Ethical and Scientific Issues in Studying the Safety of Approved Drugs

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Publisher : National Academies Press
ISBN 13 : 0309218160
Total Pages : 292 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Ethical and Scientific Issues in Studying the Safety of Approved Drugs by : Institute of Medicine

Download or read book Ethical and Scientific Issues in Studying the Safety of Approved Drugs written by Institute of Medicine and published by National Academies Press. This book was released on 2012-07-30 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 48 percent of the population takes at least one prescription drug in a given month. Drugs provide great benefits to society by saving or improving lives. Many drugs are also associated with side effects or adverse events, some serious and some discovered only after the drug is on the market. The discovery of new adverse events in the postmarketing setting is part of the normal natural history of approved drugs, and timely identification and warning about drug risks are central to the mission of the Food and Drug Administration (FDA). Not all risks associated with a drug are known at the time of approval, because safety data are collected from studies that involve a relatively small number of human subjects during a relatively short period. Written in response to a request by the FDA, Ethical and Scientific Issues in Studying the Safety of Approved Drugs discusses ethical and informed consent issues in conducting studies in the postmarketing setting. It evaluates the strengths and weaknesses of various approaches to generate evidence about safety questions, and makes recommendations for appropriate followup studies and randomized clinical trials. The book provides guidance to the FDA on how it should factor in different kinds of evidence in its regulatory decisions. Ethical and Scientific Issues in Studying the Safety of Approved Drugs will be of interest to the pharmaceutical industry, patient advocates, researchers, and consumer groups.

Evidence-Based Management

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Publisher : Kogan Page Publishers
ISBN 13 : 074948375X
Total Pages : 393 pages
Book Rating : 4.7/5 (494 download)

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Book Synopsis Evidence-Based Management by : Eric Barends

Download or read book Evidence-Based Management written by Eric Barends and published by Kogan Page Publishers. This book was released on 2018-09-03 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decisions in businesses and organizations are too often based on fads, fashions and the success stories of famous CEOs. At the same time, traditional models and new cutting-edge solutions often fail to deliver on what they promise. This situation leaves managers, business leaders, consultants and policymakers with a profound challenge: how can we stay away from trends and quick fixes, and instead use valid and reliable evidence to support the organization? In response to this problem, evidence-based management has evolved with the goal of improving the quality of decision-making by using critically evaluated evidence from multiple sources - organizational data, professional expertise, stakeholder values and scientific literature. This book sets out and explains the specific skills needed to gather, understand and use evidence to make better-informed organizational decisions. Evidence-Based Management is a comprehensive guide that provides current and future managers, consultants and organizational leaders with the knowledge and practical skills to improve the quality and outcome of their decision-making. Online resources include case studies, exercises, lecture slides and further reading.

Educational Goods

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Publisher : University of Chicago Press
ISBN 13 : 022651417X
Total Pages : 201 pages
Book Rating : 4.2/5 (265 download)

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Book Synopsis Educational Goods by : Harry Brighouse

Download or read book Educational Goods written by Harry Brighouse and published by University of Chicago Press. This book was released on 2018-01-24 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, jointly authored by two distinguished philosophers and two prominent social scientists, has an ambitious aim: to improve decision-making in education policy. First they dive into the goals of education policy and explain the terms "educational goods" and "childhood goods," adding precision and clarity to the discussion of the distributive values that are essential for good decision-making about education. Then they provide a framework for individual decision-makers that enables them to combine values and evidence in the evaluation of educational policy options. Finally they delve into the particular policy issues of school finance, school accountability, and school choice, and they show how decision makers might approach them in the light of this decision-making framework. The authors are not advocated particular policy choices, however. The focus instead is a smart framework that will make it easier for policymakers (and readers) to identify and think through what they disagree with others about.

Evidence-based Decisions and Economics

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Publisher : John Wiley & Sons
ISBN 13 : 1444320408
Total Pages : 216 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Evidence-based Decisions and Economics by : Ian Shemilt

Download or read book Evidence-based Decisions and Economics written by Ian Shemilt and published by John Wiley & Sons. This book was released on 2011-09-22 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for evidence-based decisions that take account of botheffectiveness and economics is greater now than ever. Using casestudies and illustrative examples throughout the authors describehow the activities and outputs of evidence synthesis, systematicreview, economic analysis and decision-making interact within andacross different spheres of health and social policy and practice. Expanding on the first edition the book now covers approaches toevidence synthesis that combine economics and systematic reviewmethods in the applied fields of social welfare, education andcriminal justice, as well as health care. Written by economists andhealth services researchers closely involved in developingevidence-based policy and practice it showcases currentstate-of-the-art methodology and will be an invaluable read for allpolicy-makers and practitioners using evidence to inform decisions,analysts conducting research to support decisions and studentsdiscovering the need for evidence-based decisions to incorporateeconomic perspectives and evidence.

Evidence-based Decision Making

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Publisher :
ISBN 13 : 9780781765336
Total Pages : 0 pages
Book Rating : 4.7/5 (653 download)

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Book Synopsis Evidence-based Decision Making by : Jane L. Forrest

Download or read book Evidence-based Decision Making written by Jane L. Forrest and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise, hands-on text provides dental hygiene and dentistry students and practitioners with a method for making evidence-based decisions in practice. The book presents a step-by-step approach to mastering the five essential skills of evidence-based decision making%formulating patient-centered questions, searching for the appropriate evidence, critically appraising the evidence, applying the evidence to practice, and evaluating the process. Five Case Scenarios are used throughout the book in coordination with these skills and cover the broad areas of therapy/prevention, diagnosis, etiology/harm/causation, and prognosis. Each chapter has objectives, suggested activities, a quiz, critical thinking questions, and exercises. A companion Website includes online tutorials, additional cases, and links to additional resources. http://thepoint.lww.com/product/isbn/9780781765336

Evidence-Based Decision-Making

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Author :
Publisher : Routledge
ISBN 13 : 1351050060
Total Pages : 270 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Evidence-Based Decision-Making by : Andrew D. Banasiewicz

Download or read book Evidence-Based Decision-Making written by Andrew D. Banasiewicz and published by Routledge. This book was released on 2019-03-04 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-Based Decision-Making: How to Leverage Available Data and Avoid Cognitive Biases examines how a wide range of factual evidence, primarily derived from a variety of data available to organizations, can be used to improve the quality of business decision-making, by helping decision makers circumvent the various cognitive biases that adversely impact how we all think. The book is built on the following premise: During the past decade, the new ‘data world’ emerged, in which the rush to develop competencies around business analytics and data science can be characterized as nothing less than the new commercial arms race. The ever-expanding volume and variety of data are well known, as are the great advances in data processing/analytics, data visualization, and related information production-focused capabilities. Yet, comparatively little effort has been devoted to how the informational products of business analytics and data science are ‘consumed’ or used in the organizational decision-making processes, as the available evidence shows that only some of that information is used to drive some business decisions some of the time. Evidence-Based Decision-Making details an explicit process describing how the universe of available and applicable evidence, which includes organizational and other data, industry benchmarks, scientific studies, and professional experience, can be assessed, amalgamated, and funneled into an objective driver of key business decisions. Introducing key concepts in relation to data and evidence, and the history of evidence-based management, this new and extremely topical book will be essential reading for researchers and students of data analytics as well as those working in the private and public sectors, and in the voluntary sector.

Evidence Synthesis for Decision Making in Healthcare

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Publisher : John Wiley & Sons
ISBN 13 : 111830540X
Total Pages : 296 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Evidence Synthesis for Decision Making in Healthcare by : Nicky J. Welton

Download or read book Evidence Synthesis for Decision Making in Healthcare written by Nicky J. Welton and published by John Wiley & Sons. This book was released on 2012-04-12 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixed treatment comparisons, Markov models of disease progression, and epidemiology models). A comprehensive, coherent framework is adopted and estimated using Bayesian methods. Key features: A coherent approach to evidence synthesis from multiple sources. Focus is given to Bayesian methods for evidence synthesis that can be integrated within cost-effectiveness analyses in a probabilistic framework using Markov Chain Monte Carlo simulation. Provides methods to statistically combine evidence from a range of evidence structures. Emphasizes the importance of model critique and checking for evidence consistency. Presents numerous worked examples, exercises and solutions drawn from a variety of medical disciplines throughout the book. WinBUGS code is provided for all examples. Evidence Synthesis for Decision Making in Healthcare is intended for health economists, decision modelers, statisticians and others involved in evidence synthesis, health technology assessment, and economic evaluation of health technologies.

Evidence-Based Decision Making in Dentistry

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Publisher : Springer
ISBN 13 : 3319457330
Total Pages : 141 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Evidence-Based Decision Making in Dentistry by : Eyal Rosen

Download or read book Evidence-Based Decision Making in Dentistry written by Eyal Rosen and published by Springer. This book was released on 2017-01-05 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinically oriented book covers all aspects of the evidence-based decision making process in multidisciplinary management of the natural dentition. The book opens by clarifying the principles of evidence-based decision making and explaining how these principles should be applied in daily practice. Individual chapters then focus specifically, and in detail, on endodontic, periodontal, and prosthetic considerations, identifying aspects that need to be integrated into decision making and treatment planning. Evidence-based decision making with regard to preservation of the natural tooth versus extraction and implant placement is then discussed, and a concluding chapter examines likely future trends in dentistry and how they may affect clinical decision making. The authors include leading endodontists, periodontists, and prosthodontists. Given the multidisciplinary and comprehensive nature of the book, it will be relevant and interesting to the entire dental community.

Bridging the Evidence Gap in Obesity Prevention

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Publisher : National Academies Press
ISBN 13 : 0309149894
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bridging the Evidence Gap in Obesity Prevention by : Institute of Medicine

Download or read book Bridging the Evidence Gap in Obesity Prevention written by Institute of Medicine and published by National Academies Press. This book was released on 2010-12-24 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: To battle the obesity epidemic in America, health care professionals and policymakers need relevant, useful data on the effectiveness of obesity prevention policies and programs. Bridging the Evidence Gap in Obesity Prevention identifies a new approach to decision making and research on obesity prevention to use a systems perspective to gain a broader understanding of the context of obesity and the many factors that influence it.

Rational Diagnosis and Treatment

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Publisher : John Wiley & Sons
ISBN 13 : 9780470723685
Total Pages : 244 pages
Book Rating : 4.7/5 (236 download)

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Book Synopsis Rational Diagnosis and Treatment by : Peter Gøtzsche

Download or read book Rational Diagnosis and Treatment written by Peter Gøtzsche and published by John Wiley & Sons. This book was released on 2008-03-11 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fourth edition, Rational Diagnosis and Treatment: Evidence-Based Clinical Decision-Making is a unique book to look at evidence-based medicine and the difficulty of applying evidence from group studies to individual patients. The book analyses the successive stages of the decision process and deals with topics such as the examination of the patient, the reliability of clinical data, the logic of diagnosis, the fallacies of uncontrolled therapeutic experience and the need for randomised clinical trials and meta-analyses. It is the main theme of the book that, whenever possible, clinical decisions must be based on the evidence from clinical research, but the authors also explain the pitfalls of such research and the problems involved in applying evidence from groups of patients to the individual patient. For this new edition, the sections on placebo and meta-analysis and on alternative medicine have been thoroughly updated, and there is more focus on insufficient reporting of harms of interventions. The sections on different research designs describe advantages and limitations, and the increased medicalisation and the effects of cancer screening on health people are noted. A section on academic freedom when clinicians collaborate with industry and ghost authors is added. This essential reference work integrates the science and statistical approach of evidence-based medicine with the art and humanism of medical practice; distinguishing between data, sets of data, knowledge and wisdom, and their application. Such an intellectually challenging book is ideal for both medical students and doctors who require theoretical and practical clinical skills to help ensure that they apply theory in practice.

Evidence-Based Emergency Care

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Publisher : John Wiley & Sons
ISBN 13 : 0470657839
Total Pages : 502 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Evidence-Based Emergency Care by : Jesse M. Pines

Download or read book Evidence-Based Emergency Care written by Jesse M. Pines and published by John Wiley & Sons. This book was released on 2013-01-22 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book for emergency physicians and fellows training in emergency medicine provides evidence-based information on what diagnostic tests to ask for and when and how to use particular decision rules. The new edition builds on the success of the current book by modifying the presentation of the evidence, increasing the coverage, and updating the current information throughout.

Evidence-based Healthcare and Public Health

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Publisher : Elsevier Health Sciences
ISBN 13 : 044310123X
Total Pages : 453 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Evidence-based Healthcare and Public Health by : John Armstrong Muir Gray

Download or read book Evidence-based Healthcare and Public Health written by John Armstrong Muir Gray and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the demand for health services rises & the pressure on these services grows, decisions about the use of scarce resources are becoming even more difficult to make & more explicit. This text provides healthcare managers with the knowledge they need.

Decision Making in Health and Medicine

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Publisher : Cambridge University Press
ISBN 13 : 1107690471
Total Pages : 447 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Decision Making in Health and Medicine by : M. G. Myriam Hunink

Download or read book Decision Making in Health and Medicine written by M. G. Myriam Hunink and published by Cambridge University Press. This book was released on 2014-10-16 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide for everyone involved in medical decision making to plot a clear course through complex and conflicting benefits and risks.

Difficult Decisions in Trauma Surgery

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Publisher : Springer Nature
ISBN 13 : 3030816672
Total Pages : 443 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Difficult Decisions in Trauma Surgery by : Kenneth Wilson

Download or read book Difficult Decisions in Trauma Surgery written by Kenneth Wilson and published by Springer Nature. This book was released on 2021-10-29 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical guide to decision making within the realm of trauma surgery. Each chapter covers the ideal approach, rather than customary care, for the treatment of the chosen difficult decision or controversy. A broad range of topics are covered with particular attention given to resuscitation, wound management, thoracic and abdominal trauma, antimicrobial management, transplant considerations, vascular trauma, traumatic brain injury, pediatric trauma and ethics. Difficult Decisions in Trauma Surgery aims to help improve the treatment of trauma patients and is relevant to surgical trainees and practicing surgeons, and as well as medical professionals working within trauma medicine.

Evidence, Decision and Causality

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Publisher : Cambridge University Press
ISBN 13 : 9781316641545
Total Pages : 0 pages
Book Rating : 4.6/5 (415 download)

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Book Synopsis Evidence, Decision and Causality by : Arif Ahmed

Download or read book Evidence, Decision and Causality written by Arif Ahmed and published by Cambridge University Press. This book was released on 2017-02-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most philosophers agree that causal knowledge is essential to decision-making: agents should choose from the available options those that probably cause the outcomes that they want. This book argues against this theory and in favour of evidential or Bayesian decision theory, which emphasises the symptomatic value of options over their causal role. It examines a variety of settings, including economic theory, quantum mechanics and philosophical thought-experiments, where causal knowledge seems to make a practical difference. The arguments make novel use of machinery from other areas of philosophical inquiry, including first-person epistemology and the free will debate. The book also illustrates the applicability of decision theory itself to questions about the direction of time and the special epistemic status of agents.

Decision Making for the Environment

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Publisher : National Academies Press
ISBN 13 : 0309095409
Total Pages : 297 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Decision Making for the Environment by : National Research Council

Download or read book Decision Making for the Environment written by National Research Council and published by National Academies Press. This book was released on 2005-07-01 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the growing number, complexity, and importance of environmental problems come demands to include a full range of intellectual disciplines and scholarly traditions to help define and eventually manage such problems more effectively. Decision Making for the Environment: Social and Behavioral Science Research Priorities is the result of a 2-year effort by 12 social and behavioral scientists, scholars, and practitioners. The report sets research priorities for the social and behavioral sciences as they relate to several different kinds of environmental problems.

Smart Health Choices

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Author :
Publisher : Judy Irwig
ISBN 13 : 1905140177
Total Pages : 255 pages
Book Rating : 4.9/5 (51 download)

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Book Synopsis Smart Health Choices by : Les Irwig

Download or read book Smart Health Choices written by Les Irwig and published by Judy Irwig. This book was released on 2008 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day we make decisions about our health - some big and some small. What we eat, how we live and even where we live can affect our health. But how can we be sure that the advice we are given about these important matters is right for us? This book will provide you with the right tools for assessing health advice.