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Dictyostelium Discoideum Genome Project
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Book Synopsis Dictyostelium discoideum Protocols by : Ludwig Eichinger
Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.
Book Synopsis Dictyostelium Discoideum Genome Project by :
Download or read book Dictyostelium Discoideum Genome Project written by and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Dictyostelium Discoideum Genome Project is an international collaboration between the University of Cologne, the Institute of Molecular Biotechnology in Jena, Department of Genome Analysis, the Baylor College of Medicine in Houston, the GMP, Institut Pasteur in Paris, and the Sanger Centre in Hinxton. This website is a service to the biological research community by providing unpublished DNA sequence data in a timely manner.
Book Synopsis Dictyostelium Discoideum by : William Loomis
Download or read book Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium Discoideum: A Developmental System presents D. discoideum as a model eukaryotic system to study a variety of developmental problems. The book describes the life cycle of the organism D. discoideum which exists in nature as a soil amoeba in forest detritus. The nuclei of D. discoideum contain DNA, RNA, and proteins which have properties similar to those of histones present in calf thymus nuclei. The unique sequences of the genome of the organism code for the gene products synthesize during its growth and development. One approach in genetic analyses to understanding the developmental processes of the organism is to isolate a large number of morphological mutants. The isolation process will indicate the number of variations that are open to the developing system, and will point to causal connections between stages. The text also explains that the number of cells which differentiate into stalk cells is the result of timing and mechanics of the process of culmination. Ashworth (1971) suggests that cells in pseudoplasmodia of D. discoideum adjust their positions in relation to the chemical structure of the sheath itself. A model shows how cells communicate their response to the sheath in an axial fashion. The book can prove beneficial for biochemists, micro-biologists, cellular researchers, and investigators involved in the study of cellular biology.
Book Synopsis The Development Of Dictyostelium Discoideum by : William Loomis
Download or read book The Development Of Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development of Dictyostelium discoideum consists of 11 chapters representing the 11 major aspects at which continuous progress are made in the study of Dictyostelium discoideum. This book begins with the discovery, classification, ecology, and development of Dictyostelium discoideum. It then outlines the advances in genetic manipulation and mutant isolation of the organism. Much of the advances in cell biology have been related to a better understanding of the composition and function of the cell membrane. Hence, analyses of Dictyostelium plasma membranes are collated. This reference material also describes the role of chemoattractants in organizing cell movements and the intracellular events triggered by occupancy of chemoreceptors. It also explains the understanding of the macromolecular components of the chemosensory system of Dictyostelium discoideum. It further discusses the cell motility, cell adhesion, morphogenetic signaling, cytodifferentiation, and gene expression in the species. Finally, the phenomenon of cell-type specification and regulation in this organism is addressed. This book will be valuable for those already familiar with the general outlines of Dictyostelium biology.
Book Synopsis Dictyostelium discoideum Protocols by : Ludwig Eichinger
Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Humana Press. This book was released on 2016-08-23 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a well-establish eukaryotic model organism that offers unique advantages for studying fundamental cellular processes, including signal transduction, random and directed cell motility, cytokinesis, endocytosis and vesicle transport and development. Dictyostelium is also increasingly used for the investigation of human disease genes and the crosstalk between host and pathogen. The availability of the genome sequence at a mouse click together with a whole range of supporting information and resources along with a powerful armoury of molecular genetics techniques have considerably enhanced the experimental attractiveness of D. discoideum in recent years. The second edition of Dictyostelium discoideum Protocols incorporates the most recent developments in a number of fields. The book is divided into four parts. The first part provides an introduction to the amoebozoa and community resources. The second part presents large-scale analysis methods made possible by the completion of the Dictyostelium genome sequence. The third part is dedicated to molecular genetics techniques, cell biological, biochemical and biophysical methods. The chapters in the fourth part describe the use of Dictyostelium as a model system to study vesicle formation, trafficking and infection by bacterial pathogens. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Dictyostelium discoideum Protocols, Second Edition seeks to aid scientists in the application of innovating techniques to study a range of fundamental biological processes in this attractive model organism.
Book Synopsis Dictyostelium discoideum by : Alan R. Kimmel
Download or read book Dictyostelium discoideum written by Alan R. Kimmel and published by Springer Nature. This book was released on with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Analysis of Genome Structure and Transcription in Dictyostelium Discoideum Using Three Recombinant Plasmids by : Karen Linnea Kindle Hartsuyker
Download or read book The Analysis of Genome Structure and Transcription in Dictyostelium Discoideum Using Three Recombinant Plasmids written by Karen Linnea Kindle Hartsuyker and published by . This book was released on 1978 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dictyostelium discoideum Protocols by : Ludwig Eichinger
Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Humana Press. This book was released on 2006-07-01 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.
Book Synopsis Gene Expression in Dictyostelium Discoideum by : Carol Louise Mitchell MacLeod
Download or read book Gene Expression in Dictyostelium Discoideum written by Carol Louise Mitchell MacLeod and published by . This book was released on 1979 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Organization and Expression of the Discoidin I Gene Family of Dictyostelium Discoideum by : Stephen James Poole
Download or read book The Organization and Expression of the Discoidin I Gene Family of Dictyostelium Discoideum written by Stephen James Poole and published by . This book was released on 1983 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Developmental Expression of the Dictyostelium Discoideum Ras Gene and Preliminary Detection of a Second Ras-homologous Sequence in Its Genome by : Virginia Elaine Gray
Download or read book The Developmental Expression of the Dictyostelium Discoideum Ras Gene and Preliminary Detection of a Second Ras-homologous Sequence in Its Genome written by Virginia Elaine Gray and published by . This book was released on 1987 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dictyostelium by : Richard H. Kessin
Download or read book Dictyostelium written by Richard H. Kessin and published by Cambridge University Press. This book was released on 2001-01-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.
Book Synopsis Functional and Regulatory Analyses of the Dictyostelium Discoideum G-box Binding Factor by : Jason Matthew Brown
Download or read book Functional and Regulatory Analyses of the Dictyostelium Discoideum G-box Binding Factor written by Jason Matthew Brown and published by . This book was released on 2000 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dictyostelium Discoideum by : William F. Loomis
Download or read book Dictyostelium Discoideum written by William F. Loomis and published by . This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nonmammalian Genomic Analysis by : Bruce Birren
Download or read book Nonmammalian Genomic Analysis written by Bruce Birren and published by Academic Press. This book was released on 1996-09-25 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering detailed protocols for those needing to construct a variety of maps and isolate genes, this unique book is intended to popularize the new techniques of genome analysis derived from the Human Genome Project. The power of these new methods is often most striking when applied to problems outside of human genetics, particularly the nonmammalian systems on which many researchers focus. Many of these organisms are economically important and biologically rich. Nonmammalian Genomic Analysis: A Practical Guide covers the "how to" aspects of preparation, handling, cloning, and analysis of large DNA and the creation of chromosome and genome maps. This lab manual facilitates the transfer of these technologies to small "low tech" environments and allows them to be used by those with no background in genome mapping or large-fragment cloning. Like having a local expert, this collection provides procedures for anyone, anywhere, and allows the replication of others' success. Includes detailed and clearly-written step-by-step protocols Evinces expected results and offers trouble shooting advice Provides techniques appropriate for small laboratories as well as those with limited resources Covers a broad variety of cloning systems, including single copy vectors Discusses a diverse range of organisms, from prokaryotes to eukaryotes, from single-celled organisms to highly complex organisms
Download or read book Dictyostelids written by Maria Romeralo and published by Springer. This book was released on 2013-07-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.
Book Synopsis Molecular Biology of Dictyostelium Development by : Alan R. Kimmel
Download or read book Molecular Biology of Dictyostelium Development written by Alan R. Kimmel and published by Alan R. Liss. This book was released on 1988 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:
