Dipeptidyl Aminopeptidases In Health And Disease

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Dipeptidyl Aminopeptidases in Health and Disease

Author : Martin Hildebrandt
Publisher : Springer Science & Business Media
ISBN 13 : 0306479206
Total Pages : 360 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Dipeptidyl Aminopeptidases in Health and Disease by : Martin Hildebrandt

Download or read book Dipeptidyl Aminopeptidases in Health and Disease written by Martin Hildebrandt and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany. Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics: - Structure and function of dipeptidyl aminopeptidases, - DPP IV-like proteins, - Immune mechanisms and immune disorders, - Cancer and angiogenesis, - Diabetes and metabolism, - Therapeutic implications.

Dipeptidyl Aminopeptidases

Author : Uwe Lendeckel
Publisher : Springer Science & Business Media
ISBN 13 : 0387328246
Total Pages : 228 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Dipeptidyl Aminopeptidases by : Uwe Lendeckel

Download or read book Dipeptidyl Aminopeptidases written by Uwe Lendeckel and published by Springer Science & Business Media. This book was released on 2006-12-11 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive volume on Dipeptidyl Aminopeptidases that can be marketed to a wide variety of disciplines, as well as to a variety of clinicians. Leading experts in the field contribute to this state-of-the-art view on these enzymes. This book comes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent.

Dipeptidyl Aminopeptidases

Author : Uwe Lendeckel
Publisher : Springer
ISBN 13 : 9780387509754
Total Pages : 0 pages
Book Rating : 4.5/5 (97 download)

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Book Synopsis Dipeptidyl Aminopeptidases by : Uwe Lendeckel

Download or read book Dipeptidyl Aminopeptidases written by Uwe Lendeckel and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive volume on Dipeptidyl Aminopeptidases that can be marketed to a wide variety of disciplines, as well as to a variety of clinicians. Leading experts in the field contribute to this state-of-the-art view on these enzymes. This book comes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent.

Cell Surface Peptidases in Health and Disease

Author : A.J. Kenny
Publisher : Taylor & Francis
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Cell Surface Peptidases in Health and Disease by : A.J. Kenny

Download or read book Cell Surface Peptidases in Health and Disease written by A.J. Kenny and published by Taylor & Francis. This book was released on 1997-07 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells bristle with a battery of surface enzymes, of which the peptidases form the largest and best studied group. These ectopeptidases play crucial roles in many diverse biological functions, including the termination of peptide signals in the nervous system and at peripheral sites. Some of their key physiological roles, such as those of angiotensin- and endothelin-converting enzymes in generating vasoconstrictive agents and endopeptidase-24.11 in activating natriuretic peptides, enkephalins and tachykinins, have made them prime targets for the pharmaceutical industry. Interest among immunologists and haematologists was aroused when several were shown to be identical to cell-surface markers (CD antigens) on human leukocytes. Virologists have been excited to find that some double as receptors for certain viruses.

Cellular Peptidases in Immune Functions and Diseases 2

Author : Jürgen Langner
Publisher : Springer Science & Business Media
ISBN 13 : 0306468263
Total Pages : 510 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Cellular Peptidases in Immune Functions and Diseases 2 by : Jürgen Langner

Download or read book Cellular Peptidases in Immune Functions and Diseases 2 written by Jürgen Langner and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.

Cellular Peptidases in Immune Functions and Diseases

Author : Siegfried Ansorge
Publisher : Springer Science & Business Media
ISBN 13 : 1475796137
Total Pages : 328 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Cellular Peptidases in Immune Functions and Diseases by : Siegfried Ansorge

Download or read book Cellular Peptidases in Immune Functions and Diseases written by Siegfried Ansorge and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an international conference held in Magdeburg, Germany, November 3-5, 1996

Bioactive Food Peptides in Health and Disease

Author : Blanca Hernández-Ledesma
Publisher : BoD – Books on Demand
ISBN 13 : 9535109642
Total Pages : 279 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Bioactive Food Peptides in Health and Disease by : Blanca Hernández-Ledesma

Download or read book Bioactive Food Peptides in Health and Disease written by Blanca Hernández-Ledesma and published by BoD – Books on Demand. This book was released on 2013-01-30 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Bioactive Food Peptides in Health and Disease" highlights recent developments on bioactive food peptides for the promotion of human health and the prevention/management of chronic diseases. The book provides a comprehensive revision of bioactive peptides obtained from both animal and plant food sources. Aspects related to their bioactivity, mechanism of action, and bioavailability are extensively described along the different chapters. Also, the chapters describe the impact of bioactive peptides on the physiological absorption, regulation and disease prevention. The book also covers the recent technological advances for the production of food peptides. Bioactive Food Peptides in Health and Disease provides updated and interesting information, being a good reference book for nutritional and food scientists, biochemists, industry producers, and consumers.

Aminopeptidases in Biology and Disease

Author : Nigel M. Hooper
Publisher : Springer Science & Business Media
ISBN 13 : 1441988696
Total Pages : 347 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Aminopeptidases in Biology and Disease by : Nigel M. Hooper

Download or read book Aminopeptidases in Biology and Disease written by Nigel M. Hooper and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aminopeptidases in Biology and Disease provides a comprehensive review of the emerging role of aminopeptidases in a range of biological processes and disease situations. Processes as diverse as angiogenesis, antigen presentation, neuropeptide and hormone processing, pregnancy and reproduction, protein turnover, memory, inflammation, tumour growth, cancer and metastasis, blood pressure and hypertension all critically involve one or more aminopeptidases. The individual chapters have been written by experts in the field who have provided detailed accounts of the central roles played by various aminopeptidases in biology and disease.

Significant Pharmaceuticals Reported in US Patents

Author : Thomas F. DeRosa
Publisher : Elsevier
ISBN 13 : 0080480918
Total Pages : 701 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Significant Pharmaceuticals Reported in US Patents by : Thomas F. DeRosa

Download or read book Significant Pharmaceuticals Reported in US Patents written by Thomas F. DeRosa and published by Elsevier. This book was released on 2010-07-07 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant Pharmaceuticals Reported in US Patents identifies the next generation of pharmaceuticals reported in US Patents. This "hands-on" title provides explicit laboratory methods for preparing the most recent and effective medications. Each entry documents the biological testing protocols used to evaluate a drug and the significance of the current treatment agent over previous methods. Pharmaceuticals are included in this review only if at least two of the following criteria were met: Effectiveness in treating an illness, Innovative, ease of preparation, synergy with existing Medications. Pharmaceuticals are reported for 27 separate classes of illness, including: AIDS, Alzheimer's Disease, Cardiovascular Disorders, Diabetes, Epilepsy, Hepatitis C, Osteoporosis, Obesity and Sleep Disorders. Significant Pharmaceuticals Reported in US Patents has been designed to be used as both a reference and synthetic guide for pharmaceutical, medicinal and organic chemists and graduate students. Researchers working in other areas will also find the information valuable as in many instances intermediates or the next generation pharmaceutical are readily convertible into other industrial products including: anti-oxidants, chemical additives, herbicides, polymer precursors, water purification agents. Clear structural depictions of reagents and chemical transformations have been supplied to permit the identification of other future applications. Identifies next generation pharmaceuticals Provides practical preparation methods for each active agent and derivatives Documents the analytical characterization and biological testing results of active agents

Taurine 5

Author : John B. Lombardini
Publisher : Springer Science & Business Media
ISBN 13 : 146150077X
Total Pages : 574 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Taurine 5 by : John B. Lombardini

Download or read book Taurine 5 written by John B. Lombardini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Taurine Symposium- "Taurine: Beginning the 21'' Century"- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first taurine symposium was organized by Ryan Huxtable in Tucson, Arizona. Since that date, taurine symposia have been held approximately every two years held in various cities and resort areas around the world. Taurine investigators have had the privilege of attending these scientific meetings on three continents - Asia, Europe, and North America. Since the initial meeting in 1975, a central question addressed during many of the symposia has been: "What is physiological, pharmacological, nutritional, and pathological role of taurine?". Although taurine has been established as an important osmolyte, it appears to affect many other biological processes. However, the exact mechanism(s) by "which taurine acts" has not yet been definitively answered. In Kauai, the patticipants discussed many topics and asked many questions regarding the role and actions of taurine.

The Genus Yersinia

Author : Mikael Skurnik
Publisher : Springer Science & Business Media
ISBN 13 : 0306484161
Total Pages : 484 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis The Genus Yersinia by : Mikael Skurnik

Download or read book The Genus Yersinia written by Mikael Skurnik and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the eighth time the yersiniologists all over the world gathered together when the International Symposium on Yersinia was organized by University of Turku and Turku Microbiology Society in Turku, Finland. Over 250 delegates from 28 countries attended the Symposium. The Symposium logo (Picture 4, next page) presents a bacteriophage attached to the surface of the bacterium. One can easily imagine that most of the aspects covered in this Symposium are included in the logo: the bacteriophage genome encodes for structural proteins, adhesins and effector proteins that interact with the host cell in most intricate ways to carry out their mission. Life of the bacteriophage depends on the tightly regulated interplay between the phage and the host proteins. This all is also true between Yersinia and the different hosts and environments it encounters during its life cycle. This Symposium Proceedings volume is based on the oral and poster presentations given during the Symposium. The volume has been divided into six parts covering topics such as genomics, surface structures, bacteriophages, molecular and cellular pathogenesis, molecular epidemiology and diagnostics, gene regulation, clinical aspects and vaccines. These topics reflect righteously the present trends in the bacteriology research.

Yogurt in Health and Disease Prevention

Author : Nagendra P. Shah
Publisher : Academic Press
ISBN 13 : 0128052724
Total Pages : 572 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Yogurt in Health and Disease Prevention by : Nagendra P. Shah

Download or read book Yogurt in Health and Disease Prevention written by Nagendra P. Shah and published by Academic Press. This book was released on 2017-05-26 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yogurt in Health and Disease Prevention examines the mechanisms by which yogurt, an important source of micro- and macronutrients, impacts human nutrition, overall health, and disease. Topics covered include yogurt consumption’s impact on overall diet quality, allergic disorders, gastrointestinal tract health, bone health, metabolic syndrome, diabetes, obesity, weight control, metabolism, age-related disorders, and cardiovascular health. Modifications to yogurt are also covered in scientific detail, including altering the protein to carbohydrate ratios, adding n-3 fatty acids, phytochemical enhancements, adding whole grains, and supplementing with various micronutrients. Prebiotic, probiotic, and synbiotic yogurt component are also covered to give the reader a comprehensive understanding of the various impacts yogurt and related products can have on human health. Health coverage encompasses nutrition, gastroenterology, endocrinology, immunology, and cardiology Examines novel and unusual yogurts as well as popular and common varieties Covers effects on diet, obesity, and weight control Outlines common additives to yogurts and their respective effects Reviews prebiotics, probiotics, and symbiotic yogurts Includes practical information on how yogurt may be modified to improve its nutritive value

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1828 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ectopeptidases

Author : Jürgen Langner
Publisher : Springer Science & Business Media
ISBN 13 : 9780306467882
Total Pages : 336 pages
Book Rating : 4.4/5 (678 download)

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Book Synopsis Ectopeptidases by : Jürgen Langner

Download or read book Ectopeptidases written by Jürgen Langner and published by Springer Science & Business Media. This book was released on 2002-02-28 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea to compile recent results on the ectoenzymes aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 arose from the great interest given by readers world-wide to the two proceedings volumes edited by us in 1997 and 2000 (Ansorge and Langner, 1997; Langner and Ansorge, 2000). These volumes contained the presentations at two symposia held in Magdeburg (Germany) in 1996 and 1999 under the title "Cellular peptidases in immune functions and diseases", which was also the name of the Sonderforschungsbereich in Magdeburg, sponsored by the Deutsche Forschungsgemeinschaft between 1995 and 2001. Our groups in Magdeburg and Halle during the last two decades have provided results on these two enzymes in cells of the hematopoietic system that justify a review in an edited monograph like the present one (see the reviews by Kahne et at. , 1999; Lendeckel et at. ,1999; Riemann et at. , 1999). There are, however, many other groups in Europe, US and Japan which made important contributions to this field and particularly in topics improving the understanding of physiological and pathophysiological roles ofAPN/CD13 and DPIV/CD26. Therefore we decided to invite some of them to contribute reviews of their results to this book. Having worked for about 40 years in the field of proteolysis, for both of us to see the development of activities and knowledge from protein chemistry and enzymology to physiology and pathophysiology and even to therapy is very stimulating and fascinating. Of course, this development also reflects the dramatic improvement and refinement of methods.

Index of Conference Proceedings

Author : British Library. Document Supply Centre
Publisher :
ISBN 13 :
Total Pages : 870 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Index of Conference Proceedings by : British Library. Document Supply Centre

Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 2003 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polyomaviruses and Human Diseases

Author : Nasimul Ahsan
Publisher : Springer Science & Business Media
ISBN 13 : 0387329579
Total Pages : 383 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Polyomaviruses and Human Diseases by : Nasimul Ahsan

Download or read book Polyomaviruses and Human Diseases written by Nasimul Ahsan and published by Springer Science & Business Media. This book was released on 2007-06-25 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science never solves apr oblem without creating ten more Geor ge Bernard Shaw How prophetic the above words prove to be when applied to the advances of 20th century medicine. Prior to Banting and Best, chnicians were unaware of the ravages of diabetes, patients simply wasted away and died. Following the purifica tion of insulin, clinicians now had to deal with diabetic retinopathy, diabetic neph ropathy and all the other complications of long-term diabetes. A little over 50 years ago, the first successful human kidney transplant was performed in Boston. The first 30 years of the experience had successes when compared to the alternative but were a constant struggle to get even 50% of the grafts from deceased donors to survive more than a year. However, the science continued to advance knowledge of the immune response. With this came more and increasingly powerful tools for the clinician. Suddenly, success rates of 80-90% at one year were attainable. With this success came new problems, new complications and clinicians now had to worry about the long-term consequences of their therapy as patients were surviving with functional grafts for extended periods. A particular infectious complication evolved with the application of ever more powerful immunosuppressant drugs. Astute clinicians noted that occasionally cellular rejections seemed to get worse with steroids. Despite their best efforts and the use of powerful drugs, patients lost their grafts to overwhelming interstitial infiltrates not seen before.

Zinc Metalloproteases In Health And Disease

Author : NM Hooper
Publisher : CRC Press
ISBN 13 : 1482272768
Total Pages : 357 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Zinc Metalloproteases In Health And Disease by : NM Hooper

Download or read book Zinc Metalloproteases In Health And Disease written by NM Hooper and published by CRC Press. This book was released on 1996-07-30 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The zinc metalloproteases are a diverse group of enzymes which are becoming increasingly important in a variety of biological systems. Their major function is to break down proteins. This text presents recent research results on the biochemistry and molecular biology of these enzymes.