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Development Of A Novel Matrix Assisted Laser Desorption
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Book Synopsis Development and Application of Novel Matrices Under Matrix-assisted Laser Desorption/ionization Time-of-flight (MALDI-TOF) Mass Spectrometry Conditions by : Bharat R. Mankani
Download or read book Development and Application of Novel Matrices Under Matrix-assisted Laser Desorption/ionization Time-of-flight (MALDI-TOF) Mass Spectrometry Conditions written by Bharat R. Mankani and published by . This book was released on 2010 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of a Novel Matrix Assisted Laser Desorption by : Kandalama KD Priyasantha
Download or read book Development of a Novel Matrix Assisted Laser Desorption written by Kandalama KD Priyasantha and published by . This book was released on 2015 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Matrix Assisted Laser Desorption / Ionization (MALDI) Mass Spectrometry (MS) has emerged as an important tool in the field of proteomics mainly because it is simple, quick and efficient. The identification and quantitation of biomarkers, protein targets for drugs, and metabolites are some of the important fields in proteomics research. Although MALDI MS is an important tool in proteomics research there are drawbacks of the technique that need further development in order for the approach to be used in clinical laboratories. One major limitation of MALDI MS is the generally poor reproducibility of ion signal intensities, which negatively impacts the quantitation of peptides and protein by MALDI MS. A considerable amount of research has been performed in an effort to improve the ion signal reproducibility in MALDI MS. However, many of the approaches developed have introduced specific drawbacks with respect to the traditional dried-droplet sample preparation technique, negating many of the advantages of the MALDI MS approach. This project has focused on the development of a novel approach to quantify peptides by MALDI MS while preserving traditional known advantages of the technique. The studies performed show that an approach in which the ion signal base widths are manipulated to match that of a reference ion signal, through adjustments in desorption laser intensity, leads to much higher reproducibility in the integrated ion signal intensities. A standard curve acquired using the constant ion signal base width approach showed lower average RSDs ( 10.00% vs. 39.00%) and improved R 2 values (> 0.9600 vs.
Book Synopsis The Development of a Matrix-assisted Laser Desorption by : Christopher Paul Myatt
Download or read book The Development of a Matrix-assisted Laser Desorption written by Christopher Paul Myatt and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of Novel Interfaces for Combining Liquid Chromatography with Matrix-assisted Laser Desorption Ionization Mass Spectrometry by : Jason Bryce Young
Download or read book Development of Novel Interfaces for Combining Liquid Chromatography with Matrix-assisted Laser Desorption Ionization Mass Spectrometry written by Jason Bryce Young and published by . This book was released on 2009 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Matrix-assisted Laser Desorption Ionization Mass Spectrometry by : Jonathon Kevin Gooden
Download or read book Matrix-assisted Laser Desorption Ionization Mass Spectrometry written by Jonathon Kevin Gooden and published by . This book was released on 2005 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of Matrix-assisted Laser Desorption Ionization Mass Spectrometry for Biopolymer Analysis by :
Download or read book Development of Matrix-assisted Laser Desorption Ionization Mass Spectrometry for Biopolymer Analysis written by and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of Solid Phase Microextraction Coupled to Matrix Assisted Laser Desorption/ionization by : Hui Tong
Download or read book Development of Solid Phase Microextraction Coupled to Matrix Assisted Laser Desorption/ionization written by Hui Tong and published by . This book was released on 2002 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Yuqin Dai Publisher :National Library of Canada = Bibliothèque nationale du Canada ISBN 13 :9780612395190 Total Pages :332 pages Book Rating :4.3/5 (951 download)
Book Synopsis Development of Matrix-assisted Laser Desorption Ionization Mass Spectrometry for Biopolymer Analysis [microform] by : Yuqin Dai
Download or read book Development of Matrix-assisted Laser Desorption Ionization Mass Spectrometry for Biopolymer Analysis [microform] written by Yuqin Dai and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Developing New Matrices for Matrix-assisted Laser Desorption by : Nicholas Carl Charnley
Download or read book Developing New Matrices for Matrix-assisted Laser Desorption written by Nicholas Carl Charnley and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Insights & Updates on The Molecular Epidemiology and Antimicrobial Resistance of MRSA in Humans in the Whole-Genome Sequencing Era by : David Coleman
Download or read book New Insights & Updates on The Molecular Epidemiology and Antimicrobial Resistance of MRSA in Humans in the Whole-Genome Sequencing Era written by David Coleman and published by Frontiers Media SA. This book was released on 2019-07-11 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methicillin-resistant Staphylococcus aureus (MRSA) have been a major cause of healthcare-associated (HA) infection globally for several decades. During this time many distinct clones have emerged independently around the world, some of which have achieved pandemic status. More recently, community-associated (CA) and livestock-associated MRSA clones have also emerged, some of which have become established in hospitals and other healthcare facilities, and sometimes have displaced previously predominant HA clones. Importantly, MRSA can frequently exhibit resistance to a wide range of clinically relevant antibiotics, which limits treatment options and complicates patient management and outcomes. Investigating routes of transmission and spread of MRSA in healthcare facilities have conventionally been undertaken by combining available epidemiological information with data from DNA-based typing systems such as pulse-field gel electrophoresis typing, spa typing, multilocus sequence typing, and more recently, DNA microarray profiling. However, these approaches can frequently lack the discriminatory ability to differentiate between MRSA isolates in healthcare environments where a relatively small number of clones may predominate. The advent of high-throughput whole genome sequencing (WGS) over the last decade with the development of affordable, easy-to-use benchtop DNA sequencing platforms, associated sequencing chemistry and bioinformatics tools, has revolutionized studies of MRSA epidemiology and evolution. The significantly enhanced discriminatory power and resolution afforded by WGS has also provided hitherto unimaginable insights into the origins, emergence and factors that drive the evolution of specific MRSA clones. Furthermore, WGS has highlighted the very significant contributions of mobile genetic elements (MGEs) encoding virulence factors and resistance genes from coagulase-negative staphylococcal (CoNS) species to the emergence and evolution of MRSA. This Research Topic brings together a collection of original research articles and up-to-date reviews that highlight the significant impact WGS is having on our understanding of the epidemiology and routes of transmission of HA- and CA-MRSA in humans and the phylogenetics and evolution of specific MRSA clones. The Research Topic also highlights the impact that WGS is having on our understanding of antimicrobial resistance in MRSA by acquisition of MGEs and the role of specific CoNS species in the origins and evolution of particular MGEs that can promote the survival of MRSA following acquisition. Finally, the Research Topic highlights the immense potential impact of WGS technology in surveillance, rapid pathogen detection, identification of virulence factor profiles and antibiotic resistance genotypes, possibly from clinical samples directly.
Book Synopsis The Development of Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry and Its Application to the Study of Polymers and Biopolymers by : Sajid Bashir
Download or read book The Development of Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry and Its Application to the Study of Polymers and Biopolymers written by Sajid Bashir and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of an Atmospheric Pressure Matrix-assisted Laser Desorption by : Claudie Kate Black
Download or read book Development of an Atmospheric Pressure Matrix-assisted Laser Desorption written by Claudie Kate Black and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacology written by Luca Gallelli and published by IntechOpen. This book was released on 2012-03-14 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of pharmacology travels together to history of scientific method and the latest frontiers of pharmacology open a new world in the search of drugs. New technologies and continuing progress in the field of pharmacology has also changed radically the way of designing a new drug. In fact, modern drug discovery is based on deep knowledge of the disease and of both cellular and molecular mechanisms involved in its development. The purpose of this book was to give a new idea from the beginning of the pharmacology, starting from pharmacodynamic and reaching the new field of pharmacogenetic and ethnopharmacology.
Book Synopsis Genetic Analysis by Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry by : Timothy J. Griffin
Download or read book Genetic Analysis by Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry written by Timothy J. Griffin and published by . This book was released on 1999 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of Matrix-assisted Ultraviolet Laser Desorption/ionization Mass Spectrometry for the Structural Analysis of Glycoproteins by : Marc Roger Chevrier
Download or read book Development of Matrix-assisted Ultraviolet Laser Desorption/ionization Mass Spectrometry for the Structural Analysis of Glycoproteins written by Marc Roger Chevrier and published by . This book was released on 1993 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development and Application of Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution Studies by : Mark Thomas Bokhart
Download or read book Development and Application of Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution Studies written by Mark Thomas Bokhart and published by . This book was released on 2017 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of a Matrix-assisted Laser Desorption/ionisation Mass Spectrometric Platform for Detecting Non-covalent Interactions Between Molecules. Partial Characterisation of Bioactive Components from Bovine Colostrum and Milk on Immune Response by : Ann Louise Worsøe Jørgensen
Download or read book Development of a Matrix-assisted Laser Desorption/ionisation Mass Spectrometric Platform for Detecting Non-covalent Interactions Between Molecules. Partial Characterisation of Bioactive Components from Bovine Colostrum and Milk on Immune Response written by Ann Louise Worsøe Jørgensen and published by . This book was released on 2009 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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