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Dna Mediated Assembly Of Nanostructured Materials
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Book Synopsis DNA Mediated Assembly of Nanostructured Materials by : So-Jung Park
Download or read book DNA Mediated Assembly of Nanostructured Materials written by So-Jung Park and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on this observation, a DNA array detection method was developed in which the binding of Au nanoparticles functionalized with oligonucleotides led to conductivity changes associated with target-probe binding events. The binding events localize gold nanoparticles in an electrode gap; silver deposition facilitated by these nanoparticles bridges the gap and leads to readily measurable conductivity changes. Using this method, we have detected target DNA at concentrations as low as 500 fM with a point mutation selectivity factor of ∼100,000:1. These unprecedented capabilities point towards a way of eliminating the need for polymerase chain reaction (PCR) in DNA detection.
Download or read book DNA Nanotechnology written by Chunhai Fan and published by Springer Nature. This book was released on 2020-09-07 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. The chapter "DNA-Programmed Chemical Synthesis of Polymers and Inorganic Nanomaterials" is available open access under a CC BY 4.0 License via link.springer.com.
Book Synopsis DNA-mediated Self-assembly of Nanostructures by : Björn Högberg
Download or read book DNA-mediated Self-assembly of Nanostructures written by Björn Högberg and published by . This book was released on 2007 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Protein Self-Assembly by : Jennifer J. McManus
Download or read book Protein Self-Assembly written by Jennifer J. McManus and published by Humana. This book was released on 2020-08-08 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
Book Synopsis Engineering of DNA-mediated Assemblies for Biosensing Applications by : Phyllis F. Xu
Download or read book Engineering of DNA-mediated Assemblies for Biosensing Applications written by Phyllis F. Xu and published by . This book was released on 2013 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally known as the genetic code, in recent years DNA has been engineered in new ways and applied toward novel applications in materials science and bio-nanotechnology. The nanometer features and highly specific base-pairing of DNA has enabled its use to build complex 2- and 3D nano-architectures and nano-structures. Specific DNA scaffolds include branched DNA junctions, 2D and 3D DNA "tiles" and "bricks", and DNA hydrogels that can be used for applications across various fields of materials science. Another unique feature of DNA is its ability to bind other materials through molecular recognition which has made the use of DNA aptamer or DNA-protein conjugates highly useful for applications in biosensing and identification. The main focus of this thesis is to demonstrate the use of DNA as an invaluable tool for engineering specific nanostructures for biosensing. The first chapter introduces the basics of DNA and current research in various DNA structures and assemblies and their applications. The second and third chapters describe the self-assembly of two structurally different nanomaterials using DNA, carbon nanotubes and gold nanoparticles. In the second chapter, the successful large-scale alignment of carbon nanotubes on a surface is shown. The study goes into the factors that affect the quality of alignment, including salt concentration, length of DNA, and annealing. In the third chapter, we show how DNA can be used to engineer discrete gold nanocrystal assemblies-"nanodumbbells"- that can adopt different structural conformations through DNA interactions. By incorporating DNA aptamers in the nanoparticle structure, these nanodumbbells can be used to sense particular analytes in solution. Chapter 4 continues the study of the nanodumbbell structures and their potential use as surface-enhanced Raman spectroscopy (SERS) biosensors. A large measurable difference in Raman signal was experimentally obtained from the two distinct nanodumbbell conformations. This was compared with theoretical studies of SERS enhancement to validate the signals produced. We were also able to show the successful detection of an analyte, ATP, using the DNA-mediated probe and SERS detection method.
Book Synopsis Structural DNA Nanotechnology by : Nadrian C. Seeman
Download or read book Structural DNA Nanotechnology written by Nadrian C. Seeman and published by Cambridge University Press. This book was released on 2015 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the founder of the field, this is a comprehensive and accessible introduction to structural DNA nanotechnology.
Book Synopsis Synthesis and Assembly of DNA-modified Nanostructured Materials by : Zhi Li
Download or read book Synthesis and Assembly of DNA-modified Nanostructured Materials written by Zhi Li and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation describes a series of experiments aimed at developing new synthetic methods towards DNA-modified nanostructured materials, and it also explores new schemes for the 'bio-inspired' rational assembly of such materials.
Book Synopsis Nanomaterials by : Charles M. Lukehart
Download or read book Nanomaterials written by Charles M. Lukehart and published by John Wiley & Sons. This book was released on 2013-02-19 with total page 1405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connecting inorganic chemistry to the hottest topic in materials science, this timely resource collects the contributions made by leading inorganic chemists towards nanomaterials research. The second volume in the “Wiley Encyclopedia of Inorganic Chemistry Methods and Applications Series,” this signature title concentrates on recent developments in the field and includes all key topics such as nanowires, nanotubes, biomineralization, supramolecular materials and much more. This volume is also available as part of Encyclopedia of Inorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007 to 2010, representing areas of key developments in the field of inorganic chemistry published in the Encyclopedia of Inorganic Chemistry. Find out more.
Book Synopsis DNA-mediated Gold Nanoparticle Assembly by : Kyrylo Zagorovsky
Download or read book DNA-mediated Gold Nanoparticle Assembly written by Kyrylo Zagorovsky and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique physicochemical properties of nanomaterials offer novel methodologies for disease treatment and diagnosis. Dynamic nanoparticle assemblies are adding an additional level of functionality and flexibility by combining multiple nanoparticle types into structures with stimuli-responsive size and surface chemistry. DNA-mediated gold nanoparticles assemblies are offering the most functional and versatile platform, which combines DNA addressability with large surface area, monodispersity, and easy functionalization of gold nanoparticles. Assembly size determines their application, with smaller nanoassemblies particularly suitable for drug delivery, and larger microassemblies used for biosensing. Despite a number of published studies, no in vivo examples or clinically ready biosensors have been reported. Therefore, the goal of this thesis was to identify the barriers for translation in both fields and to develop methods to overcome these limitations. To this end core-satellite nanoassemblies were designed for in vivo delivery, which efficiently protected loaded cargo and minimized macrophage recognition. Their controllable serum stability could be used as the mechanism of cargo release. In vivo nanoassemblies showed longer circulation half-life, improved tumour targeting, and renal bioelimination. In parallel, larger microassembly structures were combined with DNA enzyme signal amplification to generate a novel infectious pathogen biosensor. The assay was particularly suited for point-of-care setting with cheap and stable components and simple, fast, and specific colourimetric readout that could assay multiple targets in parallel. To demonstrate its clinical readiness, the assay was adapted for detection of a panel of five urinary tract infection bacteria. All targets were successfully identified in parallel at clinically relevant concentrations. Preliminary tests with E. coli patient samples confirmed clinical detection with good sensitivity and excellent specificity. This work presents a novel DNA-mediated gold nanoparticle assembly platform that is ready for in vivo translation and clinical in vitro diagnostics.
Book Synopsis Emerging Applications of Nanoparticles and Architectural Nanostructures by : Abdel Salam Hamdy Makhlouf
Download or read book Emerging Applications of Nanoparticles and Architectural Nanostructures written by Abdel Salam Hamdy Makhlouf and published by William Andrew. This book was released on 2018-03-22 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Applications of Nanoparticles and Architecture Nanostructures: Current Prospects and Future Trends discusses the most important current applications of nanoparticles and architecture nanostructures in a comprehensive, detailed manner. The book covers major applications of nanoparticles and architecture nanostructures, taking into account their unusual shapes and high surface areas. In particular, coverage is given to applications in aerospace, automotive, batteries, sensors, smart textile design, energy conversion, color imaging, printing, computer chips, medical implants, pharmacy, cosmetics, and more. In addition, the book discusses the future of research in these areas. This is a valuable reference for both materials scientists, chemical and mechanical engineers working both in R&D and academia who want to learn more on how nanoparticles and nanomaterials are commercially applied. - Provides an in-depth look at the properties of nanoparticles and architecture nanostructures in terms of their applicability for industrial uses - Analyzes the most recent advances and industrial applications of different types of nanoparticles and architecture nanostructures, taking into account their unusual structures and compositions - Identifies novel nanometric particles and architectures that are of particular value for applications and the techniques required to use them effectively
Book Synopsis UV-VIS and Photoluminescence Spectroscopy for Nanomaterials Characterization by : Challa S.S.R. Kumar
Download or read book UV-VIS and Photoluminescence Spectroscopy for Nanomaterials Characterization written by Challa S.S.R. Kumar and published by Springer Science & Business Media. This book was released on 2013-02-19 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second volume of a 40-volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about UV-visible and photoluminescence spectroscopy for the characterization of nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume essential reading for research scientists in academia and industry in the related fields.
Book Synopsis Materials Science of DNA by : Jung-II Jin
Download or read book Materials Science of DNA written by Jung-II Jin and published by CRC Press. This book was released on 2016-04-19 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of materials science and technology has undergone revolutionary advances due to the development of novel analytical tools, functional materials, and multidisciplinary approaches to engineering. Additionally, theoretical predictions combined with increasingly improved models and computational capabilities are making impressive contribution
Book Synopsis Self-Assembled Bio-Nanomaterials by : Gang Wei
Download or read book Self-Assembled Bio-Nanomaterials written by Gang Wei and published by MDPI. This book was released on 2020-03-25 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomolecular self-assembly provides a green, facile, and highly effective method to synthesize various functional nanomaterials that have exhibited considerable potential in the fields of nanotechnology, materials science, biomedicine, tissue engineering, food science, energy storage, and environmental science. In this collection of articles, we presented recent advance in the synthesis, characterization, and applications of self-assembled bio-nanomaterials. In a comprehensive review article, the controlled self-assembly of biomolecules including DNA, protein, peptide, enzymes, virus, and biopolymers via internal interactions and external simulations is introduced and discussed in detail. In other research articles, the self-assembly of DNA, protein, peptide, bio-drugs, liquid crystal polycarbonates, and diblock copolymers to various biomimetic/bioinspired nanomaterials and their potential applications in nanopatterning, sensors/biosensors, drug delivery, anti-parasite, and water purification are demonstrated.
Book Synopsis Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine by : Alok Pandya
Download or read book Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine written by Alok Pandya and published by Academic Press. This book was released on 2022-08-04 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormous wealth of examples in biology for the development of complex, functional structures. (3) It can incorporate biological structures directly as components in the final systems. (4) It requires that the target self-assembled structures be thermodynamically most stable with relatively defect-free and self-healing. In this book, we cover the various emerging self-assembled nanostructured objects including molecular machines, nano-cars molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nano-flakes, nano-cubes, nano-disks, nanorings, DNA origami, transmembrane channels, and vesicles. These self-assembled materials are used for sensing, drug delivery, molecular recognition, tissue engineering energy generation, and molecular tuning. - Provides a basic understanding of how to design, and implement various self-assembled nanobiomaterials - Covers principles implemented in the constructions of novel nanostructured materials - Offers many applications of self-assemblies in fluorescent biological labels, drug and gene delivery, bio-detection of pathogens, detection of proteins, probing of DNA structure, tissue engineering, and many more
Book Synopsis Templated DNA Nanotechnology by : Thimmaiah Govindaraju
Download or read book Templated DNA Nanotechnology written by Thimmaiah Govindaraju and published by CRC Press. This book was released on 2019-01-30 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic acids have structurally evolved over billions of years to effectively store and transfer genetic information. In the 1980s, Nadrian Seeman’s idea of constructing a 3D lattice from DNA led to utilizing DNA as nanomolecular building blocks to create emergent molecular systems and nanomaterial objects. This bottom-up approach to construct nanoscale architectures with DNA marked the beginning of a new field, DNA nanotechnology, contributing significantly to the broad area of nanoscience and nanotechnology. The molecular architectonics of small "designer" molecules and short DNA sequences through complementary binding interaction engenders well-defined functional nanoarchitectures with realistic applications in areas ranging from biology to materials science and is termed "DNA nanoarchitectonics." This book discusses novel approaches adapted by leading researchers from all over the world to create functional nucleic acid molecular systems and nanoarchitectures. Individual chapters contributed by active practitioners provide fundamental and advanced knowledge emanated from their own and others’ work. Each chapter includes numerous illustrations, historical perspectives, case studies and practical examples, critical discussions, and future prospects. This book can serve as a practical handbook or as a textbook for advanced undergraduate- and graduate-level students of nanotechnology and DNA nanotechnology, supramolecular chemistry, and nanoarchitectonics and researchers working on macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in sensors, biosensors, nanoswitches and nanodevices, diagnostics, drug delivery, and therapeutics.
Book Synopsis Introduction To Nanoscience And Nanomaterials by : Dinesh C Agrawal
Download or read book Introduction To Nanoscience And Nanomaterials written by Dinesh C Agrawal and published by World Scientific Publishing Company. This book was released on 2013-05-20 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is aimed primarily at the senior undergraduate and first year graduate students from the various engineering and sciences departments including physics, chemistry, materials engineering, chemical engineering, electrical engineering, mechanical engineering, bioengineering, and biology. Researchers in the areas of nanomaterials and nanoscience will also find the book useful for building the background necessary to understand the current literature and as a reference book. The text assumes only a basic level of competency in physics, chemistry and mathematics. Some of the background material and introductory matter are included in the first few chapters and as appendices. Although this material may be familiar to some of the students, it is the author's experience after teaching such a course for many years that this can not be taken for granted and moreover, serves as a ready reference to understand the text.As the area of nanoscience, nanotechnology and nanomaterials is a fast developing one, an approach which equips the students to comprehend the developing field rather than providing a large volume of information is essential. With this in view, while providing a broad perspective, the book emphasizes basics of nanoscience and nanoscale materials and goes into sufficient depth for the reader to be able to handle numerical problems. The treatment is kept at a level which is easily comprehensible to an undergraduate student. Solved examples are provided in each chapter to aid understanding and a set of problems is given at the end of each chapter.
Book Synopsis Functional Organic and Hybrid Nanostructured Materials by : Quan Li
Download or read book Functional Organic and Hybrid Nanostructured Materials written by Quan Li and published by John Wiley & Sons. This book was released on 2018-01-25 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to explore the potential of tunable functionalities in organic and hybrid nanostructured materials in a unified manner. The highly experienced editor and a team of leading experts review the promising and enabling aspects of this exciting materials class, covering the design, synthesis and/or fabrication, properties and applications. The broad topical scope includes organic polymers, liquid crystals, gels, stimuli-responsive surfaces, hybrid membranes, metallic, semiconducting and carbon nanomaterials, thermoelectric materials, metal-organic frameworks, luminescent and photochromic materials, and chiral and self-healing materials. For materials scientists, nanotechnologists as well as organic, inorganic, solid state and polymer chemists.
