Diagnostic Accuracy of Sepsis: Clinical Scores Combination and Serum Biomarkers for Rapid Diagnosis and Prognosis

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Publisher : Frontiers Media SA
ISBN 13 : 2832536786
Total Pages : 104 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Diagnostic Accuracy of Sepsis: Clinical Scores Combination and Serum Biomarkers for Rapid Diagnosis and Prognosis by : Silvia Spoto

Download or read book Diagnostic Accuracy of Sepsis: Clinical Scores Combination and Serum Biomarkers for Rapid Diagnosis and Prognosis written by Silvia Spoto and published by Frontiers Media SA. This book was released on 2023-10-25 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sepsis is the first cause of death for infection accounting for 17% of intra-hospital mortality and reaching 26% in case of septic shock with estimated costs for over 24 billion of dollar per year. Early diagnosis and appropriate treatment can significantly reduce sepsis mortality however there is currently no gold standard in sepsis diagnosis. To date, it is recommended to use an improved program for sepsis, including sepsis screening for acutely ill, high-risk patients and standard operating procedures for treatment in hospitals. Sepsis screening tools are designed to promote early identification of sepsis using clinical scores and biomarkers. The combination of clinical scores and biomarkers increases the diagnostic and prognostic accuracy of sepsis, improving patient clinical management. Various clinical variables and tools are used for sepsis screening, such as vital signs, signs of infection, systemic inflammatory response syndrome (SIRS) criteria, quick Sequential Organ Failure Score (q-SOFA) or Sequential Organ Failure Assessment (SOFA) criteria, National Early Warning Score (NEWS), or Modified Early Warning Score (MEWS).

Biomarker

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Publisher : BoD – Books on Demand
ISBN 13 : 1789236665
Total Pages : 250 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Biomarker by : Ghousia Begum

Download or read book Biomarker written by Ghousia Begum and published by BoD – Books on Demand. This book was released on 2018-09-05 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of disease prognosis. Chapters in Part I focus on biomarkers for cancer, including breast cancer and pancreatic cancer, as well as circulating microRNA profiling in cancer biomarker discovery. Chapters in Part II focus on biomarkers of other diagnoses/diseases, including sepsis, childhood renal diseases, pulmonary diseases, Alzheimer's, leishmaniasis, and heart failure. This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of diseases prognosis. The book is of considerable importance for a broad range of people including researchers, clinicians, and university students.

Clinical Management of Shock

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Publisher : BoD – Books on Demand
ISBN 13 : 1838811702
Total Pages : 210 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Clinical Management of Shock by : Stanislaw P. Stawicki

Download or read book Clinical Management of Shock written by Stanislaw P. Stawicki and published by BoD – Books on Demand. This book was released on 2020-06-24 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shock is a physiological state of war! From a healthcare provider perspective, the word “shock” is associated with a mixed array of feelings, including dread, well-founded fear, and deep respect. The physiological state of shock is well recognized for the associated destructive consequences, and its successful management requires prompt identification, immediate action, and sustained effort by all members of the healthcare team. This mindset of advanced preparation and constant readiness constitutes the foundation of the modern approach toward shock – early detection and prompt treatment for optimal outcomes. Despite the heterogeneity of “shock” as a clinico-pathological entity, there are some common threads that permeate all forms and manifestations of shock, with apparent increase in observed commonalities in the more advanced (and often irreversible) stages of the systemic syndrome. When faced with shock, the body and its systems do their best to compensate for the maldistribution of oxygen and nutrients. This is known as the so-called compensated shock. Beyond that, the body loses its ability to adjust any further, thus descending into “uncompensated shock,” with a refractory state characterized by vasoplegia and irreversible cardiovascular failure. As the reader journeys through the chapters of the book, he or she will read about various biomarkers and endpoints of resuscitation, explore different types of shock (e.g., septic, hemorrhagic, anaphylactic) and learn about some of the less often discussed topics such as neurogenic and spinal shock, as well as the amniotic fluid embolism. Our goals were to keep things clinically relevant and practically oriented, thus enabling the reader to apply the newly acquired knowledge in their everyday clinical routines. As the reader progresses through the book, we hope to help stimulate further discourse and innovative thinking about the topic. In this context, it is critical that basic, translational, and clinical research on shock continues to advance. Only through ongoing scientific progress can we help improve outcomes for patients with both rare and common forms of shock.

Sepsis Management in Resource-limited Settings

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Publisher : Springer
ISBN 13 : 3030031438
Total Pages : 216 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Sepsis Management in Resource-limited Settings by : Arjen M. Dondorp

Download or read book Sepsis Management in Resource-limited Settings written by Arjen M. Dondorp and published by Springer. This book was released on 2019-02-08 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Handbook of Sepsis

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Publisher : Springer
ISBN 13 : 3319735063
Total Pages : 264 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Handbook of Sepsis by : W. Joost Wiersinga

Download or read book Handbook of Sepsis written by W. Joost Wiersinga and published by Springer. This book was released on 2018-04-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.

Hemodynamic Monitoring

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Publisher : Springer
ISBN 13 : 3319692690
Total Pages : 476 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Hemodynamic Monitoring by : Michael R. Pinsky

Download or read book Hemodynamic Monitoring written by Michael R. Pinsky and published by Springer. This book was released on 2019-02-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.

Evidence-based Laboratory Medicine

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Publisher : Amer. Assoc. for Clinical Chemistry
ISBN 13 : 9781890883904
Total Pages : 316 pages
Book Rating : 4.8/5 (839 download)

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Book Synopsis Evidence-based Laboratory Medicine by : Christopher P. Price

Download or read book Evidence-based Laboratory Medicine written by Christopher P. Price and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Shock Management

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Publisher : Springer
ISBN 13 : 9811054061
Total Pages : 147 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Essentials of Shock Management by : Gil Joon Suh

Download or read book Essentials of Shock Management written by Gil Joon Suh and published by Springer. This book was released on 2018-11-30 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of shock – septic, hemorrhagic, cardiogenic, anaphylactic, and obstructive – at all stages from initial response through to ICU admission. As well as management, the coverage encompasses pathophysiology, clinical presentation, diagnosis, and emerging trends. A further key feature is the use of a scenario-based approach to present a series of cases based on real-life experiences. Here, a narrative style and Q&A form are employed to vividly convey scenarios that may be encountered in clinical practice and to elucidate decision making in complex circumstances. When readers experience difficulty in answering the questions, the earlier sections can be consulted to identify the correct response. This book will be of great value for all health care professionals. In particular, it will be very helpful for novice or inexperienced practitioners in emergency medicine, critical care medicine, and traumatology.

Acute Pulmonary Embolism

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Publisher : Springer Science & Business Media
ISBN 13 : 3642511902
Total Pages : 202 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Acute Pulmonary Embolism by : A. Geibel

Download or read book Acute Pulmonary Embolism written by A. Geibel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.

Nephrology and Public Health Worldwide

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 331806937X
Total Pages : 369 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Nephrology and Public Health Worldwide by : G.B. Silva Junior

Download or read book Nephrology and Public Health Worldwide written by G.B. Silva Junior and published by Karger Medical and Scientific Publishers. This book was released on 2021-11-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the desirable equity worldwide, the nephrology community needs to discuss this public health issue and take part in decisions for elaboration of public health policies with more justice and equity. This book brings together key current public health problems that affect kidney function and illuminates them in contributions by an international group of nephrologists and general practitioners. The chapters review current knowledge and provide guidelines to manage these conditions and decrease the disease burden. At the end, developments in the digital era and their application to kidney disease treatment are synthesized, and a broader outlook on the future of nephrology is given. Ultimately, the publication aims to gather nephrology and public health expertise from researchers from all over the world, providing a broad vision of issues that must be discussed and overcome to guarantee a better treatment for patients with kidney diseases in the world today.

Epigenetic Biomarkers and Diagnostics

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Publisher : Academic Press
ISBN 13 : 0128019212
Total Pages : 698 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epigenetic Biomarkers and Diagnostics by : Jose Luis Garcia-Gimenez

Download or read book Epigenetic Biomarkers and Diagnostics written by Jose Luis Garcia-Gimenez and published by Academic Press. This book was released on 2015-12-07 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders. The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognostics Describes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnostics Discusses the advances in epigenomics technologies, including next-generation sequencing based tools and applications Expounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseases Includes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies

Management of Acute Pulmonary Embolism

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Publisher : Springer Science & Business Media
ISBN 13 : 1597452874
Total Pages : 273 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Management of Acute Pulmonary Embolism by : Stavros V. Konstantinides

Download or read book Management of Acute Pulmonary Embolism written by Stavros V. Konstantinides and published by Springer Science & Business Media. This book was released on 2007-12-31 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical volume highlights traditional, novel, and evolving aspects of the diagnosis and treatment of pulmonary embolism (PE). The contributors comprise an international team of experts. Important aspects of diagnosis, risk stratification, and differential treatment of patients with PE are presented in a concise, yet comprehensive manner. Emphasis is placed on specific issues related to PE, including pregnancy, cancer, thrombophilia, and air travel.

Severe Community Acquired Pneumonia

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792373384
Total Pages : 216 pages
Book Rating : 4.3/5 (733 download)

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Book Synopsis Severe Community Acquired Pneumonia by : Jordi Rello

Download or read book Severe Community Acquired Pneumonia written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2001-06-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.

Procalcitonin

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Publisher :
ISBN 13 : 9783837412413
Total Pages : 125 pages
Book Rating : 4.4/5 (124 download)

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Book Synopsis Procalcitonin by : Michael Meisner

Download or read book Procalcitonin written by Michael Meisner and published by . This book was released on 2010 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sepsis in Neonates and Children

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Publisher : Frontiers Media SA
ISBN 13 : 288966323X
Total Pages : 261 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Sepsis in Neonates and Children by : Luregn J. Schlapbach

Download or read book Sepsis in Neonates and Children written by Luregn J. Schlapbach and published by Frontiers Media SA. This book was released on 2021-01-04 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Evidence Base of Clinical Diagnosis

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Publisher : BMJ Books
ISBN 13 : 144430058X
Total Pages : 320 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis The Evidence Base of Clinical Diagnosis by : J. Andre Knottnerus

Download or read book The Evidence Base of Clinical Diagnosis written by J. Andre Knottnerus and published by BMJ Books. This book was released on 2009-01-26 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The Evidence Base of Clinical Diagnosis has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis. It will serve as a valuable resource for all investigators who want to embark on diagnostic research and for clinicians, practitioners and students who want to learn more about its principles and the relevant methodological options available.

The selection and use of essential in vitro diagnostics

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Author :
Publisher : World Health Organization
ISBN 13 : 9240019103
Total Pages : 380 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis The selection and use of essential in vitro diagnostics by :

Download or read book The selection and use of essential in vitro diagnostics written by and published by World Health Organization. This book was released on 2021-01-29 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: