Downstream Processing In Biotechnology Recovery And Purification Of Bioproducts And Recovery Of Bioproducts

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Engineering Principles in Biotechnology

Author : Wei-Shou Hu
Publisher : John Wiley & Sons
ISBN 13 : 1119159024
Total Pages : 502 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Engineering Principles in Biotechnology by : Wei-Shou Hu

Download or read book Engineering Principles in Biotechnology written by Wei-Shou Hu and published by John Wiley & Sons. This book was released on 2017-11-13 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.

Downstream Processing in Biotechnology

Author : Venko N. Beschkov
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 311057411X
Total Pages : 177 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Downstream Processing in Biotechnology by : Venko N. Beschkov

Download or read book Downstream Processing in Biotechnology written by Venko N. Beschkov and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-06-21 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book gives an excellent insight into downstream processing technology and explains how to establish a successful strategy for an efficient recovery, isolation and purification of biosynthetic products. In addition to the overview of purification steps and unit operations, the authors provide practical information on capital and operating costs related to downstream processing.

UPSTREAM AND DOWNSTREAM PROCESSING OF BIOPRODUCTS

Author : R. Puvanakrishnan
Publisher : MJP Publisher
ISBN 13 :
Total Pages : 242 pages
Book Rating : 4./5 ( download)

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Book Synopsis UPSTREAM AND DOWNSTREAM PROCESSING OF BIOPRODUCTS by : R. Puvanakrishnan

Download or read book UPSTREAM AND DOWNSTREAM PROCESSING OF BIOPRODUCTS written by R. Puvanakrishnan and published by MJP Publisher. This book was released on 2019-06-20 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microorganisms have been exploited for many centuries for the production of fermented foods and beverages and for bread-making. The production of alcoholic beverages using microbes was the first major industrialized process. The technology developed for large-scale brewing was adapted for other anaerobic processes such as acetone and butanol in the early 1900s. With the discovery of penicillins, rapid developments were made in the technology of submerged culture fermentation of aerobic microorganisms under controlled conditions. The advancements in microbiology and process biochemistry improved our ability to harness the potential of microorganisms through improved bioprocessing methods to manufacture new products with economic viability. Microbial derived bioproducts have been gaining importance in the food, pharmaceutical, textile, leather, cosmetic and chemical industries, and most important among them are therapeutic proteins and peptides, enzymes, antigens, vaccines, antibiotics, drugs, etc.Not all microbial production processes involve culture of the organism in liquid medium. Instead, the organism can be grown on the surface of a solid substrate. Solid substrate (or solid state) fermentation (SSF) is an established traditional technology in many countries, producing edible mushrooms, fungal- fermented foods and soy sauce. Before the development of processes in liquid culture, citric acid and some microbial enzymes were produced by SSF. Carbon composting is also a form of SSF.

Downstream Process Technology: A New Horizon In Biotechnology

Author : Krishna Kant Prasad
Publisher : PHI Learning Pvt. Ltd.
ISBN 13 : 812034040X
Total Pages : 374 pages
Book Rating : 4.1/5 (23 download)

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Book Synopsis Downstream Process Technology: A New Horizon In Biotechnology by : Krishna Kant Prasad

Download or read book Downstream Process Technology: A New Horizon In Biotechnology written by Krishna Kant Prasad and published by PHI Learning Pvt. Ltd.. This book was released on 2010-01-30 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, biochemical process industry demands fast and economic processes for the partitioning and purification of biomolecules that give high yield and high purity of the product. An integral and cost intensive part of these processes is associated with downstream processing for product isolation and purification. The aim of this comprehensive text is to provide an insightful overview of the whole aspects of downstream processing for biochemical product recovery. Intended for undergraduate and postgraduate students of biotechnology and chemical engineering, this self-contained text includes the chapters based on the recent developments in the industry and academics. It covers the importance of the downstream processing in terms of its relevancy to modern days ever-changing consumer needs, process design criteria relevance to set objectives, and physicochemical factors that help to formulate the strategy to develop a configuration among the raw material, methodology and instruments. This overview is followed by different downstream processing steps. The text concludes with the discussion on stabilization of the product to improve the shelf life of the product. Key Features Includes detailed biological, mathematical, chemical and physical aspects of downstream processing. Distinguishes downstream processing from analytical bioseparation. Contains numerous illustrations and solved problems.

Principles Of Bioseparations Engineering

Author : Raja Ghosh
Publisher : World Scientific Publishing Company
ISBN 13 : 981310676X
Total Pages : 282 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Principles Of Bioseparations Engineering by : Raja Ghosh

Download or read book Principles Of Bioseparations Engineering written by Raja Ghosh and published by World Scientific Publishing Company. This book was released on 2006-10-23 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students.

Bioseparations Science and Engineering

Author : Roger G. Harrison
Publisher : Oxford University Press
ISBN 13 : 0190213736
Total Pages : 577 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Bioseparations Science and Engineering by : Roger G. Harrison

Download or read book Bioseparations Science and Engineering written by Roger G. Harrison and published by Oxford University Press. This book was released on 2015-01-27 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.

Introduction to Biomanufacturing

Author : Northeast Biomanufacturing Center & Collaborative
Publisher :
ISBN 13 : 9781939070012
Total Pages : 510 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Introduction to Biomanufacturing by : Northeast Biomanufacturing Center & Collaborative

Download or read book Introduction to Biomanufacturing written by Northeast Biomanufacturing Center & Collaborative and published by . This book was released on 2012-11-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today is a time of unparalleled excitement in the world of biopharmaceuticals. This book is a compendium of a tremendous body of knowledge, distilled into its most essential parts. Not only are there theoretical and conceptual ideas about biopharmaceutical manufacturing, but also content specific to skills and abilities. It serves as a well-paced guide for beginning learners as well as a cogent reference for seasoned biotechnology professionals alike. This book will help a new generation of students to become inspired and familiarize themselves with the theories, principles, and vernacular of biopharmaceutical production and all that it entails. A quick overview of contents include; Operational Excellence, Facilities, Metrology, Validation, Environmental Health & Safety (EHS), Quality Assurance, Microbiological Control, Quality Control Biochemistry, Upstream Processing, Downstream Processing, Process Development, and a Master Glossary.

Separation and Purification Technologies in Biorefineries

Author : Shri Ramaswamy
Publisher : John Wiley & Sons
ISBN 13 : 111849346X
Total Pages : 730 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Separation and Purification Technologies in Biorefineries by : Shri Ramaswamy

Download or read book Separation and Purification Technologies in Biorefineries written by Shri Ramaswamy and published by John Wiley & Sons. This book was released on 2013-02-04 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Separation and purification processes play a critical role in biorefineries and their optimal selection, design and operation to maximise product yields and improve overall process efficiency. Separations and purifications are necessary for upstream processes as well as in maximising and improving product recovery in downstream processes. These processes account for a significant fraction of the total capital and operating costs and also are highly energy intensive. Consequently, a better understanding of separation and purification processes, current and possible alternative and novel advanced methods is essential for achieving the overall techno-economic feasibility and commercial success of sustainable biorefineries. This book presents a comprehensive overview focused specifically on the present state, future challenges and opportunities for separation and purification methods and technologies in biorefineries. Topics covered include: Equilibrium Separations: Distillation, liquid-liquid extraction and supercritical fluid extraction. Affinity-Based Separations: Adsorption, ion exchange, and simulated moving bed technologies. Membrane Based Separations: Microfiltration, ultrafiltration and diafiltration, nanofiltration, membrane pervaporation, and membrane distillation. Solid-liquid Separations: Conventional filtration and solid-liquid extraction. Hybrid/Integrated Reaction-Separation Systems: Membrane bioreactors, extractive fermentation, reactive distillation and reactive absorption. For each of these processes, the fundamental principles and design aspects are presented, followed by a detailed discussion and specific examples of applications in biorefineries. Each chapter also considers the market needs, industrial challenges, future opportunities, and economic importance of the separation and purification methods. The book concludes with a series of detailed case studies including cellulosic bioethanol production, extraction of algae oil from microalgae, and production of biopolymers. Separation and Purification Technologies in Biorefineries is an essential resource for scientists and engineers, as well as researchers and academics working in the broader conventional and emerging bio-based products industry, including biomaterials, biochemicals, biofuels and bioenergy.

Liquid Biphasic System

Author : Pau Loke Show
Publisher : Elsevier
ISBN 13 : 0128223987
Total Pages : 330 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Liquid Biphasic System by : Pau Loke Show

Download or read book Liquid Biphasic System written by Pau Loke Show and published by Elsevier. This book was released on 2020-11-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Downstream bioprocesses have a significant role to play in the creation of a sustainable bio-based economy, enabling the creation of new products and systems from the more sustainable bioprocessing of natural products. Liquid Biphasic System: Fundamentals, Methods, and Applications in Bioseparation Technology explores in detail the fundamental processes and applications of this new separation system, aiding understanding of the basic principles of the technique and offering constructive criticisms on the latest findings.Including coverage of the background, principles, mechanisms, and applications, Liquid Biphasic System addresses how to adapt the technology for the purification of useful compounds with greater cost efficiency and greener processing. It is essential reading for bioprocess engineers, biochemical engineers, biosystem engineers, chemists and microbiologists working in the fields of bioprocessing. Researchers, scientists, and engineers concerned with the selection and evaluation of alternative bioseparation processes will find the book particularly useful. - Provides information and examples of advanced separations in a single source - Includes detailed descriptions of novel bioseparation systems - Covers the latest technologies related to advanced liquid–liquid separation and their applications in various industries

Biochemical Engineering and Biotechnology

Author : Ghasem Najafpour
Publisher : Elsevier
ISBN 13 : 0444633774
Total Pages : 669 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Biochemical Engineering and Biotechnology by : Ghasem Najafpour

Download or read book Biochemical Engineering and Biotechnology written by Ghasem Najafpour and published by Elsevier. This book was released on 2015-02-24 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Engineering and Biotechnology, 2nd Edition, outlines the principles of biochemical processes and explains their use in the manufacturing of every day products. The author uses a diirect approach that should be very useful for students in following the concepts and practical applications. This book is unique in having many solved problems, case studies, examples and demonstrations of detailed experiments, with simple design equations and required calculations. - Covers major concepts of biochemical engineering and biotechnology, including applications in bioprocesses, fermentation technologies, enzymatic processes, and membrane separations, amongst others - Accessible to chemical engineering students who need to both learn, and apply, biological knowledge in engineering principals - Includes solved problems, examples, and demonstrations of detailed experiments with simple design equations and all required calculations - Offers many graphs that present actual experimental data, figures, and tables, along with explanations

Downstream Processing in Biotechnology

Author : Venko N. Beschkov
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110574004
Total Pages : 211 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Downstream Processing in Biotechnology by : Venko N. Beschkov

Download or read book Downstream Processing in Biotechnology written by Venko N. Beschkov and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-06-21 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book gives an excellent insight into downstream processing technology and explains how to establish a successful strategy for an efficient recovery, isolation and purification of biosynthetic products. In addition to the overview of purification steps and unit operations, the authors provide practical information on capital and operating costs related to downstream processing.

Bioseparation

Author : G.T. Tsao
Publisher : Springer
ISBN 13 : 9783662149881
Total Pages : 200 pages
Book Rating : 4.1/5 (498 download)

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Book Synopsis Bioseparation by : G.T. Tsao

Download or read book Bioseparation written by G.T. Tsao and published by Springer. This book was released on 2014-03-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts

Author : Claire Komives
Publisher : John Wiley & Sons
ISBN 13 : 1118361989
Total Pages : 288 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts by : Claire Komives

Download or read book Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts written by Claire Komives and published by John Wiley & Sons. This book was released on 2018-12-27 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: • Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries • Includes illustrative case studies that review six milestone bio-products • Discuses a wide selection of host strain types and disruptive bioprocess technologies

Biomass and Biofuels from Microalgae

Author : Navid R. Moheimani
Publisher : Springer
ISBN 13 : 3319166409
Total Pages : 373 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Biomass and Biofuels from Microalgae by : Navid R. Moheimani

Download or read book Biomass and Biofuels from Microalgae written by Navid R. Moheimani and published by Springer. This book was released on 2015-04-11 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book details the most recent advances in the microalgae biological sciences and engineering technologies for biomass and biofuel production in order to meet the ongoing need for new and affordable sources of food, chemicals and energy for future generations. The chapters explore new microalgae cultivation techniques, including solid (biofilm) systems, and heterotrophic production methods, while also critically investigating topics such as combining wastewater as a source of nutrients, the effect of CO2 on growth, and converting biomass to methane through anaerobic digestion. The book highlights innovative bioproduct optimization and molecular genetic techniques, applications of genomics and metabolomics, and the genetic engineering of microalgae strains targeting biocrude production. The latest developments in microalgae harvesting and dewatering technologies, which combine biomass production with electricity generation, are presented, along with detailed techno-economic modeling. This extensive volume was written by respected experts in their fields and is intended for a wide audience of researchers and engineers.

Bioprocess Engineering

Author : Kim Gail Clarke
Publisher : Elsevier
ISBN 13 : 1782421688
Total Pages : 266 pages
Book Rating : 4.7/5 (824 download)

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Book Synopsis Bioprocess Engineering by : Kim Gail Clarke

Download or read book Bioprocess Engineering written by Kim Gail Clarke and published by Elsevier. This book was released on 2013-10-31 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology is an expansive field incorporating expertise in both the life science and engineering disciplines. In biotechnology, the scientist is concerned with developing the most favourable biocatalysts, while the engineer is directed towards process performance, defining conditions and strategies that will maximize the production potential of the biocatalyst. Increasingly, the synergistic effect of the contributions of engineering and life sciences is recognised as key to the translation of new bioproducts from the laboratory bench to commercial bioprocess. Fundamental to the successful realization of the bioprocess is a need for process engineers and life scientists competent in evaluating biological systems from a cross-disciplinary viewpoint. Bioprocess engineering aims to generate core competencies through an understanding of the complementary biotechnology disciplines and their interdependence, and an appreciation of the challenges associated with the application of engineering principles in a life science context. Initial chapters focus on the microbiology, biochemistry and molecular biology that underpin biocatalyst potential for product accumulation. The following chapters develop kinetic and mass transfer principles that quantify optimum process performance and scale up. The text is wide in scope, relating to bioprocesses using bacterial, fungal and enzymic biocatalysts, batch, fed-batch and continuous strategies and free and immobilised configurations. - Details the application of chemical engineering principles for the development, design, operation and scale up of bioprocesses - Details the knowledge in microbiology, biochemistry and molecular biology relevant to bioprocess design, operation and scale up - Discusses the significance of these life sciences in defining optimum bioprocess performance

Bioprocess Engineering

Author : Pau Loke Show
Publisher : CRC Press
ISBN 13 : 0429882521
Total Pages : 233 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Bioprocess Engineering by : Pau Loke Show

Download or read book Bioprocess Engineering written by Pau Loke Show and published by CRC Press. This book was released on 2019-05-24 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

Continuous Biomanufacturing

Author : Ganapathy Subramanian
Publisher : John Wiley & Sons
ISBN 13 : 3527340637
Total Pages : 628 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Continuous Biomanufacturing by : Ganapathy Subramanian

Download or read book Continuous Biomanufacturing written by Ganapathy Subramanian and published by John Wiley & Sons. This book was released on 2017-12-26 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.