Development Of Screen Printed Impedance Biocensor For Characterization Of Cancer Cells

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Development of Screen-printed Impedance Biocensor for Characterization of Cancer Cells

Author : Ahmad Fairuzabadi bin Mohd Mansor
Publisher :
ISBN 13 :
Total Pages : 198 pages
Book Rating : 4.:/5 (973 download)

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Book Synopsis Development of Screen-printed Impedance Biocensor for Characterization of Cancer Cells by : Ahmad Fairuzabadi bin Mohd Mansor

Download or read book Development of Screen-printed Impedance Biocensor for Characterization of Cancer Cells written by Ahmad Fairuzabadi bin Mohd Mansor and published by . This book was released on 2016 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electric Cell-Substrate Impedance Sensing (ECIS) is currently gaining widespread application in biomedical field such as cell monitoring. The ability to monitor growth and death of mammalian cells has made this technique more and more popular in drug discovery. Currently chemotherapy treatment subject patients to trial and error therapy, resulting in unoptimized dosage and unnecessary pain for patients. Optimal treatment effectiveness can only be accomplished when the chemotherapy dosage is individualized to each patient. In this study, a silver/silver chloride screen-printed impedance biosensor on glass was developed to characterize A549 lung cancer cell growth in the presence of collagen I, Bovine as substrate coating. The sensor comprise of Interdigital Electrodes Structures (IDEs) with variable spacing. The sensor's optimum spacing between electrodes has been simulated using COMSOL Multiphysics. The sensor was fabricated and incorporated with a culture well made of polydimethylsiloxane (PDMS). A549 cells were cultured in the chambers and impedance measurements were taken at 12 hours intervals for 120 hours. Cell Index (CI) were calculated from the impedance measurement and plotted against time together with the growth profile of the cells using conventional method. A549 cells were also treated with chemotherapy drug; Paclitaxel and its response were monitored over 5 days. Experimental results using biosensor show a similar trend with conventional growth profile of cells in T-flask. Significant reduction in Cell Index (CI) was observed after exposure to Paclitaxel indicating the reliability of the impedance biosensor. Lower spacing between the electrodes has been found to be more sensitive, producing higher Cell Index during cell growth. This work indicates that silver/silver chloride screen printed sensor offers a low cost solution for personalized sensors as it provides a rapid, real time, continuous, reliable method for chemotherapy drug screening.

Electrochemical Biosensors

Author : Serge Cosnier
Publisher : CRC Press
ISBN 13 : 9814411477
Total Pages : 405 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Electrochemical Biosensors by : Serge Cosnier

Download or read book Electrochemical Biosensors written by Serge Cosnier and published by CRC Press. This book was released on 2015-01-26 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy

International Conference for Innovation in Biomedical Engineering and Life Sciences

Author : Fatimah Ibrahim
Publisher : Springer
ISBN 13 : 9811002665
Total Pages : 340 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis International Conference for Innovation in Biomedical Engineering and Life Sciences by : Fatimah Ibrahim

Download or read book International Conference for Innovation in Biomedical Engineering and Life Sciences written by Fatimah Ibrahim and published by Springer. This book was released on 2015-11-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volumes presents the proceedings of ICIBEL 2015, organized by the Centre for Innovation in Medical Engineering (CIME) under Innovative Technology Research Cluster, University of Malaya. It was held in Kuala Lumpur, Malaysia, from 6-8 December 2015. The ICIBEL 2015 conference promotes the latest researches and developments related to the integration of the Engineering technology in medical fields and life sciences. This includes the latest innovations, research trends and concerns, challenges and adopted solution in the field of medical engineering and life sciences.

Development of a System for Fast Identification and Characterization of Biological Cells

Author : Viviane Silva Teixeira
Publisher :
ISBN 13 : 9783832557515
Total Pages : 0 pages
Book Rating : 4.5/5 (575 download)

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Book Synopsis Development of a System for Fast Identification and Characterization of Biological Cells by : Viviane Silva Teixeira

Download or read book Development of a System for Fast Identification and Characterization of Biological Cells written by Viviane Silva Teixeira and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioelectronics

Author : Anuj Kumar
Publisher : CRC Press
ISBN 13 : 1000789470
Total Pages : 406 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Bioelectronics by : Anuj Kumar

Download or read book Bioelectronics written by Anuj Kumar and published by CRC Press. This book was released on 2022-12-08 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioelectronics is emerging as a new area of research where electronics can selectively detect, record, and monitor physiological signals. This is a rapidly expanding area of medical research, that relies heavily on multidisciplinary technology development and cutting-edge research in chemical, biological, engineering, and physical science. This book provides extensive information on the (i) fundamental concepts of bioelectronics, (ii) materials for the developments of bioelectronics such as implantable electronics, self-powered devices, bioelectronic sensors, flexible bioelectronics, etc, and (iii) an overview of the trends and gathering of the latest bioelectronic progress. This book will broaden our knowledge about newer technologies and processes used in bioelectronics.

Label Free Biosensor Development and Ionic Liquid-electrode Interface Characterization for Sensor Application

Author :
Publisher :
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.:/5 (864 download)

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Book Synopsis Label Free Biosensor Development and Ionic Liquid-electrode Interface Characterization for Sensor Application by :

Download or read book Label Free Biosensor Development and Ionic Liquid-electrode Interface Characterization for Sensor Application written by and published by . This book was released on 2013 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work, several novel label-free biosensors have been developed for protein, bacteria detections and immunoassays based on the use of QCM, which is efficient and sensitive. Firstly, mannosyl functionalized polyaniline was used as a platform to anchor carbohydrates onto QCM electrode and further as a nonlabeled biosensor for carbohydrate/lectin recognition and bacteria detection. Secondly, the feasibility of integration of QCM and EIS, a potential powerful tool for miniaturized nonlabeled biosensor development, was evaluated by using rabbit IgG/ anti-rabbit IgG as a model system. Thirdly, a nonlabeled biosensor using CD20 antigen on cancerous B cells as sensing element was developed to study cell surface antigen and antibody interactions, which is significant for facilitating the comprehension of mechanisms of resistance to antibody based therapy. Finally, fundamental study of ionic liquid-electrode interface was carried out with preliminary results presented and an ionic liquid based amperometric oxygen sensor operating in harsh environment was developed.

Optimization of Bio-Impedance Sensor for Enhanced Detection and Characterization of Adherent Cells

Author : Dorielle T. Price
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (811 download)

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Book Synopsis Optimization of Bio-Impedance Sensor for Enhanced Detection and Characterization of Adherent Cells by : Dorielle T. Price

Download or read book Optimization of Bio-Impedance Sensor for Enhanced Detection and Characterization of Adherent Cells written by Dorielle T. Price and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This research focuses on the detection and characterization of cells using impedance-based techniques to understand the behavior and response of cells to internal/environmental changes. In combination with impedimetric sensing techniques, the biosensors in this work allow rapid, label-free, quantitative measurements and are very sensitive to changes in environment and cell morphology. The biosensor design and measurement setup is optimized to detect and differentiate cancer cells and healthy (normal) cells. The outcome of this work will provide a foundation for enhanced 3-dimensional tumor analysis and characterization; thus creating an avenue for earlier cancer detection and reduced healthcare costs. The magnitude of cancer-related deaths is a result of late-diagnosis and the fact that cancer is challenging to treat, due to the non-uniform nature of the tumor. In order to characterize and treat individual cells based on their malignant potential, it is important to have a measurement technique with enhanced spatial resolution and increased sensitivity. This requires the study of individual or small groups of cells that make up the entire tissue mass. The overall objective of this research is to optimize a microelectrode biosensor and obtain statistically relevant data from a cell culture using an independent multi-electrode design. This would provide a means to explore the feasibility of electrically characterizing cells with greater accuracy and enhanced sensitivity.

New Developments in Nanosensors for Pharmaceutical Analysis

Author : Sibel A. Ozkan
Publisher : Academic Press
ISBN 13 : 012816378X
Total Pages : 430 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis New Developments in Nanosensors for Pharmaceutical Analysis by : Sibel A. Ozkan

Download or read book New Developments in Nanosensors for Pharmaceutical Analysis written by Sibel A. Ozkan and published by Academic Press. This book was released on 2019-05-22 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Developments for Nanosensors in Pharmaceutical Analysis presents an overview of developments in nanosensor usage in pharmaceutical analysis, thereby helping pharmaceutical companies attain reliable, precise, and accurate analysis of pharmaceuticals. This book presents very simple, precise, sensitive, selective, fast, and relatively inexpensive methods for pre-treatment, prior to analysis. These methods may be considered for further application in clinical studies and assays. The book includes the manufacturing of sensors for pharmaceutical analysis at nano- or smaller scales, and gives simple and relatable designs for the fabrication of sensors. Twelve chapters cover an introduction to the topic, immobilization techniques, mechanism effect of nanomaterials on structure, optical nanosensors for pharmaceutical detection, chemical nanosensors in pharmaceutical analysis, noble metal nanoparticles in electrochemical analysis of drugs, photo-electrochemical nanosensors for drug analysis, molecularly imprinted polymer based nanosensors for pharmaceutical analysis, nanomaterials for drug delivery systems, nanomaterials enriched nucleic acid-based biosensors, nanosensors in biomarker detection, and nanomaterials-based enzyme biosensors for electrochemical applications. Presents nanosensor types, synthesis, immobilizations and applications in different fields Gives simple repeatable designs for the fabrication of sensors for pharmaceutical analysis Details how to carry out sensitive analysis of pharmaceuticals using nanosensors Describes how to synthesize and immobilize nanosensors, and how nanosensors can be applied in drug assay Proposes innovative ways to optimize pharmaceutical processes with nanosensors

Biosensors for Health, Environment and Biosecurity

Author : Pier Andrea Serra
Publisher : BoD – Books on Demand
ISBN 13 : 9533074434
Total Pages : 554 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Biosensors for Health, Environment and Biosecurity by : Pier Andrea Serra

Download or read book Biosensors for Health, Environment and Biosecurity written by Pier Andrea Serra and published by BoD – Books on Demand. This book was released on 2011-07-19 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biosensor is a detecting device that combines a transducer with a biologically sensitive and selective component. Biosensors can measure compounds present in the environment, chemical processes, food and human body at low cost if compared with traditional analytical techniques. This book covers a wide range of aspects and issues related to biosensor technology, bringing together researchers from 16 different countries. The book consists of 24 chapters written by 76 authors and divided in three sections: Biosensors Technology and Materials, Biosensors for Health and Biosensors for Environment and Biosecurity.

Advances in Clinical Chemistry

Author :
Publisher : Academic Press
ISBN 13 : 0128208007
Total Pages : 308 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Advances in Clinical Chemistry by :

Download or read book Advances in Clinical Chemistry written by and published by Academic Press. This book was released on 2019-10-24 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Clinical Chemistry, Volume 93, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New chapters in this release include Lectin biosensors in cancer glycan biomarker detection, Cytokines in heart failure, Recent advances in the determination of insulins from biological fluids, Biomarkers in aggression, Evaluation of analytical performance of immunoassay methods for cTnI and cTnT: From theory to practice, Periodontal disease: From the lenses of light microscopy to the specs of proteomics and next generation sequencing, and more. Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science Authored by world renowned clinical laboratory scientists, physicians and research scientists Presents the international benchmark for novel analytical approaches in the clinical laboratory

Proceedings of 4th International Conference on Electrochemistry 2018

Author : ConferenceSeries
Publisher : ConferenceSeries
ISBN 13 :
Total Pages : 133 pages
Book Rating : 4./5 ( download)

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Book Synopsis Proceedings of 4th International Conference on Electrochemistry 2018 by : ConferenceSeries

Download or read book Proceedings of 4th International Conference on Electrochemistry 2018 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 11-12, 2018 Rome, Italy Key Topics Theoretical and Computational Electrochemistry, Physical and Analytical Electrochemistry, Photoelectrochemistry, Electrochemical Energy, Sensors, Organic and Bioelectrochemistry, Batteries and Energy Storage, Corrosion Science and Technology, Electronic Materials and Processing, Carbon Nanostructures, Dielectric Science and Materials, Electrochemical Electroless Deposition, Electrochemical Water Treatment, Electrochemical Surface Science, Electrochemical Engineering, Environmental Electrochemistry, Applied Electrochemistry, Inorganic Electrochemistry, Market Surveillance of Electrochemistry,

Immunosensors

Author : Minhaz Uddin Ahmed
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014375
Total Pages : 386 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Immunosensors by : Minhaz Uddin Ahmed

Download or read book Immunosensors written by Minhaz Uddin Ahmed and published by Royal Society of Chemistry. This book was released on 2019-08-28 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunosensors are widely used and are particularly important for fast diagnosis of diseases in remote environments as well as point-of-care devices. In this book, expert scientists are covering a selection of high quality representative examples from the past five years explaining how this area has developed. It is a compilation of recent advances in several areas of immunosensors for multiple target analysis using laboratory based or point-of-care set-up, for example graphene-, ISFET- and nanostructure-based immunosensors, electrochemical magneto immunosensors and nanoimprinted immunosensors. Filling a gap in the literature, it showcases the multidisciplinary, innovative developments in this highly important area and provides pointers towards commercialisation. Delivering a single, comprehensive work, it appeals to graduate students and professional researchers across academia and industry.

Biomaterials-Based Sensors

Author : Prasun Kumar
Publisher : Springer Nature
ISBN 13 : 9811985014
Total Pages : 416 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Biomaterials-Based Sensors by : Prasun Kumar

Download or read book Biomaterials-Based Sensors written by Prasun Kumar and published by Springer Nature. This book was released on 2023-03-01 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recent technological advancement usage of unique nanomaterials and bio-based composite materials as sensors has been greatly improved. Biopolymers and bio-based composite materials have especially been exploited due to their unique physical, optical, electrochemical, and biocompatible properties. In this book, experts and researchers in various sensor technology areas discuss the basics of biosensors, the methods used to synthesize different biomaterials, and the characterization and functionalization of these biomaterials. Processes for the self-assembly of biomaterials and the fabrication of biomaterials onto transducers are clearly explained. It also outlines the current status in the field and the utility of such bio-based sensors for medical diagnostics, food safety, industrial, and environmental monitoring. Besides pressure and temperature sensing applications, other applications include detecting gases, chemicals, biomolecules, body fluids, bacteria, and viruses. The book is well illustrated, and the presentation is concise and systematic throughout. Biomaterials-Based Sensors will be an ideal source of up-to-date information for all engaged in their research, design, and use.

In-situ Characterization Techniques for Nanomaterials

Author : Challa S.S.R. Kumar
Publisher : Springer
ISBN 13 : 3662563223
Total Pages : 458 pages
Book Rating : 4.6/5 (625 download)

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Book Synopsis In-situ Characterization Techniques for Nanomaterials by : Challa S.S.R. Kumar

Download or read book In-situ Characterization Techniques for Nanomaterials written by Challa S.S.R. Kumar and published by Springer. This book was released on 2018-04-17 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seventh volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about In-situ Characterization Techniques for Nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Biosensors for Medical Applications

Author : Séamus Higson
Publisher : Elsevier
ISBN 13 : 0857097180
Total Pages : 356 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Biosensors for Medical Applications by : Séamus Higson

Download or read book Biosensors for Medical Applications written by Séamus Higson and published by Elsevier. This book was released on 2012-08-21 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical sensors are an essential tool in the detection and monitoring of a wide range of medical conditions from cancer to Parkinson’s disease. Biosensors for medical applications provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications. Part one focuses on key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors. Impedence interrogated affinity biosensors for medical applications and practical applications of enzyme biosensors are explored, before part two goes on to review specific medical applications. Biosensors for DNA and RNA detection and characterization, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors are investigated, along with biosensors for drug testing and discovery, non-invasive measurements, and wearable biosensors for medical applications. With its distinguished editor and international team of expert contributors, Biosensors for medical applications is an essential guide for all those involved in the research, design, production and use of medical biosensors. Provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications Examines key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors Reviews biosensors for DNA and RNA detection and characterisation, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors

Nanobiosensors

Author : Alexandru Grumezescu
Publisher : Academic Press
ISBN 13 : 0128043725
Total Pages : 928 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanobiosensors by : Alexandru Grumezescu

Download or read book Nanobiosensors written by Alexandru Grumezescu and published by Academic Press. This book was released on 2016-09-28 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed. Includes the most up-to-date information on nanoparticles based biosensors and quantum dots for biological detection Provides application methods and techniques for research analysis for bacteriological detection and food testing Presents studies using analytical tools to improve food safety and quality analysis

Functionalized Nanomaterials for Biosensing and Bioelectronics Applications

Author : Sudheesh K. Shukla
Publisher : Woodhead Publishing
ISBN 13 : 0128238437
Total Pages : 378 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Functionalized Nanomaterials for Biosensing and Bioelectronics Applications by : Sudheesh K. Shukla

Download or read book Functionalized Nanomaterials for Biosensing and Bioelectronics Applications written by Sudheesh K. Shukla and published by Woodhead Publishing. This book was released on 2024-06-28 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry and related fields. Introduces the most common functionalized nanomaterials and their morphologies, properties, and mechanisms for sensing applications Reviews functionalization and fabrication methods and techniques for the integration of one- and two-dimensional materials for sensing applications Addresses the most relevant applications of functionalized nanomaterials for biosensing and bioelectronics applications