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Author : Jørgen Scheel-Krüger
Publisher :
ISBN 13 :
Total Pages : 484 pages
Book Rating : 4.:/5 (318 download)
Download or read book Dopamine-GABA Interactions written by Jørgen Scheel-Krüger and published by . This book was released on 1986 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Scheel-Krüger
Publisher :
ISBN 13 :
Total Pages : 54 pages
Book Rating : 4.:/5 (421 download)
Download or read book Dopamine-Gaba Interactions written by J. Scheel-Krüger and published by . This book was released on 1986 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Antonius M. VanDongen
Publisher : CRC Press
ISBN 13 : 142004415X
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)
Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written
Author : Susan Jones
Publisher : CRC Press
ISBN 13 : 1420088807
Total Pages : 282 pages
Book Rating : 4.4/5 (2 download)
Download or read book Dopamine - Glutamate Interactions in the Basal Ganglia written by Susan Jones and published by CRC Press. This book was released on 2016-04-19 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basal ganglia are involved in complex brain functions, from voluntary movement control to learning and reward processing, and they are implicated in numerous neurological and psychiatric disorders. Information from the cerebral cortex and thalamus is conveyed to basal ganglia nuclei via glutamate release, while dopamine from the midbrain is rel
Author : Yoshimi Misu
Publisher : CRC Press
ISBN 13 : 1420023322
Total Pages : 404 pages
Book Rating : 4.4/5 (2 download)
Download or read book Neurobiology of DOPA as a Neurotransmitter written by Yoshimi Misu and published by CRC Press. This book was released on 2005-11-01 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: New research suggests it is highly probable that DOPA, in addition to being a precursor to dopamine, functions by itself as a neurotramsmitter and/or neuromodulator. Neurobiology of DOPA as a Neurotransmitter integrates background information about DOPA as an inert amino acid precursor of dopamine with the evidence showing that DOPA fulfills several criteria of neurotransmitters. Providing easy access to, and complete understanding of, the latest research on the subject, the book makes the case that DOPA meets many of the criteria of neurotransmitters and includes anti-evidence in some instances. The book begins with a historical review of current knowledge of DOPA. It characterizes DOPA as a prominent example showing transmutation from an inert substance to a gold drug in Parkinson's disease and further to a neurotransmitter in its own right. The next chapters cover the essential criteria of a neurotransmitter such as synthesis, existence, and competitive antagonism. The book describes metabolism composed of catecholamine synthesis and degradation products related to neuron death, physiological release of DOPA in the lower brainstem, striatum, and nucleus accumbens, and physiological or pharmacological responses involved in baroreflex neurotransmission and related to behavioral science including interactions with catecholamines, acetylcholine, glutamate, and GABA. The book explores recognition sites, transport sites, and therapeutic role and mechanisms for neuron death related to adverse influence in the treatment of Parkinson's Disease. Edited by experts in the field, the breadth and depth of information contained in this book is confirmed by a quick scan of the chapter authors. They summarize the issues surrounding DOPA neurotoxicity and explore the link between experimental studies and clinical relevance.
Author : David Nutt
Publisher : Oxford University Press, USA
ISBN 13 : 0199685703
Total Pages : 102 pages
Book Rating : 4.1/5 (996 download)
Download or read book Addiction written by David Nutt and published by Oxford University Press, USA. This book was released on 2013-09-26 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for psychiatrists, clinical psychologists, trainees, and specialist nurses, as well as primary care physicians/GPs with a special interest in mental health conditions and other healthcare professionals.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309212219
Total Pages : 74 pages
Book Rating : 4.3/5 (92 download)
Download or read book Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-05 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.
Author : Seppo Kaakkola
Publisher :
ISBN 13 : 9789519931661
Total Pages : 34 pages
Book Rating : 4.9/5 (316 download)
Download or read book Interaction of Dopamine with Acetylcholine, GABA and Opiates in Rat Brain written by Seppo Kaakkola and published by . This book was released on 1981 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author : Arne Schousboe
Publisher : Springer
ISBN 13 : 3319450964
Total Pages : 420 pages
Book Rating : 4.3/5 (194 download)
Download or read book The Glutamate/GABA-Glutamine Cycle written by Arne Schousboe and published by Springer. This book was released on 2016-11-25 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book. A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.
Author : Charles R. Ashby, Jr.
Publisher : CRC Press
ISBN 13 : 9780849347801
Total Pages : 244 pages
Book Rating : 4.3/5 (478 download)
Download or read book The Modulation of Dopaminergic Neurotransmission by Other Neurotransmitters written by Charles R. Ashby, Jr. and published by CRC Press. This book was released on 1995-12-20 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents information from different scientific disciplines - behavioral, biochemical, electrophysiological, anatomical, and medical - to detail the interaction of the neurotransmitter dopamine (DA) with other neurotransmitters or neuromodulators in the brain. Internationally recognized experts discuss the interaction of DA with monoaminergic transmitters such as norepinephrine, GABA, acetylcholine, and serotonin, as well as neuropeptide neurotransmitters/neuromodulators such as neurotensin, cholecystokinin, and the opioid peptides. This is also the first book to include data from positron emission tomography (PET) studies examining the interaction of neurotransmitters in the brain.
Author : Brian Bernard Carlson
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (471 download)
Download or read book Neurochemical Interactions in the Basal Ganglia written by Brian Bernard Carlson and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Federico Bermudez-Rattoni
Publisher : CRC Press
ISBN 13 : 1420008412
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)
Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Download or read book Effect of GABARAP (GABAʹA-receptor-associated Protein) on the Interaction Between the Dopamine DŒ5 and GABAʹA Receptors written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309082587
Total Pages : 172 pages
Book Rating : 4.3/5 (9 download)
Download or read book Caffeine for the Sustainment of Mental Task Performance written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Author : I. K. Ho
Publisher :
ISBN 13 :
Total Pages : 91 pages
Book Rating : 4.:/5 (227 download)
Download or read book Basal Ganglia Dopamine-gamma-Aminobutyric Acid-Acetylcholine Interaction in Organophosphate-Induced Neurotoxicity. Appendices written by I. K. Ho and published by . This book was released on 1982 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report contains the Appendices to the First Annual report on Basal Ganglia Dopamine-Gamma-Aminobutyric Acid-Acetylcholine Interaction in Organophosphate Induced Neurotoxicity. The appendices include information in reference to the following: Variation of Commercial Diisopropyl Fluorophosphate Preparations in Toxicological Studies; Assessment of Diisopropyl-Fluorophosphate (DFP) Toxicity; The Effect of Acute and Chronic Cholinesterase Inhibition with Diisopropylfluorophosphate On Muscarinic, Dopamine and GABA Receptors of the Rat Striatum; Diisopropylfluorophosphate and GABA Synaptic Function: Effect on Levels, Enzymes, Release and Uptake in the Rat Striatum.
Author : Gaetano Di Chiara
Publisher : Springer Science & Business Media
ISBN 13 : 9783540427209
Total Pages : 558 pages
Book Rating : 4.4/5 (272 download)
Download or read book Dopamine in the CNS II written by Gaetano Di Chiara and published by Springer Science & Business Media. This book was released on 2002-06-27 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
