Deprenyl — Past and Future

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Publisher : Springer Science & Business Media
ISBN 13 : 3709174945
Total Pages : 191 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Deprenyl — Past and Future by : Wilfried Kuhn

Download or read book Deprenyl — Past and Future written by Wilfried Kuhn and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert clinicians and basic scientists with a special interest in Parkinson's disease review the current state of science and clinical therapeutics of the disease. Therefore these articles represent an authorative review of the current state of knowledge regarding preclinical course and symptomatology, subtypes with their impact on the pathology, genetic alterations, novel mechanisms of neuronal cell death, diagnostic tools and old and novel therapeutic approaches with respect to neuroprotection and neuroregeneration in Parkinson's disease. Particular emphasis has been placed on a novel antiparkinsonian drug called budipine with various modes of action also influencing altered non dopaminergic systems in Parkinson's disease. It is evident, that many questions on the cause, course and treatment of Parkinson's disease are still unanswered and therefore the ideal way to treat a parkinsonian patient remains to be defined.

How Selegiline ((-)-Deprenyl) Slows Brain Aging

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1608054705
Total Pages : 161 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis How Selegiline ((-)-Deprenyl) Slows Brain Aging by : Joseph Knoll

Download or read book How Selegiline ((-)-Deprenyl) Slows Brain Aging written by Joseph Knoll and published by Bentham Science Publishers. This book was released on 2012-10-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book is a reference on Selegiline ((-)-Deprenyl) effects on the brain. Selegiline, described in thousands of research papers, is registered in over 60 countries. At present, more than one hundred preparations containing selegiline circulate in the global market under different brand names. They are widely used in the treatment of Parkinson's disease, Alzheimer's disease, major depression and as a geroprotective / anti-aging drug. ((-)-Deprenyl) selegiline, the first selective inhibitor of B-type MAO which, in contrast to the known MAO inhibitors, did not potentiate the effect of tyramine but inhibited it. the compound could be combined with levodopa in Parkinson's disease without signs of hypertensive reactions. the DATATOP study in the USA revealed that (-)-deprenyl delayed the onset of disability associated with early, otherwise untreated Parkinson's disease. the age-related decay of the supply of the brain with phenylethylamine (PEA), due to the progressive increase of MAO-B activity in the aging brain, and dopamine, due to the better than average decline of the dopaminergic neuronal activity during the postdevelopmental phase of life, are irresistible biochemical lesions of aging. the speed of deterioration of behavioral performances with the passing of time and longevity depends significantly on the pace of the worsening of these lesions. (-)-Deprenyl, increasing the supply of the brain with PEA and dopamine, counteracts this aging process. Maintenance of male rats from sexual maturity until death on ((-)-deprenyl) delays the age-related loss of the capacity to ejaculate, slows the age-related decline of learning ability and prolongs life. In humans, maintenance from sexual maturity on (-)-deprenyl (1 mg daily) is, for the time being, the most promising prophylactic treatment to fight against the age-related decay of behavioral performances, prolonging life, and preventing or delaying the onset of age-related neurodegenerative diseases such as Parkinson's and Alzheimer's. This e-book is a useful reference for graduate medical students, academic researchers in the field of neuropsychopharmacology, neurophysiology and gerontology and professional research groups in commercial organizations manufacturing selegiline preparations.

Morbus Parkinson Selegilin (R-(—)-Deprenyl); Movergan®

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3709122872
Total Pages : 207 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Morbus Parkinson Selegilin (R-(—)-Deprenyl); Movergan® by : Peter Riederer

Download or read book Morbus Parkinson Selegilin (R-(—)-Deprenyl); Movergan® written by Peter Riederer and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International Symposium in Berlin, January 23-25, 1987

Dose-dependent Effects of Deprenyl on CSF Monoamine Metabolites in Patients with Alzheimer's Disease

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Author :
Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Dose-dependent Effects of Deprenyl on CSF Monoamine Metabolites in Patients with Alzheimer's Disease by :

Download or read book Dose-dependent Effects of Deprenyl on CSF Monoamine Metabolites in Patients with Alzheimer's Disease written by and published by . This book was released on 1987 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Parkinson's Disease and Related Disorders

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Publisher : Springer Science & Business Media
ISBN 13 : 3211452958
Total Pages : 484 pages
Book Rating : 4.2/5 (114 download)

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Book Synopsis Parkinson's Disease and Related Disorders by : Peter Riederer

Download or read book Parkinson's Disease and Related Disorders written by Peter Riederer and published by Springer Science & Business Media. This book was released on 2006-11-23 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders. The book is the result of the 16th International Congress of Parkinson’s Disease and Related disorders congress 2005. Its contents are suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticians and patients as well as their relatives.

NeuroPsychopharmacotherapy

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Author :
Publisher : Springer Nature
ISBN 13 : 303062059X
Total Pages : 4652 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis NeuroPsychopharmacotherapy by : Peter Riederer

Download or read book NeuroPsychopharmacotherapy written by Peter Riederer and published by Springer Nature. This book was released on 2022-11-04 with total page 4652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a reference guide describing the current status of medication in all major psychiatric and neurological indications, together with comparisons of pharmacological treatment strategies in clinical settings in Europe, USA, Japan and China. In addition, it highlights herbal medicine as used in China and Japan, as well as complementary medicine and nutritional aspects. This novel approach offers international readers a global approach in a single dedicated publication and is also a valuable resource for anyone interested in comparing treatments for psychiatric disorders in three different cultural areas. There are three volumes devoted to Basic Principles and General Aspects, offering a general overview of psychopharmacotherapy (Vol. 1); Classes, Drugs and Special Aspects covering the role of psychotropic drugs in the field of psychiatry and neurology (Vol. 2) and Applied Psychopharmacotherapy focusing on applied psychopharmacotherapy (Vol. 3). These books are invaluable to psychiatrists, neurologists, neuroscientists, medical practitioners and clinical psychologists.

MAO - The Mother of all Amine Oxidases

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Publisher : Springer Science & Business Media
ISBN 13 : 9783211830383
Total Pages : 392 pages
Book Rating : 4.8/5 (33 download)

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Book Synopsis MAO - The Mother of all Amine Oxidases by : J. P. M. Finberg

Download or read book MAO - The Mother of all Amine Oxidases written by J. P. M. Finberg and published by Springer Science & Business Media. This book was released on 1998 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monoamine oxidase (MAO) is linked to psychiatric and neurological disorders, because inhibitors of the enzyme are used clinically for treatment of affective disorders and Parkinsona (TM)s disease. One of the interesting new aspects of MAO is the occurrence in the human population of deletions of genes coding for one or the other enzyme subtype (A or B). This leads to the possibility of a genetic basis for psychiatric disorders based on MAO. Subjects with deletions of type A or B, and combined deletions, have been described. In the first group of 6 papers in this book, the occurrence and characterization of these phenotypes, as well as the structure of MAO genes, is explored. Advances in the biochemistry of MAO subtypes and their physiological function and localization in brain and periphery is included. Other sections of the book deal with the neuroprotective action of MAO inhibitors and their pharmacology, especially the pharmacology of new MAO-B inhibitors.

Davis's Drug Guide for Rehabilitation Professionals

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Author :
Publisher : F.A. Davis
ISBN 13 : 0803640048
Total Pages : 1217 pages
Book Rating : 4.8/5 (36 download)

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Book Synopsis Davis's Drug Guide for Rehabilitation Professionals by : Charles D. Ciccone

Download or read book Davis's Drug Guide for Rehabilitation Professionals written by Charles D. Ciccone and published by F.A. Davis. This book was released on 2013-03-21 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

Oxidative Stress and Neuroprotection

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Publisher : Springer
ISBN 13 : 9783709117361
Total Pages : 0 pages
Book Rating : 4.1/5 (173 download)

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Book Synopsis Oxidative Stress and Neuroprotection by : S.H. Parvez

Download or read book Oxidative Stress and Neuroprotection written by S.H. Parvez and published by Springer. This book was released on 2014-11-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.

Advances in Neurology

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Publisher :
ISBN 13 :
Total Pages : 630 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Advances in Neurology by :

Download or read book Advances in Neurology written by and published by . This book was released on 1973 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Parkinson's Disease

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Parkinson's Disease by : Max B. Streifler

Download or read book Parkinson's Disease written by Max B. Streifler and published by Lippincott Williams & Wilkins. This book was released on 1990 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Parkinson's Disease

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Author :
Publisher : Simon and Schuster
ISBN 13 : 0671768190
Total Pages : 276 pages
Book Rating : 4.6/5 (717 download)

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Book Synopsis Parkinson's Disease by : Abraham N. Lieberman

Download or read book Parkinson's Disease written by Abraham N. Lieberman and published by Simon and Schuster. This book was released on 1993-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide for Parkinson patients and their caregivers that addresses the body and the spirit.

Veterinary Psychopharmacology

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Publisher : John Wiley & Sons
ISBN 13 : 0470344148
Total Pages : 288 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Veterinary Psychopharmacology by : Sharon L. Crowell-Davis

Download or read book Veterinary Psychopharmacology written by Sharon L. Crowell-Davis and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day veterinarians in practice are asked to treat petsexhibiting problem behaviors. In the last several yearspharmacologic treatments of behavior have made significant advancesand can serve as a critical part of therapy. Veterinary Pscyhopharmacology is a complete source of currentknowledge on the subject of pharmacologic behavior modificationthat veterinarians can turn to for the answers they need. Classification of disorders is eschewed in favor of in-depthexplanations of pharmacologic options in inducing behavior changes.Special emphasis is given to explaining the underlying mechanism ofpharmacologic agents used in therapy; thus, veterinarians will knownot only which drugs to prescribe but why they should be prescribedand how they work. Veterinary behaviorists, their students and residents, veterinarypractitioners of all levels, and veterinary students will find thisbook invaluable in providing information about their patients'behavior problems and the psychoactive medications that might helpthem.

Alzheimer’s Disease - From Basic Research to Clinical Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 3709175089
Total Pages : 313 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Alzheimer’s Disease - From Basic Research to Clinical Applications by : Hermann J. Gertz

Download or read book Alzheimer’s Disease - From Basic Research to Clinical Applications written by Hermann J. Gertz and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: As human longevity continues to be extended, so will the impact of age-associated dementia on individual lives and society. Alzheimer’s disease as the most common cause of dementia in the elderly remains a sentinal problem and its underlying pathology is still poorly understood. Available therapeutic strategies require considerable refinement and the development of new therapeutic strategies need input from basic research. Thus continued efforts are necessary both to understand basic mechanisms of the condition and to achieve more powerfull therapies. This volume brings together the reports of basic scientists and clinical investigators. The chapters provide a spectrum of information valuable for clinicians and scientists. This issue bridges the gap between laboratory work in basic science and the development of urgently needed therapeutic strategies. Areas presented are the molecular and cellular biology of the disease, pathogenetic mechanisms and potential therapeutic targets, genetics, risk factors, strategies of prevention and treatment as well as practical aspects of medical and social care for patients with Alzheimer’s disease.

Clinical Handbook for the Management of Mood Disorders

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Publisher : Cambridge University Press
ISBN 13 : 1107024633
Total Pages : 429 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Handbook for the Management of Mood Disorders by : J. John Mann

Download or read book Clinical Handbook for the Management of Mood Disorders written by J. John Mann and published by Cambridge University Press. This book was released on 2013-05-09 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a one-stop evidence-based guide to the management of all types of mood disorders.

Journal Canadien Des Sciences Neurologiques

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Publisher :
ISBN 13 :
Total Pages : 684 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Journal Canadien Des Sciences Neurologiques by :

Download or read book Journal Canadien Des Sciences Neurologiques written by and published by . This book was released on 1992 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Case of the Frozen Addicts

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Author :
Publisher : IOS Press
ISBN 13 : 1614993327
Total Pages : 264 pages
Book Rating : 4.6/5 (149 download)

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Book Synopsis The Case of the Frozen Addicts by : J.W. Langston

Download or read book The Case of the Frozen Addicts written by J.W. Langston and published by IOS Press. This book was released on 2013-12-02 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the summer of 1982, hospital emergency rooms in the San Francisco Bay Area were suddenly confronted with mysteriously “frozen” patients – young men and women who, though conscious, could neither move nor speak. Doctors were baffled, until neurologist J. William Langston, recognizing the symptoms of advanced Parkinson’s disease, administered L-dopa – the only known effective treatment – and “unfroze” his patient. Dr. Langston determined that this patient and five others had all used the same tainted batch of synthetic heroin, inadvertently laced with a toxin that had destroyed an area of their brains essential to normal movement. This same area, the substantia nigra, slowly deteriorates in Parkinson’s disease. As scientists raced to capitalize on this breakthrough, Dr. Langston struggled to salvage the lives of his frozen patients, for whom L-dopa provided only short-term relief. The solution he found lay in the most daring area of research: fetal-tissue transplants. The astonishing recovery of two of his patients garnered worldwide press coverage, helped overturn federal restrictions on fetal-tissue research, and offered hope to millions suffering from Parkinson’s, Alzheimer’s, and other degenerative brain disorders. This is the story behind the headline – a spellbinding account that brings to life the intellectual excitement, ethical dilemmas, and fierce competitiveness of medical research. This new updated edition of the classic neurological mystery tale, “The Case of the Frozen Addicts,” illuminates how the solution to a baffling mystery of the brain’s chemistry opened a new frontier in medicine and restored life to people without hope. “It begins with a series of quixotic discoveries, escalates to providing possible solutions for one of humanity’s most intractable medical problems, and then catapults the reader into the center of America’s hottest political arena – abortion and fetal sanctity. Bravo! A brilliant read.” – Laurie Garrett, author of The Coming Plague “[Langston and Palfreman] weave a highly readable and spellbinding medical detective tale... It is as absorbing as a good mystery, as entertaining as an exciting novel, and as enlightening as a good biography.” – Stanley Fahn, New England Journal of Medicine “I could not put it down... it is the lives of the ‘frozen addicts’ themselves – and the fullness with which this is presented – which makes the whole thing overwhelming.” – Oliver Sacks