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Dancing With My Cancer Demon All The Way To A Nih Nci Immunotherapy Clinical Trial B W
Download Dancing With My Cancer Demon All The Way To A Nih Nci Immunotherapy Clinical Trial B W full books in PDF, epub, and Kindle. Read online Dancing With My Cancer Demon All The Way To A Nih Nci Immunotherapy Clinical Trial B W ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Handbook of Anticancer Pharmacokinetics and Pharmacodynamics by : William Figg
Download or read book Handbook of Anticancer Pharmacokinetics and Pharmacodynamics written by William Figg and published by Humana Press. This book was released on 2004-03-26 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.
Download or read book "Cancer" written by and published by Lulu.com. This book was released on with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book EBMT HANDBOOK written by and published by . This book was released on 2025 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis by : Padma V. Devarajan
Download or read book Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis written by Padma V. Devarajan and published by Springer Nature. This book was released on 2019-11-09 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.
Book Synopsis Science of Ashwagandha: Preventive and Therapeutic Potentials by : Sunil C. Kaul
Download or read book Science of Ashwagandha: Preventive and Therapeutic Potentials written by Sunil C. Kaul and published by Springer. This book was released on 2017-09-13 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapidly increasing aging population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the modern society. The complex etiologies and pathologies cause major challenges to disease treatment. On the other hand, several herbs are known for their health-caring and disease-curing activities. Ashwagandha, a popular herb in Indian traditional home medicine, Ayurveda, has gathered increasing recognition in recent years when the chemically synthesized drugs for single target therapies showed limited success and adverse toxic effects. Ashwagandha is known as a powerful adaptogen and trusted to enhance function of the brain, reproductive system, cell-mediated immunity and increase the body's defense against disease, and possess anti-inflammatory, anticancer and anti-arthritic activities. In this book, for the first time, we provide a complete portrait on scientific understanding of the effects of Ashwagandha and its active principles for a variety of preventive and therapeutic activities.
Book Synopsis Immune Mediated Diseases by : Michael R Shurin
Download or read book Immune Mediated Diseases written by Michael R Shurin and published by Springer Science & Business Media. This book was released on 2007-09-23 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; Moscow, Russia) who were eager to share some of the academic and clinical enthusiasm that defines the IMD meetings. The goal of the International Immune-Mediated Diseases: From Theory to Therapy (IMD) Congress is to bring the world’s best immunologists and clinicians to Moscow.
Book Synopsis Characterization of Nanoparticles Intended for Drug Delivery by :
Download or read book Characterization of Nanoparticles Intended for Drug Delivery written by and published by Springer. This book was released on 2011-08-14 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Environmental Biotechnology Volume 4 by : K. M. Gothandam
Download or read book Environmental Biotechnology Volume 4 written by K. M. Gothandam and published by Springer Nature. This book was released on 2021-09-24 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the production of bioplastic from various raw materials and recycling wastewater into useful bioproducts by bacteria. In addition, it also addresses the recent advancement in pest control in rice plants, different methods to analyse genotoxicity on soil samples and the effect of phytocompounds on acrylamide-induced toxicity in Drosophilla. Interestingly, this book also discusses mesoporous silica nanoparticles' role as nanocarrier material for inhibiting the cancer cell, especially breast cancer and various biotechnological applications of marine fungal exopolysaccharides.
Book Synopsis Therapeutic Nuclear Medicine by : Richard P. Baum
Download or read book Therapeutic Nuclear Medicine written by Richard P. Baum and published by Springer. This book was released on 2014-08-16 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.
Book Synopsis Principles and Concepts of Behavioral Medicine by : Edwin B. Fisher
Download or read book Principles and Concepts of Behavioral Medicine written by Edwin B. Fisher and published by Springer. This book was released on 2018-10-08 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Concepts of Behavioral Medicine A Global Handbook Edwin B. Fisher, Linda D. Cameron, Alan J. Christensen, Ulrike Ehlert, Brian Oldenburg, Frank J. Snoek and Yan Guo This definitive handbook brings together an international array of experts to present the broad, cells-to-society perspectives of behavioral medicine that complement conventional models of health, health care, and prevention. In addition to applications to assessment, diagnosis, intervention, and management, contributors offer innovative prevention and health promotion strategies informed by current knowledge of the mechanisms and pathways of behavior change. Its range of conceptual and practical topics illustrates the central role of behavior in health at the individual, family, community, and population levels, and its increasing importance to person-centered care. The broad perspectives on risk (e.g., stress, lifestyle), management issues (e.g., adherence, social support), and overarching concerns (e.g., inequities, health policy) makes this reference uniquely global as it addresses the following core areas: · The range of relationships and pathways between behavior and health. · Knowing in behavioral medicine; epistemic foundations. · Key influences on behavior and the relationships among behavior, health, and illness. · Approaches to changing behavior related to health. · Key areas of application in prevention and disease management. · Interventions to improve quality of life. · The contexts of behavioral medicine science and practice. Principles and Concepts of Behavioral Medicine opens out the contemporary world of behavior and health to enhance the work of behavioral medicine specialists, health psychologists, public health professionals and policymakers, as well as physicians, nurses, social workers and those in many other fields of health practice around the world.
Book Synopsis Mucosal Delivery of Drugs and Biologics in Nanoparticles by : Pavan Muttil
Download or read book Mucosal Delivery of Drugs and Biologics in Nanoparticles written by Pavan Muttil and published by Springer Nature. This book was released on 2020-03-18 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has revolutionized the approach to designing and developing novel drug delivery systems. The last two decades have seen a great interest in the use of nanotechnology to offer efficient ways of delivering new and existing drugs and macromolecules. The focus of this book is the application of nanotechnology to deliver drugs and biological agents by the mucosal routes of administration i.e. nasal, pulmonary, buccal, and oral routes. It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery. The emphasis is on the use of nanoparticles in treating various cancers and infectious diseases. It broadens the use of nanoparticles by including biologics, including vaccines and immunotherapies, apart from drugs and acknowledges the concerns around the potential toxicity of nanoparticles to the host; several chapters will discuss the biodistribution of these nanoparticles when mucosal routes of administration are employed. Further, the interaction of nanoparticles with the host’s immune cells is discussed. Moreover, it reviews the regulatory aspects of nanotechnology in product development, especially when delivered by the mucosal route of administration. Lastly, discusses the challenges and opportunities to manufacture nanoparticles on an industrial scale. This book is the first of its kind to focus on the design, development and delivery of nanoparticles when administered by different mucosal routes.
Author :Antonio Llombart Bosch Publisher :Springer Science & Business Media ISBN 13 :9780306477621 Total Pages :312 pages Book Rating :4.4/5 (776 download)
Book Synopsis New Trends in Cancer for the 21st Century by : Antonio Llombart Bosch
Download or read book New Trends in Cancer for the 21st Century written by Antonio Llombart Bosch and published by Springer Science & Business Media. This book was released on 2003 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest advances in cancer research include basic research and its derived diagnostic, clinical and therapeutic applications. The book New Trends in Cancer for the 21st Century is written by individuals such as: molecular biologists whose tasks are, after sequencing the human genome, to decipher those new genes and pathways involved in the carcinogenesis process; clinical and molecular pathologists, who apply these discoveries for the molecular diagnosis and characterization of the tumour; and clinical oncologists, who treat patients. Pharmacogenetics introduces new perspectives in the translational fields with the design of drugs against specific targets, which are in clinical trials phases in 2003. Several organizations such as the EORTC (European Organization for Research and Treatment of Cancer) and the OECI (Organization of European Cancer Institutes) and comprehensive cancer centres play a crucial role in focusing cancer research on all these areas.
Book Synopsis Approaching Complex Diseases by : Mariano Bizzarri
Download or read book Approaching Complex Diseases written by Mariano Bizzarri and published by Springer Nature. This book was released on 2020-04-17 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
Book Synopsis Application of Thermodynamics to Biological and Materials Science by : Mizutani Tadashi
Download or read book Application of Thermodynamics to Biological and Materials Science written by Mizutani Tadashi and published by BoD – Books on Demand. This book was released on 2011-01-14 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress of thermodynamics has been stimulated by the findings of a variety of fields of science and technology. The principles of thermodynamics are so general that the application is widespread to such fields as solid state physics, chemistry, biology, astronomical science, materials science, and chemical engineering. The contents of this book should be of help to many scientists and engineers.
Book Synopsis Managing Cancer and Living Meaningfully by : Gary Rodin
Download or read book Managing Cancer and Living Meaningfully written by Gary Rodin and published by Oxford University Press. This book was released on 2021-04-27 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing Cancer and Living Meaningfully provides valuable insight into the experience of patients and families living with advanced cancer and describes a novel psychotherapeutic approach to help them live meaningfully, while also facing the threat of mortality. Managing Cancer and Living Meaningfully, also known by the acronym CALM, is a brief supportive-expressive intervention that can be delivered by a wide range of trained healthcare providers as part of cancer care or early palliative care. The authors provide an overview of the clinical experience and research that led to the development of CALM, a clear description of the intervention, and a manualized guide to aid in its delivery. Situated in the context of early palliative care, this text is destined to be become essential reading for healthcare professionals engaged in providing psychological support to patients and their families who face the practical and profound problems of advanced disease.
Download or read book Breast Disease written by Adnan Aydiner and published by . This book was released on 2019 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first of two fully updated volumes provides an in-depth account of breast disease characteristics, imaging and diagnosis. Covering from breast anatomy and tumor biology to benign and malignant lesions this is an indispensable companion for breast specialists, medical oncologists, radiologists and pathologists. The new edition contains chapters covering nuclear medicine iand a chapter explaining biostatistical and epidemiological terms and has been updated to reflect the latest changes in biomarkers and cancer staging. The book explores topics such as epidemiology, risk factors, pathological evaluation of tumors and biopsy techniques. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into pathological and epidemiological aspects of breast disease. Covering both theoretical and practical aspects of breast cancer this is a highly informative and carefully presented book which will appeal to an international audience of breast cancer practitioners.
Book Synopsis Healthy Aging by : Virginia Burggraf
Download or read book Healthy Aging written by Virginia Burggraf and published by . This book was released on 2014 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an evidence-based approach for helping older adults maintain healthy lifestyles, adapt to normal age-related changes, and manage acute and chronic illnesses. This text, divided into chronic illness both physical and emotional, covers only the most common illnesses of older adults and incorporates the holistic framework that comprises geriatric care in partnership with physicians, gerontologists and nurses.
