Developing Multimodal Therapies for Brain Disorders

Download Developing Multimodal Therapies for Brain Disorders PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309450268
Total Pages : 97 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!


Book Synopsis Developing Multimodal Therapies for Brain Disorders by : National Academies of Sciences, Engineering, and Medicine

Download or read book Developing Multimodal Therapies for Brain Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-03-13 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potentialâ€"and perhaps essentialâ€"ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop.

Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬"Brain Barrier

Download Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬

Author :
Publisher : National Academies Press
ISBN 13 : 0309473071
Total Pages : 73 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!


Book Synopsis Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬"Brain Barrier by : National Academies of Sciences, Engineering, and Medicine

Download or read book Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬"Brain Barrier written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-06-29 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the bloodâ€"brain barrier (BBB). The Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the challenges associated with the BBB that have thus far stymied development of CNS drugs, examine new technologies that could address these challenges, and highlight potential opportunities for moving the field forward. This publication summarizes the presentations and discussions from the workshop.

Machine Learning

Download Machine Learning PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128157402
Total Pages : 412 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Machine Learning by : Andrea Mechelli

Download or read book Machine Learning written by Andrea Mechelli and published by Academic Press. This book was released on 2019-11-14 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine Learning is an area of artificial intelligence involving the development of algorithms to discover trends and patterns in existing data; this information can then be used to make predictions on new data. A growing number of researchers and clinicians are using machine learning methods to develop and validate tools for assisting the diagnosis and treatment of patients with brain disorders. Machine Learning: Methods and Applications to Brain Disorders provides an up-to-date overview of how these methods can be applied to brain disorders, including both psychiatric and neurological disease. This book is written for a non-technical audience, such as neuroscientists, psychologists, psychiatrists, neurologists and health care practitioners. Provides a non-technical introduction to machine learning and applications to brain disorders Includes a detailed description of the most commonly used machine learning algorithms as well as some novel and promising approaches Covers the main methodological challenges in the application of machine learning to brain disorders Provides a step-by-step tutorial for implementing a machine learning pipeline to neuroimaging data in Python

Magnetoencephalography

Download Magnetoencephalography PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3642330452
Total Pages : 999 pages
Book Rating : 4.6/5 (423 download)

DOWNLOAD NOW!


Book Synopsis Magnetoencephalography by : Selma Supek

Download or read book Magnetoencephalography written by Selma Supek and published by Springer. This book was released on 2014-08-07 with total page 999 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.

Handbook of Innovations in Central Nervous System Regenerative Medicine

Download Handbook of Innovations in Central Nervous System Regenerative Medicine PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0128180854
Total Pages : 712 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Handbook of Innovations in Central Nervous System Regenerative Medicine by : António Salgado

Download or read book Handbook of Innovations in Central Nervous System Regenerative Medicine written by António Salgado and published by Elsevier. This book was released on 2020-06-10 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Personalized Psychiatry

Download Personalized Psychiatry PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128131772
Total Pages : 604 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Personalized Psychiatry by : Bernhard Baune

Download or read book Personalized Psychiatry written by Bernhard Baune and published by Academic Press. This book was released on 2019-10-16 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Hands-On Machine Learning with R

Download Hands-On Machine Learning with R PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1000730433
Total Pages : 374 pages
Book Rating : 4.0/5 (7 download)

DOWNLOAD NOW!


Book Synopsis Hands-On Machine Learning with R by : Brad Boehmke

Download or read book Hands-On Machine Learning with R written by Brad Boehmke and published by CRC Press. This book was released on 2019-11-07 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on Machine Learning with R provides a practical and applied approach to learning and developing intuition into today’s most popular machine learning methods. This book serves as a practitioner’s guide to the machine learning process and is meant to help the reader learn to apply the machine learning stack within R, which includes using various R packages such as glmnet, h2o, ranger, xgboost, keras, and others to effectively model and gain insight from their data. The book favors a hands-on approach, providing an intuitive understanding of machine learning concepts through concrete examples and just a little bit of theory. Throughout this book, the reader will be exposed to the entire machine learning process including feature engineering, resampling, hyperparameter tuning, model evaluation, and interpretation. The reader will be exposed to powerful algorithms such as regularized regression, random forests, gradient boosting machines, deep learning, generalized low rank models, and more! By favoring a hands-on approach and using real word data, the reader will gain an intuitive understanding of the architectures and engines that drive these algorithms and packages, understand when and how to tune the various hyperparameters, and be able to interpret model results. By the end of this book, the reader should have a firm grasp of R’s machine learning stack and be able to implement a systematic approach for producing high quality modeling results. Features: · Offers a practical and applied introduction to the most popular machine learning methods. · Topics covered include feature engineering, resampling, deep learning and more. · Uses a hands-on approach and real world data.

Aging and Dementia

Download Aging and Dementia PDF Online Free

Author :
Publisher : Spectrum _
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Aging and Dementia by : Wallace Lynn Smith

Download or read book Aging and Dementia written by Wallace Lynn Smith and published by Spectrum _. This book was released on 1977 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Artificial Intelligence for Medicine

Download Artificial Intelligence for Medicine PDF Online Free

Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110717859
Total Pages : 520 pages
Book Rating : 4.1/5 (17 download)

DOWNLOAD NOW!


Book Synopsis Artificial Intelligence for Medicine by : Yoshiki Oshida

Download or read book Artificial Intelligence for Medicine written by Yoshiki Oshida and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-10-11 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of artificial intelligence (AI) in various fields is of major importance to improve the use of resourses and time. This book provides an analysis of how AI is used in both the medical field and beyond. Topics that will be covered are bioinformatics, biostatistics, dentistry, diagnosis and prognosis, smart materials, and drug discovery as they intersect with AI. Also, an outlook of the future of an AI-assisted society will be explored.

Pain Management and the Opioid Epidemic

Download Pain Management and the Opioid Epidemic PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!


Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Functional Neurologic Disorders

Download Functional Neurologic Disorders PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128018496
Total Pages : 684 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Functional Neurologic Disorders by :

Download or read book Functional Neurologic Disorders written by and published by Academic Press. This book was released on 2016-10-06 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders). Offers a comprehensive interdisciplinary approach for the care of patients with functional disorders seen in neurologic practice, leading to more efficient prevention, management, and treatment Provides a synthesis of research efforts incorporating clinical, brain imaging and neurophysiological studies Fills an existing gap between traditional neurology and traditional psychiatry Contents include coverage of history, epidemiology, clinical presentations, and therapy Edited work with chapters authored by leaders in the field, the broadest, most expert coverage available

Neurobiology of Brain Disorders

Download Neurobiology of Brain Disorders PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0323898254
Total Pages : 1136 pages
Book Rating : 4.3/5 (238 download)

DOWNLOAD NOW!


Book Synopsis Neurobiology of Brain Disorders by : Michael J. Zigmond

Download or read book Neurobiology of Brain Disorders written by Michael J. Zigmond and published by Academic Press. This book was released on 2022-05-20 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function. Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more. Links basic, translational and clinical research on disorders of the nervous system Covers a vast array of neurological and psychiatric disorders, including Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson's, Huntington's, Alzheimer's, OCD, PTSD, schizophrenia, depression and pain Features new chapters on the effects of aging and isolation on brain health Expands coverage on disorders, including new chapters on fibromyalgia, chronic fatigue, and restless legs syndrome Features in-text summary points, special feature boxes and research questions

Disconnected Kids

Download Disconnected Kids PDF Online Free

Author :
Publisher : Penguin
ISBN 13 : 9780399534751
Total Pages : 292 pages
Book Rating : 4.5/5 (347 download)

DOWNLOAD NOW!


Book Synopsis Disconnected Kids by : Robert Melillo

Download or read book Disconnected Kids written by Robert Melillo and published by Penguin. This book was released on 2009 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a bold new understanding of the causes of such disorders as autism, ADHD, Asperger's, dyslexia, and OCD, an effective drug-free program addresses both the symptoms and causes of conditions involving a disconnection between the left and right sides of the developing brain, with customizable exercises, behavior modification advice, nutritional guidelines, and more.

Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders

Download Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128041188
Total Pages : 580 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders by : Elizabeth B. Torres

Download or read book Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders written by Elizabeth B. Torres and published by Academic Press. This book was released on 2018-06-29 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders provides a new and unifying methodological framework, introducing new objective biometrics to characterize patterns of sensory motor control underlying symptoms. Its goal is to radically transform the ways in which disorders of the nervous system are currently diagnosed, tracked, researched and treated. This book introduces new ways to bring the laboratory to the clinical setting, to schools and to settings of occupational and physical therapy. Ready-to-use, graphic user interfaces are introduced to provide outcome measures from wearable sensors that automatically assess in near real time the effectiveness of interventions. Lastly, examples of how the new framework has been effectively utilized in the context of clinical trials are provided. Provides methods and implementation strategies using real data and simple computer programs that less technical students and researchers can utilize Contains appendices with computer code in MATLAB, along with data samples to generate graphics displayed on figures in each chapter Presents videos that illustrate the experimental setup for each situation/method described

Genomic and Personalized Medicine

Download Genomic and Personalized Medicine PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0123822289
Total Pages : 1350 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!


Book Synopsis Genomic and Personalized Medicine by :

Download or read book Genomic and Personalized Medicine written by and published by Academic Press. This book was released on 2012-10-30 with total page 1350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003. Highly Commended 2013 BMA Medical Book Award for Medicine More than 100 chapters, from leading researchers, review the many impacts of genomic discoveries in clinical action, including 63 chapters new to this edition Discusses state-of-the-art genome technologies, including population screening, novel diagnostics, and gene-based therapeutics Wide and inclusive discussion encompasses the formidable ethical, legal, regulatory and social challenges related to the evolving practice of genomic medicine Clearly and beautifully illustrated with 280 color figures, and many thousands of references for further reading and deeper analysis

Textbook of Personalized Medicine

Download Textbook of Personalized Medicine PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030620808
Total Pages : 744 pages
Book Rating : 4.0/5 (36 download)

DOWNLOAD NOW!


Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain

Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Springer Nature. This book was released on 2020-12-05 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considers genetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This comprehensive third edition covers the latest advances in personalized medicine and several chapters are devoted to various specialties, particulary cancer which is the largest area of application. The book discusses the development of personalized medicine and various players in it such as companies, academic institutions, the government, and the public as the consumer of healthcare. Additionally, the roles of bioinformatics, electronic health records, and digital technologies for personalized medicine are discussed. Textbook of Personalized Medicine, 3rd Edition serves as a convenient source of information for students at many levels and in a wide range of fields, including physicians, scientists, and decision makers in the biopharmaceutical and healthcare industries.

Oxford Textbook of Attention Deficit Hyperactivity Disorder

Download Oxford Textbook of Attention Deficit Hyperactivity Disorder PDF Online Free

Author :
Publisher : Oxford University Press
ISBN 13 : 0198739257
Total Pages : 473 pages
Book Rating : 4.1/5 (987 download)

DOWNLOAD NOW!


Book Synopsis Oxford Textbook of Attention Deficit Hyperactivity Disorder by : Tobias Banaschewski

Download or read book Oxford Textbook of Attention Deficit Hyperactivity Disorder written by Tobias Banaschewski and published by Oxford University Press. This book was released on 2018 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxford Textbook of Attention Deficit Hyperactivity Disorder is an authoritative, multi-disciplinary text covering the diagnosis, assessment and management of patients with ADHD.