Diffusion Weighted Magnetic Resonance Imaging Mono And Bi Exponential Signal Decay And Post Processing Applications In The Brain

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Diffusion-weighted magnetic resonance imaging: mono- and bi-exponential signal decay and post processing applications in the brain

Author : Szilvia Anett Nagy
Publisher :
ISBN 13 :
Total Pages : 60 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Diffusion-weighted magnetic resonance imaging: mono- and bi-exponential signal decay and post processing applications in the brain by : Szilvia Anett Nagy

Download or read book Diffusion-weighted magnetic resonance imaging: mono- and bi-exponential signal decay and post processing applications in the brain written by Szilvia Anett Nagy and published by . This book was released on 2013 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ziel dieser Studie ist Veränderungen des bi-exponentiellen Signals bei Patienten mit mesialer Temporallappen-Epilepsie und Hippocampus-Sklerose zu charakterisieren. Dies erfolgt durch Vergleich zu einer im Alter und Geschlecht angepaßten Referenzgruppe. Diffusionsparameter werden nach diffusionsgewichteter Bildgebung an 3-Tesla MRT, mit mono- und bi-exponentiellem Verfahren berechnet. Dabei werden die sog. MRT-Rohdaten mit Hilfe von Matlab Program, FMRIB-Software und SPSS Statistik-Analyse analisiert und bewertet. Bi-exponentielle Anpassungsfunktion ergibt Parameter von rapiden und langsamen Diffusionskomponenten und deren Fraktion, wobei eine Analyse mit b-Werten bis 3000 s/mm2 wird realisiert. Resultat mono-exponentieller Approximation zeigt Amygdala, Hippocampus und normal erscheinende Weißgewebe-Gebiete mit erhöhter Apparent-Diffusion. Hingegen liegen Fraktionswerte der langsamen Diffusionskomponenten niedriger im Vergleich zu identischen Parameter der Referenzgruppe. Diese Daten demonstrieren: Veränderungen der molekularen Umgebung bei Patienten mit unilateraler mesialer Temporallappen-Epilepsie beeinflussen sowohl Grau- wie Weißgewebe-Strukturen und verursachen eine Verschiebung einzelner Wasserfraktionen im Gehirn.*****The aim of this work is to characterize bi-exponential diffusion signal changes in mesial temporal lobe epilepsy patients with hippocampal sclerosis compared to an age- and sex-matched control group. Diffusion parameters are measured by mono- and bi-exponential approaches after acquiring diffusion-weighted images on a 3T MRI system. The raw data is analyzed using Matlab program, FMRIB software and SPSS statistical application. Bi-exponential fits yield parameters for the fast and the slow diffusion components and the fraction of them using high b-value analysis up to 3000 s/mm2. As a result of mono-exponential fitting, amygdala, hippocampus and normal appearing white matter show increased apparent diffusion, while the fraction of the slow diffusion component is decreased compared to the control group. These data demonstrate that the alteration in molecular environment of unilateral mesial temporal lobe epilepsy affects diffusion in both gray and white matter structures causing the shift between different water fractions.

Intravoxel Incoherent Motion (IVIM) MRI

Author : Denis Le Bihan
Publisher : CRC Press
ISBN 13 : 0429763492
Total Pages : 563 pages
Book Rating : 4.4/5 (297 download)

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Book Synopsis Intravoxel Incoherent Motion (IVIM) MRI by : Denis Le Bihan

Download or read book Intravoxel Incoherent Motion (IVIM) MRI written by Denis Le Bihan and published by CRC Press. This book was released on 2018-11-05 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: First book ever on the topic Discusses current concepts and methodological issues for the successful implementation of IVIM MRI to investigate tissue perfusion non-invasively Covers a wide range of clinical applications Contributions by leading experts in the field from USA, Europe, and Asia and written with a good balance of methodological and clinical chapters Includes an extensive bibliography for further reading

Diffusion MRI Outside the Brain

Author : Antonio Luna
Publisher : Springer Science & Business Media
ISBN 13 : 364221052X
Total Pages : 416 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Diffusion MRI Outside the Brain by : Antonio Luna

Download or read book Diffusion MRI Outside the Brain written by Antonio Luna and published by Springer Science & Business Media. This book was released on 2011-11-22 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in MR technology permit the application of diffusion MRI outside of the brain. In this book, the authors present cases drawn from daily clinical practice to illustrate the role of diffusion sequences, along with other morphological and functional MRI information, in the work-up of a variety of frequently encountered oncological and non-oncological diseases. Breast, musculoskeletal, whole-body, and other applications are covered in detail, with careful explanation of the pros and cons of diffusion MRI in each circumstance. Quantification and post-processing are discussed, and advice is provided on how to acquire state of the art images, and avoid artifacts, when using 1.5- and 3-T magnets. Applications likely to emerge in the near future, such as for screening, are also reviewed. The practical approach adopted by the authors, combined with the wealth of high-quality illustrations, ensure that this book will be of great value to practitioners.

Computational Diffusion MRI

Author : Lauren O'Donnell
Publisher : Springer
ISBN 13 : 3319111825
Total Pages : 216 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Computational Diffusion MRI by : Lauren O'Donnell

Download or read book Computational Diffusion MRI written by Lauren O'Donnell and published by Springer. This book was released on 2015-02-17 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains papers presented at the 2014 MICCAI Workshop on Computational Diffusion MRI, CDMRI’14. Detailing new computational methods applied to diffusion magnetic resonance imaging data, it offers readers a snapshot of the current state of the art and covers a wide range of topics from fundamental theoretical work on mathematical modeling to the development and evaluation of robust algorithms and applications in neuroscientific studies and clinical practice. Inside, readers will find information on brain network analysis, mathematical modeling for clinical applications, tissue microstructure imaging, super-resolution methods, signal reconstruction, visualization, and more. Contributions include both careful mathematical derivations and a large number of rich full-color visualizations. Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into the clinic. This volume will offer a valuable starting point for anyone interested in learning computational diffusion MRI. It also offers new perspectives and insights on current research challenges for those currently in the field. The book will be of interest to researchers and practitioners in computer science, MR physics, and applied mathematics.

Diffusion MRI

Author : Derek K. Jones
Publisher :
ISBN 13 : 9780199828678
Total Pages : pages
Book Rating : 4.8/5 (286 download)

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Book Synopsis Diffusion MRI by : Derek K. Jones

Download or read book Diffusion MRI written by Derek K. Jones and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diffusion Weighted and Diffusion Tensor Imaging

Author : Claudia Leite
Publisher : Thieme
ISBN 13 : 162623020X
Total Pages : 467 pages
Book Rating : 4.6/5 (262 download)

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Book Synopsis Diffusion Weighted and Diffusion Tensor Imaging by : Claudia Leite

Download or read book Diffusion Weighted and Diffusion Tensor Imaging written by Claudia Leite and published by Thieme. This book was released on 2016-01-16 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion-weighted imaging (DWI) is an integral part of routine neuroimaging, used nearly universally in brain MRIs, and more recently for the spine, spinal cord, and head and neck. DWI provides clinically relevant information on conditions including stroke, infection, and neoplasms. Diffusion tensor imaging (DTI) is a powerful, newer technique with the potential for multiple protocols, including the diagnosis of mild traumatic brain injury and psychiatric disorders. Written by leading authorities in neuroradiology and radiology, Diffusion Weighted and Diffusion Tensor Imaging: A Clinical Guide provides key points and summaries on the concepts and applications required for proper implementation and interpretation of DWI and DTI. Key Features: More than 600 high-quality illustrations Protocols and applications from early childhood to older adulthood Methods to differentiate normal versus pathological states Brain edema pathophysiology and use of DWI to distinguish between cytotoxic and vasogenic edema Utilization of DWI and DTI to diagnose trauma, white matter disease, tumors, cerebrovascular disease, and head, neck, and spine disorders This concise handbook is an invaluable resource for neuroradiologists and radiologists, as well as fellows and residents in these disciplines. With the expanding use of these procedures, neuroscientists, neurologists, neurosurgeons, and psychiatrists will also find it indispensable.

Quantitative Magnetic Resonance Imaging

Author : Nicole Seiberlich
Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Quantitative Magnetic Resonance Imaging by : Nicole Seiberlich

Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Diffusion MRI

Author : Derek K Jones
Publisher : Oxford University Press
ISBN 13 : 0199708703
Total Pages : 784 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Diffusion MRI by : Derek K Jones

Download or read book Diffusion MRI written by Derek K Jones and published by Oxford University Press. This book was released on 2010-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Derek Jones, a world authority on diffusion MRI, has assembled most of the world's leading scientists and clinicians developing and applying diffusion MRI to produce an authorship list that reads like a "Who's Who" of the field and an essential resource for those working with diffusion MRI. Destined to be a modern classic, this definitive and richly illustrated work covers all aspects of diffusion MRI from basic theory to clinical application. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.

Computational Diffusion MRI

Author : Andrea Fuster
Publisher : Springer
ISBN 13 : 3319541307
Total Pages : 214 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Computational Diffusion MRI by : Andrea Fuster

Download or read book Computational Diffusion MRI written by Andrea Fuster and published by Springer. This book was released on 2017-05-11 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a valuable starting point for anyone interested in learning computational diffusion MRI and mathematical methods for brain connectivity, while also sharing new perspectives and insights on the latest research challenges for those currently working in the field. Over the last decade, interest in diffusion MRI has virtually exploded. The technique provides unique insights into the microstructure of living tissue and enables in-vivo connectivity mapping of the brain. Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into the clinic, while new processing methods are essential to addressing issues at each stage of the diffusion MRI pipeline: acquisition, reconstruction, modeling and model fitting, image processing, fiber tracking, connectivity mapping, visualization, group studies and inference. These papers from the 2016 MICCAI Workshop “Computational Diffusion MRI” – which was intended to provide a snapshot of the latest developments within the highly active and growing field of diffusion MR – cover a wide range of topics, from fundamental theoretical work on mathematical modeling, to the development and evaluation of robust algorithms and applications in neuroscientific studies and clinical practice. The contributions include rigorous mathematical derivations, a wealth of rich, full-color visualizations, and biologically or clinically relevant results. As such, they will be of interest to researchers and practitioners in the fields of computer science, MR physics, and applied mathematics.

Functional Magnetic Resonance Imaging Processing

Author : Xingfeng Li
Publisher : Springer Science & Business Media
ISBN 13 : 9400773021
Total Pages : 229 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Functional Magnetic Resonance Imaging Processing by : Xingfeng Li

Download or read book Functional Magnetic Resonance Imaging Processing written by Xingfeng Li and published by Springer Science & Business Media. This book was released on 2013-09-14 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: With strong numerical and computational focus, this book serves as an essential resource on the methods for functional neuroimaging analysis, diffusion weighted image analysis, and longitudinal VBM analysis. It includes four MRI image modalities analysis methods. The first covers the PWI methods, which is the basis for understanding cerebral flow in human brain. The second part, the book’s core, covers fMRI methods in three specific domains: first level analysis, second level analysis, and effective connectivity study. The third part covers the analysis of Diffusion weighted image, i.e. DTI, QBI and DSI image analysis. Finally, the book covers (longitudinal) VBM methods and its application to Alzheimer’s disease study.

Advanced analysis of diffusion MRI data

Author : Xuan Gu
Publisher : Linköping University Electronic Press
ISBN 13 : 9175190036
Total Pages : 93 pages
Book Rating : 4.1/5 (751 download)

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Book Synopsis Advanced analysis of diffusion MRI data by : Xuan Gu

Download or read book Advanced analysis of diffusion MRI data written by Xuan Gu and published by Linköping University Electronic Press. This book was released on 2019-11-19 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion magnetic resonance imaging (diffusion MRI) is a non-invasive imaging modality which can measure diffusion of water molecules, by making the MRI acquisition sensitive to diffusion. Diffusion MRI provides unique possibilities to study structural connectivity of the human brain, e.g. how the white matter connects different parts of the brain. Diffusion MRI enables a range of tools that permit qualitative and quantitative assessments of many neurological disorders, such as stroke and Parkinson. This thesis introduces novel methods for diffusion MRI data analysis. Prior to estimating a diffusion model in each location (voxel) of the brain, the diffusion data needs to be preprocessed to correct for geometric distortions and head motion. A deep learning approach to synthesize diffusion scalar maps from a T1-weighted MR image is proposed, and it is shown that the distortion-free synthesized images can be used for distortion correction. An evaluation, involving both simulated data and real data, of six methods for susceptibility distortion correction is also presented in this thesis. A common problem in diffusion MRI is to estimate the uncertainty of a diffusion model. An empirical evaluation of tractography, a technique that permits reconstruction of white matter pathways in the human brain, is presented in this thesis. The evaluation is based on analyzing 32 diffusion datasets from a single healthy subject, to study how reliable tractography is. In most cases only a single dataset is available for each subject. This thesis presents methods based on frequentistic (bootstrap) as well as Bayesian inference, which can provide uncertainty estimates when only a single dataset is available. These uncertainty measures can then, for example, be used in a group analysis to downweight subjects with a higher uncertainty.

Computational Diffusion MRI

Author : Noemi Gyori
Publisher : Springer Nature
ISBN 13 : 3030730182
Total Pages : 301 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Computational Diffusion MRI by : Noemi Gyori

Download or read book Computational Diffusion MRI written by Noemi Gyori and published by Springer Nature. This book was released on 2021-09-29 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers papers presented at the Workshop on Computational Diffusion MRI, CDMRI 2020, held under the auspices of the International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), which took place virtually on October 8th, 2020, having originally been planned to take place in Lima, Peru. This book presents the latest developments in the highly active and rapidly growing field of diffusion MRI. While offering new perspectives on the most recent research challenges in the field, the selected articles also provide a valuable starting point for anyone interested in learning computational techniques for diffusion MRI. The book includes rigorous mathematical derivations, a large number of rich, full-colour visualizations, and clinically relevant results. As such, it is of interest to researchers and practitioners in the fields of computer science, MRI physics, and applied mathematics. The reader will find numerous contributions covering a broad range of topics, from the mathematical foundations of the diffusion process and signal generation to new computational methods and estimation techniques for the in-vivo recovery of microstructural and connectivity features, as well as diffusion-relaxometry and frontline applications in research and clinical practice.

High Resolution Anatomic Spectroscopic and Diffusion Magnetic Resonance Imaging of the Brain

Author : Duan Xu
Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.:/5 (85 download)

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Book Synopsis High Resolution Anatomic Spectroscopic and Diffusion Magnetic Resonance Imaging of the Brain by : Duan Xu

Download or read book High Resolution Anatomic Spectroscopic and Diffusion Magnetic Resonance Imaging of the Brain written by Duan Xu and published by . This book was released on 2005 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Towards Real-time Diffusion Imaging

Author : Véronique Brion
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (867 download)

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Book Synopsis Towards Real-time Diffusion Imaging by : Véronique Brion

Download or read book Towards Real-time Diffusion Imaging written by Véronique Brion and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most magnetic resonance imaging (MRI) system manufacturers propose a huge set of software applications to post-process the reconstructed MRI data a posteriori, but few of them can run in real-time during the ongoing scan. To our knowledge, apart from solutions dedicated to functional MRI allowing relatively simple experiments or for interventional MRI to perform anatomical scans during surgery, no tool has been developed in the field of diffusion-weighted MRI (dMRI). However, because dMRI scans are extremely sensitive to lots of hardware or subject-based perturbations inducing corrupted data, it can be interesting to investigate the possibility of processing dMRI data directly during the ongoing scan and this thesis is dedicated to this challenging topic. The major contribution of this thesis aimed at providing solutions to denoise dMRI data in real-time. Indeed, the diffusion-weighted signal may be corrupted by a significant level of noise which is not Gaussian anymore, but Rician or noncentral chi. After making a detailed review of the literature, we extended the linear minimum mean square error (LMMSE) estimator and adapted it to our real-time framework with a Kalman filter. We compared its efficiency to the standard Gaussian filtering, difficult to implement, as it requires a modification of the reconstruction pipeline to insert the filter immediately after the demodulation of the acquired signal in the Fourier space. We also developed a parallel Kalman filter to deal with any noise distribution and we showed that its efficiency was quite comparable to the non parallel Kalman filter approach. Last, we addressed the feasibility of performing tractography in real-time in order to infer the structural connectivity online. We hope that this set of methodological developments will help improving and accelerating a diagnosis in case of emergency to check the integrity of white matter fiber bundles.

Introduction to Diffusion Tensor Imaging

Author : Susumu Mori
Publisher : Academic Press
ISBN 13 : 0123984076
Total Pages : 141 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Introduction to Diffusion Tensor Imaging by : Susumu Mori

Download or read book Introduction to Diffusion Tensor Imaging written by Susumu Mori and published by Academic Press. This book was released on 2013-08-02 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concepts behind diffusion tensor imaging (DTI) are commonly difficult to grasp, even for magnetic resonance physicists. To make matters worse, a many more complex higher-order methods have been proposed over the last few years to overcome the now well-known deficiencies of DTI. In Introduction to Diffusion Tensor Imaging: And Higher Order Models, these concepts are explained through extensive use of illustrations rather than equations to help readers gain a more intuitive understanding of the inner workings of these techniques. Emphasis is placed on the interpretation of DTI images and tractography results, the design of experiments, and the types of application studies that can be undertaken. Diffusion MRI is a very active field of research, and theories and techniques are constantly evolving. To make sense of this constantly shifting landscape, there is a need for a textbook that explains the concepts behind how these techniques work in a way that is easy and intuitive to understand—Introduction to Diffusion Tensor Imaging fills this gap. Extensive use of illustrations to explain the concepts of diffusion tensor imaging and related methods Easy to understand, even without a background in physics Includes sections on image interpretation, experimental design, and applications Up-to-date information on more recent higher-order models, which are increasingly being used for clinical applications

MRI from Picture to Proton

Author : Donald W. McRobbie
Publisher : Cambridge University Press
ISBN 13 : 1316688259
Total Pages : 405 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis MRI from Picture to Proton by : Donald W. McRobbie

Download or read book MRI from Picture to Proton written by Donald W. McRobbie and published by Cambridge University Press. This book was released on 2017-04-13 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.

Clinical Applications of Diffusion Imaging of the Brain, an Issue of Neuroimaging Clinics

Author : Celso Hygino
Publisher : Saunders
ISBN 13 : 9781455704682
Total Pages : 0 pages
Book Rating : 4.7/5 (46 download)

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Book Synopsis Clinical Applications of Diffusion Imaging of the Brain, an Issue of Neuroimaging Clinics by : Celso Hygino

Download or read book Clinical Applications of Diffusion Imaging of the Brain, an Issue of Neuroimaging Clinics written by Celso Hygino and published by Saunders. This book was released on 2011-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics covered in this issue are: Basic principles of Diffusion Imaging; Diffusion MR Imaging: An Important Tool in the Assessment of Brain Tumors; Diffusion MR imaging of Acute Ischemic Stroke; Diffusion Imaging in Demyelinating Diseases; Diffusion Imaging in Brain Infection; Diffusion Imaging in Brain Trauma; Diffusion Imaging in the Neonate Brain; Diffusion MR Imaging for Monitoring Treatment Response; Assessment of Brain Development; Future Horizons in Diffusion Imaging of the Brain.