Drugs Do Not Discriminate (paperback)

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Author :
Publisher : Lulu.com
ISBN 13 : 1326822470
Total Pages : 156 pages
Book Rating : 4.3/5 (268 download)

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Book Synopsis Drugs Do Not Discriminate (paperback) by : Glenn Munso

Download or read book Drugs Do Not Discriminate (paperback) written by Glenn Munso and published by Lulu.com. This book was released on with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drugs Are Not the Devil's Tools - Vol.2, Black & White Edition: How Discrimination and Greed Created a Dysfunctional Drug Policy and How It Can Be Fix

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Publisher :
ISBN 13 : 9781883423339
Total Pages : 270 pages
Book Rating : 4.4/5 (233 download)

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Book Synopsis Drugs Are Not the Devil's Tools - Vol.2, Black & White Edition: How Discrimination and Greed Created a Dysfunctional Drug Policy and How It Can Be Fix by : David Bearman M D

Download or read book Drugs Are Not the Devil's Tools - Vol.2, Black & White Edition: How Discrimination and Greed Created a Dysfunctional Drug Policy and How It Can Be Fix written by David Bearman M D and published by . This book was released on 2015-04-12 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Drugs are NOT the Devil’s Tools is a[n] ... examination into the origin of United States drug laws. Dr. David Bearman shows how, through intertwining motives of discrimination and greed, often under the guise of morality, they have created a drug policy that is completely dysfunctional. As he points out, our drug laws have been very effective in further marginalizing discriminated-against groups and a total failure in every other respect. In his new book, Dr. Bearman shows that there has rarely been a civilization in the history of mankind that has not used some form of man-altering substance. He also demonstrates that the very real medical properties of cannabis were recognized thousands of years ago, as were the medicinal uses of opium, coca, alcohol and spices..."--Back cover.

Ending Discrimination Against People with Mental and Substance Use Disorders

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Author :
Publisher : National Academies Press
ISBN 13 : 0309439124
Total Pages : 171 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Ending Discrimination Against People with Mental and Substance Use Disorders by : National Academies of Sciences, Engineering, and Medicine

Download or read book Ending Discrimination Against People with Mental and Substance Use Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-09-03 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Estimates indicate that as many as 1 in 4 Americans will experience a mental health problem or will misuse alcohol or drugs in their lifetimes. These disorders are among the most highly stigmatized health conditions in the United States, and they remain barriers to full participation in society in areas as basic as education, housing, and employment. Improving the lives of people with mental health and substance abuse disorders has been a priority in the United States for more than 50 years. The Community Mental Health Act of 1963 is considered a major turning point in America's efforts to improve behavioral healthcare. It ushered in an era of optimism and hope and laid the groundwork for the consumer movement and new models of recovery. The consumer movement gave voice to people with mental and substance use disorders and brought their perspectives and experience into national discussions about mental health. However over the same 50-year period, positive change in American public attitudes and beliefs about mental and substance use disorders has lagged behind these advances. Stigma is a complex social phenomenon based on a relationship between an attribute and a stereotype that assigns undesirable labels, qualities, and behaviors to a person with that attribute. Labeled individuals are then socially devalued, which leads to inequality and discrimination. This report contributes to national efforts to understand and change attitudes, beliefs and behaviors that can lead to stigma and discrimination. Changing stigma in a lasting way will require coordinated efforts, which are based on the best possible evidence, supported at the national level with multiyear funding, and planned and implemented by an effective coalition of representative stakeholders. Ending Discrimination Against People with Mental and Substance Use Disorders: The Evidence for Stigma Change explores stigma and discrimination faced by individuals with mental or substance use disorders and recommends effective strategies for reducing stigma and encouraging people to seek treatment and other supportive services. It offers a set of conclusions and recommendations about successful stigma change strategies and the research needed to inform and evaluate these efforts in the United States.

Drug Dealer, MD

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Publisher : JHU Press
ISBN 13 : 1421421402
Total Pages : 187 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Drug Dealer, MD by : Anna Lembke

Download or read book Drug Dealer, MD written by Anna Lembke and published by JHU Press. This book was released on 2016-11-15 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: The disturbing connection between well-meaning physicians and the prescription drug epidemic. Three out of four people addicted to heroin probably started on a prescription opioid, according to the director of the Centers for Disease Control and Prevention. In the United States alone, 16,000 people die each year as a result of prescription opioid overdose. But perhaps the most frightening aspect of the prescription drug epidemic is that it’s built on well-meaning doctors treating patients with real problems. In Drug Dealer, MD, Dr. Anna Lembke uncovers the unseen forces driving opioid addiction nationwide. Combining case studies from her own practice with vital statistics drawn from public policy, cultural anthropology, and neuroscience, she explores the complex relationship between doctors and patients, the science of addiction, and the barriers to successfully addressing drug dependence and addiction. Even when addiction is recognized by doctors and their patients, she argues, many doctors don’t know how to treat it, connections to treatment are lacking, and insurance companies won’t pay for rehab. Full of extensive interviews—with health care providers, pharmacists, social workers, hospital administrators, insurance company executives, journalists, economists, advocates, and patients and their families—Drug Dealer, MD, is for anyone whose life has been touched in some way by addiction to prescription drugs. Dr. Lembke gives voice to the millions of Americans struggling with prescription drugs while singling out the real culprits behind the rise in opioid addiction: cultural narratives that promote pills as quick fixes, pharmaceutical corporations in cahoots with organized medicine, and a new medical bureaucracy focused on the bottom line that favors pills, procedures, and patient satisfaction over wellness. Dr. Lembke concludes that the prescription drug epidemic is a symptom of a faltering health care system, the solution for which lies in rethinking how health care is delivered.

Drug Use for Grown-Ups

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Author :
Publisher : Penguin
ISBN 13 : 1101981660
Total Pages : 305 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Drug Use for Grown-Ups by : Dr. Carl L. Hart

Download or read book Drug Use for Grown-Ups written by Dr. Carl L. Hart and published by Penguin. This book was released on 2022-01-11 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Hart’s argument that we need to drastically revise our current view of illegal drugs is both powerful and timely . . . when it comes to the legacy of this country’s war on drugs, we should all share his outrage.” —The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy life Dr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a researcher and professor, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism. Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars. Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.

Not In Vain

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Author :
Publisher : Independently Published
ISBN 13 :
Total Pages : 800 pages
Book Rating : 4.6/5 (893 download)

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Book Synopsis Not In Vain by : Bobbie R Ziemer

Download or read book Not In Vain written by Bobbie R Ziemer and published by Independently Published. This book was released on 2020-10-27 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: We never think that OUR CHILD will be labeled an "addict." From the moment of their birth, we taught them love, compassion, sharing, hope, manners, patience, faith, and so many more qualities to live by, only wanting them to flourish as a better version of ourselves. When we learn that our child has been using drugs, our minds seem to immediately compare our own youth when drinking or maybe even smoking marijuana. Unfortunately, this is the furthest comparison from the reality of what's ahead. This book is filled with over 160 real-life stories from grieving mothers through our initial discovery of our child's drug use to the devastating end of their journey. We have shared what we have learned, the emotional ups-and-downs, the "enabling," "tough love," "unconditional love," the effect within ourselves and our family, and what we wished we would have known or even done differently. Nobody wants to talk about it when it's happening to them or how families are completely lost when fighting this disease. We believe that these real-life stories will further awareness and help provide comfort and navigation to those who are struggling. You are not alone. By sharing our stories, others will see many of the same struggles and situations mothers have lived as well as the resources we have found along the way. This book is our opportunity to share the painful experiences mamas have endured to help and guide those on the same journey. Although this book sadly cannot bring our children back from the tragic loss resulting from the drug pandemic, perhaps these stories from real mothers who have survived this loss can help you understand and guide you through the most challenging situation that anyone could possibly have even considered-the loss of their child. This book will not provide you with "professional" guidance; however, you will be able to see a small view into this painful journey that us grieving mothers of this pandemic now carry as a life sentence. Lastly, this book is devoted to all the precious children we have lost and to all mothers who are struggling to survive this devastating loss; to the families still fighting for the life of their children. May these stories give you hope and insight, and may God give you strength to never give up.

Medications for Opioid Use Disorder Save Lives

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Author :
Publisher : National Academies Press
ISBN 13 : 0309486483
Total Pages : 175 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Medications for Opioid Use Disorder Save Lives by : National Academies of Sciences, Engineering, and Medicine

Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Slaying the Dragon: The History of Addiction Treatment and Recovery in America

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Author :
Publisher :
ISBN 13 : 9780692213469
Total Pages : 558 pages
Book Rating : 4.2/5 (134 download)

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Book Synopsis Slaying the Dragon: The History of Addiction Treatment and Recovery in America by : William L. White

Download or read book Slaying the Dragon: The History of Addiction Treatment and Recovery in America written by William L. White and published by . This book was released on 2014-07-01 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is the remarkable story of America's personal and instituional responses to alcoholism and other addictions. It is the story of mutual aid societies: the Washingtonians, the Blue Ribbon Reform Clubs, the Ollapod Club, the United Order of Ex-Boozers, the Jacoby Club, Alcoholics Anonymous and Women for Sobriety. It is a story of addiction treatment institutions from the inebriate asylums and Keeley Institutes to Hazelden and Parkside. It is the story of evolving treatment interventions that range from water cures and mandatory sterilization to aversion therapies and methadone maintenance. William White has provided a sweeping and engaging history of one of America's most enduring problems and the profession that was birthed to respond to it" -- BACK COVER.

Breaking Night

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Publisher : Hachette Books
ISBN 13 : 1401396208
Total Pages : 363 pages
Book Rating : 4.4/5 (13 download)

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Book Synopsis Breaking Night by : Liz Murray

Download or read book Breaking Night written by Liz Murray and published by Hachette Books. This book was released on 2010-09-07 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the vein of The Glass Castle, Breaking Night is the stunning memoir of a young woman who at age fifteen was living on the streets, and who eventually made it into Harvard. Liz Murray was born to loving but drug-addicted parents in the Bronx. In school she was taunted for her dirty clothing and lice-infested hair, eventually skipping so many classes that she was put into a girls' home. At age fifteen, Liz found herself on the streets. She learned to scrape by, foraging for food and riding subways all night to have a warm place to sleep. When Liz's mother died of AIDS, she decided to take control of her own destiny and go back to high school, often completing her assignments in the hallways and subway stations where she slept. Liz squeezed four years of high school into two, while homeless; won a New York Times scholarship; and made it into the Ivy League. Breaking Night is an unforgettable and beautifully written story of one young woman's indomitable spirit to survive and prevail, against all odds.

Nonclinical Assessment of Abuse Potential for New Pharmaceuticals

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Publisher : Academic Press
ISBN 13 : 0124202160
Total Pages : 321 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis Nonclinical Assessment of Abuse Potential for New Pharmaceuticals by : Carrie Markgraf

Download or read book Nonclinical Assessment of Abuse Potential for New Pharmaceuticals written by Carrie Markgraf and published by Academic Press. This book was released on 2015-07-14 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy

2018 CFR e-Book Title 14, Aeronautics and Space, Parts 1200-End

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Author :
Publisher : IntraWEB, LLC and Claitor's Law Publishing
ISBN 13 :
Total Pages : 396 pages
Book Rating : 4./5 ( download)

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Book Synopsis 2018 CFR e-Book Title 14, Aeronautics and Space, Parts 1200-End by : Office of The Federal Register

Download or read book 2018 CFR e-Book Title 14, Aeronautics and Space, Parts 1200-End written by Office of The Federal Register and published by IntraWEB, LLC and Claitor's Law Publishing. This book was released on 2018-01-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Title 14, Aeronautics and Space, Parts 1200-End

The New Jim Crow

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Publisher : The New Press
ISBN 13 : 1620971941
Total Pages : 434 pages
Book Rating : 4.6/5 (29 download)

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Book Synopsis The New Jim Crow by : Michelle Alexander

Download or read book The New Jim Crow written by Michelle Alexander and published by The New Press. This book was released on 2020-01-07 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Named one of the most important nonfiction books of the 21st century by Entertainment Weekly‚ Slate‚ Chronicle of Higher Education‚ Literary Hub, Book Riot‚ and Zora A tenth-anniversary edition of the iconic bestseller—"one of the most influential books of the past 20 years," according to the Chronicle of Higher Education—with a new preface by the author "It is in no small part thanks to Alexander's account that civil rights organizations such as Black Lives Matter have focused so much of their energy on the criminal justice system." —Adam Shatz, London Review of Books Seldom does a book have the impact of Michelle Alexander's The New Jim Crow. Since it was first published in 2010, it has been cited in judicial decisions and has been adopted in campus-wide and community-wide reads; it helped inspire the creation of the Marshall Project and the new $100 million Art for Justice Fund; it has been the winner of numerous prizes, including the prestigious NAACP Image Award; and it has spent nearly 250 weeks on the New York Times bestseller list. Most important of all, it has spawned a whole generation of criminal justice reform activists and organizations motivated by Michelle Alexander's unforgettable argument that "we have not ended racial caste in America; we have merely redesigned it." As the Birmingham News proclaimed, it is "undoubtedly the most important book published in this century about the U.S." Now, ten years after it was first published, The New Press is proud to issue a tenth-anniversary edition with a new preface by Michelle Alexander that discusses the impact the book has had and the state of the criminal justice reform movement today.

Employee Benefits Answer Book

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Author :
Publisher : Wolters Kluwer
ISBN 13 : 1454855932
Total Pages : 1682 pages
Book Rating : 4.4/5 (548 download)

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Book Synopsis Employee Benefits Answer Book by : Dorinda D. DeScherer

Download or read book Employee Benefits Answer Book written by Dorinda D. DeScherer and published by Wolters Kluwer. This book was released on 2015-06-09 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Employee Benefits Answer Book provides comprehensive guidance for those involved in the design and administration of employee benefit plans. The Q&A format is ideal for probing key topics such as: Health care reform COBRA continuation coverage Retiree health care coverage Health coverage portability requirements Group long-term care insurance Dependent care assistance Adoption assistance Vacation and severance pay plans Death benefits Financing employee benefits Financial accounting for employee benefits And more! Employee Benefits Answer Book will help you: Set the best Health Care Reform strategy for your company and your clients Keep in compliance with current and coming requirements Find clear answers to hundreds of employee benefits questions Avoid costly errors related to employee benefits administration Resolve employee benefits issues quickly and effectively And much more! The Thirteenth Edition provides up-to-date coverage of the Affordable Care Act (ACA), including: Transition rules leading to full implementation of the employer shared responsibility requirements in 2015 Guidance on when employer-provided health coverage provides minimum value Latest figures for determining affordability of employer-provided health coverage Rules governing the interplay of orientation periods with the new limits on waiting periods for health coverage And more! Additionally Employee Benefits Answer Book has been updated to include discussions of: New guidance on stop-loss insurance The Supreme Court’s weighing in on vesting of retiree health benefits Final regulations on payment of retiree health premiums by a pension or annuity plan DOL issuance of updated COBRA continuation coverage notices that reflect the Health Exchange option And more!

Saving Jake

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Publisher : Focusup Books
ISBN 13 : 9780996254304
Total Pages : 314 pages
Book Rating : 4.2/5 (543 download)

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Book Synopsis Saving Jake by : D'Anne Burwell

Download or read book Saving Jake written by D'Anne Burwell and published by Focusup Books. This book was released on 2015-08-27 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: D'Anne Burwell's smart, athletic son-raised in a loving and prosperous home-begins abusing OxyContin as a teenager, and within a year drops out of college, walks out of rehab, and lands homeless on the streets of Boulder. Struggling with fear, guilt, and a desperate need to protect her son, D'Anne grapples with her husband's anger and her daughter's depression as the family disease of addiction impacts them all. She discovers the terrifying links between prescription-drug abuse and skyrocketing heroin use. And she comes to understand that to save her child she must step back and allow him to fight for his own soul. SAVING JAKE gives voice to the devastation shared by the families of addicts, and provides vital hope. Above all, it is a powerful personal story of love and redemption.

Discrimination and Disparities

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Author :
Publisher : Basic Books
ISBN 13 : 1541617835
Total Pages : 320 pages
Book Rating : 4.5/5 (416 download)

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Book Synopsis Discrimination and Disparities by : Thomas Sowell

Download or read book Discrimination and Disparities written by Thomas Sowell and published by Basic Books. This book was released on 2019-03-05 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: An enlarged edition of Thomas Sowell's brilliant examination of the origins of economic disparities Economic and other outcomes differ vastly among individuals, groups, and nations. Many explanations have been offered for the differences. Some believe that those with less fortunate outcomes are victims of genetics. Others believe that those who are less fortunate are victims of the more fortunate. Discrimination and Disparities gathers a wide array of empirical evidence to challenge the idea that different economic outcomes can be explained by any one factor, be it discrimination, exploitation, or genetics. This revised and enlarged edition also analyzes the human consequences of the prevailing social vision of these disparities and the policies based on that vision--from educational disasters to widespread crime and violence.

Rang & Dale's Pharmacology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0702054976
Total Pages : 785 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Rang & Dale's Pharmacology by : James M. Ritter

Download or read book Rang & Dale's Pharmacology written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2014-12-02 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: For 25 years, Rang and Dale’s Pharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide. Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at studentconsult.com. Consult this title on your favorite e-reader. Get the essential pharmacology information you need from one authoritative source with an outstanding global reputation for excellence. Progress confidently through all relevant aspects of pharmacology, beginning with a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs. Find important content quickly thanks to a color-coded layout that enables easy navigation and cross-referencing. Master difficult concepts with Key Points boxes, Clinical Uses boxes, and full-color illustrations throughout. Stay up to date with new information in the field, including an all-new chapter on drugs that affect the skin. Take advantage of new and unique features online, including 500+ chapter-specific multiple choice questions for immediate self-assessment. eBook version included! For the first time, you can access the entire book online or offline across all devices with the Student Consult eBook!

Brody's Human Pharmacology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323846742
Total Pages : 798 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Brody's Human Pharmacology by : Lynn Wecker

Download or read book Brody's Human Pharmacology written by Lynn Wecker and published by Elsevier Health Sciences. This book was released on 2024-02-02 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals. Contains all the essential aspects of pharmacology – suitable for exam preparation Full color illustrations explain important processes and color-coded boxes enhance understanding Therapeutic overviews, clinical problems and trade names – everything you need to know Self-assessment questions and further reading to reinforce learning Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life Updated content throughout Pharmacodynamics chapter revised to include discussions of positive and negative allosteric modulators, as well as biased agonism Pharmacogenetics chapter considers genetic variations and their relationship to drug responses Section on cancer drugs revised to reflect major advances New chapter on immunological and cell-based therapies