Author : Jonathan David Power
Publisher :
ISBN 13 :
Total Pages : 273 pages
Book Rating : 4.:/5 (885 download)
Book Synopsis Defining and Describing the Functional Network Organization of the Healthy Human Brain, with Observations on Development and Disease by : Jonathan David Power
Download or read book Defining and Describing the Functional Network Organization of the Healthy Human Brain, with Observations on Development and Disease written by Jonathan David Power and published by . This book was released on 2014 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis concerns the general functional organization of the healthy human brain. In contrast to studies of organization based on lesions or task-evoked activity, brain organization is studied using task-free measures of association between brain regions, namely resting state functional connectivity fMRI (RSFC). This technique measures relationships between brain regions using correlations in spontaneous, low-frequency BOLD signal, and is described in Chapter 1. In Chapter 2, we outline the general RSFC network structure of the healthy adult brain. In Chapter 3, we examine brain network structure for evidence of critical nodes in the system. In Chapter 4, as part of a collaboration, we test and confirm these predictions in a large neuropsychological database. Chapter 5 describes a novel motion-related artifact in resting state fMRI. Chapter 6 describes methods to eliminate artifactual influences of motion on cohort comparisons. Chapter 7 describes ongoing and future efforts building on the data presented in Chapters 2-6.