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Drugs And Aging
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Book Synopsis Anti-aging Drugs by : Alexander M Vaiserman
Download or read book Anti-aging Drugs written by Alexander M Vaiserman and published by Royal Society of Chemistry. This book was released on 2017-02-01 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.
Download or read book Drugs and Aging written by Dieter Platt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental gerontological research is necessary to obtain optimal information and thus ensure proper drug therapy for the elderly. Most older persons acquire multiple diseases, first of all chronic diseases. They involve complex problems of a physical, social, and psychological nature. The multimorbidity of the elderly raises many questions in drug therapy. By contrast with our extensive knowledge of pharmacokinetics and pharmacodynamics in younger age groups, few facts are available in respect of the elderly. A variety of factors may influence drug therapy. Physiological and pathological age-related changes of molecules, cells, organs, and the total organism may interact to enhance or inhibit drug therapy in higher age groups. It is well known that elderly patients are overmedicated and therefore the incidence of adverse drug reactions increases with age. Elderly patients with multimorbidity often have a diminished body clearance of drugs; age-related changes of the kidney seems to be one of the most important factors in this regard. Far less important than the elimination of drugs through the kidney is their excretion in the bile. So far results have disclosed that oxidative steps in drug clearance are more likely to be disturbed than phase II reactions. Furthermore; changes in distribution volume and age-related alterations in receptor sensitivity also influence the clearance of drugs in the elderly.
Author :G. Barbagallo-Sangiorgi Publisher :Springer Science & Business Media ISBN 13 :1461327911 Total Pages :517 pages Book Rating :4.4/5 (613 download)
Book Synopsis Aging and Drug Therapy by : G. Barbagallo-Sangiorgi
Download or read book Aging and Drug Therapy written by G. Barbagallo-Sangiorgi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the greatest advances in Geriatric Medicine during the last quarter of a century has been the increased realization of the possibilities of treatment for elderly patients. Neglect has been replaced by a more optimistic therapeutic endeavour and countless old people have benefitted from this approach. But there is also a drawback, and this is the risk of hazardous side effects of medication which are often directly proportional to the biological potency of the drug and may be unpredictably increased due to changes in the senile organism. In fact the anatomical and biological changes in old age alter both the kinetics of most drugs and the receptor response. On account of these changes the individual tolerance of aged patients to drug therapy may be quite different from that of younger subjects. Thus for a variety of reasons elderly patients receive more drugs, but they are at a higher risk of encountering adverse reactions, which often show atypical clinical features. We can therefore speak of "geriatric iatrogenic disorders" and point out that some of these side effects are determined by a complex pathogenesis due to the particular pathophysiological condition in the elderly. It is important to encourage the habit of individ ually evaluating potential risk versus expected advantages of drugs in keeping with the same principles adopted in the evaluation of cost/benefit ratio.
Book Synopsis Aging and Drug Therapy by : G. Barbagallo-Sangiorgi
Download or read book Aging and Drug Therapy written by G. Barbagallo-Sangiorgi and published by Springer. This book was released on 2011-11-04 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the greatest advances in Geriatric Medicine during the last quarter of a century has been the increased realization of the possibilities of treatment for elderly patients. Neglect has been replaced by a more optimistic therapeutic endeavour and countless old people have benefitted from this approach. But there is also a drawback, and this is the risk of hazardous side effects of medication which are often directly proportional to the biological potency of the drug and may be unpredictably increased due to changes in the senile organism. In fact the anatomical and biological changes in old age alter both the kinetics of most drugs and the receptor response. On account of these changes the individual tolerance of aged patients to drug therapy may be quite different from that of younger subjects. Thus for a variety of reasons elderly patients receive more drugs, but they are at a higher risk of encountering adverse reactions, which often show atypical clinical features. We can therefore speak of "geriatric iatrogenic disorders" and point out that some of these side effects are determined by a complex pathogenesis due to the particular pathophysiological condition in the elderly. It is important to encourage the habit of individ ually evaluating potential risk versus expected advantages of drugs in keeping with the same principles adopted in the evaluation of cost/benefit ratio.
Book Synopsis Drug-related problems in the elderly by : Patrik Midlöv
Download or read book Drug-related problems in the elderly written by Patrik Midlöv and published by Springer Science & Business Media. This book was released on 2009-07-07 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-related problems in the elderly is intended to serve as a source of information and clinical support in geriatric pharmacotherapy for students as well as all health care professionals, e.g. physicians, nurses and pharmacists. Pharmacotherapy is of great importance to all mankind. Drugs are however powerful and must be handled appropriately. This is especially important for elderly patients. Drug-related problem is not a major subject in most university programmes in medicine or pharmacy. When there is no speci c course, there is often no book covering the topic. In our view, as teachers at various university courses, there has been a shortage of literature that re ects the most important aspects of drug-related problems in the elderly. Medical practitioners, nurses and pharmacists, need to have this knowledge to be able to serve their patients in the best way. This book covers most aspects of drug-related problems in the elderly. With b- ter knowledge of drug-related dif culties and risks we hope that elderly will have fewer drug-related problems and bene t more from their pharmacotherapy.
Book Synopsis Patient Safety and Quality by : Ronda Hughes
Download or read book Patient Safety and Quality written by Ronda Hughes and published by Department of Health and Human Services. This book was released on 2008 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nurses play a vital role in improving the safety and quality of patient car -- not only in the hospital or ambulatory treatment facility, but also of community-based care and the care performed by family members. Nurses need know what proven techniques and interventions they can use to enhance patient outcomes. To address this need, the Agency for Healthcare Research and Quality (AHRQ), with additional funding from the Robert Wood Johnson Foundation, has prepared this comprehensive, 1,400-page, handbook for nurses on patient safety and quality -- Patient Safety and Quality: An Evidence-Based Handbook for Nurses. (AHRQ Publication No. 08-0043)." - online AHRQ blurb, http://www.ahrq.gov/qual/nurseshdbk/
Book Synopsis Anti-Aging Pharmacology by : Vitaly Koltover
Download or read book Anti-Aging Pharmacology written by Vitaly Koltover and published by Academic Press. This book was released on 2022-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world’s leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice. Includes updated information about current developments in anti-aging pharmacology Offers practical advice on the applicability of certain healthspan-promoting medications Discusses potential challenges related to the translation of anti-aging drugs in clinical practice
Book Synopsis Aging and Drug Therapy by : G. Barbagallo-Sangiorgi
Download or read book Aging and Drug Therapy written by G. Barbagallo-Sangiorgi and published by . This book was released on 2014-01-15 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Contemporary Perspectives on Ageism by : Liat Ayalon
Download or read book Contemporary Perspectives on Ageism written by Liat Ayalon and published by Springer. This book was released on 2018-05-22 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive perspective on the concept of ageism, its origins, the manifestation and consequences of ageism, as well as ways to respond to and research ageism. The book represents a collaborative effort of researchers from over 20 countries and a variety of disciplines, including, psychology, sociology, gerontology, geriatrics, pharmacology, law, geography, design, engineering, policy and media studies. The contributors have collaborated to produce a truly stimulating and educating book on ageism which brings a clear overview of the state of the art in the field. The book serves as a catalyst to generate research, policy and public interest in the field of ageism and to reconstruct the image of old age and will be of interest to researchers and students in gerontology and geriatrics.
Author :United States. Congress. House. Select Committee on Aging. Subcommittee on Human Services Publisher : ISBN 13 : Total Pages :612 pages Book Rating :4.3/5 (91 download)
Book Synopsis Drug Misuse Among the Elderly and Its Impact on Community-based Care by : United States. Congress. House. Select Committee on Aging. Subcommittee on Human Services
Download or read book Drug Misuse Among the Elderly and Its Impact on Community-based Care written by United States. Congress. House. Select Committee on Aging. Subcommittee on Human Services and published by . This book was released on 1989 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The aging process and psychoactive drug abuse by : National Institute on Drug Abuse. Services Research Branch
Download or read book The aging process and psychoactive drug abuse written by National Institute on Drug Abuse. Services Research Branch and published by . This book was released on 1979 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drugs, Ageing and Society by : Bruce Burns
Download or read book Drugs, Ageing and Society written by Bruce Burns and published by Taylor & Francis. This book was released on 2024-05-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 1970s and 1980s prescription and over-the-counter drugs had come to play a major role in the health care of older people. Originally published in 1986, this book reviews the historical background to this development and explores its social and pharmacological implications. The main aim of the study was to provide a critical perspective on drug use together with a framework for developing effective prescribing policies. The authors do not, in developing their arguments, reject the enormous value of drugs in the treatment of many illnesses affecting older people; they do, however, criticise excessive as well as inappropriate prescribing. The intention was to provide some practical illustrations of how the harmful effects of drug use can be curtailed. This book was aimed, in particular, at workers in the health services, for example: doctors, health visitors, district nurses, pharmacists, the professions allied to medicine. However, it should also be of interest to other groups such as social workers, carers, support groups and older people themselves.
Book Synopsis Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations by : Institute of Medicine
Download or read book Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations written by Institute of Medicine and published by National Academies Press. This book was released on 1997-08-25 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.
Book Synopsis Symptoms in the Pharmacy by : Alison Blenkinsopp
Download or read book Symptoms in the Pharmacy written by Alison Blenkinsopp and published by John Wiley & Sons. This book was released on 2013-03-27 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical and evidence-based guide for student, pre-registration and qualified pharmacists Symptoms in the Pharmacy is an indispensable guide to the management of common symptoms seen in the pharmacy. With advice from an author team that includes both pharmacists and GPs, the book covers ailments which will be encountered in the pharmacy on a daily basis. Now in its sixth edition Symptoms in the Pharmacy has been fully revised to reflect the latest evidence and availability of new medicines. There are new sections and case studies for 'POM' to 'P' switches including chloramphenicol, sumatriptan, diclofenac, naproxen and amorolfine. This edition features colour photographs of skin conditions for the first time enabling the differentiation and diagnosis of common complaints. The public health and illness prevention content have been expanded to support this increasingly important aspect of the pharmacist’s work. The book is designed for quick and easy reference with separate chapters for each ailment. Each chapter incorporates a decision making framework in which the information necessary for treatment and suggestions on ‘when to refer’ is distilled into helpful summary boxes. At the end of each chapter there are example case studies providing the view of pharmacists, doctors and patients for most conditions covered. These easy-to-follow- chapters can be read cover to cover or turned to for quick reference. This useful guide should be kept close at hand for frequent consultation.
Book Synopsis Drugs and the Elderly by : Helene L. Lipton
Download or read book Drugs and the Elderly written by Helene L. Lipton and published by Stanford University Press. This book was released on 1988 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Stanford University Press classic.
Book Synopsis Elderly by : United States. Congress. House. Select Committee on Aging
Download or read book Elderly written by United States. Congress. House. Select Committee on Aging and published by . This book was released on 1984 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drugs and the Elderly by : Ronald C. Kayne
Download or read book Drugs and the Elderly written by Ronald C. Kayne and published by Ethel Percy Andrus Gerontology California. This book was released on 1978 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
