Mosaic of Autoimmunity

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Publisher : Academic Press
ISBN 13 : 012814307X
Total Pages : 728 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mosaic of Autoimmunity by : Carlo Perricone

Download or read book Mosaic of Autoimmunity written by Carlo Perricone and published by Academic Press. This book was released on 2019-02-13 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

Drug Discovery and Evaluation: Pharmacological Assays

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Publisher : Springer
ISBN 13 : 9783319053912
Total Pages : 0 pages
Book Rating : 4.0/5 (539 download)

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Book Synopsis Drug Discovery and Evaluation: Pharmacological Assays by : Franz J. Hock

Download or read book Drug Discovery and Evaluation: Pharmacological Assays written by Franz J. Hock and published by Springer. This book was released on 2015-11-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.

Drug Discovery and Evaluation

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Publisher : Springer Science & Business Media
ISBN 13 : 366203333X
Total Pages : 790 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Drug Discovery and Evaluation by : Hans G. Vogel

Download or read book Drug Discovery and Evaluation written by Hans G. Vogel and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.

Williams Hematology, 10th Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 126046413X
Total Pages : 2705 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis Williams Hematology, 10th Edition by : Kenneth Kaushansky

Download or read book Williams Hematology, 10th Edition written by Kenneth Kaushansky and published by McGraw Hill Professional. This book was released on 2021-01-14 with total page 2705 pages. Available in PDF, EPUB and Kindle. Book excerpt: The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of basic science and translational pathophysiology for optimal, lifelong learning. Experts in research and clinical hematology, the editors are known worldwide for their contributions to the field. This new edition contains everything that has made Williams Hematology the go-to resource for decades and has been updated with new chapters and critical new research into the molecular mechanisms responsible for hematological disorders and the impact on diagnosis and treatment. And the new format enables you to access each chapter via content modules covering key topics, with summaries, infographics, and cases―all linked to review questions for self-assessment. The full-color presentation integrates images of blood and tissue findings where they are cited in the text. NEW TO THIS EDITION: Updated and revised content reflecting the latest research and developments Convenient format that streamlines the learning process and improves retention Additional chapters added on: Immune Checkpoint Inhibitors Immune Cell Therapy: Chimeric Antigen Receptor T Cell Therapy Immune Cell Therapy Dendritic Cell and Natural Killer Cell Therapy The processes of cell death and survival Application of Big Data and Deep Learning in Hematology Williams Hematology Cases with multiple-choice questions including detailed explanations—perfect preparation for the boards Continuously updated online content with comprehensive drug therapy database and other resources

SITC’s Guide to Managing Immunotherapy Toxicity

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Publisher : Springer Publishing Company
ISBN 13 : 0826172156
Total Pages : 275 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis SITC’s Guide to Managing Immunotherapy Toxicity by : Marc S. Ernstoff, MD

Download or read book SITC’s Guide to Managing Immunotherapy Toxicity written by Marc S. Ernstoff, MD and published by Springer Publishing Company. This book was released on 2019-03-15 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Society for Immunotherapy of Cancer's handbook,SITC’s Guide to Managing Immunotherapy Toxicity, is a practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Separated into two parts, Part I contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with anti-CTLA4 agents, anti-PD1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is structured by common and uncommon toxicities that affect major organ sites throughout the body. It begins with a general summary of principles and management options followed by chapters focusing on specific toxicities such as rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, and ocular toxicities. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects with detailed summary tables for quick reference. Part II concludes with chapters covering management of special patient populations, including patients with autoimmune disease and geriatric patients, treatment and management of fatigue, and a final chapter dedicated to cost effectiveness and the toll of financial toxicity on patients and caregivers. With chapters written by world-recognized leaders in the immuno-oncology field, this text provides thorough coverage of the toxicity and management of adverse effects for immune checkpoint inhibitors. It is an indispensable resource for clinical oncologists, emergency physicians, hospitalists and other medical practitioners in both the hospital and community clinic settings, especially as the use of immune checkpoint inhibitors becomes a fixture in oncology care. Key Features: Outlines strategies for treating high-risk patients facing an acute or chronic side effect to immunotherapy Provides numerous tables that condense and highlight pertinent information for quick reference Describes the various clinical presentations and toxic reactions caused by immunotherapy Purchase includes access to the eBook for use on most mobile devices or computer

Molecular Diagnostics: Promises and Possibilities

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Publisher : Springer Science & Business Media
ISBN 13 : 9048132614
Total Pages : 527 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Molecular Diagnostics: Promises and Possibilities by : Mousumi Debnath

Download or read book Molecular Diagnostics: Promises and Possibilities written by Mousumi Debnath and published by Springer Science & Business Media. This book was released on 2010-01-29 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.

Leading Pharmaceutical Innovation

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Publisher : Springer
ISBN 13 : 3319668331
Total Pages : 189 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Leading Pharmaceutical Innovation by : Oliver Gassmann

Download or read book Leading Pharmaceutical Innovation written by Oliver Gassmann and published by Springer. This book was released on 2018-05-10 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical giants have been doubling their investments in drug development, only to see new drug approvals to remain constant for the past decade. This book investigates and highlights a set of proactive strategies, aimed at generating sustainable competitive advantage for its protagonists based on value-generating business practices. We focus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers for cutting-edge R&D, and new forms of internationalisation, such as outside-in innovation in the early phases of R&D.

The Manual of Dermatology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461409381
Total Pages : 585 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis The Manual of Dermatology by : Jennifer Cafardi

Download or read book The Manual of Dermatology written by Jennifer Cafardi and published by Springer Science & Business Media. This book was released on 2012-02-14 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Manual of Dermatology was developed by Dr. Cafardi at the University of Alabama at Birmingham, Department of Dermatology, and covers broad dermatological topics necessary for any dermatology resident treating patients. Topics include alopecia, medication dosing and management pearls, fungal disorders, genodermatoses, differential diagnoses of various skin diseases, management of infections, surgical anatomy and tips, HIV dermatology, pediatric dermatology, and skin cancer management and terminology. The practicality of this book is unique and includes key clinical data for residents, making it essential as a reference for quick differential diagnoses, work-up tips, management, and treatment options. This quick reference offers a more practical approach to dermatology, with drug names and dosing, and more information on mycology/onychomycosis than any other handbook on the market. The Manual of Dermatology is portable, comprehensive, easily accessible, and is based upon algorithms, tables, and pearls taught to dermatology medical students, making it a vital resource in all university medical libraries across the country.

Atlas of Dermatology in Internal Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1461406889
Total Pages : 160 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Atlas of Dermatology in Internal Medicine by : Néstor P. Sánchez

Download or read book Atlas of Dermatology in Internal Medicine written by Néstor P. Sánchez and published by Springer Science & Business Media. This book was released on 2011-12-02 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of Dermatology in Internal Medicine is the only concise text-atlas to cover the most common and most important cutaneous manifestations of systemic disease in children and adults. It features more than 150 clinical photographs that are accompanied by format-driven, clinically focused text on the diagnosis and management of cutaneous manifestations of connective tissue, pulmonary, renal, GI, endocrine, malignant, infectious, and HIV disease. There is also a separate chapter on skin diseases commonly seen in the ICU. A special feature is its systematic coverage of clinically relevant dermatopathology. The book is a helpful tool for physicians and trainees in internal medicine, family medicine, pediatrics, emergency medicine, and critical care medicine, as well as family, emergency, and critical care nurse practitioners.

Practical Guide to Dermatology

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Author :
Publisher : Springer Nature
ISBN 13 : 3030180158
Total Pages : 311 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Practical Guide to Dermatology by : Henry W. Lim

Download or read book Practical Guide to Dermatology written by Henry W. Lim and published by Springer Nature. This book was released on 2019-10-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical manual provides a real-world educationally focused resource. It enables the reader to gain a good understanding of a range of skin diseases, their differential diagnosis and various medical and/or surgical treatment options. Topics covered include general dermatology, oncodermatology, drugs, phototherapy, pigmentary disorders, skin of color, inpatient dermatology and pediatric dermatology. Emphasis is placed on concise, practical points that one can use in clinic, with informative pearls to reinforce the key messages in each chapter. Practical Guide to Dermatology: The Henry Ford Manual systematically describes a broad range of practical concepts, diagnostic and treatment techniques involving various dermatological disciplines. It represents a valuable reference guide for practising and trainee dermatologists alike.

Moderate to Severe Psoriasis

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Publisher : CRC Press
ISBN 13 : 0429585985
Total Pages : 422 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Moderate to Severe Psoriasis by : John Koo

Download or read book Moderate to Severe Psoriasis written by John Koo and published by CRC Press. This book was released on 2014-03-18 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis

Lippincott's Review for Medical-surgical Nursing Certification

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9781451116571
Total Pages : 442 pages
Book Rating : 4.1/5 (165 download)

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Book Synopsis Lippincott's Review for Medical-surgical Nursing Certification by : Lippincott

Download or read book Lippincott's Review for Medical-surgical Nursing Certification written by Lippincott and published by Lippincott Williams & Wilkins. This book was released on 2011-10-20 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lippincott's Review for Medical-Surgical Nursing Certification, Fifth Editionprovides the information nurses need to achieve certification in the specialty of medical-surgical nursing. This helpful reference covers the broad range of content found on the actual examinations, including disorders by body system, such as coronary artery disease, COPD, and diabetes. The product reviews signs and symptoms, diagnostic tests, medical treatments, nursing assessments, and interventions for scores of health problems. Concise refreshers on wound care, perioperative nursing, collaborative practice, nursing research, and legal issues are also included. Review questions after each chapter and an end-of-book posttest help assess the nurse's preparedness for the exam. The book is appropriate for exams of both major certifying bodies: the ANCC and the AMSN.

OZONE

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Publisher : Springer Science & Business Media
ISBN 13 : 904819234X
Total Pages : 330 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis OZONE by : Velio Bocci

Download or read book OZONE written by Velio Bocci and published by Springer Science & Business Media. This book was released on 2010-10-05 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygen-Ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classical biochemistry, physiological and pharmacological knowledge. Ozone is an oxidizing molecule, a sort of super active oxygen, which, by reacting with blood components generates a number of chemical messengers responsible for activating crucial biological functions such as oxygen delivery, immune activation, release of hormones and induction of antioxidant enzymes, which is an exceptional property for correcting the chronic oxidative stress present in atherosclerosis, diabetes and cancer. Moreover, by inducing nitric oxide synthase, ozone therapy may mobilize endogenous stem cells, which will promote regeneration of ischemic tissues. The description of these phenomena offers the first comprehensive picture for understanding how ozone works and why. When properly used as a real drug within therapeutic range, ozone therapy does not only does not procure adverse effects but yields a feeling of wellness. Half the book describes the value of ozone treatment in several diseases, particularly cutanious infection and vascular diseases where ozone really behaves as a “wonder drug”. The book has been written for clinical researchers, physicians and ozone therapists, but also for the layman or the patient interested in this therapy.

Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fourth Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 0071769420
Total Pages : 254 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fourth Edition by : Janet L. Stringer

Download or read book Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fourth Edition written by Janet L. Stringer and published by McGraw Hill Professional. This book was released on 2011-03-11 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: A time-saving, stress-reducing approach to learning the essential concepts of pharmacology Great for USMLE review! "This could be a very useful tool for students who struggle with understanding the most basic concepts in pharmacology for course and licensure examinations. 3 Stars."--Doody's Review Service Basic Concepts in Pharmacology provides you with a complete framework for studying -– and understanding -- the fundamental principles of drug actions. With this unique learning system, you’ll be able to identify must-know material, recognize your strengths and weaknesses, minimize memorization, streamline your study, and build your confidence. Basic Concepts in Pharmacology presents drugs by class, details exactly what you need to know about each class, and reinforces key concepts and definitions. With this innovative text you’ll be able to: Recognize the concepts you truly must know before moving on to other material Understand the fundamental principles of drug actions Organize and condense the drug information you must remember Review key information, which is presented in boxes, illustrations, and tables Identify the most important drugs in each drug class Seven sections specifically designed to simplify the learning process and help you gain an understanding of the most important concepts: General Principles Drugs That Affect the Autonomic Nervous System Drugs That Affect the Cardiovascular System Drugs That Act on the Central Nervous System Chemotherapeutic Agents Drugs That Affect the Endocrine System Miscellaneous Drugs (Includes Toxicology and Poisoning)

Perioperative Care of the Orthopedic Patient

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Publisher : Springer
ISBN 13 : 1461401003
Total Pages : 403 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Perioperative Care of the Orthopedic Patient by : C. Ronald MacKenzie

Download or read book Perioperative Care of the Orthopedic Patient written by C. Ronald MacKenzie and published by Springer. This book was released on 2014-08-01 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts at the top-ranked Hospital for Special Surgery in New York, Perioperative Care of the Orthopedic Patient is a comprehensive, multidisciplinary manual providing preoperative considerations, postoperative complications, and guidelines for the anesthetic and medical management of patients undergoing orthopedic surgery. Beginning with chapters covering preoperative evaluations and general principles and practices of perioperative medicine, the book then considers anesthesiologic management in orthopedic surgery and the role of postoperative pain management. This is followed by a section on medical management in specific clinical settings, discussing patients with connective tissue disease, cardiac disease, chronic pulmonary and renal diseases, diabetes and psychiatric and neurological diseases. A fourth section covers specific perioperative problems in orthopedic surgery, such as care of the elderly patient, venous thromboembolism, infection, nutrition, compartment syndrome, and bone health. Finally, the role of allied services, quality improvement and ethics are highlighted, and selected case studies are included to illustrate real-world perioperative issues and management strategies in orthopedic surgery. A comprehensive yet concise reference, Perioperative Care of the Orthopedic Patient will be an invaluable resource for orthopedic surgeons, sports medicine specialists and any professional involved in orthopedic surgery.

Dermatology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441905243
Total Pages : 375 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Dermatology by : Sima Jain

Download or read book Dermatology written by Sima Jain and published by Springer Science & Business Media. This book was released on 2012-03-29 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully-illustrated, note-packed volume of information, Dermatology: Illustrated Study Guide and Comprehensive Board Review fulfills a real need for a single study guide for the Dermatology Board Exam. Written by a previous Chief Resident of Dermatology at the University of Illinois at Chicago Medical Center, the text focuses on presenting comprehensive information in an easy-to-understand, easy-to-remember format. Tips, tricks, short lists, and tables fill every inch of this book—a must-have for any dermatology resident. Features: Acts as a concise go-to review book for the Dermatology Board Exam Hundreds of author notes pinpointing important information presented in an easy-to-read format Scores of mnemonics and memory tricks to mentally organize information Over 500 high-quality images placed parallel to the represented skin disorder Life after Boards—essential tips on coding and documentation

Mitochondrial Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1402067143
Total Pages : 446 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Mitochondrial Medicine by : Anna Gvozdjáková

Download or read book Mitochondrial Medicine written by Anna Gvozdjáková and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. This book is based on extensive data gathered over 30 years of clinical and experimental research. In it, internationally recognized authors share their experience in various fields of their expertise and guide readers through the disease process, from basic biochemical mechanisms to diagnosis to therapeutic aspects.