Effect of Calcium Channel Blockers on the Incidence of Restenosis After Coronary Balloon Angioplasty and on the Progression of Coronary Artery Disease

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Publisher : Leuven University Press
ISBN 13 : 9789058672988
Total Pages : 172 pages
Book Rating : 4.6/5 (729 download)

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Book Synopsis Effect of Calcium Channel Blockers on the Incidence of Restenosis After Coronary Balloon Angioplasty and on the Progression of Coronary Artery Disease by : Joseph Dens

Download or read book Effect of Calcium Channel Blockers on the Incidence of Restenosis After Coronary Balloon Angioplasty and on the Progression of Coronary Artery Disease written by Joseph Dens and published by Leuven University Press. This book was released on 2003-09 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nisoldipine, In-vitro effects of calcium channel blockers in reducing restenosis after balloon angioplasty and in retarding the progression of atherosclerosis, Usefulness of nisoldipine for prevention of restenosis after percutaneous transluminal coronary angioplasty, An updated meta-analysis of calcium channel blockers in the prevention of restenosis after coronary angioplasty, Late angiographic follow-up of dilated coronary lesions, Long-term effects of nioldipine on the progression of coronary atherosclerosis and the occurrence of clinical events: the NICOLE study, General Discussion, Final Conclusions and further directions."

Multiple Approaches to Inhibit Restenosis After Percutaneous Coronary Interventions

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Publisher : Leuven University Press
ISBN 13 : 9789058674432
Total Pages : 190 pages
Book Rating : 4.6/5 (744 download)

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Book Synopsis Multiple Approaches to Inhibit Restenosis After Percutaneous Coronary Interventions by : Xiaoshun Liu

Download or read book Multiple Approaches to Inhibit Restenosis After Percutaneous Coronary Interventions written by Xiaoshun Liu and published by Leuven University Press. This book was released on 2004 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. Restenosis occurs in 10-50% of patients after PCI, thus remaining a major challenge. Restenosis after PCI is a complex, multifactorial, overlapping wound healing process involving a cascade of cellular and molecular events including platelet activation, inflammatory cell infiltration, smooth muscle cell proliferation, migration and extracellular matrix production. Recent evidence shows that inflammation, matrix metalloproteinases and free oxygen radicals all play a critical role in the restenosis process. Different approaches to prevent restenosis after PCI were studied in this work. Restenosis has been remarkably reduced in the last decade with the introduction of stents. Stents have been optimized regarding their mechanical features, allowing for scaffolding of the plaque and producing an optimal coronary lumen at the end of the procedure. By their metallic nature however, they cause prolonged and chronic inflammation in the vessel wall. Therefore, the long term efficacy remains a concern. In the first study, the author evaluated the long-term follow-up of patients that underwent bare metal stent implantation. The long-term efficacy of this stent was established, and the major adverse cardiac events (MACE) during the long-term follow-up were mainly caused by progression of lesions in other vessels. This study confirmed that implantation of a bare metal stent in an effective treatment modality of atherosclerotic coronary disease. However, in-stent restenosis still results in a failure of this treatment in about 30% of the patients, mostly occurring within the first 6 months.

Structure-Function Relationship and Modulation of the T-type Calcium Channel 1G

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Publisher : Leuven University Press
ISBN 13 : 9789058673824
Total Pages : 134 pages
Book Rating : 4.6/5 (738 download)

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Book Synopsis Structure-Function Relationship and Modulation of the T-type Calcium Channel 1G by : Karel Talavera Perez

Download or read book Structure-Function Relationship and Modulation of the T-type Calcium Channel 1G written by Karel Talavera Perez and published by Leuven University Press. This book was released on 2004-09 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Eluting Stents

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Publisher : Leuven University Press
ISBN 13 : 9789058673275
Total Pages : 154 pages
Book Rating : 4.6/5 (732 download)

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Book Synopsis Drug Eluting Stents by : Yanming Huang

Download or read book Drug Eluting Stents written by Yanming Huang and published by Leuven University Press. This book was released on 2003-11 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. Role of Inflammation in the Pathogenesis of Restenosis, Local Drug Delivery Using Drug Eluting Stents, In Vitro Stent Implantation, Optimization of Local Methylprednisolone Delivery to Inhibit Inflammatory Reaction and Neointimal Hyperplasia of Coated Coronary Stents, Cytochalasin Polymer Coated Stents Reduce Neointimal Formation in a Porcine Coronary Model, Long-Term Biocompatibility Evaluation of a Biodegradable Polymer Coated Stent in a Porcine Coronary Stent Model, Methotrexate Loaded SAE-Coated Coronary Stents Reduce Neointimal Hyperplasia in a Porcine Coronary Model, Local Methylprednisolone Delivery Using a Biodivysio Phosphorycholone Coated Drug Delivery Stents Reduces Inflammation and Neointimal Hyperplasia in a Porcine Coronary Stent Model, Stent Based Dexamethasone Delivery: From Pre-Clinical Data to the Stride Trial, General Discussions and Conclusions."

Structure-function Relationship of K+ Ion Channel Toxins

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Publisher : Leuven University Press
ISBN 13 : 9789058673534
Total Pages : 240 pages
Book Rating : 4.6/5 (735 download)

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Book Synopsis Structure-function Relationship of K+ Ion Channel Toxins by : Isabelle Huys

Download or read book Structure-function Relationship of K+ Ion Channel Toxins written by Isabelle Huys and published by Leuven University Press. This book was released on 2004 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. Many fundamental processes underlying nerve and muscle excitation, hormone secretion, learning and memory, cell proliferation, sensory transduction and regulation of blood pressure and osmotic balance, are attributed to a div"

The Effects of 1,25-Dihydroxyvitamin D3 and Analogues on UVB-irradiated Human Keratinocytes

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Publisher : Leuven University Press
ISBN 13 : 9789058674289
Total Pages : 178 pages
Book Rating : 4.6/5 (742 download)

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Book Synopsis The Effects of 1,25-Dihydroxyvitamin D3 and Analogues on UVB-irradiated Human Keratinocytes by : Petra De Haes

Download or read book The Effects of 1,25-Dihydroxyvitamin D3 and Analogues on UVB-irradiated Human Keratinocytes written by Petra De Haes and published by Leuven University Press. This book was released on 2004 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. The skin serves as a protective interface between the body and the noxious environment. Ultraviolet (UV) radiation is one of the most important sources of environmental stress, inducing photochemical changes in the skin that may lead to sunburn, premature skin aging and skin cancer. The skin and UV also play a leading part in the vitamin D endocrine system. When UVB photons strike the epidermis, their energy can be used for the synthesis of vitamin D3. Furthermore, the skin is one of the direct target issues for vitamin D3 action. The close interplay between UV and vitamin D3 production in the skin evokes the possibility of mutual interactions. Contents: Introduction, Aims and Scopes of the Study, Materials and Methods, 1,25D3 Inhibits UVB-Induced Apoptosis and IL-6 Production in Human Keratinocytes, 1,25D3 Protects Human Keratinocytes Against UVB-Induced Damage, Two 14-EPI Analogues of 1,25D3 Protect Human Keratinocytes Against Different UVB Effects, Molecular Pathways Involved in the Anti-Apoptotic Effect of 1,25D3 in Human Keratinocytes, General Discussion and Perspectives.

Domestic Environment and Lifestyle Determinants of Asthma in Palestinian Children

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Publisher : Leuven University Press
ISBN 13 : 9789058673183
Total Pages : 174 pages
Book Rating : 4.6/5 (731 download)

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Book Synopsis Domestic Environment and Lifestyle Determinants of Asthma in Palestinian Children by : Nuha El Sharif

Download or read book Domestic Environment and Lifestyle Determinants of Asthma in Palestinian Children written by Nuha El Sharif and published by Leuven University Press. This book was released on 2003-11 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs

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Publisher : Leuven University Press
ISBN 13 : 9789058674753
Total Pages : 206 pages
Book Rating : 4.6/5 (747 download)

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Book Synopsis Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs by : Guy Eelen

Download or read book Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs written by Guy Eelen and published by Leuven University Press. This book was released on 2005 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Generation and Characterization of a Mouse Model for a Sodium Channel Based Long QT Syndrome (LQT3)

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Publisher : Leuven University Press
ISBN 13 : 9789058675309
Total Pages : 142 pages
Book Rating : 4.6/5 (753 download)

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Book Synopsis Generation and Characterization of a Mouse Model for a Sodium Channel Based Long QT Syndrome (LQT3) by : Dieter Nuyens

Download or read book Generation and Characterization of a Mouse Model for a Sodium Channel Based Long QT Syndrome (LQT3) written by Dieter Nuyens and published by Leuven University Press. This book was released on 2006 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Duodenal Calcium Absorption and Steroid Hormones

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Publisher : Leuven University Press
ISBN 13 : 9789058674470
Total Pages : 170 pages
Book Rating : 4.6/5 (744 download)

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Book Synopsis Duodenal Calcium Absorption and Steroid Hormones by : Sophie Van Cromphaut

Download or read book Duodenal Calcium Absorption and Steroid Hormones written by Sophie Van Cromphaut and published by Leuven University Press. This book was released on 2004 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. The aim of this thesis was to understand the role of 1,25(OH)2D3 and other steroid hormones in the regulation of active duodenal calcium absorption. To achieve this aim, the authors analyzed active duodenal calcium absorption at molecular and functional level. Contents include: Introduction: Calcium, The vitamin D endocrine system, Calcium (re)absorption, Active calcium absorption, vitamin D independent mechanisms; Aims and Scope of the study; Vitamin D dependent active duodenal calcium absorption; Active calcium absorption throughout the female reproductive cycle; The contribution of altered active absorption to the pathogenesis of glucocorticoid-induced bone loss; Discussion; Summary; Perspectives.

A Prospective Study of Risk Factors for Low Back Disorders in Occupational Settings

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Publisher : Leuven University Press
ISBN 13 : 9789058674951
Total Pages : 168 pages
Book Rating : 4.6/5 (749 download)

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Book Synopsis A Prospective Study of Risk Factors for Low Back Disorders in Occupational Settings by : An van Nieuwenhuyse

Download or read book A Prospective Study of Risk Factors for Low Back Disorders in Occupational Settings written by An van Nieuwenhuyse and published by Leuven University Press. This book was released on 2005 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Between Facts and Norms

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Publisher : Leuven University Press
ISBN 13 : 9789058674944
Total Pages : 224 pages
Book Rating : 4.6/5 (749 download)

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Book Synopsis Between Facts and Norms by : Pascal Borry

Download or read book Between Facts and Norms written by Pascal Borry and published by Leuven University Press. This book was released on 2005 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Modulation of CFTR and ENaC Channel Function by Interacting Proteins and Trafficking

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Publisher : Leuven University Press
ISBN 13 : 9789058675101
Total Pages : 140 pages
Book Rating : 4.6/5 (751 download)

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Book Synopsis Modulation of CFTR and ENaC Channel Function by Interacting Proteins and Trafficking by : Lishuang Cao

Download or read book Modulation of CFTR and ENaC Channel Function by Interacting Proteins and Trafficking written by Lishuang Cao and published by Leuven University Press. This book was released on 2005 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell Repopulation of Bioprosthetic Heart Valves

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Publisher : Leuven University Press
ISBN 13 : 9789058675477
Total Pages : 156 pages
Book Rating : 4.6/5 (754 download)

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Book Synopsis Cell Repopulation of Bioprosthetic Heart Valves by : Jessa Yperman

Download or read book Cell Repopulation of Bioprosthetic Heart Valves written by Jessa Yperman and published by Leuven University Press. This book was released on 2006 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Growth Hormone- and Insulin-induced Alterations in Metabolism During Critical Illness

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Publisher : Leuven University Press
ISBN 13 : 9789058673466
Total Pages : 212 pages
Book Rating : 4.6/5 (734 download)

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Book Synopsis Mechanisms of Growth Hormone- and Insulin-induced Alterations in Metabolism During Critical Illness by : Dieter Mesotten

Download or read book Mechanisms of Growth Hormone- and Insulin-induced Alterations in Metabolism During Critical Illness written by Dieter Mesotten and published by Leuven University Press. This book was released on 2003 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. In this thesis attention will be focuses on the mechanisms by which growth hormone and insulin modify some major metabolic pathways, in light of their opposite effects on outcome of critical iliness. Chapter 1 comprises a bri"

Fetal Membrane Healing

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Publisher : Leuven University Press
ISBN 13 : 9789058673206
Total Pages : 190 pages
Book Rating : 4.6/5 (732 download)

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Book Synopsis Fetal Membrane Healing by : Roland Devlieger

Download or read book Fetal Membrane Healing written by Roland Devlieger and published by Leuven University Press. This book was released on 2003-11 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NuSAP, a Novel Microtubule-Associated Protein Involved in Mitotic Spindle Organization

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Publisher : Leuven University Press
ISBN 13 : 9789058673039
Total Pages : 140 pages
Book Rating : 4.6/5 (73 download)

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Book Synopsis NuSAP, a Novel Microtubule-Associated Protein Involved in Mitotic Spindle Organization by : Tim Raemaekers

Download or read book NuSAP, a Novel Microtubule-Associated Protein Involved in Mitotic Spindle Organization written by Tim Raemaekers and published by Leuven University Press. This book was released on 2003-09 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Vitamin D and bone, Linking the fields of vitamin D and bone with those of the nucleus and mitotic spindle, Nucleus structure and dynamics, Organization of the nucleus, Microtubules and associated proteins, Mitosis and spindle assembly, Control and mechanism of spindle formation and dynamics, Materials and methods, NuSAP, and novel MAP involved in spindle organization, NuSAP expression in cultured osteoblasts: regulation during development and by 1,25-dihydroxyvitamin D3, Analysis of NuSAP gene expression at the tissue level and chromosomal localization of human and mouse NuSAP, Developmentally regulated expression of NuSAP in the rat testis and mouse embryo, Chromosomal localization of human and mouse Nusap, General discussion and perspectives."