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Current Research In Head And Neck Cancer
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Book Synopsis Current Research in Head and Neck Cancer by : Henning Bier
Download or read book Current Research in Head and Neck Cancer written by Henning Bier and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of head and neck cancer is a multistep process in which genetic as well as epigenetic alterations interfere with the regular functions of proto-oncogenes and tumor suppressor genes. In addition, carcinogenesis is promoted by the impairment of mechanisms responsible for the maintenance of genetic stability. The accumulation of crucial events such as evasion of apoptosis, lack of senescence, deregulated proliferation, invasion and metastasis, as well as neoangiogenesis eventually determines the malignant phenotype. The 16 articles of this volume span from advances in the understanding of underlying molecular pathways (conditional mouse model, folate activity, DNA repair, genomic heterogeneity, p53 family members, human papillomavirus), to preclinical and clinical studies investigating potential novel therapeutic targets (epidermal growth factor receptor, nuclear factor-kappaB, vascular endothelial growth factor, chemokine receptors, P53-based immunotherapy, virus-modified tumor vaccination), and biometric considerations on the evaluation of prognostic factors. This state-of-the-art publication is recommended reading not only for ENT specialists and oncologists, but also for molecular biologists and other subspecialists interested in head and neck cancer research.
Book Synopsis Head and Neck Cancer Imaging by : Robert Hermans
Download or read book Head and Neck Cancer Imaging written by Robert Hermans and published by Springer Science & Business Media. This book was released on 2012-01-20 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging is crucial in the multidisciplinary approach to head and neck cancer management. The rapid technological development of recent years makes it necessary for all members of the multidisciplinary team to understand the potential applications, limitations, and advantages of existing and evolving imaging technologies. It is equally important that the radiologist has sufficient clinical background knowledge to understand the clinical significance of imaging findings. This book provides an overview of the findings obtained using different imaging techniques during the evaluation of head and neck neoplasms, both before and after therapy. All anatomic areas in the head and neck are covered, and the impact of imaging on patient management is discussed in detail. The authors are recognized experts in the field, and numerous high-quality images are included. This second edition provides information on the latest imaging developments in this area, including the application of PET-CT and diffusion-weighted magnetic resonance imaging.
Book Synopsis Head and Neck Cancer by : Mark Agulnik
Download or read book Head and Neck Cancer written by Mark Agulnik and published by BoD – Books on Demand. This book was released on 2012-03-14 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Head and Neck Cancer provides an interesting and comprehensive overview of all aspects of head and neck cancer including overviews of the disease, basic science aspects pertaining to the disease, diagnosis, treatment and outcomes for patients with this disease. The chapters written by world renowned experts cover the entire discipline of head and neck oncology and include discussions of regional disparity is, advances in basic science understanding, advances in her radiotherapy, chemotherapy and targeted agents as well as a focus on reconstruction, prostheses, and aspects of quality of life and health outcomes. The book is designed to be both practical and comprehensive for every physician treating his complex disease.
Book Synopsis Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer by : Andrew F. Olshan
Download or read book Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer written by Andrew F. Olshan and published by Springer Science & Business Media. This book was released on 2010-03-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide a current perspective on the epidemiology head and neck cancer. Cancers of the oral cavity, pharynx, and larynx comprise an important group of tumors with diverse international patterns of incidence and mortality, established risk factors, suggested association with a virus, and potential genetic susceptibility determinants. These tumors offer a unique insight into mechanisms of cancer initiation and progression and gene-exposure interaction.
Book Synopsis Management of Oral Cancers by : Sudhir Bahadur
Download or read book Management of Oral Cancers written by Sudhir Bahadur and published by Springer Nature. This book was released on 2020-09-08 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor biology varies at different subsites in the oral cavity, and therefore carcinoma of the gingivo-buccal sulcus (also known as Indian cancer) behaves differently from carcinoma of the tongue. Oral cancer is very often diagnosed at an advanced stage with neck metastasis, and most cases have a guarded prognosis. Loco-regional recurrences are frequent and morbidity following treatment is considerable. However, results have improved in recent years, particularly in early and certain advanced stages, due to better imaging and case selection, improved surgical techniques, including those for reconstructive surgery, a multidisciplinary team approach and a better understanding of tumor biology and prognostic factors. This book comprehensively and systematically reviews all these aspects of diagnostic and therapeutic advances in oral cancer, particularly discussing early detection, epidemiology, chemoprevention and current research. Written by specialists who are active leaders in basic sciences or clinical fields, the chapters address individual and collective issues in managing patients with oral cancer, and provide insights into various treatment approaches. The authors share their knowledge and experience and provide extensive literature sources to encourage clinicians to be flexible, innovative and help them make the best, educated decisions for individual patients.
Book Synopsis WHO Classification of Head and Neck Tumours by : Adel K. El-Naggar
Download or read book WHO Classification of Head and Neck Tumours written by Adel K. El-Naggar and published by IARC Who Classification of Tum. This book was released on 2017-01-23 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO Classification of Head and Neck Tumours is the ninth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies evaluating response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 135 authors from 35 countries, contains more than 600 color images and tables, and more than 2700 references. This book is in the series commonly referred to as the "Blue Book" series.
Author :IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher :IARC ISBN 13 :9789283212850 Total Pages :354 pages Book Rating :4.2/5 (128 download)
Book Synopsis Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Download or read book Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC. This book was released on 2004 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A working group of sixteen experts from seven countries re-evaluated the evidence of the carcinogenicity of betel-quid and areca-nut chewing and some areca-nut related nitrosamines. Betel-quid and areca-nut chewing are widely practised in many parts of Asia and in Asian-migrant communities elsewhere in the world. There are hundreds of millions of users worldwide. They evaluated betel quid with tobacco as carcinogenic to humans (Group 1) on the basis of sufficient evidence of an increased risk of cancer of the oral cavity, pharynx and oesophagus. The working group reviewed epidemiological studies of human cancer, mainly studies from India, Pakistan and Taiwan (China). Studies on betel quid with tobacco and areca nut with tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. The working group also evaluated betel quid without tobacco as carcinogenic to humans (Group 1), on the basis of sufficient evidence of an increased risk of oral cancer. Studies on betel quid without tobacco and areca nut without tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. Areca nut, a common ingredient of betel quid and many different chewing preparations, including those available commercially, has been observed to cause oral submucous fibrosis
Book Synopsis Metastases in Head and Neck Cancer by : Jochen A. Werner
Download or read book Metastases in Head and Neck Cancer written by Jochen A. Werner and published by Springer Science & Business Media. This book was released on 2004-07-23 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: -Richly illustrated; 109 illustrations, 57 in color -Cover a wide range of diagnostic and theraputic techniques, i.e. MRI, PET, surgical treatment, radiation therapy
Book Synopsis Novel Anticancer Agents by : Alex A. Adjei
Download or read book Novel Anticancer Agents written by Alex A. Adjei and published by Academic Press. This book was released on 2006 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Anticancer Agents offers pertinent basic science information on strategies used for the rational design and discovery of novel anticancer agents, and, in addition, translational studies involving clinical trial design and execution with these novel, mostly cytostatic agents. This book covers basic science strategies that are being used in drug discovery and preclinical evaluation focused on novel molecular targets, as well as clinical trial methodology including clinical pharmacokinetics and imaging to address issues of efficacy evaluation of the new, relatively non-cytotoxic anticancer agents. At present, there is no book that provides such an integration of basic and clinical studies of novel anticancer agents, covering both drug discovery and translational research extensively. Addresses the critical issues involved in the development of novel agents for cancer therapy by experts in the field Presents drug discovery strategies Discusses regulatory issues surrounding drug development
Book Synopsis Non-melanoma Skin Cancer of the Head and Neck by : Faruque Riffat
Download or read book Non-melanoma Skin Cancer of the Head and Neck written by Faruque Riffat and published by Springer. This book was released on 2015-09-30 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-melanoma skin cancer is a global public health issue. With an ever-increasing, and ageing, world population coupled with increasing numbers of immunosuppressed individuals the number of patients continues to rise. The head and neck is overwhelmingly the most frequent location for the development of a non-melanoma skin cancer and as such challenges the clinician with its complex anatomy. The importance of maintaining the aesthetics of the face and the function of the anatomy cannot be overstated, yet ultimately it is always the aim of curing a patient with the minimum of morbidity that clinicians strive for. However, the spectrum of presentations and subsequent management varies widely, ranging from patients with the ubiquitous low-risk mid-face basal cell carcinoma to those diagnosed with relatively uncommon but potentially life-threatening high-risk squamous cell carcinomas (e.g. involving metastatic lymph nodes or with perineural invasion present) and Merkel cell carcinomas.
Book Synopsis Surgical Palliative Care by : Anne C. Mosenthal
Download or read book Surgical Palliative Care written by Anne C. Mosenthal and published by . This book was released on 2019 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Integrating Palliative Care series, this volume on surgical palliative care guides readers through the core palliative skills and knowledge needed to deliver high value care for patients with life-limiting, critical, and terminal illness under surgical care. Surgical Palliative Care is an ideal resource for surgeons, surgical nurses, intensivists, and other practitioners who wish to learn more about integrating palliative care into the surgical field.
Book Synopsis AJCC Cancer Staging Manual by : Frederick L, Greene
Download or read book AJCC Cancer Staging Manual written by Frederick L, Greene and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.
Book Synopsis Head and Neck Cancer by : John Frederick Ensley
Download or read book Head and Neck Cancer written by John Frederick Ensley and published by Elsevier. This book was released on 2003-01-07 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: By detailing experimental and basic research, from premalignancy to fully invasive tumors, this book has wide applicability to all human carcinomas. No other group of human cancers is better positioned for the application of recently developed novel and targeted therapies, and this book uniquely presents the unusual opportunities tumors of the head and neck provide for clinical, translational, and basic science research. Cutting-edge and experimental treatment approaches are presented, along with future strategies and an evaluation of emerging technologies. - Presents a multi-disciplinary perspective from authorities in diverse fields - Addresses state-of-the art approaches in cancer research as well as other scientific opportunities in this field - Provides comprehensive yet easily comprehendible source of information
Download or read book Oral Mucositis written by Stephen T Sonis and published by Springer Science & Business Media. This book was released on 2013-11-12 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment tolerance is a challenge for most cancer patients, and it is therefore essential that healthcare professionals (HCP) are quick to recognize adverse events and implement management strategies to address them. This pocket book provides an in-depth guide to the epidemiology, diagnosis and management of oral mucositis, a common adverse event of chemotherapy.
Book Synopsis Cancer of the Head and Neck by : Eugene N. Myers
Download or read book Cancer of the Head and Neck written by Eugene N. Myers and published by . This book was released on 2003 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Comprehensive...a valuable [addition] to the library of any head and neck surgeon. Of similar value to neurosurgeons dealing specifically with the skull base." --Journal of Neurosurgery. The latest edition of this definitive reference delivers state-of-the-art coverage of every aspect of head and neck cancer. Authors are all experts in their fields, with two new editors bringing fresh up-to-date perspectives. The 4th Edition takes a multidisciplinary approach to surgery and management, bringing new information on topics such as reconstruction of the vocal chords, treatment of laryngeal cancer, and radiotherapy. Features cutting-edge coverage of radiologic evaluation, including the diagnosis and progression of cancers via PET scanning. Includes new information on the treatment of cancer of the nasopharanx, plus the surgical treatment of recurrent nasopharangeal cancer. Discusses the use of combined chemotherapy and radiation to preserve the larynx in patients with advanced cancer in this area. Presents the very latest developments in the management of unusual tumors such as hemangiomas and arteriovenous malformation of the head and neck Describes five new areas of reconstruction of major defects in the head and neck following surgery: anterolateral thigh flap, palatomaxillary reconstruction, reconstruction of the cheek, posterior scalping flap, and submental island flap. Discusses the current status of immunotherapy in treating head and neck cancer.
Book Synopsis Head and Neck Cancer by : Jacques Bernier
Download or read book Head and Neck Cancer written by Jacques Bernier and published by Springer. This book was released on 2016-08-22 with total page 877 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks. In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
Book Synopsis The Economics of Cancer Care by : Nicholas Bosanquet
Download or read book The Economics of Cancer Care written by Nicholas Bosanquet and published by Cambridge University Press. This book was released on 2006-03-23 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2006 book examines the interaction of economics and the delivery of cancer care in the global context. It analyses the causes of tension between those paying for care, those providing the care and those marketing drugs and devices. The concept and requirement for rationing is examined in different economic environments. As cancer increases in incidence and prevalence, the economics of providing care becomes a more important subject than ever before. Written by a leading health economist and oncologist, this was the first comprehensive book on the economics of cancer care continues to be of interest to health professionals and policy makers alike.