Diabetes and Heart Failure: Basic, Translational, and Clinical Research

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Publisher : Frontiers Media SA
ISBN 13 : 283252527X
Total Pages : 110 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Diabetes and Heart Failure: Basic, Translational, and Clinical Research by : Claudio de Lucia

Download or read book Diabetes and Heart Failure: Basic, Translational, and Clinical Research written by Claudio de Lucia and published by Frontiers Media SA. This book was released on 2023-06-05 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Transforming Clinical Research in the United States

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Publisher : National Academies Press
ISBN 13 : 0309163358
Total Pages : 151 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Transforming Clinical Research in the United States by : Institute of Medicine

Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.

Cardioneurology: Basic, translational and clinical research

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Publisher : Frontiers Media SA
ISBN 13 : 2832513468
Total Pages : 223 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Cardioneurology: Basic, translational and clinical research by : Leonardo Roever

Download or read book Cardioneurology: Basic, translational and clinical research written by Leonardo Roever and published by Frontiers Media SA. This book was released on 2023-02-06 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Myocardial Preservation

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Publisher : Springer
ISBN 13 : 3319981862
Total Pages : 406 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Myocardial Preservation by : Dennis V. Cokkinos

Download or read book Myocardial Preservation written by Dennis V. Cokkinos and published by Springer. This book was released on 2019-01-28 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book reveals an integrated approach to myocardial preservation focusing on translational research and clinical applications. Chapters cover both the mechanisms of heart failure in addition to therapeutic considerations, including forms of cardiac cell death, cardiac remodelling and cardiac regeneration. Potential future research directions are also proposed, enabling the reader to gain a broad in-depth understanding of the topic. Myocardial Preservation: Translational Research and Clinical Application presents a thorough review of myocardial preservation. Its comprehensive approach provides a valuable reference for cardiology researchers and practising and trainee cardiologists seeking new insight to the topic.

The Role of Purchasers and Payers in the Clinical Research Enterprise

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Publisher : National Academies Press
ISBN 13 : 0309182905
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Role of Purchasers and Payers in the Clinical Research Enterprise by : Institute of Medicine

Download or read book The Role of Purchasers and Payers in the Clinical Research Enterprise written by Institute of Medicine and published by National Academies Press. This book was released on 2002-06-14 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a workshop organized by the Clinical Research roundtable, representatives from purchaser organizations (employers), payer organizations (health plans and insurance companies), and other stakeholder organizations (voluntary health associations, clinical researchers, research organizations, and the technology community) came together to explore: What do purchasers and payers need from the Clinical Research Enterprise? How have current efforts in clinical research met their needs? What are purchasers, payers, and other stakeholders willing to contribute to the enterprise? This book documents these discussions and summarizes what employers and insurers need from and are willing to contribute to clinical research from both a business and a national health care perspective.

The CTSA Program at NIH

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Publisher : National Academies Press
ISBN 13 : 0309284740
Total Pages : 179 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The CTSA Program at NIH by : Institute of Medicine

Download or read book The CTSA Program at NIH written by Institute of Medicine and published by National Academies Press. This book was released on 2013-10-09 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2006 the National Institutes of Health (NIH) established the Clinical and Translational Science Awards (CTSA) Program, recognizing the need for a new impetus to encourage clinical and translational research. At the time it was very difficult to translate basic and clinical research into clinical and community practice; making it difficult for individual patients and communities to receive its benefits. Since its creation the CTSA Program has expanded, with 61 sites spread across the nation's academic health centers and other institutions, hoping to provide catalysts and test beds for policies and practices that can benefit clinical and translation research organizations throughout the country. The NIH contracted with the Institute of Medicine (IOM) in 2012 to conduct a study to assess and provide recommendations on appropriateness of the CTSA Program's mission and strategic goals and whether changes were needed. The study was also address the implementation of the program by the National Center for Advancing Translational Sciences (NCATS) while exploring the CTSA's contributions in the acceleration of the development of new therapeutics. A 13-member committee was established to head this task; the committee had collective expertise in community outreach and engagement, public health and health policy, bioethics, education and training, pharmaceutical research and development, program evaluation, clinical and biomedical research, and child health research. The CTSA Program at NIH: Opportunities for Advancing Clinical and Translational Research is the result of investigations into previous program evaluations and assessments, open-session meetings and conference class, and the review of scientific literature. Overall, the committee believes that the CTSA Program is significant to the advancement of clinical and translational research through its contributions. The Program would benefit from a variety of revisions, however, to make it more efficient and effective.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2018: Oversight hearing: Federal response to the opioid crises; Oversight hearing: Advance in biomedical research; Department of Education; Department of Labor

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Publisher :
ISBN 13 :
Total Pages : 1004 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2018: Oversight hearing: Federal response to the opioid crises; Oversight hearing: Advance in biomedical research; Department of Education; Department of Labor by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2018: Oversight hearing: Federal response to the opioid crises; Oversight hearing: Advance in biomedical research; Department of Education; Department of Labor written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2017 with total page 1004 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2013

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Publisher :
ISBN 13 :
Total Pages : 1834 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2013 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2013 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2012 with total page 1834 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016

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Publisher :
ISBN 13 :
Total Pages : 1084 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2015 with total page 1084 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomarkers of Cardiometabolic Risk, Inflammation and Disease

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Publisher : Springer
ISBN 13 : 3319160184
Total Pages : 172 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Biomarkers of Cardiometabolic Risk, Inflammation and Disease by : Filipe Palavra

Download or read book Biomarkers of Cardiometabolic Risk, Inflammation and Disease written by Filipe Palavra and published by Springer. This book was released on 2015-04-11 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders. Tackling the topic in a systematic manner, the book starts with an introduction to cardiometabolic risk and its clinical relevance, comparing emergent and classical biomarkers. It then goes on to discuss cardiometabolic risk biomarkers in a range of diseases, including diabetes, ischemic stroke and neurodegenerative disorders. Biomarkers of Cardiometabolic Risk, Inflammation and Disease is aimed at doctors specializing in internal medicine, neurology, cardiology, rheumatology, nephrology or endocrinology and will also be of interest to GPs, trainee doctors and clinical and basic researchers working on cardiovascular and autoimmune disorders.

Translational Animal Models in Drug Discovery and Development

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Publisher : Bentham Science Publishers
ISBN 13 : 1608054691
Total Pages : 287 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Translational Animal Models in Drug Discovery and Development by : Xinkang Wang

Download or read book Translational Animal Models in Drug Discovery and Development written by Xinkang Wang and published by Bentham Science Publishers. This book was released on 2012-10-03 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since considerable differences in variables exist between animal models and human models (such as genetics, physiology, anatomy, gene expression, heterogeneity of disease conditions, etc.), not all the preclinical models are able to represent the pathophysiological conditions in human diseases. Therefore, partly due to the lack of congruency between animal and human disease models, several proposed therapeutic agents in the past decades have been demonstrated to be effective in preclinical models but failed in clinical studies. This e-book focuses on animal models of diseases from a translational perspective and highlights the key advantages and limitations of each model described to facilitate drug discovery and development. A unique feature of the volume is that it contains a selection of details disease models in various therapeutic niches with significant unmet medical needs, including inflammation, neurological diseases, cardiovascular and metabolic diseases, and oncology. This e-book is, therefore, of considerable value to researchers and clinicians involved in drug discovery and development as well as pathology.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2015

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Publisher :
ISBN 13 :
Total Pages : 912 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2015 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2015 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2014 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Coronary Primary Prevention Trial

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Publisher :
ISBN 13 :
Total Pages : 2 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Coronary Primary Prevention Trial by :

Download or read book Coronary Primary Prevention Trial written by and published by . This book was released on 1984 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heart Failure

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323495990
Total Pages : 121 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Heart Failure by : Longjian Liu

Download or read book Heart Failure written by Longjian Liu and published by Elsevier Health Sciences. This book was released on 2017-09-14 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the many key facets of heart failure research with this concise, practical resource by Dr. Longjian Liu. This easy-to-read reference focuses on the incidence, distribution, and possible control of this significant clinical and public health problem which is often associated with higher mortality and morbidity, as well as increased healthcare expenditures. This practical resource brings you up to date with what's new in the field and how it can benefit your patients. - Features a wealth of information on epidemiology and research methods related to heart failure. - Discusses pathophysiology and risk profile of heart failure, research and design, biostatistical basis of inference in heart failure study, advanced biostatistics and epidemiology applied in heart failure study, and precision medicine and areas of future research. - Consolidates today's available information and guidance in this timely area into one convenient resource.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011

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Publisher :
ISBN 13 :
Total Pages : 1830 pages
Book Rating : 4.:/5 (53 download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011 by : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 2010 with total page 1830 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011, Part 2A, 111-2 Hearings

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Publisher :
ISBN 13 :
Total Pages : 1822 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011, Part 2A, 111-2 Hearings by :

Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2011, Part 2A, 111-2 Hearings written by and published by . This book was released on 2010 with total page 1822 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diabetes and Hypertension

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Publisher : Springer Science & Business Media
ISBN 13 : 1603273573
Total Pages : 196 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Diabetes and Hypertension by : Samy I. McFarlane

Download or read book Diabetes and Hypertension written by Samy I. McFarlane and published by Springer Science & Business Media. This book was released on 2012-10-19 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.