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Development And Application Of Two Step Laser Desorption Multiphoton Ionization Mass Spectrometry
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Book Synopsis Development and Application of Two-step Laser Desorption/multiphoton Ionization Mass Spectrometry by : Jong Hoon Hahn
Download or read book Development and Application of Two-step Laser Desorption/multiphoton Ionization Mass Spectrometry written by Jong Hoon Hahn and published by . This book was released on 1988 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Photoionization and Photo-Induced Processes in Mass Spectrometry by : Ralf Zimmermann
Download or read book Photoionization and Photo-Induced Processes in Mass Spectrometry written by Ralf Zimmermann and published by John Wiley & Sons. This book was released on 2021-07-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of laser-induced ionization processes for mass spectrometry analysis Drawing on the expertise of the leading academic and industrial research groups involved in the development of photoionization methods for mass spectrometry, this reference for analytical scientists covers both the theory and current applications of photo-induced ionization processes. It places widely used techniques such as MALDI side by side with more specialist approaches such as REMPI and RIMS, and discusses leading edge developments in ultrashort laser pulse desorption, to give readers a complete picture of the state of the technology. Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications starts with a complete overview of the fundamentals of the technique, covering the basics of the gas phase ionization as well as those of laser desorption and ablation, pulse photoionization, and single particle ionization. Numerous application examples from different analytical fields are described that showcase the power and the wide scope of photo ionization in mass spectrometry. -The first general reference book on photoionization techniques for mass spectrometry -Examines technologies and applications of gas phase resonance-enhanced multiphoton ionization mass spectrometry (REMPI-MS) and gas phase resonance ionization mass spectrometry (RIMS) -Provides complete coverage of popular techniques like MALDI -Discusses the current and potential applications of each technology, focusing on process and environmental analysis Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications is an excellent book for spectroscopists, analytical chemists, photochemists, physical chemists, and laser specialists.
Book Synopsis Laser Photoionization Spectroscopy by : Vladilen Letokhov
Download or read book Laser Photoionization Spectroscopy written by Vladilen Letokhov and published by Elsevier. This book was released on 2012-12-02 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laser Photoionization Spectroscopy discusses the features and the development of photoionization technique. This book explores the progress in the application of lasers, which improve the characteristics of spectroscopic methods. Organized into 12 chapters, this book starts with an overview of the fundamentals of the method for atoms and molecules. This text then examines the photoionization spectroscopy, which is based on the laser resonant excitation of particles into high-lying quantum states that are easy to detect by ionization. Other chapters explain the various basic schemes of multistep excitation, which can be used for resonance photoionization of molecules. This book discusses as well the different applications of the resonance photoionization technique in atomic and molecular spectroscopy. The final chapter considers the two well-known types of microscopy, namely, wave and corpuscular. This book is a valuable resource for chemists, physicists, analysts, and geochemists who are interested in laser spectroscopy techniques to solve nontrivial problems.
Book Synopsis Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: From Material Design to Mechanistic Understanding by : Moon-Ju Kim
Download or read book Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: From Material Design to Mechanistic Understanding written by Moon-Ju Kim and published by Springer Nature. This book was released on 2023-11-11 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is currently facing and for enhancing LDI efficiency. It presents a variety of cutting-edge nanophotonic structures to satisfy the mass-analytical needs of sensitivity, reproducibility, and quantification. As opposed to the commercialized, conventional organic matrix used in MALDI-MS, these nanostructures are validated to be highly effective in detecting small metabolites and drugs, highlighting their considerable potential in the mass spectrometry field. It also systematically elucidates fundamental LDI processes in terms of the photo-thermal, electronic, and structural characteristics of nanophotonic structures, offering mechanistic knowledge of LDI-MS. Even though LDI-MS performance is heavily influenced by a number of nanostructure parameters, relatively little is known about the LDI processes associated with those characteristics. An in-depth understanding of nanostructure characteristics and LDI mechanisms thus paves the way for more effective, rational design and development of nanostructures with improved LDI capabilities. Further, with a focus on multiple cascades in nanostructure functions in response to laser pulse stimuli, this book provides detailed, step-by-step procedures to design and construct a nanophotonic, LDI-active platform, which may serve as a roadmap for graduate students in the field of mass spectrometry. Readers, including graduate students, researchers, and experts working in the related areas of mass spectrometry, nanophotonics, and material science and material engineering, will find a wealth of useful information in this book.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2004 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Matrix-assisted Laser Desorption Ionization Mass Spectrometry by : Jonathon Kevin Gooden
Download or read book Matrix-assisted Laser Desorption Ionization Mass Spectrometry written by Jonathon Kevin Gooden and published by . This book was released on 2005 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development and Application of Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution Studies by : Mark Thomas Bokhart
Download or read book Development and Application of Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution Studies written by Mark Thomas Bokhart and published by . This book was released on 2017 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Cosmic Dust Connection by : J. Mayo Greenberg
Download or read book The Cosmic Dust Connection written by J. Mayo Greenberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid particles are followed from their creation through their evolution in the Galaxy to their participation in the formation of solar systems like our own, these being now clearly deduced from observations by the Hubble Space Telescope as well as by IR and visual observations of protostellar disks, like that of the famous Beta Pictoris object. The most recent observational, laboratory and theoretical methods are examined in detail. In our own solar system, studies of meteorites, comets and comet dust reveal many features that follow directly from the interstellar dust from which they formed. The properties of interstellar dust provide possible keys to its origin in comets and asteroids and its ultimate origin in the early solar system. But this is a continuing story: what happens to the solid particles in space after they emerge from stellar sources has important scientific consequences since it ultimately bears on our own origins - the origins of solar systems and, especially, of our own earth and life in the universe.
Book Synopsis Developments and Applications of Electrophoresis and Small Molecule Laser Desorption Ionization Mass Spectrometry by : Hui Zhang
Download or read book Developments and Applications of Electrophoresis and Small Molecule Laser Desorption Ionization Mass Spectrometry written by Hui Zhang and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Multiphoton Processes and Spectroscopy by : S. H. Lin
Download or read book Advances in Multiphoton Processes and Spectroscopy written by S. H. Lin and published by World Scientific. This book was released on 1991 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of the rapid growth in both experimental and theoretical studies of multiphoton processes and multiphoton spectroscopy of atoms, ions, and molecules in chemistry, physics, biology, materials sciences, etc., it is desirable to publish an Advanced Series that contains review papers readable not only by active researchers in these areas, but also by those who are not experts in the field but who intend to enter the field. The present series attempts to serve this purpose. Each review article is written in a self-contained manner by experts in the area so that the readers can grasp the knowledge in the area without too much preparation. This volume will be useful not only to active researchers but also to other scientists in the area of biology, chemistry, materials science, and physics.
Book Synopsis Two-step Laser Mass Spectrometry by : Renato Zenobi
Download or read book Two-step Laser Mass Spectrometry written by Renato Zenobi and published by . This book was released on 1990 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Laser Mass Spectrometry by : Patrick John McKeown
Download or read book Laser Mass Spectrometry written by Patrick John McKeown and published by . This book was released on 1992 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies on Surface-Assisted Laser Desorption/Ionization and Its Analytical Application in Imaging Mass Spectrometry by : Ho-Wai Tang
Download or read book Studies on Surface-Assisted Laser Desorption/Ionization and Its Analytical Application in Imaging Mass Spectrometry written by Ho-Wai Tang and published by . This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Studies on surface-assisted laser desorption/ionization and its analytical application in imaging mass spectrometry" by Ho-wai, Tang, 鄧浩維, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) is an analytical technique enabling direct chemical analysis of solid samples. Analytes could be desorbed/ionized upon nitrogen laser irradiation from a SALDI substrate-coated sample, then analyzed by MS. The substrate is involved in the transfer of laser energy to the analytes, and eventually assists the desorption/ionization of analytes. The analytical performance of SALDI-MS, such as detection sensitivity, is dependent on different parameters of the substrate, such as size, morphology and form. In this thesis, the effects of several substrate parameters on the SALDI process were investigated. SALDI-MS based Imaging Mass Spectrometry (IMS) method was also developed using efficient SALDI substrate identified in the fundamental studies. IMS is a chemical-specific mapping technique which allows parallel mapping of multiple analytes in solid samples. The desorption mechanism of SALDI is investigated using two groups of substrate, the carbon allotropes and the noble metal nanoparticles. Ion desorption efficiency and internal energy transfer were probed and correlated in carbon-based SALDI. It was found that the ion desorption efficiency and internal energy transfer was in opposite order. Substrate that transferred more internal energy to ions did not show higher ion desorption efficiency. This result could not be explained by the Thermal Desorption model which was a generally believed mechanism of the SALDI desorption process. A non-thermal model, the Phase Transition model is proposed to account for the SALDI desorption process. The Phase Transition model suggests that the substrate is melted/ restructured upon laser irradiation, and this will assist ion desorption. The Phase Transition model is supported by the morphological change of carbon substrates after SALDI and high initial velocity of ions desorbed by carbon-based SALDI (> 1,000 ms-1). SALDI-MS is useful for small molecule analysis due to the relatively clean background in the low mass region. SALDI-IMS is developed and applied to the imaging of spatial distribution of small molecules in forensic and biological samples. Gold nanoparticles (AuNPs) was selected as the substrate from several other noble metal NPs. A solvent-free method, argon ion sputtering, was employed for coating AuNPs on sample surface prior to SALDI-IMS analysis. Fine details of the samples, such as the fine pattern of latent fingerprints and handwriting on questioned documents can be preserved and imaged reliably by avoiding the use of solvent. Fatty acids, drugs and ink components can be imaged in forensic samples including latent fingerprints, banknotes and checks. The solvent-free SALDI-IMS method was also applied to image the distribution of metabolites in intact animal tissues. Spatial distributions of neurotransmitters, nucleobases and fatty acids can be imaged from mouse brain and tumor tissue sections. DOI: 10.5353/th_b4714555 Subjects: Mass spectrometry Imaging systems
Book Synopsis Development and Application of Novel Matrices Under Matrix-assisted Laser Desorption/ionization Time-of-flight (MALDI-TOF) Mass Spectrometry Conditions by : Bharat R. Mankani
Download or read book Development and Application of Novel Matrices Under Matrix-assisted Laser Desorption/ionization Time-of-flight (MALDI-TOF) Mass Spectrometry Conditions written by Bharat R. Mankani and published by . This book was released on 2010 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry by : Rainer Cramer
Download or read book Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry written by Rainer Cramer and published by Springer. This book was released on 2015-11-09 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics
Book Synopsis THE APPLICABILITY OF RESONANT TWO-PHOTON IONIZATION AND PULSED LASER DESORPTION IN SUPERSONIC BEAM MASS SPECTROMETRY. by : ROGER DALE TEMBREULL
Download or read book THE APPLICABILITY OF RESONANT TWO-PHOTON IONIZATION AND PULSED LASER DESORPTION IN SUPERSONIC BEAM MASS SPECTROMETRY. written by ROGER DALE TEMBREULL and published by . This book was released on 1986 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: molecule are obtained.
Book Synopsis Developments in Laser Desorption and Photodissociation Fourier Transform Mass Spectrometry by : Lydia Marie Nuwaysir
Download or read book Developments in Laser Desorption and Photodissociation Fourier Transform Mass Spectrometry written by Lydia Marie Nuwaysir and published by . This book was released on 1990 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt:
