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Author : Helga Kolb
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (53 download)
Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nai-Wen Tien
Publisher :
ISBN 13 :
Total Pages : 103 pages
Book Rating : 4.:/5 (14 download)
Download or read book Development and Function of Retinal Ganglion Cell Circuits written by Nai-Wen Tien and published by . This book was released on 2018 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: The function of our nervous system relies on specific patterns of synaptic connections between diverse neuronal cell types. My thesis research addressed how cell-type-specific patterns of connectivity emerge in the developing mouse retina and how they enable mature retinal neurons to detect specific sensory stimuli. Spike trains of the approximately 40 retinal ganglion cell (RGC) types in mammals encode specific features and events in the visual world, and are the sole source of visual information to the brain. Recent studies have begun to dissect the presynaptic circuits underlying diverse RGC light responses, but how cell-type-specific retinal circuits emerge during development is poorly understood. The first part of my dissertation explored the plasticity of the ON alpha (ON[alpha]-) RGC circuit. I found that developmental removal of the dominant excitatory input to ON[alpha]-RGCs triggers cell-type-specific rewiring, which precisely preserves ON[alpha]-RGCs' characteristic light responses including high contrast sensitivity. Spiking neurons, including RGCs, typically encode sensory information by increasing firing rates in the presence of preferred stimuli. Suppressed-by-Contrast (SbC-) RGCs are unique in that they signal changes in luminance (i.e., contrast) by decreasing rather than increasing spiking. Taking advantages of mouse genetics, in the second part of my thesis, I characterized SbC-RGCs' responses to complex stimuli and identified the synaptic mechanisms underlying their suppressive contrast encoding. Interestingly, I found that VGluT3-expressing amacrine cells (VG3-ACs) are dual transmitter neurons that release excitatory and inhibitory transmitters in a target-specific manner, and VG3-ACs specifically contributes to OFF inhibition to SbC-RGCs in response to small stimuli. Finally, using an intersectional transgenic approach, I preferentially labeled SbC-RGCs and mapped their central projections to explore the contribution of SbC-RGCs to vision.
Author : Retina Research Foundation (U.S.). Symposium
Publisher : MIT Press
ISBN 13 : 9780262121545
Total Pages : 330 pages
Book Rating : 4.1/5 (215 download)
Download or read book Development of the Visual System written by Retina Research Foundation (U.S.). Symposium and published by MIT Press. This book was released on 1991 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the Visual System presents a selection of current studies that clearly illustrate principles of visual system development. These range from retinal development in fish and frogs to the effects of abnormal visual experience on the primary visual cortex of the cat. The book is unique in addressing four specific and fundamental aspects of development: cell lineage and cell fate, specificity and targeting of axons, specification of visual cortex, and correlates of the critical period. Encompassing technical advances in cellular and molecular biology and in video imaging and microscopy, contributions in each of these areas provide new information at the cellular and molecular levels to complement the now classic descriptions of visual development previously available at the level of neural systems.ContributorsKaren L. Allendoerfer, David M. Altshuler, Antonella Antonini, Seymour Benzer, Edward M. Callaway, Constance L. Cepko, Hollis T. Cline, Max S. Cynader, N. W. Daw, Scott E. Fraser, K. Fox, Eckhard Friauf, Anirvan Ghosh, R. W. Guillery, William A. Harris, Christine E. Holt, Lawrence C. Katz, Susan McConnell, Pamela A. Raymond, Thomas A. Reh, Carla J. Shatz, Michael P. Stryker, Claudia A. 0. Stuermer, Mriganka Sur, David L. Turner, T. N. Wiesel
Author : Leo M. Chalupa
Publisher : MIT Press
ISBN 13 : 026203381X
Total Pages : 0 pages
Book Rating : 4.2/5 (62 download)
Download or read book Eye, Retina, and Visual System of the Mouse written by Leo M. Chalupa and published by MIT Press. This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive guide to current research captures the first wave of studies in the field, with fifty-nine chapters by leading scholars that demonstrate the usefulness of mouse models as a bridge between experimental and clinical research. The opening chapters introduce the mouse as a species and research model, discussing such topics as the mouse's evolutionary history and the mammalian visual system. Subsequent sections explore more specialized subjects, considering optics, psychophysics, and the visual behaviors of mice; the organization of the adult mouse eye and central visual system; the development of the mouse eye (including comparisons to human development); the development and plasticity of retinal projections and visuotopic maps; mouse models for human eye disease (including glaucoma and cataracts); and the application of advanced genomic technologies (including gene therapy and genetic knockouts) to the mouse visual system. Readers of this reference will see th.
Author : Evelyne Sernagor
Publisher : Cambridge University Press
ISBN 13 : 1139459732
Total Pages : 369 pages
Book Rating : 4.1/5 (394 download)
Download or read book Retinal Development written by Evelyne Sernagor and published by Cambridge University Press. This book was released on 2012-11-29 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced text, first published in 2006, takes a developmental approach to the presentation of our understanding of how vertebrates construct a retina. Written by experts in the field, each of the seventeen chapters covers a specific step in the process, focusing on the underlying molecular, cellular, and physiological mechanisms. There is also a special section on emerging technologies, including genomics, zebrafish genetics, and stem cell biology that are starting to yield important insights into retinal development. Primarily aimed at professionals, both biologists and clinicians working with the retina, this book provides a concise view of vertebrate retinal development. Since the retina is 'an approachable part of the brain', this book will also be attractive to all neuroscientists interested in development, as processes required to build this exquisitely organized system are ultimately relevant to all other parts of the central nervous system.
Author : Hubert Vaudry
Publisher : Springer Science & Business Media
ISBN 13 : 9781402073069
Total Pages : 432 pages
Book Rating : 4.0/5 (73 download)
Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Author : Rafael Yuste
Publisher : CSHL Press
ISBN 13 : 0879696923
Total Pages : 813 pages
Book Rating : 4.8/5 (796 download)
Download or read book Imaging in Neuroscience and Development written by Rafael Yuste and published by CSHL Press. This book was released on 2005 with total page 813 pages. Available in PDF, EPUB and Kindle. Book excerpt: As imaging studies have continued to expand in scope and sophistication, this new edition of the highly successful and well–received Imaging Neurons: A Laboratory Manualhas expanded to include development, with over twenty new chapters on such topics as MRI microscopy, imaging early developmental events, and labeling single neurons. Chapters on FRET, FCS/ICS, FRAP, hyperresolution microscopy, single molecule imaging, imaging with quantum dots, and imaging gene expression are included. With over forty full chapters, the manual also includes over forty sections of protocols for imaging techniques.
Author : John S. Werner
Publisher : MIT Press
ISBN 13 : 0262019167
Total Pages : 1693 pages
Book Rating : 4.2/5 (62 download)
Download or read book The New Visual Neurosciences written by John S. Werner and published by MIT Press. This book was released on 2013-10-25 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of contemporary research in the vision sciences, reflecting the rapid advances of recent years. Visual science is the model system for neuroscience, its findings relevant to all other areas. This essential reference to contemporary visual neuroscience covers the extraordinary range of the field today, from molecules and cell assemblies to systems and therapies. It provides a state-of-the art companion to the earlier book The Visual Neurosciences (MIT Press, 2003). This volume covers the dramatic advances made in the last decade, offering new topics, new authors, and new chapters. The New Visual Neurosciences assembles groundbreaking research, written by international authorities. Many of the 112 chapters treat seminal topics not included in the earlier book. These new topics include retinal feature detection; cortical connectomics; new approaches to mid-level vision and spatiotemporal perception; the latest understanding of how multimodal integration contributes to visual perception; new theoretical work on the role of neural oscillations in information processing; and new molecular and genetic techniques for understanding visual system development. An entirely new section covers invertebrate vision, reflecting the importance of this research in understanding fundamental principles of visual processing. Another new section treats translational visual neuroscience, covering recent progress in novel treatment modalities for optic nerve disorders, macular degeneration, and retinal cell replacement. The New Visual Neurosciences is an indispensable reference for students, teachers, researchers, clinicians, and anyone interested in contemporary neuroscience. Associate Editors Marie Burns, Joy Geng, Mark Goldman, James Handa, Andrew Ishida, George R. Mangun, Kimberley McAllister, Bruno Olshausen, Gregg Recanzone, Mandyam Srinivasan, W.Martin Usrey, Michael Webster, David Whitney Sections Retinal Mechanisms and Processes Organization of Visual Pathways Subcortical Processing Processing in Primary Visual Cortex Brightness and Color Pattern, Surface, and Shape Objects and Scenes Time, Motion, and Depth Eye Movements Cortical Mechanisms of Attention, Cognition, and Multimodal Integration Invertebrate Vision Theoretical Perspectives Molecular and Developmental Processes Translational Visual Neuroscience
Author : Leo M. Chalupa
Publisher : Springer Science & Business Media
ISBN 13 : 1461553334
Total Pages : 344 pages
Book Rating : 4.4/5 (615 download)
Download or read book Development and Organization of the Retina written by Leo M. Chalupa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development and Organization of the Retina offers an invaluable survey of contemporary research issues and methods dealing with the retina and retinal projections. The book's 19 chapters report on investigations into two areas: research into the organization of the mature retina and work on developmental issues. A sampling of chapter topics includes -- embryonic patterning of cone subtypes in the mammalian retina -- synaptic transmission between retinal neurons -- scaling the retina, macro and micro -- retinal ganglion cell axonal transport, and more.
Author : Jon H. Kaas
Publisher : CRC Press
ISBN 13 : 0203507592
Total Pages : 439 pages
Book Rating : 4.2/5 (35 download)
Download or read book The Primate Visual System written by Jon H. Kaas and published by CRC Press. This book was released on 2003-07-28 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last 20 years of research have been marked by exceptional progress in understanding the organization and functions of the primate visual system. This understanding has been based on the wide application of traditional and newly emerging methods for identifying the functionally significant subdivisions of the system, their interconnections, the
Author : John E. Dowling
Publisher : Harvard University Press
ISBN 13 : 9780674766808
Total Pages : 310 pages
Book Rating : 4.7/5 (668 download)
Download or read book The Retina written by John E. Dowling and published by Harvard University Press. This book was released on 1987 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John Simon Werner
Publisher : MIT Press
ISBN 13 : 0262033089
Total Pages : 975 pages
Book Rating : 4.2/5 (62 download)
Download or read book The Visual Neurosciences written by John Simon Werner and published by MIT Press. This book was released on 2004 with total page 975 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference book for visual science.
Author : Paride Antinucci
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)
Download or read book Function and Assembly of Teneurin-3-positive Retinal Circuits written by Paride Antinucci and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Third, a specific class of orientation-selective amacrine cells with elongated dendritic fields was identified. Notably, these cells generate orientation selectivity in retinal ganglion cells by being a source of tuned GABAergic inhibition. Lastly, evidence showing that orientation selectivity is also present in a fraction of bipolar cell presynaptic terminals is provided. In conclusion, these results define a retinal circuit processing orientation-specific information and identify essential molecular and cellular requirements for its development and function.
Author : Béla Völgyi
Publisher : Frontiers Media SA
ISBN 13 : 2889631052
Total Pages : 115 pages
Book Rating : 4.8/5 (896 download)
Download or read book Encoding Visual Features by Parallel Ganglion Cell Initiated Pathways in the Healthy, Diseased and Artificial Retina written by Béla Völgyi and published by Frontiers Media SA. This book was released on 2019-10-16 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photons are sensed by retinal photoreceptors whose matrix-like distribution underlies the transformation of illumination patterns of the visual scene into photoreceptor activity patterns in a visuotopic fashion. Activity of neighboring photoreceptors then are compared by secondary bipolar cells to decipher information regarding luminosity- and color-contrast. Bipolar cells achieve this by comparing signals received directly from their center receptive field with those come from spatially offset surrounding receptive field areas mediated by inhibitory, sign-inverting horizontal cells. This information is ultimately sent to retinal ganglion cells, the output neurons of the retina. In addition to the excitatory bipolar cell inputs, spatial and temporal features of ganglion cell activation are robustly modified by inner retinal amacrine cells through inhibitory chemical and/or excitatory electrical synaptic inputs. Ganglion cells sample various bipolar cell subtypes in their dendritic field and utilize collected inputs to generate a spike output code on luminosity-contrast, color-contrast, object motion, background motion, motion direction, changes in background illumination in a subtype specific manner. Ganglion cells in each subtype cover the retinal surface economically, thus collective information across the population provide a feature pattern and through time a feature movie to the brain. Some of these movies are utilized for image perception, whereas others are sent to accessory visual brain centers to control eye-movement, pupil contraction or circadian entrainment. A large body of information has been revealed in the past decade regarding this field, however much of the details still remain unknown or even enigmatic, including: (i) the precise description of neural circuits that serve each ganglion cell subtype to generate a specific feature movie; (ii) the estimation of the number of various ganglion cell subtypes that partake in image forming and non-image forming signaling towards the brain; (iii) the description of changes in the inputs, morphology and signaling of retinal ganglion cells when the tissue is under stress or undergoes disease related degenerative processes; (iv) the comparison of ganglion cell classes with those of the human retina and finally, (v) the practical use of all the above information to establish retina inspired visual algorithms to suit computer, drone and/or robotic vision. Therefore, research articles in this issue were collected to touch upon each of these topics and highlight recent advances of the related field.
Author : A. Kaneko
Publisher : Springer
ISBN 13 : 9784431684497
Total Pages : 253 pages
Book Rating : 4.6/5 (844 download)
Download or read book The Neural Basis of Early Vision written by A. Kaneko and published by Springer. This book was released on 2012-03-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers in recent decades have elucidated signal transduction in the retina and the function of the visual cortex. The highly flexible nature of neural circuits in the visual cortex especially during the critical period has been an interesting subject for studying neural plasticity and development. Recent advances in the visual neurosciences of the vertebrate retina and the visual cortex were discussed during the 12th Keio International Symposium for Life Science and Medicine, meeting jointly with Vision Forum 2002. Contributions to the symposium collected in this volume reflect the convergence of physiological, cell biological, molecular, mathematical, and clinical approaches. The book covers topics ranging from phototransduction to visual information processing in the primary visual cortex, and includes clinical studies on hereditary night blindness, creating a valuable source of information for researchers and clinicians in the visual neurosciences.
Author : Sebastian Seung
Publisher : HMH
ISBN 13 : 0547508174
Total Pages : 389 pages
Book Rating : 4.5/5 (475 download)
Download or read book Connectome written by Sebastian Seung and published by HMH. This book was released on 2012-02-07 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Accessible, witty . . . an important new researcher, philosopher and popularizer of brain science . . . on par with cosmology’s Brian Greene and the late Carl Sagan” (The Plain Dealer). One of the Wall Street Journal’s 10 Best Nonfiction Books of the Year and a Publishers Weekly “Top Ten in Science” Title Every person is unique, but science has struggled to pinpoint where, precisely, that uniqueness resides. Our genome may determine our eye color and even aspects of our character. But our friendships, failures, and passions also shape who we are. The question is: How? Sebastian Seung is at the forefront of a revolution in neuroscience. He believes that our identity lies not in our genes, but in the connections between our brain cells—our particular wiring. Seung and a dedicated group of researchers are leading the effort to map these connections, neuron by neuron, synapse by synapse. It’s a monumental effort, but if they succeed, they will uncover the basis of personality, identity, intelligence, memory, and perhaps disorders such as autism and schizophrenia. Connectome is a mind-bending adventure story offering a daring scientific and technological vision for understanding what makes us who we are, as individuals and as a species. “This is complicated stuff, and it is a testament to Dr. Seung’s remarkable clarity of exposition that the reader is swept along with his enthusiasm, as he moves from the basics of neuroscience out to the farthest regions of the hypothetical, sketching out a spectacularly illustrated giant map of the universe of man.” —TheNew York Times “An elegant primer on what’s known about how the brain is organized and how it grows, wires its neurons, perceives its environment, modifies or repairs itself, and stores information. Seung is a clear, lively writer who chooses vivid examples.” —TheWashington Post
Author : Santiago Ramón y Cajal
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)
Download or read book Studies on Vertebrate Neurogenesis written by Santiago Ramón y Cajal and published by . This book was released on 1960 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
