Dr. Folkman's War

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Publisher :
ISBN 13 : 9780812974843
Total Pages : 0 pages
Book Rating : 4.9/5 (748 download)

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Book Synopsis Dr. Folkman's War by : Robert Cooke

Download or read book Dr. Folkman's War written by Robert Cooke and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1961, twenty-eight-year-old Dr. Judah Folkman saw something while doing medical research in a United States navy lab that gave him the first glimmering of a wild, inspired hunch. What if cancerous tumors, in order to expand, needed to trigger the growth of new blood vessels to feed themselves? And if that was true, what if a way could be found to stop that growth? Could cancers be starved to death? Dr. Folkman had ample reason to be self confident — second in his class at Harvard Medical School, he was already considered one of the most promising doctors of his generation. But even he never guessed that his idea would eventually grow into a multibillion-dollar industry that is now racing through human trials with drugs that show unparalleled promise of being able to control cancer, as well as other deadly diseases. For the creation of this book, Dr. Judah Folkman cooperated fully and exclusively with acclaimed science writer Robert Cooke. He granted Cooke unlimited interviews, showed him diaries and personal papers, and threw open the doors of his lab. The result is an astonishingly rich and candid chronicle of one of the most significant medical discoveries of our time and of the man whose vision and persistence almost single-handedly has made it possible. Dr. Folkman's radical new way of thinking about cancer was once considered preposterous. So little was known about how cancer spreads and how blood vessels grow that he wasn't even taken seriously enough to be considered a heretic. Other doctors shook their heads at the waste of a great mind, and ambitious young medical researchers were told that accepting a position in Folkman's lab would be the death of their careers. Now, though, the overwhelming majority of experts believes that the day will soon come when antiangiogenesis therapy supplants the current more toxic and less-effective treatments — chemotherapy, radiation, and surgery-as the preferred method of treatment for cancer in patients around the world, and Dr. Folkman's breakthrough will come to be taken for granted the way we now take for granted the polio vaccine and antibiotics. Dr. Folkman's War brilliantly describes how high the odds are against success in medical research, how vicious the competition for grants, how entrenched the skepticism about any genuinely original thinking, how polluted by politics and commerce the process of getting medicine into patients' hands. But it also depicts with rare power how exalted a calling medicine can be and how for the rare few—the brilliant, the tireless, and the lucky — the results of success can be world-changing. From the Hardcover edition.

Dr. Folkman's War

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Author :
Publisher : Random House Digital, Inc.
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Dr. Folkman's War by : Robert Cooke

Download or read book Dr. Folkman's War written by Robert Cooke and published by Random House Digital, Inc.. This book was released on 2001 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This electrifying, intimate account is the exclusive inside story of cancer pioneer Judah Folkman's 35-year pursuit of an idea that is revolutionizing the way cancer is treated around the world.

Dr. Folkman's War

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Author :
Publisher :
ISBN 13 : 9780756756956
Total Pages : 366 pages
Book Rating : 4.7/5 (569 download)

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Book Synopsis Dr. Folkman's War by : Robert Cooke

Download or read book Dr. Folkman's War written by Robert Cooke and published by . This book was released on 2002-07 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1961, twenty-eight-year-old Dr. Judah Folkman saw something while doing medical research in a United States navy lab that gave him the first glimmering of a wild, inspired hunch. What if cancerous tumors, in order to expand, needed to trigger the growth of new blood vessels to feed themselves? And if that was true, what if a way could be found to stop that growth? Could cancers be starved to death? Dr. Folkman had ample reason to be self confident second in his class at Harvard Medical School, he was already considered one of the most promising doctors of his generation. But even he never guessed that his idea would eventually grow into a multibillion-dollar industry that is now racing through human trials with drugs that show unparalleled promise of being able to control cancer, as well as other deadly diseases. For the creation of this book, Dr. Judah Folkman cooperated fully and exclusively with acclaimed science writer Robert Cooke. He granted Cooke unlimited interviews, showed him diaries and personal papers, and threw open the doors of his lab. The result is an astonishingly rich and candid chronicle of one of the most significant medical discoveries of our time and of the man whose vision and persistence almost single-handedly has made it possible. Dr. Folkman's radical new way of thinking about cancer was once considered preposterous. So little was known about how cancer spreads and how blood vessels grow that he wasn't even taken seriously enough to be considered a heretic. Other doctors shook their heads at the waste of a great mind, and ambitious young medical researchers were told that accepting a position in Folkman's lab would be the death of their careers. Now, though, the overwhelming majority of experts believes that the day will soon come when antiangiogenesis therapy supplants the current more toxic and less-effective treatments chemotherapy, radiation, and surgery-as the preferred method of treatment for cancer in patients around the world, and Dr. Folkman's breakthrough will come to be taken for granted the way we now take for granted the polio vaccine and antibiotics. Dr. Folkman's War brilliantly describes how high the odds are against success in medical research, how vicious the competition for grants, how entrenched the skepticism about any genuinely original thinking, how polluted by politics and commerce the process of getting medicine into patients' hands. But it also depicts with rare power how exalted a calling medicine can be and how for the rare fewthe brilliant, the tireless, and the lucky the results of success can be world-changing. From the Hardcover edition.

Dr. Folkman's War

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Author :
Publisher : Century
ISBN 13 : 9780712676762
Total Pages : 448 pages
Book Rating : 4.6/5 (767 download)

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Book Synopsis Dr. Folkman's War by : Robert Cooke

Download or read book Dr. Folkman's War written by Robert Cooke and published by Century. This book was released on 2001 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1998, Nobel laureate Dr James Watson, co-discoverer of the structure of DNA, said that, in time, Doctor Judah Folkman would be considered the twentieth century's Darwin for his pioneering research into a cure for cancer. However, at that time, although medicines emerging from Folkman's library were curing many forms of cancer, completely and without side effects, success was only seen in mice. Doing the same in humans seemed a long time away.Now that time seems near. Dr Folkman's theory of anti-angiogenesis - that cancer cells can be starved by cutting off their blood supply - has gone into fast-track clinical trials. The new agents rank among the most important new weapons in the war against cancer to emerge in our time. Already, scores of patients thought doomed have had their cancers cured.Doctor Folkman's War is the chronicle of an epoch-making scientific achievement and the story of a man who turned his back on a golden career in surgery to embark on a lonely and lifelong pursuit of a challenging idea. It was an idea roundly ridiculed and dismissed as ludicrous, but it could turn the tide against cancer and have an impact on several dozen other stubborn ailments - soon. Science journalist Robert Cooke is the only writer who has been given complete and exclusive access to Judah Folkman and his staff, and he is also following patients taking part in clinical trials.

Breast Cancer Basics and Beyond

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Publisher : Hunter House
ISBN 13 : 9780897934541
Total Pages : 388 pages
Book Rating : 4.9/5 (345 download)

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Book Synopsis Breast Cancer Basics and Beyond by : Delthia Ricks

Download or read book Breast Cancer Basics and Beyond written by Delthia Ricks and published by Hunter House. This book was released on 2005 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Having breast cancer can be devastating for the woman affected - and for her family and loved ones. It can also be confusing, because there are many variations of the disease and at least as many treatments. By bringing together comprehensive information on the subject, Breast Cancer Basics and Beyond helps women better understand their illness and participate in making decisions about all aspects of their treatment and care. In this book, award-winning medical writer Delthia Ricks tells you all about: common and rare types of breast cancer, their causes and symptoms, diagnosis, including mammography and different kinds of biopsies, treatment options, including lumpectomy, mastectomy, chemotherapy, radiation and hormone therapy, benefits and side effects of the most commonly used drugs, your risk factors, including ethnicity, genetics, hormones and diet, life after cancer, follow-up care and dealing with recurrence, reasons for hope: breast cancer research and treatments in development.

Angiogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 0387715185
Total Pages : 592 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Angiogenesis by : William D. Figg

Download or read book Angiogenesis written by William D. Figg and published by Springer Science & Business Media. This book was released on 2008-05-24 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Judah Folkman is considered the "father of angiogenesis." Because of Folkman's discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. Angiogenesis: An Integrative Approach from Science to Medicine is a comprehensive, concise summary of tumor angiogenesis. It is an up-to-date and authoritative reference for the angiogenesis field as it relates to oncology. This book represents the first collection in a volume of which Folkman is co-editor. Folkman has authored nearly 400 original papers and more than 100 book chapters.

Saving Sight

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Publisher : Irie Books
ISBN 13 : 9781515438953
Total Pages : 232 pages
Book Rating : 4.4/5 (389 download)

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Book Synopsis Saving Sight by : Andrew Lam

Download or read book Saving Sight written by Andrew Lam and published by Irie Books. This book was released on 2013-05-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Saving Sight, Dr. Andrew Lam explains the intricacies of human sight and shines a light on the heroes who fought to save it, while also revealing the personal side of life as an eye surgeon - the stress and joy of a man who, on his best days, can turn darkness into light. Many remarkable life stories illuminate this autobiographical/biographical/historical work. Included are Louis Braille, Judah Folkman, Harold Ridley and many others who have enabled us to see in all kinds of unimaginable ways.

The Emperor of All Maladies

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Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee

Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

War Tourism

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Publisher :
ISBN 13 : 9781501715877
Total Pages : 0 pages
Book Rating : 4.7/5 (158 download)

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Book Synopsis War Tourism by : Bertram M. Gordon

Download or read book War Tourism written by Bertram M. Gordon and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book addresses the linkages between tourism and war, focusing on tourism by German personnel and French civilians during the Second World War and on postwar memory tourism"--

The Spirit Catches You and You Fall Down

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Publisher : Macmillan
ISBN 13 : 0374533407
Total Pages : 370 pages
Book Rating : 4.3/5 (745 download)

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Book Synopsis The Spirit Catches You and You Fall Down by : Anne Fadiman

Download or read book The Spirit Catches You and You Fall Down written by Anne Fadiman and published by Macmillan. This book was released on 2012-04-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the National Book Critics Circle Award for Nonfiction, this brilliantly reported and beautifully crafted book explores the clash between a medical center in California and a Laotian refugee family over their care of a child.

Happy Accidents

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Publisher : Skyhorse Publishing Inc.
ISBN 13 : 1611451620
Total Pages : 115 pages
Book Rating : 4.6/5 (114 download)

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Book Synopsis Happy Accidents by : Morton A. Meyers

Download or read book Happy Accidents written by Morton A. Meyers and published by Skyhorse Publishing Inc.. This book was released on 2011-09 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the twentieth century.

Loonshots

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Publisher : St. Martin's Press
ISBN 13 : 1250185971
Total Pages : 304 pages
Book Rating : 4.2/5 (51 download)

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Book Synopsis Loonshots by : Safi Bahcall

Download or read book Loonshots written by Safi Bahcall and published by St. Martin's Press. This book was released on 2019-03-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Instant WSJ bestseller * Translated into 18 languages * #1 Most Recommended Book of the year (Bloomberg annual survey of CEOs and entrepreneurs) * An Amazon, Bloomberg, Financial Times, Forbes, Inc., Newsweek, Strategy + Business, Tech Crunch, Washington Post Best Business Book of the year * Recommended by Bill Gates, Daniel Kahneman, Malcolm Gladwell, Dan Pink, Adam Grant, Susan Cain, Sid Mukherjee, Tim Ferriss Why do good teams kill great ideas? Loonshots reveals a surprising new way of thinking about the mysteries of group behavior that challenges everything we thought we knew about nurturing radical breakthroughs. Bahcall, a physicist and entrepreneur, shows why teams, companies, or any group with a mission will suddenly change from embracing new ideas to rejecting them, just as flowing water will suddenly change into brittle ice. Mountains of print have been written about culture. Loonshots identifies the small shifts in structure that control this transition, the same way that temperature controls the change from water to ice. Using examples that range from the spread of fires in forests to the hunt for terrorists online, and stories of thieves and geniuses and kings, Bahcall shows how a new kind of science can help us become the initiators, rather than the victims, of innovative surprise. Over the past decade, researchers have been applying the tools and techniques of this new science—the science of phase transitions—to understand how birds flock, fish swim, brains work, people vote, diseases erupt, and ecosystems collapse. Loonshots is the first to apply this science to the spread of breakthrough ideas. Bahcall distills these insights into practical lessons creatives, entrepreneurs, and visionaries can use to change our world. Along the way, readers will learn how chickens saved millions of lives, what James Bond and Lipitor have in common, what the movie Imitation Game got wrong about WWII, and what really killed Pan Am, Polaroid, and the Qing Dynasty. “If The Da Vinci Code and Freakonomics had a child together, it would be called Loonshots.” —Senator Bob Kerrey

Rebound

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Publisher : Rowman & Littlefield
ISBN 13 : 1442223812
Total Pages : 266 pages
Book Rating : 4.4/5 (422 download)

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Book Synopsis Rebound by : Kim R. Holmes

Download or read book Rebound written by Kim R. Holmes and published by Rowman & Littlefield. This book was released on 2013-11-07 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a huge concern in America today that the country is in decline, one of the few sentiments that – nationally – our increasingly polarized political leaders can agree on. Americans fear that the economy and our culture itself are in deep crisis. They are also frustrated that the ruling classes are unable to fix America’s problems. Kim R. Holmes’ Rebound taps into these concerns, taking a fresh look at how America has moved away from the principles and practices that once made it the world’s greatest nation. Far from accepting America’s inevitable decline, as so many today do, Holmes argues that decline is a choice, not an inevitability or destiny. To restore our culture, revitalize our economy, and ensure we return to being the world’s number one power, America must reconnect with its historical DNA: the ingredients of its greatness. This book lays out the vision and roadmap for how America can bounce back, with examples from throughout our nation’s history that prove we’ve always been able to meet the challenges facing us, no matter how largely they may loom.

Indispensable

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Publisher : Harvard Business Press
ISBN 13 : 1422186717
Total Pages : 318 pages
Book Rating : 4.4/5 (221 download)

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Book Synopsis Indispensable by : Gautam Mukunda

Download or read book Indispensable written by Gautam Mukunda and published by Harvard Business Press. This book was released on 2012-08-14 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Will your next leader be insignificant—or indispensable? The importance of leadership and the impact of individual leaders has long been the subject of debate. Are they made by history, or do they make it? In Indispensable, Harvard Business School professor Gautam Mukunda offers an enticingly fresh look at how and when individual leaders really can make a difference. By identifying and analyzing the hidden patterns of their careers, and by exploring the systems that place these leaders in positions of power, Indispensable sheds new light on how we may be able to identify the best leaders and what lessons we can learn, from both the process and the result. Profiling a mix of historic and modern figures—from Thomas Jefferson and Abraham Lincoln to Winston Churchill and Judah Folkman—and telling the stories of how they came to power and how they made the most important decisions of their lives, Indispensable reveals how, when, and where a single individual in the right place at the right time can save or destroy the organization they lead, and even change the course of history. Indispensable will also help you understand this new model so you can use it in your own life—whether you’re a citizen casting a ballot, an executive choosing your next CEO, or a leader trying to make your mark.

Eat to Beat Disease

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Author :
Publisher : Balance
ISBN 13 : 1538714639
Total Pages : 371 pages
Book Rating : 4.5/5 (387 download)

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Book Synopsis Eat to Beat Disease by : William W Li

Download or read book Eat to Beat Disease written by William W Li and published by Balance. This book was released on 2019-03-19 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eat your way to better health with this New York Times bestseller on food's ability to help the body heal itself from cancer, dementia, and dozens of other avoidable diseases. Forget everything you think you know about your body and food, and discover the new science of how the body heals itself. Learn how to identify the strategies and dosages for using food to transform your resilience and health in Eat to Beat Disease. We have radically underestimated our body's power to transform and restore our health. Pioneering physician scientist, Dr. William Li, empowers readers by showing them the evidence behind over 200 health-boosting foods that can starve cancer, reduce your risk of dementia, and beat dozens of avoidable diseases. Eat to Beat Disease isn't about what foods to avoid, but rather is a life-changing guide to the hundreds of healing foods to add to your meals that support the body's defense systems, including: Plums Cinnamon Jasmine tea Red wine and beer Black Beans San Marzano tomatoes Olive oil Pacific oysters Cheeses like Jarlsberg, Camembert and cheddar Sourdough bread The book's plan shows you how to integrate the foods you already love into any diet or health plan to activate your body's health defense systems-Angiogenesis, Regeneration, Microbiome, DNA Protection, and Immunity-to fight cancer, diabetes, cardiovascular, neurodegenerative autoimmune diseases, and other debilitating conditions. Both informative and practical, Eat to Beat Disease explains the science of healing and prevention, the strategies for using food to actively transform health, and points the science of wellbeing and disease prevention in an exhilarating new direction.

Tumour Angiogenesis

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Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Tumour Angiogenesis by : R. John Bicknell

Download or read book Tumour Angiogenesis written by R. John Bicknell and published by . This book was released on 1997 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumour Angiogenesis is the first comprehensive book to cover all areas of this rapidly expanding research area. Each chapter is written by world experts in the field and topics covered include in vivo models, mechanisms, inhibition, and the role of macrophages, cytokines, proteases,extracellular matrix components, nitric oxide, prostanoids and oncogenes/tumour suppressor genes in angiogenesis. Other chapters examine the role of specific growth factors in angiogenesis - these include vascular endothelial growth factor, the basic fibroblast growth factor family, transforminggrowth factor-beta, tumour necrosis factor-alpha, platelet-derived endothelial cell growth factor/thymidine phosphorylase and pleiotrophin and related molecules. Clinical issues are addressed in chapters that deal with the prognostic and predictive value of tumour microvessel density and thetherapeutic significance of microregional blood flow. The two final chapters examine the feasibility of targeting tumour vasculature using either antibodies or gene therapy.

Gynecologic Radiation Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3540689583
Total Pages : 301 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Gynecologic Radiation Therapy by : Akila N. Viswanathan

Download or read book Gynecologic Radiation Therapy written by Akila N. Viswanathan and published by Springer Science & Business Media. This book was released on 2010-10-17 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the treatment of gynecologic malignancies led to a new worldwide consensus to introduce image guidance to gynecologic radiation therapy, particularly to brachytherapy. The book summarizes the changed practice of management: treatment planning for cervical cancer, not modified for over 60 years, has been shifted to an image-based approach, endometrial cancer management with an increase in the use of chemotherapy and vaginal brachytherapy, and vaginal cancer therapy including image guidance and high-dose delivery with IMRT.