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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Catarina R. Almeida
Publisher : Frontiers Media SA
ISBN 13 : 2889635740
Total Pages : 204 pages
Book Rating : 4.8/5 (896 download)
Download or read book Immunomodulation of Innate Immune Cells written by Catarina R. Almeida and published by Frontiers Media SA. This book was released on 2020-03-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : John D. Lambris
Publisher : Springer Science & Business Media
ISBN 13 : 0387717676
Total Pages : 456 pages
Book Rating : 4.3/5 (877 download)
Download or read book Current Topics in Innate Immunity written by John D. Lambris and published by Springer Science & Business Media. This book was released on 2007-09-07 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the post genomic era, understanding of the innate immune system is enriched by findings on the specificity of innate immune reactions as well as to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. This volume covers natural killer cells, mast cells, phagocytes, toll-like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms, pathophysiology, protein structures, design of therapeutics, and experimental approaches.
Author : Kenneth Söderhäll
Publisher : Springer Science & Business Media
ISBN 13 : 1441980598
Total Pages : 338 pages
Book Rating : 4.4/5 (419 download)
Download or read book Invertebrate Immunity written by Kenneth Söderhäll and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates
Author : Irving C. Allen
Publisher : Humana
ISBN 13 : 9781493960361
Total Pages : 0 pages
Book Rating : 4.9/5 (63 download)
Download or read book Mouse Models of Innate Immunity written by Irving C. Allen and published by Humana. This book was released on 2016-08-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The innate immune system represents a critical arm of the immune response by providing immediate and robust host defense; however, human studies of its function are often limited by ethical, logistical, and technical obstacles. In Mouse Models of Innate Immunity: Methods and Protocols, experts in the field explore the design and execution of experiments used to thoroughly evaluate critical elements associated with the host innate immune response. The volume opens with methods that are essential for collecting and assessing various primary cells that are highly relevant to innate immunity, and it continues with in vivo protocols commonly used to evaluate the innate immune response in the mouse, including mouse models of respiratory infection, gastrointestinal inflammation, fungal and parasitic diseases, sepsis, and HIV-1 infection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Mouse Models of Innate Immunity: Methods and Protocols will serve the research community by providing expert advice and protocols that allow both experienced and novice investigators to successfully plan, implement, and assess disease processes associated with the innate immune response.
Author : Chien-Kuo Lee
Publisher : Frontiers Media SA
ISBN 13 : 2889631257
Total Pages : 221 pages
Book Rating : 4.8/5 (896 download)
Download or read book STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets written by Chien-Kuo Lee and published by Frontiers Media SA. This book was released on 2019-10-21 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mark Hulett
Publisher : Frontiers Media SA
ISBN 13 : 2889666670
Total Pages : 399 pages
Book Rating : 4.8/5 (896 download)
Download or read book Advances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond written by Mark Hulett and published by Frontiers Media SA. This book was released on 2021-04-07 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309180686
Total Pages : 102 pages
Book Rating : 4.3/5 (91 download)
Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Author : Margaret Ackerman
Publisher : Academic Press
ISBN 13 : 0123948185
Total Pages : 376 pages
Book Rating : 4.1/5 (239 download)
Download or read book Antibody Fc written by Margaret Ackerman and published by Academic Press. This book was released on 2013-08-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cancer and infectious disease to autoimmunity. Researchers have long understood the variable domain of antibodies, which are responsible for antigen recognition, and can provide protection by blocking the function of their target antigen. However, recent developments in our understanding of the protection mediated by antibodies have highlighted the critical nature of the antibody constant, or Fc domain, in the biological activity of antibodies. The Fc domain allows antibodies to link the adaptive and innate immune systems, providing specificity to a wide range of innate effector cells. In addition, they provide a feedback loop to regulate the character of the immune response via interactions with B cells and antigen-presenting cells. - Clarifies the different mechanisms of IgG activity at the level of the different model systems used, including human genetic, mouse, and in vitro - Covers the role of antibodies in cancer, infectious disease, and autoimmunity and in the setting of monoclonal antibody therapy as well as naturally raised antibodies - Color illustrations enhance explanations of the immune system
Author : Robert Jack
Publisher : Springer
ISBN 13 : 3030186679
Total Pages : 156 pages
Book Rating : 4.0/5 (31 download)
Download or read book Evolutionary Concepts in Immunology written by Robert Jack and published by Springer. This book was released on 2019-06-13 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up. Starting from Dobzhansky’s famous slogan, “Nothing in biology makes sense except in the light of evolution”, this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge.
Author : Thomas A. Kufer
Publisher : Frontiers Media SA
ISBN 13 : 2889196216
Total Pages : 222 pages
Book Rating : 4.8/5 (891 download)
Download or read book NLR-protein functions in immunity written by Thomas A. Kufer and published by Frontiers Media SA. This book was released on 2015-07-08 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nod-like receptor (NLR) family of proteins are evolutionary conserved molecules that in plants and mammals have been implicated in innate immune sensing of microbes and infection-associated physiological changes, contributing to immune protection of the challenged host organism through the instruction of inflammatory responses, antimicrobial defense and adaptive immunity. Recent data however suggests that the biological roles of NLR go beyond the function of classical pattern recognition molecules (PRM) as they have been implicated in essential cellular processes including autophagy, apoptosis, modification of signal transduction and gene transcription as well as reproductive biology. In this research topic, we aim to provide a comprehensive state-of the art overview of the emerging functions of NLR in plant and mammalian immunity, cell biology and reproductive biology. Potential topics may include, but are not limited to the following areas: • Functions of NLRs as PRMs in infection • Cross-talk of NLRs with other PRMs • Signal transduction pathways of NLRs • New functions of NLRs other than pattern recognition • Structural aspects of NLR activation • Mechanisms of NLRs in cell biological processes • Aspects of NLRs in reproductive biology • Functions of NLRs in plant immune responses
Author : Avi-Hai Hovav
Publisher : Frontiers Media SA
ISBN 13 : 2889711358
Total Pages : 164 pages
Book Rating : 4.8/5 (897 download)
Download or read book Recent Advances in Oral Immunity written by Avi-Hai Hovav and published by Frontiers Media SA. This book was released on 2021-08-03 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The oral mucosa is a challenging environment from an immunological perspective, containing discrete niches with a unique architecture and function that requires precise adjustment of the immune system. Being the port of entry to the gastrointestinal and respiratory tracts, the oral cavity is also constantly challenged by antigens derived from air and food. Moreover, the oral cavity is the sole tissue of the body harboring a hard surface (i.e. the tooth) that is exposed to the hostile external environment, resulting in the formation of a complex biofilm that has local and systemic effects. To deal with such challenges, the oral immune system aims to prevent the invasion of pathogens/harmful antigens and to tolerate non-pathogenic counterparts in order to maintain homeostasis. In recent years, numerous studies have addressed these fundamental issues, revealing sophisticated mechanisms engaged by the immune system to maintain oral mucosal homeostasis and to combat various immunological insults. Some of these studies have identified novel immunological mechanisms, emphasizing the uniqueness of the oral immune system and the necessity to further investigate its functions.
Author : Tomi Monie
Publisher : Academic Press
ISBN 13 : 9780128044643
Total Pages : 0 pages
Book Rating : 4.0/5 (446 download)
Download or read book The Innate Immune System written by Tomi Monie and published by Academic Press. This book was released on 2017-02-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Innate Immune System: A Compositional and Functional Perspective focuses on the components and functionality of the innate immune system, detailing how they work in their own right, and then progressing to cover their relevance to disease and how they interface with the adaptive response. Despite the growing appreciation of the importance of the innate immune system, many classical immunology books still focus predominantly on the adaptive immune response. Not only is this unbalanced, but it fails to reflect the growing synergy between the activation and function of the innate response and the final nature of adaptive response. This book fills the gap in knowledge that is needed to fully understand and appreciate the topic.
Author : Shailendra K. Saxena
Publisher : BoD – Books on Demand
ISBN 13 : 1838807659
Total Pages : 416 pages
Book Rating : 4.8/5 (388 download)
Download or read book Innate Immunity in Health and Disease written by Shailendra K. Saxena and published by BoD – Books on Demand. This book was released on 2021-08-25 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
Author : Bernd Lepenies
Publisher : Frontiers Media SA
ISBN 13 : 2889632555
Total Pages : 239 pages
Book Rating : 4.8/5 (896 download)
Download or read book Lectins and Their Ligands in Shaping Immune Responses written by Bernd Lepenies and published by Frontiers Media SA. This book was released on 2019-12-23 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : M.D. Cooper
Publisher : Springer Science & Business Media
ISBN 13 : 9783540428947
Total Pages : 140 pages
Book Rating : 4.4/5 (289 download)
Download or read book The Interface Between Innate and Acquired Immunity written by M.D. Cooper and published by Springer Science & Business Media. This book was released on 2002-03-26 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: All multicellular organisms may possess innate immunity mediated by defense mechanisms with which the organism is born. In recent years much has been learned about the diversity of innate immune mechanisms. A large array of naturally produced antimicrobial peptides has been de fined. A variety of cell surface receptors that recognize common patterns displayed by infectious organisms have been identified along with the intracellular pathways that these receptors use to activate cellular defense functions. Cell surface receptors on natural killer (NK) cells have been shown to sense microbial invasion in neighboring cells, thereby setting into motion their elimination by cy totoxic mechanisms. Other receptors have been found to facilitate phagocytosis and intracellular killing of microbes by phagocytic cells. These and other natural defense mechanisms have traditionally been viewed as the first line of body defense in vertebrate species that also possess the capacity for acquired or adaptive immunity. Sharks and all of the other jawed vertebrates generate large repertoires of T and B lymphocyte clones that display different antigen specific receptors in the form ofT cell receptors (TCR) and immunoglobulins (Ig) that allow them to recognize and respond to antigens in collaboration with antigen-present ing cells. Memory T and B cells are then generated to allow faster and heightened cellular and humoral immune re sponses on secondary antigen encounter. In recent years it has also become obvious that innate immune responses can directly influence adaptive immune responses in ways that will enhance body defense.
