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Development Of Gas Phase Ion Mobility Separation Methods Combined With Mass Spectrometry For The Analysis Of Biological Mixtures
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Author :Radislav A. Potyrailo Publisher :Springer Science & Business Media ISBN 13 :1441989897 Total Pages :642 pages Book Rating :4.4/5 (419 download)
Book Synopsis High-Throughput Analysis by : Radislav A. Potyrailo
Download or read book High-Throughput Analysis written by Radislav A. Potyrailo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, edited by Potyrailo and Amis, addresses a new paradigm-shifting approach in the search for new materials-Combinatorial Materials Science. One way to consider such an approach is to imagine an adventurous chef who decides to look for new entrees by cooking food ingredients in many pots using different combinations in every pot, and boil ing, steaming, or frying them in various ways. Although most of the pots will not have the tastiest food ever devised, some recipes will taste intriguing, and some eventually will lead to a discovery of a new fascinating cuisine. Of course, having a skilled chef design the com binatorial formulation will certainly be helpful in ensuring a successful outcome. Similar to food, each engineering material is a complex product of its chemical composition, structure, and processing. Generally, each of these components matters---change one and you get another material. Most of these "new" materials will be less good than ones we use now since existing materials have been refined with the extensive work of scientists and engi neers. At the same time if one prepares diverse materials like our adventurous chef, chang ing material composition, processing conditions and time, etc. , some of these materials will be superior to existing ones and a few might represent breakout technology.
Book Synopsis Plasma Chromatography by : T.W. Carr
Download or read book Plasma Chromatography written by T.W. Carr and published by Springer. This book was released on 1984-03-31 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2007 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Differential Ion Mobility Spectrometry by : Alexandre A. Shvartsburg
Download or read book Differential Ion Mobility Spectrometry written by Alexandre A. Shvartsburg and published by CRC Press. This book was released on 2008-12-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, scientific and engineering interests have been shifting from conventional ion mobility spectrometry (IMS) to field asymmetric waveform ion mobility spectrometry (FAIMS). Differential Ion Mobility Spectrometry: Nonlinear Ion Transport and Fundamentals of FAIMS explores this new analytical technology that separates and characterizes ions by the difference between their mobility in gases at high and low electric fields. It also covers the novel topics of higher-order differential IMS and IMS with alignment of dipole direction. The book relates the fundamentals of FAIMS and other nonlinear IMS methods to the physics of gas-phase ion transport. It begins with the basics of ion diffusion and mobility in gases, covering the main attributes of conventional IMS that are relevant to all IMS approaches. Building on this foundation, the author reviews diverse high-field transport phenomena that underlie differential IMS. He discusses the conceptual implementation and first-principles optimization of FAIMS as a filtering technique, emphasizing the dependence of FAIMS performance metrics on instrumental parameters and properties of ion species. He also explores ion reactions in FAIMS caused by field heating and the effects of inhomogeneous electric field in curved FAIMS gaps. Written by an accomplished scientist in the field, this state-of-the-art book supplies the foundation to understand the new technology of nonlinear IMS methods.
Book Synopsis Ion Mobility Spectrometry - Mass Spectrometry by : Charles L. Wilkins
Download or read book Ion Mobility Spectrometry - Mass Spectrometry written by Charles L. Wilkins and published by CRC Press. This book was released on 2010-12-14 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analytical power of ion mobility spectrometry-mass spectrometry (IMS-MS) instruments is poised to advance this technology from research to analytical laboratories. Exploring these developments at this critical juncture, Ion Mobility Spectrometry-Mass Spectrometry: Theory and Applications covers the tools, techniques, and applications involved w
Book Synopsis Ion Mobility-Mass Spectrometry by : Frank Sobott
Download or read book Ion Mobility-Mass Spectrometry written by Frank Sobott and published by Royal Society of Chemistry. This book was released on 2021-11-26 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and will help the end users understand the practicalities of using different instruments for different ion mobility purposes.
Book Synopsis Ion Mobility-Mass Spectrometry by : Alison E Ashcroft
Download or read book Ion Mobility-Mass Spectrometry written by Alison E Ashcroft and published by Royal Society of Chemistry. This book was released on 2021-11-11 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.
Book Synopsis Chiral Analysis by : Kenneth W. Busch
Download or read book Chiral Analysis written by Kenneth W. Busch and published by Elsevier. This book was released on 2011-10-13 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Analysis covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals. The target audience is scientific professionals with an undergraduate background in chemistry or a related discipline, specifically organic chemists, researchers in drug discovery, pharmaceutical researchers involved with process analysis or combinatorial libraries, and graduate students in chemistry. Chapters have been written with the nonspecialist in mind so as to be self-contained.* Broad coverage - spectroscopic and separation methods covered in a single volume* Up-to-date and detailed review of the various techniques available and/or under development in this field* Contributions from leading experts in the field
Book Synopsis Methodologies for Metabolomics by : Norbert W. Lutz
Download or read book Methodologies for Metabolomics written by Norbert W. Lutz and published by Cambridge University Press. This book was released on 2013-01-21 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.
Book Synopsis Ion Mobility Spectrometry by : G.A. Eiceman
Download or read book Ion Mobility Spectrometry written by G.A. Eiceman and published by CRC Press. This book was released on 2005-06-23 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key Developments for Faster, More Precise Detection Capabilities Driven by the demand for the rapid and advanced detection of explosives, chemical and biological warfare agents, and narcotics, ion mobility spectrometry (IMS) undergone significant refinements in technology, computational capabilities, and understanding of the principles of gas phase
Book Synopsis Handbook of Methods and Instrumentation in Separation Science by :
Download or read book Handbook of Methods and Instrumentation in Separation Science written by and published by Academic Press. This book was released on 2009-11-11 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. - One-stop source for information on separation methods - General overviews for quick orientation - Ease of use for finding results fast - Expert coverage of major separation methods - Coverage of techniques for all sizes of samples, pico-level to kilo-level
Book Synopsis American Doctoral Dissertations by :
Download or read book American Doctoral Dissertations written by and published by . This book was released on 2001 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pharmacoproteomics by : Seth Kwabena Amponsah
Download or read book Pharmacoproteomics written by Seth Kwabena Amponsah and published by Springer Nature. This book was released on 2024 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of pharmacoproteomics and its clinical applications, as well as the latest information on drug mechanisms at the proteome level, the relationship between proteomics and toxicity or resistance, and how proteomics aid in discovery of new drug targets. The book also highlights recent advances in analytical methods, analysis, and interpretation of pharmacoproteomic data. Pharmacoproteomics: Recent Trends and Applications is an ideal book for those working in pharmaceutical industries, as well as scientists, health care professionals, and researchers who work in the field of genomics, pharmacology, pharmacokinetics, toxicology, and pharmaceutical chemistry.
Book Synopsis Carbohydrate Chemistry: State Of The Art And Challenges For Drug Development - An Overview On Structure, Biological Roles, Synthetic Methods And Application As Therapeutics by : Laura Cipolla
Download or read book Carbohydrate Chemistry: State Of The Art And Challenges For Drug Development - An Overview On Structure, Biological Roles, Synthetic Methods And Application As Therapeutics written by Laura Cipolla and published by World Scientific. This book was released on 2015-07-23 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structural complexity and the synthetic challenges facing glycans have historically hampered efforts to study their multifaceted roles and the application of carbohydrates in drug development. However, in very recent years, new synthetic techniques flanked by the growing knowledge about carbohydrate involvement in physiological and pathological states has spurred renewed interest in the chemistry, biology and therapeutic potentialities of carbohydrates. This book offers an overview of key aspects of carbohydrate biology and chemistry that are fundamental for the design of novel therapeutics. The four-part structure of this book introduces these essential components to life, starting from their structure and biological roles and covering analytical methods and synthesis which pave the way for the development of a wide range of therapeutic applications.Leading experts from around the world are brought together to offer their recent research with the ultimate aim of enlightening the reader on the complex yet exciting field of carbohydrate chemistry. Academic and industrial researchers in structural biology, drug discovery and carbohydrate chemistry will find this book an essential guide to the latest research and future potential of medicinal chemistry.
Book Synopsis Biomolecular and Bioanalytical Techniques by : Vasudevan Ramesh
Download or read book Biomolecular and Bioanalytical Techniques written by Vasudevan Ramesh and published by John Wiley & Sons. This book was released on 2019-06-10 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to biomolecular and bioanalytical techniques and their applications Biomolecular and Bioanalytical Techniques offers an introduction to, and a basic understanding of, a wide range of biophysical techniques. The text takes an interdisciplinary approach with contributions from a panel of distinguished experts. With a focus on research, the text comprehensively covers a broad selection of topics drawn from contemporary research in the fields of chemistry and biology. Each of the internationally reputed authors has contributed a single chapter on a specific technique. The chapters cover the specific technique’s background, theory, principles, technique, methodology, protocol and applications. The text explores the use of a variety of analytical tools to characterise biological samples. The contributors explain how to identify and quantify biochemically important molecules, including small molecules as well as biological macromolecules such as enzymes, antibodies, proteins, peptides and nucleic acids. This book is filled with essential knowledge and explores the skills needed to carry out the research and development roles in academic and industrial laboratories. A technique-focused book that bridges the gap between an introductory text and a book on advanced research methods Provides the necessary background and skills needed to advance the research methods Features a structured approach within each chapter Demonstrates an interdisciplinary approach that serves to develop independent thinking Written for students in chemistry, biological, medical, pharmaceutical, forensic and biophysical sciences, Biomolecular and Bioanalytical Techniques is an in-depth review of the most current biomolecular and bioanalytical techniques in the field.
Book Synopsis Manipulation and Characterization of Electrosprayed Ions Under Ambient Conditions by : Zane Baird
Download or read book Manipulation and Characterization of Electrosprayed Ions Under Ambient Conditions written by Zane Baird and published by Springer. This book was released on 2016-12-08 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis addresses the evolving field of measurement science, specifically that of mass spectrometry (MS) and ion mobility spectrometry (IMS) based techniques. It focuses on the design, construction and implementation of low-cost, easy-to-manufacture measurement tools that are used in modern settings such as airport security screening. Advances in these technologies often involve minimal performance enhancement at ever-increasing cost, which in turn limits accessibility to versatile measurement tools. This problem is addressed using desktop 3D printers along with widely available materials for the production of novel ion lenses and an IMS instrument with a performance comparable to that of many commercial systems. Baird ́s findings are a source of inspiration for scientists exploring this emerging field./div
Author :Society of Photo-optical Instrumentation Engineers Publisher :SPIE-International Society for Optical Engineering ISBN 13 : Total Pages :260 pages Book Rating :4.3/5 (91 download)
Book Synopsis Advances in Nucleic Acid and Protein Analyses, Manipulation, and Sequencing by : Society of Photo-optical Instrumentation Engineers
Download or read book Advances in Nucleic Acid and Protein Analyses, Manipulation, and Sequencing written by Society of Photo-optical Instrumentation Engineers and published by SPIE-International Society for Optical Engineering. This book was released on 2000 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: