology of Motor Control

Author : Scott L. Hooper
Publisher : John Wiley & Sons
ISBN 13 : 1118873343
Total Pages : 512 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Neurobiology of Motor Control by : Scott L. Hooper

Download or read book Neurobiology of Motor Control written by Scott L. Hooper and published by John Wiley & Sons. This book was released on 2017-06-12 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and movement currently available, Neurobiology of Motor Control is a must-read for all who study movement production and the neurobiological basis of movement—from molecular biologists to roboticists.

Guide to Research Techniques in Neuroscience

Author : Matt Carter
Publisher : Academic Press
ISBN 13 : 0323915612
Total Pages : 416 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Guide to Research Techniques in Neuroscience by : Matt Carter

Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step