Handbook of Genetics

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Publisher : Springer Science & Business Media
ISBN 13 : 1461571480
Total Pages : 662 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Handbook of Genetics by : Robert King

Download or read book Handbook of Genetics written by Robert King and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages and shortcomings of some of these revolutionary tech niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func tioning of the molecules bearing genetic information which reside in the nucleus and with the processing of this information by the ribosomes resid ing in the cytoplasm of eukaryotic cells. The mitochondria, which also live in the cytoplasm of the cells of all eukaryotes, now appear to be separate little creatures. These, as Lynn Margulis pointed out in Volume 1, are the colonial posterity of migrant prokaryotes, probably primitive bacteria that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. They have maintained themselves and their ways ever since, replicating their own DNA and transcribing an RNA quite different from that of their hosts. In a similar manner, the chloroplasts in all plants are self-replicating organelles presumably derived from the blue-green algae, with their own nucleic acids and ribosomes. Four chapters are devoted to the nucleic acids and the ribosomal components of both classes of these semi-independent lodgers. Finally, data from various sources on genetic variants of enzymes are tabulated for ready reference, and an evaluation of this information is attempted.

Cell Growth and Cell Division

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Publisher : Academic Press
ISBN 13 : 1483282007
Total Pages : 352 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Cell Growth and Cell Division by : R. J. C. Harris

Download or read book Cell Growth and Cell Division written by R. J. C. Harris and published by Academic Press. This book was released on 2014-07-15 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Growth and Cell Division is a collection of papers dealing with the biochemical and cytological aspects of cell development and changes in bacterial, plant, and animal systems. One paper discusses studies on the nuclear and cytoplasmic growth of ten different strains of the genus Blepharisma, in which different types of nutrition at high and low temperatures alter the species to the extent that they became morphologically indistinguishable. The paper describes the onset of death at high and low temperatures as being preceded by a decrease in the size of the cytoplasm and a corresponding decrease in the size of the macronucleus. The moribund organisms, still possessing structure, are motionless with no distinguishable macronuclear materials. Another paper presents the response of meiotic and mitotic cells to azaguanine, chloramphenicol, ethionine, and 5-methyltryptophan. The paper describes the failure of spindle action, arrest of second division, inhibition of cytokinesis, aberrant wall synthesis, and alterations in chromosome morphology in meiosis cells. In the case of mitosis, a single enzyme—thymidine phosphorylase—shows that reagents which inhibit protein synthesis also inhibit the appearance of that enzyme if the reagent is applied one day before it normally appears. Other papers discuss control mechanisms for chromosome reproduction in the cell cycle, as well as the force of cleavage of the dividing sea urchin egg. The collection can prove valuable for bio-chemists, cellular biologists, micro-biologists, and developmental biologists.

DNA : Replication and Recombination

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Publisher :
ISBN 13 :
Total Pages : 760 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis DNA : Replication and Recombination by :

Download or read book DNA : Replication and Recombination written by and published by . This book was released on 1979 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dna Replication In Plants

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Publisher : CRC Press
ISBN 13 : 1351088416
Total Pages : 477 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Dna Replication In Plants by : John A. Bryant

Download or read book Dna Replication In Plants written by John A. Bryant and published by CRC Press. This book was released on 2018-01-18 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This texts discusses DNA replication in plants including chapters on; functional chromosomal structure, the biochemistry of DNA replication, Control of DNA replication, Replication of plant organelle DNA, replication of DNA viruses in plants, and DNA damage, repair, and mutagenesis.

Tetrahymena Thermophila

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Publisher : Academic Press
ISBN 13 : 0080524958
Total Pages : 599 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Tetrahymena Thermophila by :

Download or read book Tetrahymena Thermophila written by and published by Academic Press. This book was released on 1999-09-08 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tetrahymena thermophila is emerging as a powerful experimental system for functional genetics. The ciliated protozoan offers numerous advantages, not the least of which is the ability to eliminate any specific gene of interest and then to evaluate the effect of that mutation on the living cell. Past investigations with T. thermophila have yielded several key discoveries, including dynein, catalytic RNA, and telomerase. This volume is a comprehensive resource for using Tetrahymena in the laboratory and is aimed at persons already experienced, as well as newcomers to the organism. It covers both the biological background and essential protocols for investigators rapidly turning to Tetrahymena as the experimental system of choice. Contains both theoretical and practical issues in 30 chapters contributed by the world authorities on Tetrahymena Indispensible for both the novice and the experienced researcher Overviews the history, cell biology, and genetics of the organism Describes essential protocols on the growth of cells, genetic techniques, and how to look at the cells with the microscope Illustrates how the methods can be applied to solve various cell biological problems Reviews recently developed strategies for altering gene expression

Of Urfs And Orfs

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Publisher : University Science Books
ISBN 13 : 9780935702545
Total Pages : 118 pages
Book Rating : 4.7/5 (25 download)

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Book Synopsis Of Urfs And Orfs by : Russell F. Doolittle

Download or read book Of Urfs And Orfs written by Russell F. Doolittle and published by University Science Books. This book was released on 1986 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: In these days of facile cloning and rapid DNA sequencing, it is not uncommon for investigators to find themselves with a DNA sequence that may or may not code for a known gene product. The sequence is 'open' when read in an appropriate frame, which is to say that there is a long run of amino acid codons before the appearance of a terminator codon. How can we find out if this 'unidentified reading frame' (URF) really codes for a genuine protein, and how can we identify it if it exists? There are two general strategies, both of which can also be applied to the characterization of any 'open reading frame' (ORF), whether or not it has been 'identified'. The first and simplest approach involves computer searching and analysis; the second employs antibodies raised against synthetic peptides patterned on the sequence of the expected gene product. Both methods have been used with great success by many investigators. Each has, nonetheless, its pitfalls and frustrations. This primer is meant to guide the researcher past those obstacles as much as possible. Graduate students and researchers interested in amino acid sequencing; molecular biologists, biochemists, chemists, and biotechnologists.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Ciliated Protozoa

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Publisher : Springer Science & Business Media
ISBN 13 : 1402082398
Total Pages : 627 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Ciliated Protozoa by : Denis Lynn

Download or read book The Ciliated Protozoa written by Denis Lynn and published by Springer Science & Business Media. This book was released on 2008-06-24 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: distances between groups of ciliates were as vast as significant hurdles to obtain copyright permissions the genetic distances between plants and animals for the over 1,000 required illustrations, and I put – THE major eukaryotic kingdoms at that time! the publication schedule ahead of this element. I continued to collaborate with Mitch, and in There are a number of significant illustrated guides 1991 my first “molecular” Magisterial student, to genera and species that have recently been pub- Spencer Greenwood, published an article estab- lished. References are made to these throughout lishing 1990 or thereabouts as the beginning of the book as sources that readers can consult for this the “Age of Refinement” – the period when gene aspect of ciliate diversity. A future project that I am sequencing techniques would deepen our under- contemplating is an illustrated guide to all the valid standing of the major lines of evolution within ciliate genera.

Cell Synchrony

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Publisher : Academic Press
ISBN 13 : 1483268977
Total Pages : 409 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Cell Synchrony by : Ivan L. Cameron

Download or read book Cell Synchrony written by Ivan L. Cameron and published by Academic Press. This book was released on 2013-10-02 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Synchrony: Studies in Biosynthetic Regulation focuses on the processes, principles, applications, methodologies, and approaches involved in biosynthetic regulation, including chromosome replication, cellular biosynthesis, and enzyme synthesis. The selection first takes a look at the theory of synchronous cultures, synchronous replication of the chromosome in Bacillus subtilis, and chromosome replication in Escherichia coli. Discussions focus on attempts to characterize the physical state of replicating DNA, cell division and the regulation of chromosome replication, regulation of sequential chromosome synthesis, synchrony of chromosome replication, and determination of the cell doubling-time distribution function from the decay of synchronization. The text then examines nuclear events in synchronously dividing yeast cultures, periodic enzyme synthesis in synchronous cultures of yeast, and light-induced synchronous sporulation of a myxomycete. Topics include periodicity of enzyme synthesis, use of synchronous cultures for studying cellular biosynthesis, and cytological observations on synchronously dividing cultures. The book explores the effects of temperature on the mitotic cycle of normal and synchronized mammalian cells; behavior of sulfhydryl groups in synchronous division; and morphogenetic and macromolecular aspects of synchronized Tetrahymena. The selection is highly recommended for researchers interested in biosynthetic regulation.

Marine Genetics

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792361473
Total Pages : 242 pages
Book Rating : 4.3/5 (614 download)

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Book Synopsis Marine Genetics by : Antonio M. Solé-Cava

Download or read book Marine Genetics written by Antonio M. Solé-Cava and published by Springer Science & Business Media. This book was released on 2000-05-31 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Workshop on Marine Genetics - Rio 98

Transgenerational Epigenetics

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Publisher : Academic Press
ISBN 13 : 9780128163634
Total Pages : 0 pages
Book Rating : 4.1/5 (636 download)

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Book Synopsis Transgenerational Epigenetics by :

Download or read book Transgenerational Epigenetics written by and published by Academic Press. This book was released on 2019-05-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.

The Genetic Mechanism and the Origin of Life

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Publisher : Springer Science & Business Media
ISBN 13 : 146842436X
Total Pages : 567 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Genetic Mechanism and the Origin of Life by : Lawrence Dillon

Download or read book The Genetic Mechanism and the Origin of Life written by Lawrence Dillon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: As shown in the text, there can be little doubt that the genetic mechanism is, for all practical purposes, equivalent to life itself. Consequently, it is unrealistic to seek knowledge of the origin of life and its subsequent evolution without si multaneously searching for an understanding of how this apparatus arose and evolved. Fortunately, the annual publication over the recent years of thousandS" of papers dealing with the genetic processes has brought the state of knowledge to a level where a synthesis of their major details in relation to life's history is feasible. Because of the voluminous body of literature, no single book can pos sibly treat all the ramifications of this fundamental subject; subdivision into multiple volumes is necessary. This volume, the first of a trilogy, explores the molecular aspects of the problem in connection with the precellular aspects up to the point of the origin of the cell. The second, currently in progress, is con cerned with the subsequent evolution of the cell as revealed by the energy related organelles and their genetic apparatuses and by ultrastructural details of other cellular parts. The third volume, as presently planned, deals with devel opmental, immunological, and other complexities at the organismic level and, in so doing, throws additional light on basic properties of the genetic processes themselves. Thus, the genetic apparatus provides the warp, and evolution the woof, of the intricate fabric that emerges.

Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung

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Publisher : Springer Science & Business Media
ISBN 13 : 3642662897
Total Pages : 199 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung by : W. Arber

Download or read book Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung written by W. Arber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Management of Legionella in Water Systems

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Publisher : National Academies Press
ISBN 13 : 030949382X
Total Pages : 291 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Management of Legionella in Water Systems by : National Academies of Sciences, Engineering, and Medicine

Download or read book Management of Legionella in Water Systems written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-02-20 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.

DNA Topoisomerases and Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1461403235
Total Pages : 443 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis DNA Topoisomerases and Cancer by : Yves Pommier

Download or read book DNA Topoisomerases and Cancer written by Yves Pommier and published by Springer Science & Business Media. This book was released on 2011-09-21 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.

Epigenetics

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Publisher : CSHL Press
ISBN 13 : 0879697245
Total Pages : 503 pages
Book Rating : 4.8/5 (796 download)

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Book Synopsis Epigenetics by : C. David Allis

Download or read book Epigenetics written by C. David Allis and published by CSHL Press. This book was released on 2007 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.

Biology of Tetrahymena

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Publisher :
ISBN 13 :
Total Pages : 528 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Biology of Tetrahymena by : Alfred Marlyn Elliott

Download or read book Biology of Tetrahymena written by Alfred Marlyn Elliott and published by . This book was released on 1973 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: