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Dancing Protein Clouds Intrinsically Disordered Proteins In The Norm And Pathology Part C
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Book Synopsis Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C by :
Download or read book Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C written by and published by Academic Press. This book was released on 2021-10-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more. Provides recent studies on the intrinsically disordered proteins and their functions, along with the involvement of intrinsically disordered proteins in the pathogenesis of various diseases Contains numerous illustrative materials (color figures, diagrams and tables) to help readers delve into the information provided Includes contributions from recognized experts in the field
Book Synopsis Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C by :
Download or read book Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C written by and published by Academic Press. This book was released on 2021-10-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more.
Book Synopsis Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology by : Vladimir Uversky
Download or read book Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology written by Vladimir Uversky and published by Academic Press. This book was released on 2019-09-15 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain. Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases Contains numerous illustrative materials (color figures, diagrams, and tables) to help the readers to delve in the information provided Includes contributions from recognized experts in the field
Book Synopsis Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B by :
Download or read book Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B written by and published by Academic Press. This book was released on 2020-08-19 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B, represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain. Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases Contains numerous illustrative materials (color figures, diagrams, and tables) to help the readers to delve in the information provided Includes contributions from recognized experts in the field
Book Synopsis Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B by :
Download or read book Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B written by and published by Academic Press. This book was released on 2020-08-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B, represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.
Book Synopsis Structure and Intrinsic Disorder in Enzymology by : Munishwar Nath Gupta
Download or read book Structure and Intrinsic Disorder in Enzymology written by Munishwar Nath Gupta and published by Elsevier. This book was released on 2022-11-17 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure and Intrinsic Disorder in Enzymology offers a direct, yet comprehensive presentation of the fundamental concepts, characteristics and functions of intrinsically disordered enzymes, along with valuable notes and technical insights powering new research in this emerging field. Here, more than twenty international experts examine protein flexibility and cryo-enzymology, hierarchies of intrinsic disorder, methods for measurement of disorder in proteins, bioinformatics tools for predictions of structure, disorder and function, protein promiscuity, protein moonlighting, globular enzymes, intrinsic disorder and allosteric regulation, protein crowding, intrinsic disorder in post-translational, and much more. Chapters also review methods for study, as well as evolving technology to support new research across academic, industrial and pharmaceutical labs. Unifies the roles of intrinsic disorder and structure in the functioning of enzymes and proteins Examines a range of enzyme and protein characteristics, their relationship to intrinsic disorder, and methods for study Features chapter contributions from international leaders in the field
Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee
Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
Book Synopsis Psychic Self-Defense by : Dion Fortune
Download or read book Psychic Self-Defense written by Dion Fortune and published by Phoemixx Classics Ebooks. This book was released on 2021-12-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychic Self-Defense Dion Fortune - "Psychic Self-Defense" is one of the best guides to detection and defence against psychic attack from one of the leading occult writers of the 20th century. After finding herself the subject of a powerful psychic attack in the 1930's, famed British occultist Dion Fortune wrote this detailed instruction manual on protecting oneself from paranormal attack. This classic psychic self-defence guide explains how to understand the signs of a psychic attack, vampirism, hauntings, and methods of defence. Everything you need to know about the methods, motives, and physical aspects of a psychic attack and how to overcome it is here, along with a look at the role psychic elements play in mental illness and how to recognise them.
Book Synopsis Molecular Genetic Pathology by : Liang Cheng
Download or read book Molecular Genetic Pathology written by Liang Cheng and published by Springer. This book was released on 2013-03-05 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
Book Synopsis Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by : M. A. Hayat
Download or read book Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging written by M. A. Hayat and published by Academic Press. This book was released on 2016-12-28 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. Presents the most advanced information regarding the role of the autophagic system in life and death Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available
Book Synopsis Intrinsically Disordered Proteins by : Vladimir N. Uversky
Download or read book Intrinsically Disordered Proteins written by Vladimir N. Uversky and published by Springer. This book was released on 2014-08-05 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.
Download or read book Neurogenetics written by and published by Elsevier. This book was released on 2018-01-09 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. Contains comprehensive coverage of neurogenetics Details the latest science and its impact on our understanding of neurological, psychiatric disorders Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Book Synopsis Handbook of Sports Medicine and Science by : Jonathan C. Reeser
Download or read book Handbook of Sports Medicine and Science written by Jonathan C. Reeser and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This addition to the Handbook series is presented in five sections. The first sections covers basic and applied science, including biomechanics, the physiologic demands of volleyball, conditioning and nutrition. The second section looks at the role of the medical professional in volleyball, covering team physicians, pre-participation examination, medical equipment at courtside and emergency planning. The third section looks at injuries - including prevention, epidemiology, upper and lower limb injuries and rehabilitation. The next section looks at those volleyball players who require special consideration: the young, the disabled, and the elite, as well as gender issues. Finally, section five looks at performance enhancement.
Book Synopsis Biochemistry and Cell Biology of Ageing: Part I Biomedical Science by : J. Robin Harris
Download or read book Biochemistry and Cell Biology of Ageing: Part I Biomedical Science written by J. Robin Harris and published by Springer. This book was released on 2019-02-18 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume in the Subcellular Biochemistry series will focus on the biochemistry and cellular biology of aging processes in human cells. The chapters will be written by experts in their respective fields and will focus on a number of the current key areas of research in subcellular aging research. Main topics for discussion are mitochondrial aging, protein homeostasis and aging and the genetic processes that are involved in aging. There will also be chapters that are dedicated to the study of the roles of a variety of vitamins and minerals on aging and a number of other external factors (microbiological, ROS, inflammation, nutrition). This book will provide the reader with a state of the art overview of the subcellular aging field. This book will be published in cooperation with a second volume that will discuss the translation of the cell biology of aging to a more clinical setting and it is hoped that the combination of these two volumes will bring a deeper understanding of the links between the cell and the body during aging.
Book Synopsis Structural Biology in Drug Discovery by : Jean-Paul Renaud
Download or read book Structural Biology in Drug Discovery written by Jean-Paul Renaud and published by John Wiley & Sons. This book was released on 2020-01-09 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
Book Synopsis Staying with the Trouble by : Donna J. Haraway
Download or read book Staying with the Trouble written by Donna J. Haraway and published by Duke University Press. This book was released on 2016-08-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the midst of spiraling ecological devastation, multispecies feminist theorist Donna J. Haraway offers provocative new ways to reconfigure our relations to the earth and all its inhabitants. She eschews referring to our current epoch as the Anthropocene, preferring to conceptualize it as what she calls the Chthulucene, as it more aptly and fully describes our epoch as one in which the human and nonhuman are inextricably linked in tentacular practices. The Chthulucene, Haraway explains, requires sym-poiesis, or making-with, rather than auto-poiesis, or self-making. Learning to stay with the trouble of living and dying together on a damaged earth will prove more conducive to the kind of thinking that would provide the means to building more livable futures. Theoretically and methodologically driven by the signifier SF—string figures, science fact, science fiction, speculative feminism, speculative fabulation, so far—Staying with the Trouble further cements Haraway's reputation as one of the most daring and original thinkers of our time.
Book Synopsis Forty Studies that Changed Psychology by : Roger R. Hock
Download or read book Forty Studies that Changed Psychology written by Roger R. Hock and published by Prentice Hall. This book was released on 2005 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Biology and Human Behavior. One Brain or Two, Gazzaniga, M.S. (1967). The split brain in man. More Experience = Bigger Brain? Rosenzweig, M.R., Bennett, E.L. & Diamond M.C. (1972). Brain changes in response to experience. Are You a Natural? Bouchard, T., Lykken, D., McGue, M., Segal N., & Tellegen, A. (1990). Sources of human psychological difference: The Minnesota study of twins raised apart. Watch Out for the Visual Cliff! Gibson, E.J., & Walk, R.D. (1960). The visual cliff. 2. Perception and Consciousness. What You See Is What You've Learned. Turnbull C.M. (1961). Some observations regarding the experience and behavior of the BaMuti Pygmies. To Sleep, No Doubt to Dream... Aserinsky, E. & Kleitman, N. (1953). Regularly occurring periods of eye mobility and concomitant phenomena during sleep. Dement W. (1960). The effect of dream deprivation. Unromancing the Dream... Hobson, J.A. & McCarley, R.W. (1977). The brain as a dream-state generator: An activation-synthesis hypothesis of the dream process. Acting as if You Are Hypnotized Spanos, N.P. (1982). Hypnotic behavior: A cognitive, social, psychological perspective. 3. Learning and Conditioning. It's Not Just about Salivating Dogs! Pavlov, I.P.(1927). Conditioned reflexes. Little Emotional Albert. Watson J.B. & Rayner, R. (1920). Conditioned emotional responses. Knock Wood. Skinner, B.F. (1948). Superstition in the pigeon. See Aggression...Do Aggression! Bandura, A., Ross, D. & Ross, S.A. (1961). Transmission of aggression through imitation of aggressive models. 4. Intelligence, Cognition, and Memory. What You Expect Is What You Get. Rosenthal, R. & Jacobson, L. (1966). Teacher's expectancies: Determinates of pupils' IQ gains. Just How are You Intelligent? H. Gardner, H. (1983). Frames of mind: The theory of multiple intelligences. Maps in Your Mind. Tolman, E.C. (1948). Cognitive maps in rats and men. Thanks for the Memories. Loftus, E.F. (1975). Leading questions and the eyewitness report. 5. Human Development. Discovering Love. Harlow, H.F.(1958). The nature of love. Out of Sight, but Not Out of Mind. Piaget, J. (1954). The construction of reality in the child: The development of object concept. How Moral are You? Kohlberg, L.., (1963). The development of children's orientations toward a moral order: Sequence in the development of moral thought. In Control and Glad of It! Langer, E.J. & Rodin, J. (1976). The effects of choice and enhanced responsibility for the aged: A field experiment in an institutional setting. 6. Emotion and Motivation. A Sexual Motivation... Masters, W.H. & Johnson, V.E. (1966). Human sexual response. I Can See It All Over Your Face! Ekman, P. & Friesen, V.W. (1971). Constants across cultures in the face and emotion. Life, Change, and Stress. Holmes, T.H. & Rahe, R.H. (1967). The Social Readjustment Rating Scale. Thoughts Out of Tune. Festinger, L. & Carlsmith, J.M. (1959). Cognitive consequences of forced compliance. 7. Personality. Are You the Master of Your Fate? Rotter, J.B. (1966). Generalized expectancies for internal versus external control of reinforcement. Masculine or Feminine or Both? Bem, S.L. (1974). The measurement of psychological androgyny. Racing Against Your Heart. Friedman, M. & Rosenman, R.H. (1959). Association of specific overt behavior pattern with blood and cardiovascular findings. The One; The Many..., Triandis, H., Bontempo, R., Villareal, M., Asai, M. & Lucca, N. (1988). Individualism and collectivism: Cross-cultural perspectives on self-ingroup relationships. 8. Psychopathology. Who's Crazy Here, Anyway? Rosenhan, D.L. (1973). On Being sane in insane places. Learning to Be Depressed. Seligman, M.E.P., & Maier, S.F. (1967). Failure to escape traumatic shock. You're Getting Defensive Again! Freud, A. (1946). The ego and mechanisms of defense. Crowding into the Behavioral Sink. Calhoun, J.B. (1962). Population density and social pathology. 9. Psychotherapy. Choosing Your Psychotherapist. Smith, M.L. & Glass, G.V. (1977). Meta-analysis of psychotherapy outcome studies. Relaxing Your Fears Away. Wolpe, J. (1961). The systematic desensitization of neuroses. Projections of Who You Are. Rorschach, H. (1942). Psychodiagnostics: A diagnostic test based on perception. Picture This! Murray, H.A. (1938). Explorations in personality. 10. Social Psychology. Not Practicing What You Preach. LaPiere, R.T. (1934). Attitudes and actions. The Power of Conformity. Asch, S.E. (1955). Opinions and social pressure. To Help or Not to Help. Darley, J.M. & Latané, B. (1968). Bystander intervention in emergencies: Diffusion of responsibility. Obey at Any Cost. Milgram, S. (1963). Behavioral study of obedience.
