Dancing with My Cancer Demon: All the Way to a NIH/NCI Immunotherapy Clinical Trial

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Publisher : Lulu.com
ISBN 13 : 1365529592
Total Pages : 365 pages
Book Rating : 4.3/5 (655 download)

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Book Synopsis Dancing with My Cancer Demon: All the Way to a NIH/NCI Immunotherapy Clinical Trial by : Clark B. Hanmer, MD

Download or read book Dancing with My Cancer Demon: All the Way to a NIH/NCI Immunotherapy Clinical Trial written by Clark B. Hanmer, MD and published by Lulu.com. This book was released on 2016-11-12 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is not your typical death and dying, search for the meaning of life, cancer story. More like a dance lesson. I'm a family doc who flipped to Stage-4 cancer overnight. Making my way with this terrible problem, I've managed to survive a year, learning a lot in the process. This is my journal, with commentary from friends, written as events unfolded. I offer it for others to find insights and make their dance a little easier. Subjects explored: CANCER: the emotional roller coaster, managing well-wishers, keeping everyone up to date, sorting treatment options and clinical trials. HEALTH CARE: find good doctors, manage your medical record, rebut insurance denials, and find an advocate to assist. DOCTORING: my rural practice stories explore what it takes to become a wise physician, by learning from patients. SURVIVING: Resilience, faith, personal choice, palliative care, and advanced directives. LIVING: Reconnecting and having some fun. Making the best of the time we have left.

Challenging Cases in Clinical Research Ethics

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Publisher : CRC Press
ISBN 13 : 1000989879
Total Pages : 518 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Challenging Cases in Clinical Research Ethics by : Benjamin S Wilfond

Download or read book Challenging Cases in Clinical Research Ethics written by Benjamin S Wilfond and published by CRC Press. This book was released on 2023-11-22 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical research ethics consultation has emerged in the last 15 years as a service to those involved in the conduct of clinical research who face challenging issues for which more than one course of action may be justified. To respond to a growing field and need for opportunities to share knowledge and experience, the Clinical Research Ethics Consultation Collaborative, established in 2014, holds monthly webinars for its 90 members to present their most challenging cases to each other and engage in substantive discussion. Every year, the group selects the four most interesting cases with accompanying commentaries for publication in the American Journal of Bioethics. This timely book brings together these cases and commentaries under a range of common themes for the first time, creating a permanent collection in book format that encourages and supports readers to gain a better understanding of the ethical challenges that they may face, and providing them with a convenient and reflective resource to reference in their own deliberations. Key Features: • Comprehensive collection of cases and commentaries, chosen to reflect the range of issues faced by clinical researchers and oversight committees and illustrate the diversity of analysis that can arise • Supplemented by short introductions to each section • Focus on ethical rather than regulatory issues • Essential reading for graduate students in bioethics and post-doctoral bioethics fellows, and useful for all participants in training grants that are funded by either NIH or NSF Presenting challenging cases to stimulate reflection, the book provides invaluable guidance to clinicians in training and in practice and to investigators, bioethics consultants, regulators, and oversight bodies.

Childhood Leukemia

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Publisher : Childhood Cancer Guides
ISBN 13 : 1941089097
Total Pages : 529 pages
Book Rating : 4.9/5 (41 download)

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Book Synopsis Childhood Leukemia by : Nancy Keene

Download or read book Childhood Leukemia written by Nancy Keene and published by Childhood Cancer Guides. This book was released on 2014-03-01 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 3,300 children are diagnosed with leukemia in the United States each year. The illness and its treatment can have a devastating effect on family, friends, schoolmates, and the larger community. This newly updated edition of Childhood Leukemia contains the information and support parents need during this difficult time. Author Nancy Keene provides parents and family members with: • Updates on treatment, including stem cell transplants, information about tailoring drugs dosages to children’s genetic profiles, and new methods for dealing with side effects. • Practical advice on how to cope with medical procedures, hospitalization, school, family, and financial issues. • Suggestion son ways to form a partnership with the medical team. • Stories from family members who have coped with leukemia and its treatments. • Updated resources for medical information, emotional support, and financial assistance. • A pull out medical record-keeper. Parents who read this book will find understandable medical infomation, obtain advice that eases their daily life, and feel empowered to be strong advocates for their child.

"Cancer"

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Author :
Publisher : Lulu.com
ISBN 13 : 1105103668
Total Pages : 188 pages
Book Rating : 4.1/5 (51 download)

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Book Synopsis "Cancer" by :

Download or read book "Cancer" written by and published by Lulu.com. This book was released on with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advancing the Science of Cancer in Latinos

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Publisher : Springer Nature
ISBN 13 : 303029286X
Total Pages : 320 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Advancing the Science of Cancer in Latinos by : Amelie G. Ramirez

Download or read book Advancing the Science of Cancer in Latinos written by Amelie G. Ramirez and published by Springer Nature. This book was released on 2019-11-21 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Topics included among the chapters: Colorectal cancer disparities in Latinos: Genes vs. Environment Breast cancer risk and mortality in women of Latin American origin Differential cancer risk in Latinos: The role of diet Overcoming barriers for Latinos on cancer clinical trials Es tiempo: Engaging Latinas in cervical cancer research Emerging policies in U.S. health care Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.

Biologics, Biosimilars, and Biobetters

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Publisher : John Wiley & Sons
ISBN 13 : 1119564654
Total Pages : 328 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Biologics, Biosimilars, and Biobetters by : Iqbal Ramzan

Download or read book Biologics, Biosimilars, and Biobetters written by Iqbal Ramzan and published by John Wiley & Sons. This book was released on 2021-02-03 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive primer and reference, this book provides pharmacists and health practitioners the relevant science and policy concepts behind biologics, biosimilars, and biobetters from a practical and clinical perspective. Explains what pharmacists need to discuss the equivalence, efficacy, safety, and risks of biosimilars with physicians, health practitioners, and patients about Guides regulators on pragmatic approaches to dealing with these drugs in the context of rapidly evolving scientific and clinical evidence Balances scientific information on complex drugs with practical information, such as a checklist for pharmacists

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

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Publisher : Humana Press
ISBN 13 : 9781588291776
Total Pages : 623 pages
Book Rating : 4.2/5 (917 download)

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Book Synopsis Handbook of Anticancer Pharmacokinetics and Pharmacodynamics by : William Figg

Download or read book Handbook of Anticancer Pharmacokinetics and Pharmacodynamics written by William Figg and published by Humana Press. This book was released on 2004-03-26 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.

Palliative Care for Chronic Cancer Patients in the Community

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Publisher : Springer Nature
ISBN 13 : 3030545261
Total Pages : 566 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Palliative Care for Chronic Cancer Patients in the Community by : Michael Silbermann

Download or read book Palliative Care for Chronic Cancer Patients in the Community written by Michael Silbermann and published by Springer Nature. This book was released on 2020-10-29 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new global cancer data suggests that the global burden has risen to 18.1 million new cases per year and 9.6 million cancer deaths per year. A number of factors appear to be driving this increase, in particular, a growing and aging global population and an increase of exposure to cancer risk factors linked to social and economic development. For rapidly-growing economies, the data suggests a shift from poverty- or infection-related cancers to those associated with lifestyles more typical in industrialized countries. There is still large geographical diversity in cancer occurrence and variations in the magnitude and profile of the disease between and within world regions. There are specific types of cancer that dominate globally: lung, female breast and colorectal cancer, and the regional variations in common cancer types signal the extent to which societal, economic and lifestyle changes interplay to deferentially impact on the profile of this most complex group of diseases. Unfortunately, despite advances in cancer care, a significant proportion of patients at home, experience sub-optimal outcomes. Barriers to successful treatment outcomes include, but are not limited to: access to oncologists in the primary health centers, non-adherence, lack of experienced oncology and palliative care nurses in the community, inadequate monitoring and the lack of training of family and pediatric physicians. Telemedicine approaches, including telephone triage/education, telemonitoring, teleconsultation and status tracking through mobile applications, have shown promise in further improving outcomes, in particular for chronic cancer patients following their hospitalization. Lessons can be learned from existing hospices in North America, the United Kingdom, Australia, Centers of Excellence in African (Uganda) and modern community services in India (Kerala). An important goal of this book is to describe and encourage professionals to develop new community programs in palliative care, which include training and empowering physicians and nurses in the community on the principles of palliative care. The Middle East Cancer Consortium (MECC) together with the American Society of Clinical Oncology (ASCO) and the American Oncology Nursing Society (ONS) have conducted multiple courses ranging from basic palliative care to more specialized training in palliative care for multiple nationalities in Europe, Asia and Africa. Our experience clearly indicates that, to promote such activities, one needs strong leadership and confirmed political will to support the endeavor. The new book will emphasize the importance of having a core of multiple stakeholders including community leaders, government, NGOs and media to be actively involved in advocating for the cause and generating public awareness. This text will provide the reader with a comprehensive understanding of the outside-of-the-hospital treatment of cancer patients by medical, paramedical and volunteer personnel. In doing so, this text will encourage the creation of new palliative care services improving upon the existing ones and stimulate further research in this field. Part 1 of the text will begin with an overview of the current state of affairs of services provided to cancer patients while being cared for by primary health centers. It will also review the current literature regarding medical and psychological-based therapy options in the community for cancer patients at different stages of their disease. Part 2 will address the unique role of the community nurse, within the framework of the multidisciplinary team treating the patient, in the attempt to provide optimal evaluation and care in very challenging situations (such as with terminal patients). Part 3 will provide insightful models of this new discipline and serve as a valuable resource for physicians, nurses, social workers and others involved in the care of cancer patients. The book will take a multidisciplinary approach, integrating clinical and environmental data for practical management to enhance the efficacy of treatment while relieving suffering. Part 4 will also discuss the application of modern technological approaches to track symptoms, quality of life, diet, mobility, duration of sleep and medication use (including pain killers) in chronic cancer patients in the community. Part 5 of the book will also be devoted to modes of developing a collaborative program between governmental and non-governmental organization sectors. This includes volunteer workers in close collaboration with medical professionals for providing emotional and spiritual support, nursing care, nutritional support and empowering family caregivers. Such a model makes palliative care in the community a “people’s movement”, thus transferring part of the responsibility and ownership to the community.

Science of Ashwagandha: Preventive and Therapeutic Potentials

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Publisher : Springer
ISBN 13 : 3319591924
Total Pages : 517 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Science of Ashwagandha: Preventive and Therapeutic Potentials by : Sunil C. Kaul

Download or read book Science of Ashwagandha: Preventive and Therapeutic Potentials written by Sunil C. Kaul and published by Springer. This book was released on 2017-09-13 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapidly increasing aging population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the modern society. The complex etiologies and pathologies cause major challenges to disease treatment. On the other hand, several herbs are known for their health-caring and disease-curing activities. Ashwagandha, a popular herb in Indian traditional home medicine, Ayurveda, has gathered increasing recognition in recent years when the chemically synthesized drugs for single target therapies showed limited success and adverse toxic effects. Ashwagandha is known as a powerful adaptogen and trusted to enhance function of the brain, reproductive system, cell-mediated immunity and increase the body's defense against disease, and possess anti-inflammatory, anticancer and anti-arthritic activities. In this book, for the first time, we provide a complete portrait on scientific understanding of the effects of Ashwagandha and its active principles for a variety of preventive and therapeutic activities.

The First Outstanding 50 Years of “Università Politecnica delle Marche”

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Publisher : Springer Nature
ISBN 13 : 3030338797
Total Pages : 218 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis The First Outstanding 50 Years of “Università Politecnica delle Marche” by : Sauro Longhi

Download or read book The First Outstanding 50 Years of “Università Politecnica delle Marche” written by Sauro Longhi and published by Springer Nature. This book was released on 2020-01-03 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes significant multidisciplinary research findings at the Università Politecnica delle Marche and the expected future advances. It addresses some of the most dramatic challenges posed by today’s fast-growing, global society and the changes it has caused, while also discussing solutions to improve the wellbeing of human beings. The book covers the main research achievements made in the social sciences and humanities, and includes chapters that focus on understanding mechanisms that are relevant to all aspects of economic and social interactions among individuals. In line with Giorgio Fuà’s contribution, the interdisciplinary research being pursued at the Faculty of Economics of Università Politecnica delle Marche is aimed at interpreting the process of economic development in all of its facets, both at the national and local level, with a particular focus on profit and non-profit organizations. Various disciplines are covered, from economics to sociology, history, statistics, mathematics, law, accounting, finance and management.

EBMT HANDBOOK

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Publisher :
ISBN 13 : 9783031440823
Total Pages : 0 pages
Book Rating : 4.4/5 (48 download)

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Book Synopsis EBMT HANDBOOK by :

Download or read book EBMT HANDBOOK written by and published by . This book was released on 2025 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis

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Publisher : Springer Nature
ISBN 13 : 3030291685
Total Pages : 564 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis by : Padma V. Devarajan

Download or read book Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis written by Padma V. Devarajan and published by Springer Nature. This book was released on 2019-11-09 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.

Immunophenotyping

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Publisher : Humana
ISBN 13 : 9781493996490
Total Pages : 375 pages
Book Rating : 4.9/5 (964 download)

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Book Synopsis Immunophenotyping by : J Philip McCoy Jr

Download or read book Immunophenotyping written by J Philip McCoy Jr and published by Humana. This book was released on 2019-09-29 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the latest collection of immunophenotypic techniques and applications used in research and clinical settings. Chapters in this book cover topics such as constructions of high dimensions fluorescence and mass cytometry panels; fluorescence barcoding; using dried or lyophilized reagents; and immunophenotypic examples of specific cell types. The book concludes with a discussion on the critical roles of quality control and immunophenotyping in the clinical environment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Immunophenotyping: Methods and Protocols is a valuable resource for any researchers, clinician, or scientist interested in learning more about this evolving field.

Biomarkers for Immunotherapy of Cancer

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Publisher : Humana
ISBN 13 : 9781493997725
Total Pages : 0 pages
Book Rating : 4.9/5 (977 download)

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Book Synopsis Biomarkers for Immunotherapy of Cancer by : Magdalena Thurin

Download or read book Biomarkers for Immunotherapy of Cancer written by Magdalena Thurin and published by Humana. This book was released on 2019-09-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the immune oncology (IO) community with a deeper understanding of the scope of the biomarker methods to potentially improve the outcome from immunotherapy. The editors secured the input from experts in the field dedicated to translating scientific research from bench to bedside was submitted. The book provides not only details about the technical, standardization and interpretation aspects of the methods but also introduces the reader to the background information and scientific justification for selected biomarkers and assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Therapeutic Nuclear Medicine

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Publisher : Springer
ISBN 13 : 3540367195
Total Pages : 922 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Therapeutic Nuclear Medicine by : Richard P. Baum

Download or read book Therapeutic Nuclear Medicine written by Richard P. Baum and published by Springer. This book was released on 2014-08-16 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.

Immune Mediated Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 0387720057
Total Pages : 452 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Immune Mediated Diseases by : Michael R Shurin

Download or read book Immune Mediated Diseases written by Michael R Shurin and published by Springer Science & Business Media. This book was released on 2007-09-23 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; Moscow, Russia) who were eager to share some of the academic and clinical enthusiasm that defines the IMD meetings. The goal of the International Immune-Mediated Diseases: From Theory to Therapy (IMD) Congress is to bring the world’s best immunologists and clinicians to Moscow.

Environmental Biotechnology Volume 4

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Publisher : Springer Nature
ISBN 13 : 3030777952
Total Pages : 269 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Environmental Biotechnology Volume 4 by : K. M. Gothandam

Download or read book Environmental Biotechnology Volume 4 written by K. M. Gothandam and published by Springer Nature. This book was released on 2021-09-24 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the production of bioplastic from various raw materials and recycling wastewater into useful bioproducts by bacteria. In addition, it also addresses the recent advancement in pest control in rice plants, different methods to analyse genotoxicity on soil samples and the effect of phytocompounds on acrylamide-induced toxicity in Drosophilla. Interestingly, this book also discusses mesoporous silica nanoparticles' role as nanocarrier material for inhibiting the cancer cell, especially breast cancer and various biotechnological applications of marine fungal exopolysaccharides.