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Ehlers Danlos Syndrome From Bedside To Bench
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Book Synopsis Ehlers-Danlos syndrome: From bedside to bench by : Tomoki Kosho
Download or read book Ehlers-Danlos syndrome: From bedside to bench written by Tomoki Kosho and published by Frontiers Media SA. This book was released on 2024-04-30 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Genes and Cardiovascular Function by : Bohuslav Ostadal
Download or read book Genes and Cardiovascular Function written by Bohuslav Ostadal and published by Springer Science & Business Media. This book was released on 2011-08-09 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology. In the embrace of modern molecular biology and bridging the gap between the clinical and the genomic, cardiovascular medicine has seen major strides in the understanding of the molecular mechanisms that drive disease progression. The ability to rapidly identify candidate human genes for cardiovascular diseases lends itself to the development of diverse strategies for disease treatment and management. The wide variety of gene expressions proffers excellent targets for novel therapeutics. Gene therapy is steadily increasing in viability and represents a fascinating arena of research and clinical focus. This book is based on two international Mendel symposia on “Genes and the Heart,” joint meetings of the Japanese and European sections of the International Academy of Cardiovascular Sciences. Highlighting selected symposia contributions, this book explores the role of molecular biology and genetics in the basic knowledge, genesis, and clinical interventions of cardiovascular diseases.
Book Synopsis Hurwitz Clinical Pediatric Dermatology E-Book by : Amy S. Paller
Download or read book Hurwitz Clinical Pediatric Dermatology E-Book written by Amy S. Paller and published by Elsevier Health Sciences. This book was released on 2015-09-25 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: This must-have clinical reference, by Drs. Amy S. Paller and Anthony J. Mancini, provides practical, authoritative guidance for identification and management of all types of skin disorders seen in children and adolescents. Hurwitz Clinical Pediatric Dermatology, 5th Edition, is ideal for pediatricians, dermatologists, family practitioners and anyone who sees children with skin disorders – no matter what level of experience you may have. Benefit from the knowledge and expertise of two leaders in the field, who provide a clearly written, consistent approach throughout the text. Stay on the cutting edge of what’s new in pediatric dermatology – from the neonate to the adolescent - with the latest drug developments and disease classifications. Recognize virtually any skin condition you’re likely to see thanks to more than 1,000 high-quality color images, including over 300 brand new to this edition. Find the most appropriate therapy options with updated evidence based guidance. Easily locate the information you need with more quick-reference boxes and summary tables throughout the text.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Control of Breathing during Sleep by : Susmita Chowdhuri
Download or read book Control of Breathing during Sleep written by Susmita Chowdhuri and published by CRC Press. This book was released on 2022-08-16 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes control of ventilation during sleep in both health and disease states. The topics are presented in a fashion that can be easily comprehended with many figures to illustrate complex concepts. Thus, a wide range of topics, starting from the site of normal respiratory rhythm generation to chemoreceptor control of sleep apnea, description of the apneic threshold, pathophysiology of upper airway closure, novel techniques to measure control of breathing, effect of cerebral blood flow on breathing, effect of opioids on ventilation, effect of heart failure on ventilation, genetic aspects of breathing disorders, age and gender differences, and various therapies are discussed. Key Features • Helps to bridge the gap between straight forward physiology and clinical practice through a range of topics and use of case vignettes • Explores various aspects of clinical management and control which is beneficial to sleep clinicians, respiratory physiologists, intensivists, trainees, and researchers. • Distills complex concepts into understandable language and figures, providing helping resource to the clinicians, that transforms a dry topic vis a viz control of ventilation into an exciting understandable ‘clinician’ language.
Book Synopsis Heart Failure in the Child and Young Adult by : Joseph Rossano
Download or read book Heart Failure in the Child and Young Adult written by Joseph Rossano and published by Academic Press. This book was released on 2017-12-05 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. - Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation - Combines cutting-edge research with current guidelines from the field
Download or read book Acute Stroke written by Anish Bhardwaj and published by CRC Press. This book was released on 2006-09-18 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the third leading cause of death in the United States, stroke accounts for one in every fifteen deaths and is the major cause of disability in the country. Compiled by a renowned editorial team, this reference bridges the gap between basic science and patient care protocols, and collects 43 expertly written chapters that range from laboratory-ba
Book Synopsis Colonic Motility by : Sushil K. Sarna
Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Book Synopsis Genomic and Precision Medicine by : Geoffrey S. Ginsburg
Download or read book Genomic and Precision Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2017-03-30 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care. One of the major areas where genomic and personalized medicine is most active is the realm of the primary care practitioner. Risk, family history, personal genomics and pharmacogenomics are becoming increasingly important to the PCP and their patients, and this book discusses the implications as they relate to primary care practitioners. - Presents a comprehensive volume for primary care providers - Provides succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine - Includes a current overview on major opportunities for genomic and personalized medicine in practice - Highlights case studies that illustrate the practical use of genomics in the management in patients
Book Synopsis Urogynecology & Pelvic Reconstructive Surgery by : Manidip Pal
Download or read book Urogynecology & Pelvic Reconstructive Surgery written by Manidip Pal and published by JP Medical Ltd. This book was released on 2016-04-30 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Urogynecology & Pelvic Reconstructive Surgery is a highly illustrated guide to the management and surgical treatment of a wide range of pelvic and urogynaecological problems. The book is comprised of 64 chapters across twelve comprehensive sections, beginning with a section on the basics of urogynaecological surgery. This section includes anatomy of the pelvic floor, urinary bladder, urethra and pelvic ureter, as well as associated nomenclature. The second and third sections cover diagnosis and treatment, and subsequent sections cover procedures for specific disorders, including rectal prolapse, urinary incontinence, pelvic organ prolapse, and vault prolapse. Further sections include uterus preserving surgeries, fistula, surgery for congenital anomalies, pregnancy, and miscellaneous surgical procedures. Enhanced by nearly 600 full colour images and illustrations, Urogynecology & Pelvic Reconstructive Surgery is an ideal resource for urogynaecologists, pelvic surgeons and residents. Key Points Highly illustrated guide to urogynaecology and pelvic reconstructive surgery Includes sections on anatomy, diagnosis and treatment, as well as specific surgical procedures 598 full colour images and illustrations
Book Synopsis Pediatric Dermatology, An Issue of Dermatologic Clinics, E-Book by : Kelly M. Cordoro
Download or read book Pediatric Dermatology, An Issue of Dermatologic Clinics, E-Book written by Kelly M. Cordoro and published by Elsevier Health Sciences. This book was released on 2021-11-22 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Dermatologic Clinics, Guest Editor Kelly M. Cordoro brings considerable expertise to the topic of Pediatric Dermatology. Top experts in the field cover key topics such as Epidermal Nevi in Children, Pigmented Lesions in Children, Normal Skin Findings in Pediatric Patients with Skin of Color, and more. - Provides in-depth, clinical reviews on pediatric dermatology, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 11 relevant, practice-oriented topics including Presentation of common skin disorders in pediatric patients with skin of color; Tips, Tricks and Pearls to Expertly Treating Common Skin Conditions in Pediatric Patients; Climate and Environmental Health as it Relates to Pediatric Dermatology; and more.
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Contemporary Challenges in Sudden Cardiac Death, An Issue of Cardiac Electrophysiology Clinics, E-Book by : Mohammad Shenasa
Download or read book Contemporary Challenges in Sudden Cardiac Death, An Issue of Cardiac Electrophysiology Clinics, E-Book written by Mohammad Shenasa and published by Elsevier Health Sciences. This book was released on 2017-11-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Cardiac Electrophysiology Clinics, edited by Drs. Mohammad Shenasa, N. A. Mark Estes III, and Gordon F. Tomaselli, will cover Contemporary Challenges in Sudden Cardiac Death. Topics covered in this issue include Pathophysiology; Basic electrophysiological mechanism; Channelopathy and Myopathy as causes of sudden cardiac death; Public access to defibrillation; Sudden cardiac death in children adolescence; Sudden cardiac death in specific cardiomyopathies; Ventricular arrhythmias and sudden cardiac death; lessons learned from cardiac implantable rhythm devices; future directions, and more.
Book Synopsis Paller and Mancini - Hurwitz Clinical Pediatric Dermatology E-Book by : Amy S Paller
Download or read book Paller and Mancini - Hurwitz Clinical Pediatric Dermatology E-Book written by Amy S Paller and published by Elsevier Health Sciences. This book was released on 2020-12-08 with total page 899 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by two leaders in the field of pediatric dermatology, this classic text provides both detailed content for the specialist and easily accessible information for the non-dermatologist and less experienced clinician. Paller and Mancini – Hurwitz Clinical Pediatric Dermatology, 6th Edition, comprehensively covers the full range of skin disorders in children, offering authoritative, practical guidance on diagnosis and treatment in a single volume. This award-winning, evidence-based text has been fully revised and updated, and is an essential resource for anyone who sees children with skin disorders. - Features new content outline boxes for faster navigation, hundreds more clinical images, and authors' tips for the diagnosis and treatment of pediatric skin diseases. - Contains updated, evidence-based guidance and the latest drug developments and disease classifications. - Provides a careful balance of narrative text, useful tables, and 1,300 high-quality clinical photographs, helping you recognize virtually any skin condition you're likely to see. - Includes a greatly expanded discussion of atopic dermatitis and psoriasis and new therapeutic approaches for treating genetic disorders and systemic diseases such as ichthyoses and rheumatologic disorders. - Discusses new tests for subclassifying disease, such as the myositis-specific antibodies of juvenile dermatomyositis, genotyping, and immunophenotypes of inflammatory skin disorders. - Contains new and updated tables on psoriasis co-morbidities, genetic syndrome classifications, acne therapies, pediatric histiocytoses, PHACE syndrome criteria, HSV therapies and juvenile dermatomyositis. - Features updated sections on infections, exanthems, vascular disorders, dermatoses and genodermatoses. - Discusses hot topics such as the use of stem cell and cell therapy, as well as recombinant protein, for treating epidermolysis bullosa; the resurgence of measles; congenital Zika virus infections; and much more.
Book Synopsis Biochemistry of Collagens, Laminins and Elastin by : Morten Karsdal
Download or read book Biochemistry of Collagens, Laminins and Elastin written by Morten Karsdal and published by Academic Press. This book was released on 2019-05-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease. - Provides an updated comprehensive introduction to collagen and structural proteins - Gives insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation - Includes seven new chapters, including one on how collagen biomarkers are used in clinical research to support drug development and in precision medicine - Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states - Proves the importance of proteins for collagen assembly, function, and durability
Book Synopsis Mastering Endovascular Techniques by : Peter Lanzer
Download or read book Mastering Endovascular Techniques written by Peter Lanzer and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an international group of master interventionists, this volume is a comprehensive, step-by-step guide to coronary and non-coronary endovascular techniques. After a review of vascular pathoanatomy, vascular pathophysiology, and peri-interventional diagnostics, the book details the principles and techniques of endovascular interventions in all vascular territories. Chapters cover intracranial vessels, internal carotid artery, coronary arteries, thoracic aorta, abdominal aortic aneurysm, renal arteries, iliac and lower extremity arteries, hemodialysis shunts, venous diseases, and foreign bodies. The authors offer guidelines on the choice of instrumentation and the decision-making process at each step of the intervention. More than 1,000 illustrations demonstrate the techniques.
Book Synopsis Comprehensive Insights into Mitral Valve Prolapse: From biology to future perspectives of treatment, passing through diagnostic tools, surgical techniques and transcatheter options by : Christophe Tribouilloy
Download or read book Comprehensive Insights into Mitral Valve Prolapse: From biology to future perspectives of treatment, passing through diagnostic tools, surgical techniques and transcatheter options written by Christophe Tribouilloy and published by Frontiers Media SA. This book was released on 2023-09-11 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitral valve prolapse (MVP), consisting of an abnormal protrusion of mitral leaflets into the left atrium, is the main cause of severe mitral regurgitation and it often requires surgical or interventional correction. It mainly represents a typical adult disease with an average prevalence in industrialized countries ranging from 2 to 8%, but even the pediatric population may be affected showing specific features concerning both anatomy and treatment. Although its existence and clinical characteristics are known for several decades, every aspect of this pathological condition is in continuous evolution, being the subject of biologists’, cardiologists’ and surgeons’ active research. The aim of the present Research Topic is to address the MVP entity in its completeness, trying to describe all actual knowledge concerning molecular mechanisms, different clinical presentations (fibroelastic degeneration in elderly people or Barlow disease in young patients), diagnostic findings and tools (mainly represented by echocardiography and Nuclear Magnetic Resonance), their specific application to newly developed transcatheter and minimally invasive treatments, indications, surgical management and interventional strategies. For all these big chapters, special attention will be addressed to show temporal knowledge evolution and new elements acquisition, since the central message is that MVP is in flux and far from full comprehension.