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Effect Of Excitatory Amino Acids On The In Vivo Release Of Superscript3h Adenosine Derivatives From The Cerebral Cortex And Cerebellum
Download Effect Of Excitatory Amino Acids On The In Vivo Release Of Superscript3h Adenosine Derivatives From The Cerebral Cortex And Cerebellum full books in PDF, epub, and Kindle. Read online Effect Of Excitatory Amino Acids On The In Vivo Release Of Superscript3h Adenosine Derivatives From The Cerebral Cortex And Cerebellum ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Effect of Excitatory Amino Acids on the in Vivo Release of Superscript3H-adenosine Derivatives from the Cerebral Cortex and Cerebellum by :
Download or read book Effect of Excitatory Amino Acids on the in Vivo Release of Superscript3H-adenosine Derivatives from the Cerebral Cortex and Cerebellum written by and published by . This book was released on 1978 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Excitatory Amino Acids and the Cerebral Cortex by : Fiorenzo Conti
Download or read book Excitatory Amino Acids and the Cerebral Cortex written by Fiorenzo Conti and published by MIT Press. This book was released on 1996 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has recently become clear that the excitatory amino acids and their receptors are critically linked to normal processes of development and synaptic transmission, and to learning and memory, as well as to identifiable disease processes such as Alzheimer's disease, epilepsy, and cortical damage due to stroke/ischemia. Moreover, the pharmacological nature and chemical structures of many of the receptors and binding sites for these synaptic mediators and their modulators are becoming known, thereby enabling the cloning of each receptor subtype. Such advances may help immeasurably in the identification of endogenous ligands for the amino acid receptors and the development of pharmaceuticals and other therapeutic interventions in coming years.
Book Synopsis Excitatory Amino Acids by : P.J. Roberts
Download or read book Excitatory Amino Acids written by P.J. Roberts and published by Springer. This book was released on 1986-06-18 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Excitatory Amino Acids and the Cerebral Cortex by : Fiorenzo Conti
Download or read book Excitatory Amino Acids and the Cerebral Cortex written by Fiorenzo Conti and published by . This book was released on 1996-08-07 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thirty original contributions in this book provide an up-to-date, interdisciplinary account of current research activity in all aspects of excitatory amino acid transmitters, particularly glutamate and aspartate, in the context of the structure and function of the cerebral cortex in health and in disease.It has recently become clear that the excitatory amino acids and their receptors are critically linked to normal processes of development and synaptic transmission, and to learning and memory, as well as to identifiable disease processes such as Alzheimer's disease, epilepsy, and cortical damage due to stroke/ischemia. Moreover, the pharmacological nature and chemical structures of many of the receptors and binding sites for these synaptic mediators and their modulators are becoming known, thereby enabling the cloning of each receptor subtype. Such advances may help immeasurably in the identification of endogenous ligands for the amino acid receptors and the development of pharmaceuticals and other therapeutic interventions in coming years.The topics are dealt with from electrophysiological, biochemical, anatomical, pharmacological, clinical, and behavioral perspectives to provide a thorough account of the functional roles played by these compounds in the part of the brain dealing with higher processes. The material is broad-based yet presented in a style that allows clinical and basic scientists alike easy access to integrated material across chapters and between sections.
Book Synopsis Excitatory Amino AcidsTheir Role in Neuroendocrine Function by : Darrell W. Brann
Download or read book Excitatory Amino AcidsTheir Role in Neuroendocrine Function written by Darrell W. Brann and published by CRC Press. This book was released on 1995-10-24 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication focuses on the neuroendocrine functions of excitatory neurotransmitters in the brain known as the excitatory amino acid transmitters (EAAs). EEAs, such as glutamate and aspartate, regulate the release of pituitary hormones which in-turn effect most of the physiological systems in the body. This book gives detailed coverage of the role of EAAs in reproduction, growth, the stress axis, seasonal breeding, puberty, learning, and memory.
Book Synopsis Effect of Oxidative Stress on Excitatory Amino Acid Release by Cerebral Cortical Synaptosomes by :
Download or read book Effect of Oxidative Stress on Excitatory Amino Acid Release by Cerebral Cortical Synaptosomes written by and published by . This book was released on 1993 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous studies in our laboratory have suggested that an oxidation reaction is responsible for the actions of free radicals to decrease synaptic potentials. Recently we observed that free radicals both decreased depolarization-induced vesicular release and enhanced basal, nonvesicular release of the excitatory amino acid, (3H)L-glutamate. In order to evaluate the contribution of oxidative reactions to this latter effect, we evaluated the actions of the oxidizing agent chloramine-T on synaptosomal release of excitatory amino acids, using (3H)D-aspartate as the exogenous label. Basal and depolarization evoked (3H)D-aspartate release were calcium-independent and nonvesicular. Chloramine-T pretreatment significantly increased basal release, while having no effect on high K+-evoked release. These data suggest that an oxidative process can mimic the free radical increase of basal release, as well as the decrease in synaptic potentials. On the other hand, the calcium- independent-evoked release may involve a different mechanism. Our results demonstrate that under basal, nondepolarizing conditions, oxidative stress exerts an adverse effect on the presynaptic nerve terminal, resulting in an increased release of potentially damaging excitatory amino acid neurotransmitters.
