Data Analysis For Hyphenated Techniques

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Data Analysis for Hyphenated Techniques

Author : E.J. Karjalainen
Publisher : Elsevier
ISBN 13 : 0080544754
Total Pages : 481 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Data Analysis for Hyphenated Techniques by : E.J. Karjalainen

Download or read book Data Analysis for Hyphenated Techniques written by E.J. Karjalainen and published by Elsevier. This book was released on 1996-03-14 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a concrete set of working MATLAB programs, the book begins with a short program of snippets describing basic principles and proceeds to a complete application program filling a central analytical need: obtaining pure spectra from the observed overlapping spectra, with standard deviations for thesolutions obtained.The strength of the book is the open nature of the programs. All programs can be read, tested and modified by the user. The mathematical principles needed for the proper treatment of experimental data are thoroughly described. The first part of the book describes how data iscollected, converted and prepared for the actual deconvolution. Practical working algorithms such as the Savitzky-Golay smoothing method are emphasized. The reader can see how searches in spectral libraries can be greatly speeded up by proper formulation of the calculation. Basic signal processing is described by illustrative examples.The main part of the book describes the deconvolution of overlapping chromatographic peaks. Principle component analysis is described and used as a useful tool. The main emphasis is a discussion of a deconvolution method, OSCAR (Optimization by Stepwise Constraining of Alternating Regression), developed by the authors. The results can be validated as OSCAR calculates confidence intervals for the spectra and elution curves.For users who do not want to enter the programs by hand a separate CD-ROM is available. It contains the programs and extensive sample data files. The CD-ROM has instructional multimedia showing step by step how the programs are used for the problems in the book. The MATLAB programs and datafiles can be directly run on Windows® and Macintosh® computers having a MATLAB interpreter.

Mass Spectrometry

Author : Marek Smoluch
Publisher : John Wiley & Sons
ISBN 13 : 1119377307
Total Pages : 450 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Mass Spectrometry by : Marek Smoluch

Download or read book Mass Spectrometry written by Marek Smoluch and published by John Wiley & Sons. This book was released on 2019-07-11 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive description of mass spectrometry basics, applications, and perspectives Mass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry—from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS (paying special attention to various methodologies and data interpretation). It also contains a list of key terms for easier and faster understanding of the material by newcomers to the subject and test questions to assist lecturers. Knowing how crucial it is for young researchers to fully understand both the power of mass spectrometry and the importance of other complementary methodologies, Mass Spectrometry: An Applied Approach teaches that it should be used in conjunction with other techniques such as NMR, pharmacological tests, structural identification, molecular biology, in order to reveal the true function(s) of the identified molecule. Provides a description of mass spectrometry basics, applications and perspectives of the technique Oriented to a broad audience with limited or basic knowledge in mass spectrometry instrumentation, theory, and its applications in order to enhance their competence in this field Covers all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS with special attention to application of various methodologies and data interpretation Includes a list of key terms, and test questions, for easier and faster understanding of the material Mass Spectrometry: An Applied Approach is highly recommended for advanced students, young scientists, and anyone involved in a field that utilizes the technique.

Natural Products Isolation

Author : Satya D. Sarker
Publisher : Springer Science & Business Media
ISBN 13 : 1592599559
Total Pages : 518 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Natural Products Isolation by : Satya D. Sarker

Download or read book Natural Products Isolation written by Satya D. Sarker and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research. The first edition of Natural Products Isolation provided readers for the first time with some practical guidance in the process of extraction and isolation of natural products and was the result of Richard Cannell’s unique vision and tireless efforts. Unfortunately, Richard Cannell died in 1999 soon after completing the first edition. We are indebted to him and hope this new edition pays adequate tribute to his excellent work. The first edition laid down the “ground rules” and established the techniques available at the time. Since its publication in 1998, there have been significant developments in some areas in natural product isolation. To capture these developments, publication of a second edition is long overdue, and we believe it brings the work up to date while still covering many basic techniques known to save time and effort, and capable of results equivalent to those from more recent and expensive techniques.

Innovative Methods for Data Analysis in Analytical Chemistry Using Bayesian Statistics and Machine Learning

Author : Michael Tsegaye Woldegebriel
Publisher :
ISBN 13 : 9789462335394
Total Pages : 0 pages
Book Rating : 4.3/5 (353 download)

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Book Synopsis Innovative Methods for Data Analysis in Analytical Chemistry Using Bayesian Statistics and Machine Learning by : Michael Tsegaye Woldegebriel

Download or read book Innovative Methods for Data Analysis in Analytical Chemistry Using Bayesian Statistics and Machine Learning written by Michael Tsegaye Woldegebriel and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In analytical chemistry, rapid advancement in instrumentation, especially in high resolution mass-spectrometry is making a significant contribution for further developments of the field. As such, in separation science, nowadays, several hyphenated techniques have proven to be the state-of-the-art techniques for compound identification and characterization. Furthermore, these techniques have found several application areas including biomarker discovery, forensic investigation, food-health research and many others, mainly because of their high sensitivity, selectivity, and scope of analysis. As these techniques advance, the amount of data generated by the high resolution instruments has also increased tremendously, requiring a more sophisticated data analysis techniques to cope with the 'big data', and that can simultaneously extract and utilize the information. Taking into account the benefit of instrument coupling (i.e. LC-HRMS) for better separation and characterization of compounds has already been proven to be the most efficient approach, in the years to come, it can be speculated that even more sophisticated techniques such as liquid chromatography coupled to ion mobility spectrometry, and high resolution mass spectrometer (LC-IMS-HRMS) will be the dominating techniques, expanding the dimensionality and the complexity of the data produced. Thus, more than ever, it's crucial for data analysis techniques to advance a lot faster to manage the computational challenges, and so as to harness the full potential of these promising analytical techniques for routine analysis. The project of this thesis was a joint effort of industry partners involved in forensic, food-safety and material science, and had a common goal and interest in the development of robust data analysis techniques for compound screening.

Sample Preparation for Hyphenated Analytical Techniques

Author : J. M. Rosenfeld
Publisher : John Wiley & Sons
ISBN 13 : 9781405111065
Total Pages : 0 pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Sample Preparation for Hyphenated Analytical Techniques by : J. M. Rosenfeld

Download or read book Sample Preparation for Hyphenated Analytical Techniques written by J. M. Rosenfeld and published by John Wiley & Sons. This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written as an authoritative guide for analytical chemists in universities, research and testing organisations, and the pharmaceutical, agrochemical and speciality chemicals industries, Sample Preparation for Hyphenated Analytical Techniques reviews the sample preparation chemistry that has enabled the present sensitivity, specificity and high throughput available across a range of hyphenated analytical techniques. Furthermore, it illustrates the successful utilization of existing sample preparation methodologies in various analytical applications, and points to areas where new methodologies are required. By dealing with issues wider than those generally found in review papers, this book provides insights that are not available by searching the literature for papers on a specific topic.

Analytical Techniques in Biosciences

Author : Chukwuebuka Egbuna
Publisher : Academic Press
ISBN 13 : 0128227990
Total Pages : 302 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Analytical Techniques in Biosciences by : Chukwuebuka Egbuna

Download or read book Analytical Techniques in Biosciences written by Chukwuebuka Egbuna and published by Academic Press. This book was released on 2021-10-21 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analytical Techniques in Biosciences: From Basics to Applications presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay protocols. Other chapters detail microbial techniques, statistical methods, computational modeling, and immunology and immunochemistry. The book draws from experts from key institutions around the globe, who have simplified the chapters in a way that will be useful to early-stage researchers as well as advanced scientists. It is also carefully structured and integrated sequentially to aid flow, consistency, and continuity. This is a must-have reference for graduate students and researchers in the field of biosciences. Presents basic analytical protocols and sample-preparation guidelines Details the various analytical techniques, including centrifugation, spectrometry, chromatography, and titrimetry Describes advanced techniques such as hyphenated techniques, electroanalytical techniques, and the application of biosensors in biomedical research Presents biostatistical tools and methods and basic computational models in biosciences

Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research

Author : Jerzy Silberring
Publisher : John Wiley & Sons
ISBN 13 : 9780471354932
Total Pages : 576 pages
Book Rating : 4.3/5 (549 download)

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Book Synopsis Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research by : Jerzy Silberring

Download or read book Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research written by Jerzy Silberring and published by John Wiley & Sons. This book was released on 2002-05-02 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first authoritative guide to the application of this vital analytical technique Mass spectrometry is a powerful analytical technique that is used to identify unknown compounds, to quantify known materials, and to elucidate the structural and chemical properties of molecules. In analyzing the effects of experimental drugs on the brain, it is the sole technique for identifying the presence and structure of neuropeptides-substances that indicate the effect of the drug. Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research specifically explains how to apply the technology to this process. Because the book is written by mass spectrometry users, as opposed to mass spectrometrists, the focus remains on practical applications of the technique. The authors demonstrate how mass spectrometry works, how to apply the technique to research, which types of instrumentation should be used for particular requirements, and how to plan experiments. Readers will learn why mass spectrometry provides more outcome features than other techniques in neuropeptide analysis, including simultaneous detection, identification of substances present in mixtures, and sequence information even when the residues are modified, blocked, or unusual. Among the chapters in this comprehensive text are: * Sequencing of Peptides by Nanospray Mass Spectrometry * Laser-Machined Microdevices for Mass Spectrometry * Electron Capture Dissociation of Peptides * Synthesis of Combinatorial Peptide Libraries * Analysis of Tissues That Reflect Nervous System Disease Doctoral students, researchers, and industry professionals in pharmacology, chemistry, biochemistry/biotechnology, and medicine will find Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research to be an indispensable starting point for understanding peptides, their function, and identification.

Technology in Forensic Science

Author : Deepak Rawtani
Publisher : John Wiley & Sons
ISBN 13 : 3527347623
Total Pages : 412 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Technology in Forensic Science by : Deepak Rawtani

Download or read book Technology in Forensic Science written by Deepak Rawtani and published by John Wiley & Sons. This book was released on 2020-11-02 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book "Technology in Forensic Science" provides an integrated approach by reviewing the usage of modern forensic tools as well as the methods for interpretation of the results. Starting with best practices on sample taking, the book then reviews analytical methods such as high-resolution microscopy and chromatography, biometric approaches, and advanced sensor technology as well as emerging technologies such as nanotechnology and taggant technology. It concludes with an outlook to emerging methods such as AI-based approaches to forensic investigations.

Directory of Hyphenated Techniques

Author : Zdeněk Deyl
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Directory of Hyphenated Techniques by : Zdeněk Deyl

Download or read book Directory of Hyphenated Techniques written by Zdeněk Deyl and published by Elsevier Publishing Company. This book was released on 1994 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This directory of researchers in hyphenated techniques contains the names and addresses of leading scientists in this developing field and specifies their main interests in developing and/or applying their technique. A geographical index shows what techniques are used in each country.

Fundamentals and Applications of Multiway Data Analysis

Author : Alejandro Olivieri
Publisher : Elsevier
ISBN 13 : 0443132623
Total Pages : 710 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Fundamentals and Applications of Multiway Data Analysis by : Alejandro Olivieri

Download or read book Fundamentals and Applications of Multiway Data Analysis written by Alejandro Olivieri and published by Elsevier. This book was released on 2024-01-19 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals and Applications of Multiway Data Analysis provides comprehensive coverage of the main aspects of multiway analysis, including selected applications that can resolve complex analytical chemistry problems. This book follows on from Fundamentals and Analytical Applications of Multiway Calibration, (2015) by addressing new theoretical analysis and applications on subjects beyond multiway calibration and devoted to the analysis of multiway data for other purposes. Specifically, this new volume presents researchers a set of effective tools they can use to obtain the maximum information from instrumental data. This book includes the most advanced techniques, methods and algorithms related to multiway modelling for solving calibration and classification tasks, and the way they can be applied. This book collects contributions from a selected number of well-known and active chemometric research groups across the world, each covering one or more subjects where their expertise is recognized and appreciated. - Includes chapters written by renowned international authors, all currently active in the subject field - Presents coverage of all the main aspects of multi-way analytical data analysis, concerning the two main areas of interest: data generation and algorithmic models for data processing - Provides up-to-date material with reference to current literature on the subject

Practical Data Analysis in Chemistry

Author : Marcel Maeder
Publisher : Elsevier
ISBN 13 : 0080548830
Total Pages : 341 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Practical Data Analysis in Chemistry by : Marcel Maeder

Download or read book Practical Data Analysis in Chemistry written by Marcel Maeder and published by Elsevier. This book was released on 2007-08-10 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: The majority of modern instruments are computerised and provide incredible amounts of data. Methods that take advantage of the flood of data are now available; importantly they do not emulate 'graph paper analyses' on the computer. Modern computational methods are able to give us insights into data, but analysis or data fitting in chemistry requires the quantitative understanding of chemical processes. The results of this analysis allows the modelling and prediction of processes under new conditions, therefore saving on extensive experimentation. Practical Data Analysis in Chemistry exemplifies every aspect of theory applicable to data analysis using a short program in a Matlab or Excel spreadsheet, enabling the reader to study the programs, play with them and observe what happens. Suitable data are generated for each example in short routines, this ensuring a clear understanding of the data structure. Chapter 2 includes a brief introduction to matrix algebra and its implementation in Matlab and Excel while Chapter 3 covers the theory required for the modelling of chemical processes. This is followed by an introduction to linear and non-linear least-squares fitting, each demonstrated with typical applications. Finally Chapter 5 comprises a collection of several methods for model-free data analyses.* Includes a solid introduction to the simulation of equilibrium processes and the simulation of complex kinetic processes.* Provides examples of routines that are easily adapted to the processes investigated by the reader* 'Model-based' analysis (linear and non-linear regression) and 'model-free' analysis are covered

New Generation Green Solvents for Separation and Preconcentration of Organic and Inorganic Species

Author : Mustafa Soylak
Publisher : Elsevier
ISBN 13 : 0128185708
Total Pages : 482 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis New Generation Green Solvents for Separation and Preconcentration of Organic and Inorganic Species by : Mustafa Soylak

Download or read book New Generation Green Solvents for Separation and Preconcentration of Organic and Inorganic Species written by Mustafa Soylak and published by Elsevier. This book was released on 2020-04-07 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Generation Green Solvents for Separation and Preconcentration of Organic and Inorganic Species is designed to help researchers and students understand the production and application of new generation green solvents in separation- and preconcentration-based analytical methods. Beginning with the historical background and milestones in the development of analytical instrumentation, the book goes on to give a detailed overview of the most up-to-date uses of green solvents in sample preparation. Using a wealth of examples, it compares old and new extraction procedures and explores the many applications of new generation green solvents. Practical, easy-to-follow experiments are used to illustrate the key concepts. This practical guide helps to promote the use of safer, more sustainable solvents in analytical chemistry and beyond for environmental scientists, researchers in pharmaceutical and biotech industries, and students in analytical chemistry. - Covers the basic analytical theory essential for understanding extraction- and microextraction-based separation and preconcentration methods - Explains combination use of new generation solvents with various detection systems, including UV-VIS, ICP-MS, HPLC, LC-MS, GC-MS, and LC-MS/MS - Emphasizes trace chemical component separation, preconcentration and analysis

Data Analysis and Signal Processing in Chromatography

Author : A. Felinger
Publisher : Elsevier
ISBN 13 : 0080525563
Total Pages : 427 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Data Analysis and Signal Processing in Chromatography by : A. Felinger

Download or read book Data Analysis and Signal Processing in Chromatography written by A. Felinger and published by Elsevier. This book was released on 1998-05-19 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of the numerical data analysis and signal treatment techniques that are used in chromatography and related separation techniques. Emphasis is given to the description of the symmetrical and asymmetrical chromatographic peak shape models. Both theoretical and empirical models are discussed.The fundamentals of data acquisition, types and effect of baseline noise, and methods of improving the signal-to-noise ratio (either in time or in frequency and wavelet domain) are thoroughly discussed. Resolution enhancement techniques, such as curve fitting, deconvolution by Fourier and wavelet transforms, iterative deconvolution, Kalman filtering and multivariate methods of curve resolution are all discussed with several chromatographic examples. Quantitative analysis by peak area of peak height measurement, the precision and accuracy of the quantitation of stand-alone or overlapping and symmetrical or asymmetrical peaks are treated. In a separate chapter, guidelines are given for the use of transform techniques for the analysis of chromatograms. A statistical description of peak overlap is given in the final chapters. Since the concept of resolution has to be reconsidered when one separates complex mixtures, the problem of resolution and overlap is quantitatively discussed by means of statistical methods, and by using Fourier analysis of the complex chromatogram.Features of this book• The ultimate source of numerical techniques to enhance chromatographic data• Gives a detailed description of signal and resolution enhancement techniques in a manner applicable for enhancing not only chromatography, but also spectroscopic and other analytical signals• The first book with a thorough overview of the statistics of peak overlap.This is the first volume to encompass both the simple and more sophisticated methods for the numerical treatment of chromatograms. It is, therefore, the fundamental resource of numerical analysis methods for every analyst.

Encyclopedia of Chromatography

Author : Jack Cazes
Publisher : CRC Press
ISBN 13 : 1439870675
Total Pages : 2968 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Encyclopedia of Chromatography by : Jack Cazes

Download or read book Encyclopedia of Chromatography written by Jack Cazes and published by CRC Press. This book was released on 2009-10-12 with total page 2968 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and expanded, this third edition offers illustrative tables and figures to clarify technical points in the articles and provides a valuable, reader-friendly reference for all those who employ chromatographic methods for analysis of complex mixtures of substances. An authoritative source of information, this introductory guide to specific chromatographic techniques and theory discusses the relevant science and technology, offering key references for analyzing specific chemicals and applications in industry and focusing on emerging technologies and uses.

Scientific Data Ranking Methods

Author :
Publisher : Elsevier
ISBN 13 : 0080931936
Total Pages : 225 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Scientific Data Ranking Methods by :

Download or read book Scientific Data Ranking Methods written by and published by Elsevier. This book was released on 2008-11-17 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the basic mathematics of ranking methods through a didactic approach and the integration of relevant applications. Ranking methods can be applied in several different fields, including decision support, toxicology, environmental problems, proteomics and genomics, analytical chemistry, food chemistry, and QSAR.. Covers a wide range of applications, from the environment and toxicology to DNA sequencing. Incorporates contributions from renowned experts in the field. Meets the increasing demand for literature concerned with ranking methods and their applications

On-line LC-NMR and Related Techniques

Author : Klaus Albert
Publisher : John Wiley & Sons
ISBN 13 : 0470854812
Total Pages : 306 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis On-line LC-NMR and Related Techniques by : Klaus Albert

Download or read book On-line LC-NMR and Related Techniques written by Klaus Albert and published by John Wiley & Sons. This book was released on 2003-02-14 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive overview of the basis and the current applications of LC-NMR and related techniques. It deals with the practical aspects of the hardware and software set-up for a successful performance of on-line coupling experiments. It covers the solution of real-word problems from the fields of biomedical, pharmaceutical and environmental studies as well as the analysis of natural products and polymeric compounds. Thus guidelines for an efficient application of the powerful hyphenated technique LC-NMR in combination with LC-MS are presented. Besides LC-NMR, important techniques such as the on-line coupling of gel permeation chromatography and supercritical fluid chromatography, together with 1H NMR spectroscopy, are described in detail. Fascinating further aspects, such as the application of capillary separation techniques either in the single or parallel detection mode, together with the possibilities of direct 13C monitoring of chromatographic events, are also discussed. Key features include: * Up-to-date information on the theoretical and experimental methodology * Coverage of applications in biomedical, pharmaceutical and natural product analysis, as well as environmental polymer and related hyphenated techniques * Information appropriate for researchers in organic, pharmaceutical and medical chemistry Overall, this book is a requirement for all researchers and staff members dealing with structure elucidation problems in separation science.

Practical Gas Chromatography

Author : Katja Dettmer-Wilde
Publisher : Springer
ISBN 13 : 3642546404
Total Pages : 904 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Practical Gas Chromatography by : Katja Dettmer-Wilde

Download or read book Practical Gas Chromatography written by Katja Dettmer-Wilde and published by Springer. This book was released on 2014-11-05 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gas chromatography continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors. Specialized techniques from all aspects of GC are introduced ranging from sample preparation, solvent-free injection techniques, and pyrolysis GC, to separation including fast GC and comprehensive GCxGC and finally detection, such as GC-MS and element-specific detection. Various fields of application such as enantiomer, food, flavor and fragrance analysis, physicochemical measurements, forensic toxicology, and clinical analysis are discussed as well as cutting-edge application in metabolomics is covered.